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Arenavirus genomics: novel insights into viral diversity, origin, and evolution.

Pontremoli C, Forni D, Sironi M.

Curr Opin Virol. 2018 Nov 26;34:18-28. doi: 10.1016/j.coviro.2018.11.001. [Epub ahead of print] Review.


On the molecular optical nonlinearity of halogen-bond-forming azobenzenes.

Virkki M, Maurice A, Forni A, Sironi M, Dichiarante V, Brevet PF, Metrangolo P, Kauranen M, Priimagi A.

Phys Chem Chem Phys. 2018 Nov 21;20(45):28810-28817. doi: 10.1039/c8cp05392h.


Synergy of cytological methods in the pathological staging of breast cancer: Axillary fine-needle aspiration and intraoperative scrape cytology of the sentinel lymph node.

Bruzzone M, Saro F, Bruno S, Celiento T, Mazzarella G, Lanata S, Aquilano MC, Parmigiani G, Pollone M, Gandolfo F, Costigliolo G, Sironi M.

Diagn Cytopathol. 2018 Nov;46(11):919-926. doi: 10.1002/dc.23995. Epub 2018 Oct 24.


Corrigendum to "Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation" [Biochim. Biophys. Acta, 1862 (2016) 1182-1190].

Bonacina F, Barbieri SS, Cutuli L, Amadi P, Don A, Sironi M, Tartari S, Mantovani A, Bottazzi B, Garlanda C, Tremoli E, Catapano AL, Norata GD.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):262. doi: 10.1016/j.bbadis.2018.09.017. Epub 2018 Oct 16. No abstract available.


First assessment of persistent organic pollutant contamination in blubber of Chilean blue whales from Isla de Chiloé, southern Chile.

Muñoz-Arnanz J, Chirife AD, Galletti Vernazzani B, Cabrera E, Sironi M, Millán J, Attard CRM, Jiménez B.

Sci Total Environ. 2019 Feb 10;650(Pt 1):1521-1528. doi: 10.1016/j.scitotenv.2018.09.070. Epub 2018 Sep 6.


Genetic conflicts with Plasmodium parasites and functional constraints shape the evolution of erythrocyte cytoskeletal proteins.

Sironi M, Forni D, Clerici M, Cagliani R.

Sci Rep. 2018 Oct 2;8(1):14682. doi: 10.1038/s41598-018-33049-y.


The Diversity of Mammalian Hemoproteins and Microbial Heme Scavengers Is Shaped by an Arms Race for Iron Piracy.

Mozzi A, Forni D, Clerici M, Cagliani R, Sironi M.

Front Immunol. 2018 Sep 11;9:2086. doi: 10.3389/fimmu.2018.02086. eCollection 2018.


Lifetime glucocorticoid profiles in baleen of right whale calves: potential relationships to chronic stress of repeated wounding by Kelp Gulls.

Fernández Ajó AA, Hunt KE, Uhart M, Rowntree V, Sironi M, Marón CF, Di Martino M, Buck CL.

Conserv Physiol. 2018 Aug 20;6(1):coy045. doi: 10.1093/conphys/coy045. eCollection 2018.


X-ray Constrained Spin-Coupled Wavefunction: a New Tool to Extract Chemical Information from X-ray Diffraction Data.

Genoni A, Franchini D, Pieraccini S, Sironi M.

Chemistry. 2018 Oct 17;24(58):15507-15511. doi: 10.1002/chem.201803988. Epub 2018 Sep 26.


Strategy of Human Cytomegalovirus To Escape Interferon Beta-Induced APOBEC3G Editing Activity.

Pautasso S, Galitska G, Dell'Oste V, Biolatti M, Cagliani R, Forni D, De Andrea M, Gariglio M, Sironi M, Landolfo S.

J Virol. 2018 Sep 12;92(19). pii: e01224-18. doi: 10.1128/JVI.01224-18. Print 2018 Oct 1.


Analysis of Reptarenavirus genomes indicates different selective forces acting on the S and L segments and recent expansion of common genotypes.

Pontremoli C, Forni D, Cagliani R, Sironi M.

Infect Genet Evol. 2018 Oct;64:212-218. doi: 10.1016/j.meegid.2018.06.031. Epub 2018 Jun 30.


Evolutionary rates of mammalian telomere-stability genes correlate with karyotype features and female germline expression.

Pontremoli C, Forni D, Cagliani R, Pozzoli U, Clerici M, Sironi M.

Nucleic Acids Res. 2018 Aug 21;46(14):7153-7168. doi: 10.1093/nar/gky494.


The influence of DCDC2 risk genetic variants on reading: Testing main and haplotypic effects.

Riva V, Mozzi A, Forni D, Trezzi V, Giorda R, Riva S, Villa M, Sironi M, Cagliani R, Mascheretti S.

