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Items: 37

1.

Proteomic profiling of the plasma of Gambian children with cerebral malaria.

Moussa EM, Huang H, Thézénas ML, Fischer R, Ramaprasad A, Sisay-Joof F, Jallow M, Pain A, Kwiatkowski D, Kessler BM, Casals-Pascual C.

Malar J. 2018 Sep 24;17(1):337. doi: 10.1186/s12936-018-2487-y.

2.

Resistance to malaria through structural variation of red blood cell invasion receptors.

Leffler EM, Band G, Busby GBJ, Kivinen K, Le QS, Clarke GM, Bojang KA, Conway DJ, Jallow M, Sisay-Joof F, Bougouma EC, Mangano VD, Modiano D, Sirima SB, Achidi E, Apinjoh TO, Marsh K, Ndila CM, Peshu N, Williams TN, Drakeley C, Manjurano A, Reyburn H, Riley E, Kachala D, Molyneux M, Nyirongo V, Taylor T, Thornton N, Tilley L, Grimsley S, Drury E, Stalker J, Cornelius V, Hubbart C, Jeffreys AE, Rowlands K, Rockett KA, Spencer CCA, Kwiatkowski DP; Malaria Genomic Epidemiology Network.

Science. 2017 Jun 16;356(6343). pii: eaam6393. doi: 10.1126/science.aam6393. Epub 2017 May 18.

3.

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia.

Clarke GM, Rockett K, Kivinen K, Hubbart C, Jeffreys AE, Rowlands K, Jallow M, Conway DJ, Bojang KA, Pinder M, Usen S, Sisay-Joof F, Sirugo G, Toure O, Thera MA, Konate S, Sissoko S, Niangaly A, Poudiougou B, Mangano VD, Bougouma EC, Sirima SB, Modiano D, Amenga-Etego LN, Ghansah A, Koram KA, Wilson MD, Enimil A, Evans J, Amodu OK, Olaniyan S, Apinjoh T, Mugri R, Ndi A, Ndila CM, Uyoga S, Macharia A, Peshu N, Williams TN, Manjurano A, Sepúlveda N, Clark TG, Riley E, Drakeley C, Reyburn H, Nyirongo V, Kachala D, Molyneux M, Dunstan SJ, Phu NH, Quyen NN, Thai CQ, Hien TT, Manning L, Laman M, Siba P, Karunajeewa H, Allen S, Allen A, Davis TM, Michon P, Mueller I, Molloy SF, Campino S, Kerasidou A, Cornelius VJ, Hart L, Shah SS, Band G, Spencer CC, Agbenyega T, Achidi E, Doumbo OK, Farrar J, Marsh K, Taylor T, Kwiatkowski DP; MalariaGEN Consortium.

Elife. 2017 Jan 9;6. pii: e15085. doi: 10.7554/eLife.15085.

4.

Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria.

Shah SS, Rockett KA, Jallow M, Sisay-Joof F, Bojang KA, Pinder M, Jeffreys A, Craik R, Hubbart C, Wellems TE, Kwiatkowski DP; MalariaGEN Consortium.

Malar J. 2016 Jan 7;15:13. doi: 10.1186/s12936-015-1045-0.

5.

The African Genome Variation Project shapes medical genetics in Africa.

Gurdasani D, Carstensen T, Tekola-Ayele F, Pagani L, Tachmazidou I, Hatzikotoulas K, Karthikeyan S, Iles L, Pollard MO, Choudhury A, Ritchie GR, Xue Y, Asimit J, Nsubuga RN, Young EH, Pomilla C, Kivinen K, Rockett K, Kamali A, Doumatey AP, Asiki G, Seeley J, Sisay-Joof F, Jallow M, Tollman S, Mekonnen E, Ekong R, Oljira T, Bradman N, Bojang K, Ramsay M, Adeyemo A, Bekele E, Motala A, Norris SA, Pirie F, Kaleebu P, Kwiatkowski D, Tyler-Smith C, Rotimi C, Zeggini E, Sandhu MS.

Nature. 2015 Jan 15;517(7534):327-32. doi: 10.1038/nature13997. Epub 2014 Dec 3.

6.

Inactive alleles of cytochrome P450 2C19 may be positively selected in human evolution.

Janha RE, Worwui A, Linton KJ, Shaheen SO, Sisay-Joof F, Walton RT.

BMC Evol Biol. 2014 Apr 1;14:71. doi: 10.1186/1471-2148-14-71.

7.

Imputation-based meta-analysis of severe malaria in three African populations.

