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Items: 7


Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP2 Suggest a Mechanism for Regulation.

Sisco NJ, Helsell CVM, Van Horn WD.

Sci Rep. 2019 Oct 1;9(1):14128. doi: 10.1038/s41598-019-49912-5.


Phosphoinositide-interacting regulator of TRP (PIRT) has opposing effects on human and mouse TRPM8 ion channels.

Hilton JK, Salehpour T, Sisco NJ, Rath P, Van Horn WD.

J Biol Chem. 2018 Jun 15;293(24):9423-9434. doi: 10.1074/jbc.RA118.003563. Epub 2018 May 3.


Structural basis for KCNE3 modulation of potassium recycling in epithelia.

Kroncke BM, Van Horn WD, Smith J, Kang C, Welch RC, Song Y, Nannemann DP, Taylor KC, Sisco NJ, George AL Jr, Meiler J, Vanoye CG, Sanders CR.

Sci Adv. 2016 Sep 9;2(9):e1501228. doi: 10.1126/sciadv.1501228. eCollection 2016 Sep.


Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes.

Anosova I, Kowal EA, Sisco NJ, Sau S, Liao JY, Bala S, Rozners E, Egli M, Chaput JC, Van Horn WD.

Chembiochem. 2016 Sep 15;17(18):1705-8. doi: 10.1002/cbic.201600349. Epub 2016 Jul 29.


Implications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing Domain.

Rath P, Hilton JK, Sisco NJ, Van Horn WD.

Biochemistry. 2016 Jan 12;55(1):114-24. doi: 10.1021/acs.biochem.5b00931. Epub 2015 Dec 23.


Statistical removal of background signals from high-throughput (1)H NMR line-broadening ligand-affinity screens.

Worley B, Sisco NJ, Powers R.

J Biomol NMR. 2015 Sep;63(1):53-8. doi: 10.1007/s10858-015-9962-3. Epub 2015 Jul 9.


NMR Structure of Francisella tularensis Virulence Determinant Reveals Structural Homology to Bet v1 Allergen Proteins.

Zook J, Mo G, Sisco NJ, Craciunescu FM, Hansen DT, Baravati B, Cherry BR, Sykes K, Wachter R, Van Horn WD, Fromme P.

Structure. 2015 Jun 2;23(6):1116-22. doi: 10.1016/j.str.2015.03.025. Epub 2015 May 21.

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