Neuropsychologia. 2018 May 24. pii: S0028-3932(18)30220-3. doi: 10.1016/j.neuropsychologia.2018.05.021. [Epub ahead of print]


Multiple Selected Changes May Modulate the Molecular Interaction between Laverania RH5 and Primate Basigin.

Forni D, Pontremoli C, Cagliani R, Pozzoli U, Clerici M, Sironi M.

MBio. 2018 May 22;9(3). pii: e00476-18. doi: 10.1128/mBio.00476-18. No abstract available.


Evolutionary Analysis Provides Insight Into the Origin and Adaptation of HCV.

Forni D, Cagliani R, Pontremoli C, Pozzoli U, Vertemara J, De Gioia L, Clerici M, Sironi M.

Front Microbiol. 2018 May 1;9:854. doi: 10.3389/fmicb.2018.00854. eCollection 2018.


Imidazo[2,1-b]benzothiazol Derivatives as Potential Allosteric Inhibitors of the Glucocorticoid Receptor.

Christodoulou MS, Dapiaggi F, Ghiringhelli F, Pieraccini S, Sironi M, Lucafò M, Curci D, Decorti G, Stocco G, Chirumamilla CS, Vanden Berghe W, Balaguer P, Michel BY, Burger A, Beccalli EM, Passarella D, Martinet N.

ACS Med Chem Lett. 2018 Feb 26;9(4):339-344. doi: 10.1021/acsmedchemlett.7b00527. eCollection 2018 Apr 12.


Ancient Evolution of Mammarenaviruses: Adaptation via Changes in the L Protein and No Evidence for Host-Virus Codivergence.

Forni D, Pontremoli C, Pozzoli U, Clerici M, Cagliani R, Sironi M.

Genome Biol Evol. 2018 Mar 1;10(3):863-874. doi: 10.1093/gbe/evy050.


The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair.

Grčević D, Sironi M, Valentino S, Deban L, Cvija H, Inforzato A, Kovačić N, Katavić V, Kelava T, Kalajzić I, Mantovani A, Bottazzi B.

Front Immunol. 2018 Mar 5;9:417. doi: 10.3389/fimmu.2018.00417. eCollection 2018.


Economic Conditions of Young Adults Before and After the Great Recession.

Sironi M.

J Fam Econ Issues. 2018;39(1):103-116. doi: 10.1007/s10834-017-9554-3. Epub 2017 Oct 17.


ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity.

Massara M, Bonavita O, Savino B, Caronni N, Mollica Poeta V, Sironi M, Setten E, Recordati C, Crisafulli L, Ficara F, Mantovani A, Locati M, Bonecchi R.

Nat Commun. 2018 Feb 14;9(1):676. doi: 10.1038/s41467-018-03080-8.


Origin and dispersal of Hepatitis E virus.

Forni D, Cagliani R, Clerici M, Sironi M.

Emerg Microbes Infect. 2018 Feb 7;7(1):11. doi: 10.1038/s41426-017-0009-6.


Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination.

Haks MC, Bottazzi B, Cecchinato V, De Gregorio C, Del Giudice G, Kaufmann SHE, Lanzavecchia A, Lewis DJM, Maertzdorf J, Mantovani A, Sallusto F, Sironi M, Uguccioni M, Ottenhoff THM.

Front Immunol. 2017 Nov 15;8:1563. doi: 10.3389/fimmu.2017.01563. eCollection 2017. Review.


Genetic susceptibility to infectious diseases: Current status and future perspectives from genome-wide approaches.

Mozzi A, Pontremoli C, Sironi M.

Infect Genet Evol. 2018 Dec;66:286-307. doi: 10.1016/j.meegid.2017.09.028. Epub 2017 Sep 22.


REST, a master regulator of neurogenesis, evolved under strong positive selection in humans and in non human primates.

Mozzi A, Guerini FR, Forni D, Costa AS, Nemni R, Baglio F, Cabinio M, Riva S, Pontremoli C, Clerici M, Sironi M, Cagliani R.

Sci Rep. 2017 Aug 25;7(1):9530. doi: 10.1038/s41598-017-10245-w.


Dimensions of sexual orientation and sleep disturbance among young adults.

Fricke J, Sironi M.

Prev Med Rep. 2017 Aug 5;8:18-24. doi: 10.1016/j.pmedr.2017.07.008. eCollection 2017 Dec.


Evolutionary analysis of Old World arenaviruses reveals a major adaptive contribution of the viral polymerase.

Pontremoli C, Forni D, Cagliani R, Pozzoli U, Riva S, Bravo IG, Clerici M, Sironi M.

Mol Ecol. 2017 Oct;26(19):5173-5188. doi: 10.1111/mec.14282. Epub 2017 Sep 5.


