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Items: 20


Discovery of autophagy inhibitors with antiproliferative activity in lung and pancreatic cancer cells.

Nordstrøm LU, Sironi J, Aranda E, Maisonet J, Perez-Soler R, Wu P, Schwartz EL.

ACS Med Chem Lett. 2015 Jan 8;6(2):134-9. doi: 10.1021/ml500348p. eCollection 2015 Feb 12.


Cytosolic carboxypeptidase 5 removes α- and γ-linked glutamates from tubulin.

Berezniuk I, Lyons PJ, Sironi JJ, Xiao H, Setou M, Angeletti RH, Ikegami K, Fricker LD.

J Biol Chem. 2013 Oct 18;288(42):30445-53. doi: 10.1074/jbc.M113.497917. Epub 2013 Sep 10.


Quantitative peptidomics of Purkinje cell degeneration mice.

Berezniuk I, Sironi JJ, Wardman J, Pasek RC, Berbari NF, Yoder BK, Fricker LD.

PLoS One. 2013 Apr 8;8(4):e60981. doi: 10.1371/journal.pone.0060981. Print 2013.


The autophagy inhibitor chloroquine overcomes the innate resistance of wild-type EGFR non-small-cell lung cancer cells to erlotinib.

Zou Y, Ling YH, Sironi J, Schwartz EL, Perez-Soler R, Piperdi B.

J Thorac Oncol. 2013 Jun;8(6):693-702. doi: 10.1097/JTO.0b013e31828c7210.


Alterations of the intracellular peptidome in response to the proteasome inhibitor bortezomib.

Gelman JS, Sironi J, Berezniuk I, Dasgupta S, Castro LM, Gozzo FC, Ferro ES, Fricker LD.

PLoS One. 2013;8(1):e53263. doi: 10.1371/journal.pone.0053263. Epub 2013 Jan 7.


Cytosolic carboxypeptidase 1 is involved in processing α- and β-tubulin.

Berezniuk I, Vu HT, Lyons PJ, Sironi JJ, Xiao H, Burd B, Setou M, Angeletti RH, Ikegami K, Fricker LD.

J Biol Chem. 2012 Feb 24;287(9):6503-17. doi: 10.1074/jbc.M111.309138. Epub 2011 Dec 14.


Peptidomic analysis of human cell lines.

Gelman JS, Sironi J, Castro LM, Ferro ES, Fricker LD.

J Proteome Res. 2011 Apr 1;10(4):1583-92. doi: 10.1021/pr100952f. Epub 2011 Feb 17.


Both gene amplification and allelic loss occur at 14q13.3 in lung cancer.

Harris T, Pan Q, Sironi J, Lutz D, Tian J, Sapkar J, Perez-Soler R, Keller S, Locker J.

Clin Cancer Res. 2011 Feb 15;17(4):690-9. doi: 10.1158/1078-0432.CCR-10-1892. Epub 2010 Dec 10.


Hemopressins and other hemoglobin-derived peptides in mouse brain: comparison between brain, blood, and heart peptidome and regulation in Cpefat/fat mice.

Gelman JS, Sironi J, Castro LM, Ferro ES, Fricker LD.

J Neurochem. 2010 May;113(4):871-80. doi: 10.1111/j.1471-4159.2010.06653.x. Epub 2010 Feb 24.


CCP1/Nna1 functions in protein turnover in mouse brain: Implications for cell death in Purkinje cell degeneration mice.

Berezniuk I, Sironi J, Callaway MB, Castro LM, Hirata IY, Ferro ES, Fricker LD.

FASEB J. 2010 Jun;24(6):1813-23. doi: 10.1096/fj.09-147942. Epub 2010 Jan 8.


Analysis of intracellular substrates and products of thimet oligopeptidase in human embryonic kidney 293 cells.

Berti DA, Morano C, Russo LC, Castro LM, Cunha FM, Zhang X, Sironi J, Klitzke CF, Ferro ES, Fricker LD.

J Biol Chem. 2009 May 22;284(21):14105-16. doi: 10.1074/jbc.M807916200. Epub 2009 Mar 12.


Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis.

Yamamoto K, Nihrane A, Aglipay J, Sironi J, Arkin S, Lipton JM, Ouchi T, Liu JM.

Mol Med. 2008 Mar-Apr;14(3-4):167-74. doi: 10.2119/2007-00122.Yamamoto.


Loss of p53-regulatory protein IFI16 induces NBS1 leading to activation of p53-mediated checkpoint by phosphorylation of p53 SER37.

Tawara H, Fujiuchi N, Sironi J, Martin S, Aglipay J, Ouchi M, Taga M, Chen PL, Ouchi T.

Front Biosci. 2008 Jan 1;13:240-8.


STAT1-induced apoptosis is mediated by caspases 2, 3, and 7.

Sironi JJ, Ouchi T.

J Biol Chem. 2004 Feb 6;279(6):4066-74. Epub 2003 Nov 17.


Association of tubulin carboxypeptidase with microtubules in living cells.

Contin MA, Sironi JJ, Barra HS, Arce CA.

Biochem J. 1999 Apr 15;339 ( Pt 2):463-71.


Ser-262 in human recombinant tau protein is a markedly more favorable site for phosphorylation by CaMKII than PKA or PhK.

Sironi JJ, Yen SH, Gondal JA, Wu Q, Grundke-Iqbal I, Iqbal K.

FEBS Lett. 1998 Oct 9;436(3):471-5.


Isolation of alpha and beta brain tubulin subunits after alkaline treatment of the protein.

Beltramo DM, Nuñez Fernandez M, Alonso AD, Sironi JJ, Barra HS.

Neurochem Res. 1997 Apr;22(4):385-9.


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