Band G, Le QS, Jostins L, Pirinen M, Kivinen K, Jallow M, Sisay-Joof F, Bojang K, Pinder M, Sirugo G, Conway DJ, Nyirongo V, Kachala D, Molyneux M, Taylor T, Ndila C, Peshu N, Marsh K, Williams TN, Alcock D, Andrews R, Edkins S, Gray E, Hubbart C, Jeffreys A, Rowlands K, Schuldt K, Clark TG, Small KS, Teo YY, Kwiatkowski DP, Rockett KA, Barrett JC, Spencer CC; Malaria Genomic Epidemiology Network.

PLoS Genet. 2013 May;9(5):e1003509. doi: 10.1371/journal.pgen.1003509. Epub 2013 May 23. Erratum in: PLoS Genet. 2013 Jun;9(6). doi:10.1371/annotation/adc2beaf-4bee-4e22-925b-6788d62fe029. Malaria Genomic Epidemiological Network [corrected to Malaria Genomic Epidemiology Network].

8.

Clinical features of severe malaria associated with death: a 13-year observational study in the Gambia.

Jallow M, Casals-Pascual C, Ackerman H, Walther B, Walther M, Pinder M, Sisay-Joof F, Usen S, Jallow M, Abubakar I, Olaosebikan R, Jobarteh A, Conway DJ, Bojang K, Kwiatkowski D.

PLoS One. 2012;7(9):e45645. doi: 10.1371/journal.pone.0045645. Epub 2012 Sep 28.

9.

Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia.

Dunyo S, Sirugo G, Sesay S, Bisseye C, Njie F, Adiamoh M, Nwakanma D, Diatta M, Janha R, Sisay Joof F, Temple B, Snell P, Conway D, Walton R, Cheung YB, Milligan P.

PLoS One. 2011;6(6):e17371. doi: 10.1371/journal.pone.0017371. Epub 2011 Jun 7.

10.

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.

Thye T, Vannberg FO, Wong SH, Owusu-Dabo E, Osei I, Gyapong J, Sirugo G, Sisay-Joof F, Enimil A, Chinbuah MA, Floyd S, Warndorff DK, Sichali L, Malema S, Crampin AC, Ngwira B, Teo YY, Small K, Rockett K, Kwiatkowski D, Fine PE, Hill PC, Newport M, Lienhardt C, Adegbola RA, Corrah T, Ziegler A; African TB Genetics Consortium; Wellcome Trust Case Control Consortium, Morris AP, Meyer CG, Horstmann RD, Hill AVS.

Nat Genet. 2010 Sep;42(9):739-741. doi: 10.1038/ng.639. Epub 2010 Aug 8. Erratum in: Nat Genet. 2011 Oct;43(10):1040.

11.

Prevention of the recurrence of anaemia in Gambian children following discharge from hospital.

Bojang KA, Milligan PJ, Conway DJ, Sisay-Joof F, Jallow M, Nwakanma DC, Abubakr I, Njie F, Greenwood B.

PLoS One. 2010 Jun 21;5(6):e11227. doi: 10.1371/journal.pone.0011227.

12.

Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis.

Auburn S, Fry AE, Clark TG, Campino S, Diakite M, Green A, Richardson A, Jallow M, Sisay-Joof F, Pinder M, Molyneux ME, Taylor TE, Haldar K, Rockett KA, Kwiatkowski DP.

PLoS One. 2010 Apr 1;5(4):e10017. doi: 10.1371/journal.pone.0010017.

13.

Effects of genetic variation at the CYP2C19/CYP2C9 locus on pharmacokinetics of chlorcycloguanil in adult Gambians.

Janha RE, Sisay-Joof F, Hamid-Adiamoh M, Worwui A, Chapman HL, Opara H, Dunyo S, Milligan P, Rockett K, Winstanley P, Pirmohamed M, Miller AK, Conway DJ, Walton RT.

Pharmacogenomics. 2009 Sep;10(9):1423-31. doi: 10.2217/pgs.09.72.

14.

Genome-wide and fine-resolution association analysis of malaria in West Africa.