Distinct selective forces and Neanderthal introgression shaped genetic diversity at genes involved in neurodevelopmental disorders.

Mozzi A, Forni D, Cagliani R, Pozzoli U, Clerici M, Sironi M.

Sci Rep. 2017 Jul 21;7(1):6116. doi: 10.1038/s41598-017-06440-4.


A common genetic variant in FOXP2 is associated with language-based learning (dis)abilities: Evidence from two Italian independent samples.

Mozzi A, Riva V, Forni D, Sironi M, Marino C, Molteni M, Riva S, Guerini FR, Clerici M, Cagliani R, Mascheretti S.

Am J Med Genet B Neuropsychiatr Genet. 2017 Apr 24. doi: 10.1002/ajmg.b.32546. [Epub ahead of print]


TLR3 Mutations in Adult Patients With Herpes Simplex Virus and Varicella-Zoster Virus Encephalitis.

Sironi M, Peri AM, Cagliani R, Forni D, Riva S, Biasin M, Clerici M, Gori A.

J Infect Dis. 2017 May 1;215(9):1430-1434. doi: 10.1093/infdis/jix166.


Intraperitoneal adoptive transfer of mesenchymal stem cells enhances recovery from acid aspiration acute lung injury in mice.

Mauri T, Zambelli V, Cappuzzello C, Bellani G, Dander E, Sironi M, Castiglioni V, Doni A, Mantovani A, Biondi A, Garlanda C, D'amico G, Pesenti A.

Intensive Care Med Exp. 2017 Dec;5(1):13. doi: 10.1186/s40635-017-0126-5. Epub 2017 Mar 6.


Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection.

Al-Daghri NM, Pontremoli C, Cagliani R, Forni D, Alokail MS, Al-Attas OS, Sabico S, Riva S, Clerici M, Sironi M.

BMC Evol Biol. 2017 Feb 7;17(1):43. doi: 10.1186/s12862-017-0897-z.


Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation.

Dander E, De Lorenzo P, Bottazzi B, Quarello P, Vinci P, Balduzzi A, Masciocchi F, Bonanomi S, Cappuzzello C, Prunotto G, Pavan F, Pasqualini F, Sironi M, Cuccovillo I, Leone R, Salvatori G, Parma M, Terruzzi E, Pagni F, Locatelli F, Mantovani A, Fagioli F, Biondi A, Garlanda C, Valsecchi MG, Rovelli A, D'Amico G.

Oncotarget. 2016 Dec 13;7(50):82123-82138. doi: 10.18632/oncotarget.13488.


Molecular Evolution of Human Coronavirus Genomes.

Forni D, Cagliani R, Clerici M, Sironi M.

Trends Microbiol. 2017 Jan;25(1):35-48. doi: 10.1016/j.tim.2016.09.001. Epub 2016 Oct 19. Review.


Assessment of DFT Functionals for QTAIM Topological Analysis of Halogen Bonds with Benzene.

Forni A, Pieraccini S, Franchini D, Sironi M.

J Phys Chem A. 2016 Nov 17;120(45):9071-9080. Epub 2016 Nov 7.


A 6-amino acid insertion/deletion polymorphism in the mucin domain of TIM-1 confers protections against HIV-1 infection.

Biasin M, Sironi M, Saulle I, Pontremoli C, Garziano M, Cagliani R, Trabattoni D, Lo Caputo S, Vichi F, Mazzotta F, Forni D, Riva S, Aguilar-Jimenez W, Cedeño S, Sanchez J, Brander C, Zapata W, Rugeles MT, Clerici M.

Microbes Infect. 2017 Jan;19(1):69-74. doi: 10.1016/j.micinf.2016.09.005. Epub 2016 Sep 18.


Nonstructural Proteins Are Preferential Positive Selection Targets in Zika Virus and Related Flaviviruses.

Sironi M, Forni D, Clerici M, Cagliani R.

PLoS Negl Trop Dis. 2016 Sep 2;10(9):e0004978. doi: 10.1371/journal.pntd.0004978. eCollection 2016 Sep.


Positive Selection Drives Evolution at the Host-Filovirus Interaction Surface.

Pontremoli C, Forni D, Cagliani R, Filippi G, De Gioia L, Pozzoli U, Clerici M, Sironi M.

Mol Biol Evol. 2016 Nov;33(11):2836-2847. Epub 2016 Aug 10.


Functional TRAIL receptors in monocytes and tumor-associated macrophages: A possible targeting pathway in the tumor microenvironment.

Liguori M, Buracchi C, Pasqualini F, Bergomas F, Pesce S, Sironi M, Grizzi F, Mantovani A, Belgiovine C, Allavena P.

Oncotarget. 2016 Jul 5;7(27):41662-41676. doi: 10.18632/oncotarget.9340.


4-(1,2-diarylbut-1-en-1-yl)isobutyranilide derivatives as inhibitors of topoisomerase II.

Christodoulou MS, Zarate M, Ricci F, Damia G, Pieraccini S, Dapiaggi F, Sironi M, Lo Presti L, García-Argáez AN, Dalla Via L, Passarella D.

Eur J Med Chem. 2016 Aug 8;118:79-89. doi: 10.1016/j.ejmech.2016.03.090. Epub 2016 Apr 11.


Post-mortem findings in southern right whales Eubalaena australis at Península Valdés, Argentina, 2003-2012.

McAloose D, Rago MV, Di Martino M, Chirife A, Olson SH, Beltramino L, Pozzi LM, Musmeci L, La Sala L, Mohamed N, Sala JE, Bandieri L, Andrejuk J, Tomaszewicz A, Seimon T, Sironi M, Samartino LE, Rowntree V, Uhart MM.

Dis Aquat Organ. 2016 Apr 12;119(1):17-36. doi: 10.3354/dao02986.


Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation.

Bonacina F, Barbieri SS, Cutuli L, Amadio P, Doni A, Sironi M, Tartari S, Mantovani A, Bottazzi B, Garlanda C, Tremoli E, Catapano AL, Norata GD.

Biochim Biophys Acta. 2016 Jun;1862(6):1182-90. doi: 10.1016/j.bbadis.2016.03.007. Epub 2016 Mar 11.


The evolutionary history of genes involved in spoken and written language: beyond FOXP2.

Mozzi A, Forni D, Clerici M, Pozzoli U, Mascheretti S, Guerini FR, Riva S, Bresolin N, Cagliani R, Sironi M.

Sci Rep. 2016 Feb 25;6:22157. doi: 10.1038/srep22157.


The mammalian complement system as an epitome of host-pathogen genetic conflicts.

Cagliani R, Forni D, Filippi G, Mozzi A, De Gioia L, Pontremoli C, Pozzoli U, Bresolin N, Clerici M, Sironi M.

Mol Ecol. 2016 Mar;25(6):1324-39. doi: 10.1111/mec.13558.


Extensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C Betacoronaviruses.

Forni D, Cagliani R, Mozzi A, Pozzoli U, Al-Daghri N, Clerici M, Sironi M.

J Virol. 2016 Jan 20;90(7):3627-39. doi: 10.1128/JVI.02988-15.


Correction: Increased Wounding of Southern Right Whale (Eubalaena australis) Calves by Kelp Gulls (Larus dominicanus) at Península Valdés, Argentina.

Marón CF, Beltramino L, Di Martino M, Chirife A, Seger J, Uhart M, Sironi M, Rowntree VJ.

PLoS One. 2015 Nov 10;10(11):e0142969. doi: 10.1371/journal.pone.0142969. eCollection 2015. No abstract available.


Determining multiallelic complex copy number and sequence variation from high coverage exome sequencing data.

Forni D, Martin D, Abujaber R, Sharp AJ, Sironi M, Hollox EJ.

BMC Genomics. 2015 Nov 2;16:891. doi: 10.1186/s12864-015-2123-y.


Increased Wounding of Southern Right Whale (Eubalaena australis) Calves by Kelp Gulls (Larus dominicanus) at Península Valdés, Argentina.

Marón CF, Beltramino L, Di Martino M, Chirife A, Seger J, Uhart M, Sironi M, Rowntree VJ.

PLoS One. 2015 Oct 21;10(10):e0139291. doi: 10.1371/journal.pone.0139291. eCollection 2015. Erratum in: PLoS One. 2015;10(11):e0142969.


The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses.

Forni D, Filippi G, Cagliani R, De Gioia L, Pozzoli U, Al-Daghri N, Clerici M, Sironi M.

Sci Rep. 2015 Sep 25;5:14480. doi: 10.1038/srep14480.


Variants in the CYP7B1 gene region do not affect natural resistance to HIV-1 infection.

Sironi M, Biasin M, Pontremoli C, Cagliani R, Saulle I, Trabattoni D, Vichi F, Lo Caputo S, Mazzotta F, Aguilar-Jimenez W, Rugeles MT, Cedeno S, Sanchez J, Brander C, Clerici M.

Retrovirology. 2015 Sep 24;12:80. doi: 10.1186/s12977-015-0206-0.


Solid Variant of Adenoid Cystic Carcinoma of the Breast: A Case Series With Proposal of a New Grading System.

Foschini MP, Rizzo A, De Leo A, Laurino L, Sironi M, Rucco V.

Int J Surg Pathol. 2016 Apr;24(2):97-102. doi: 10.1177/1066896915606973. Epub 2015 Sep 16.


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