Jallow M, Teo YY, Small KS, Rockett KA, Deloukas P, Clark TG, Kivinen K, Bojang KA, Conway DJ, Pinder M, Sirugo G, Sisay-Joof F, Usen S, Auburn S, Bumpstead SJ, Campino S, Coffey A, Dunham A, Fry AE, Green A, Gwilliam R, Hunt SE, Inouye M, Jeffreys AE, Mendy A, Palotie A, Potter S, Ragoussis J, Rogers J, Rowlands K, Somaskantharajah E, Whittaker P, Widden C, Donnelly P, Howie B, Marchini J, Morris A, SanJoaquin M, Achidi EA, Agbenyega T, Allen A, Amodu O, Corran P, Djimde A, Dolo A, Doumbo OK, Drakeley C, Dunstan S, Evans J, Farrar J, Fernando D, Hien TT, Horstmann RD, Ibrahim M, Karunaweera N, Kokwaro G, Koram KA, Lemnge M, Makani J, Marsh K, Michon P, Modiano D, Molyneux ME, Mueller I, Parker M, Peshu N, Plowe CV, Puijalon O, Reeder J, Reyburn H, Riley EM, Sakuntabhai A, Singhasivanon P, Sirima S, Tall A, Taylor TE, Thera M, Troye-Blomberg M, Williams TN, Wilson M, Kwiatkowski DP; Wellcome Trust Case Control Consortium; Malaria Genomic Epidemiology Network.

Nat Genet. 2009 Jun;41(6):657-65. doi: 10.1038/ng.388. Epub 2009 May 24.

15.

Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes.

Fry AE, Ghansa A, Small KS, Palma A, Auburn S, Diakite M, Green A, Campino S, Teo YY, Clark TG, Jeffreys AE, Wilson J, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Peshu N, Williams TN, Newton CR, Marsh K, Molyneux ME, Taylor TE, Koram KA, Oduro AR, Rogers WO, Rockett KA, Sabeti PC, Kwiatkowski DP.

Hum Mol Genet. 2009 Jul 15;18(14):2683-92. doi: 10.1093/hmg/ddp192. Epub 2009 Apr 29.

16.

TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression.

Campino S, Forton J, Auburn S, Fry A, Diakite M, Richardson A, Hull J, Jallow M, Sisay-Joof F, Pinder M, Molyneux ME, Taylor TE, Rockett K, Clark TG, Kwiatkowski DP.

Malar J. 2009 Mar 13;8:44. doi: 10.1186/1475-2875-8-44.

17.

Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations.

Clark TG, Diakite M, Auburn S, Campino S, Fry AE, Green A, Richardson A, Small K, Teo YY, Wilson J, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Rockett KA, Kwiatkowski DP.

J Infect Dis. 2009 Feb 15;199(4):569-75. doi: 10.1086/596320.

18.

Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility.

Clark TG, Fry AE, Auburn S, Campino S, Diakite M, Green A, Richardson A, Teo YY, Small K, Wilson J, Jallow M, Sisay-Joof F, Pinder M, Sabeti P, Kwiatkowski DP, Rockett KA.

Eur J Hum Genet. 2009 Aug;17(8):1080-5. doi: 10.1038/ejhg.2009.8. Epub 2009 Feb 18.

19.

Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations.

Mangano VD, Clark TG, Auburn S, Campino S, Diakite M, Fry AE, Green A, Richardson A, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Newton C, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Modiano D, Kwiatkowski DP, Rockett KA.

PLoS One. 2009;4(1):e4206. doi: 10.1371/journal.pone.0004206. Epub 2009 Jan 15.

20.

A genetic association study in the Gambia using tagging polymorphisms in the major histocompatibility complex class III region implicates a HLA-B associated transcript 2 polymorphism in severe malaria susceptibility.

Diakite M, Clark TG, Auburn S, Campino S, Fry AE, Green A, Morris AP, Richardson A, Jallow M, Sisay-Joof F, Pinder M, Kwiatkowski DP, Rockett KA.

Hum Genet. 2009 Feb;125(1):105-9. doi: 10.1007/s00439-008-0597-2. Epub 2008 Nov 28.

21.

Association of the GNAS locus with severe malaria.

Auburn S, Diakite M, Fry AE, Ghansah A, Campino S, Richardson A, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Koram KA, Oduro AR, Rogers WO, Rockett KA, Haldar K, Kwiatkowski DP.

Hum Genet. 2008 Dec;124(5):499-506. doi: 10.1007/s00439-008-0575-8. Epub 2008 Oct 26.

22.

Variation in the ICAM1 gene is not associated with severe malaria phenotypes.

Fry AE, Auburn S, Diakite M, Green A, Richardson A, Wilson J, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Rockett KA, Kwiatkowski DP.

Genes Immun. 2008 Jul;9(5):462-9. doi: 10.1038/gene.2008.38. Epub 2008 Jun 5.

23.

Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria.

Fry AE, Griffiths MJ, Auburn S, Diakite M, Forton JT, Green A, Richardson A, Wilson J, Jallow M, Sisay-Joof F, Pinder M, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Rockett KA, Kwiatkowski DP.

Hum Mol Genet. 2008 Feb 15;17(4):567-76. Epub 2007 Nov 13.

24.

A hallmark of balancing selection is present at the promoter region of interleukin 10.

Wilson JN, Rockett K, Keating B, Jallow M, Pinder M, Sisay-Joof F, Newport M, Kwiatkowski D.

Genes Immun. 2006 Dec;7(8):680-3. Epub 2006 Aug 31.

PMID:
16943796
25.

Implications of inter-population linkage disequilibrium patterns on the approach to a disease association study in the human MHC class III.

Hanchard N, Diakite M, Koch O, Keating B, Pinder M, Jallow M, Sisay-Joof F, Nijnik A, Wilson J, Udalova I, Kwiatkowski D, Rockett K.

Immunogenetics. 2006 Jun;58(5-6):465-70. Epub 2006 Apr 28.

PMID:
16738941
26.

Immunoglobulin G antibodies to merozoite surface antigens are associated with recovery from chloroquine-resistant Plasmodium falciparum in Gambian children.

Pinder M, Sutherland CJ, Sisay-Joof F, Ismaili J, McCall MB, Ord R, Hallett R, Holder AA, Milligan P.

Infect Immun. 2006 May;74(5):2887-93.

27.

A comparison of case-control and family-based association methods: the example of sickle-cell and malaria.

Ackerman H, Usen S, Jallow M, Sisay-Joof F, Pinder M, Kwiatkowski DP.

Ann Hum Genet. 2005 Sep;69(Pt 5):559-65.

28.

Population-specific patterns of linkage disequilibrium in the human 5q31 region.

Luoni G, Forton J, Jallow M, Sadighi Akha E, Sisay-Joof F, Pinder M, Hanchard N, Herbert M, Kimber M, Mott R, Hull J, Rockett K, Kwiatkowski D.

Genes Immun. 2005 Dec;6(8):723-7.

PMID:
16052173
29.

Analysis of IL10 haplotypic associations with severe malaria.

Wilson JN, Rockett K, Jallow M, Pinder M, Sisay-Joof F, Newport M, Newton J, Kwiatkowski D.

Genes Immun. 2005 Sep;6(6):462-6.

PMID:
15933743
30.

Investigation of malaria susceptibility determinants in the IFNG/IL26/IL22 genomic region.

Koch O, Rockett K, Jallow M, Pinder M, Sisay-Joof F, Kwiatkowski D.

Genes Immun. 2005 Jun;6(4):312-8.

PMID:
15858598
31.

Complex haplotypic structure of the central MHC region flanking TNF in a West African population.

Ackerman HC, Ribas G, Jallow M, Mott R, Neville M, Sisay-Joof F, Pinder M, Campbell RD, Kwiatkowski DP.

Genes Immun. 2003 Oct;4(7):476-86.

PMID:
14551600
32.

Haplotypic analysis of the TNF locus by association efficiency and entropy.

Ackerman H, Usen S, Mott R, Richardson A, Sisay-Joof F, Katundu P, Taylor T, Ward R, Molyneux M, Pinder M, Kwiatkowski DP.

Genome Biol. 2003;4(4):R24. Epub 2003 Mar 17.

33.

Nucleotide diversity of the TNF gene region in an African village.

Richardson A, Sisay-Joof F, Ackerman H, Usen S, Katundu P, Taylor T, Molyneux M, Pinder M, Kwiatkowski D.

Genes Immun. 2001 Oct;2(6):343-8.

34.

Genetic linkage of mild malaria to the major histocompatibility complex in Gambian children: study of affected sibling pairs.

Jepson A, Sisay-Joof F, Banya W, Hassan-King M, Frodsham A, Bennett S, Hill AV, Whittle H.

BMJ. 1997 Jul 12;315(7100):96-7.

35.

Analysis of the T-cell receptor V beta usage in monozygotic and dizygotic twins living in a Plasmodium falciparum endemic area in west Africa.

Troye-Blomberg M, Fogdell A, el-Ghazali G, Larsson A, King MH, Sisay-Joof F, Olerup O, Grunewald J, Jepson A.

Scand J Immunol. 1997 May;45(5):541-5.

36.

Quantification of the relative contribution of major histocompatibility complex (MHC) and non-MHC genes to human immune responses to foreign antigens.

Jepson A, Banya W, Sisay-Joof F, Hassan-King M, Nunes C, Bennett S, Whittle H.

Infect Immun. 1997 Mar;65(3):872-6.

37.

Genetic regulation of fever in Plasmodium falciparum malaria in Gambian twin children.

Jepson AP, Banya WA, Sisay-Joof F, Hassan-King M, Bennett S, Whittle HC.

J Infect Dis. 1995 Jul;172(1):316-9.

PMID:
7797941

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