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Cardiovascular Risk in Essential Thrombocythemia and Polycythemia Vera: Thrombotic Risk and Survival.

Accurso V, Santoro M, Mancuso S, Contrino AD, Casimiro P, Sardo M, Raso S, Di Piazza F, Perez A, Bono M, Russo A, Siragusa S.

Mediterr J Hematol Infect Dis. 2020 Jan 1;12(1):e2020008. doi: 10.4084/MJHID.2020.008. eCollection 2020.


Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study.

Accurso V, Santoro M, Raso S, Contrino AD, Casimiro P, Piazza FD, Perez A, Russo A, Siragusa S.

Hematol Rep. 2019 Dec 4;11(4):8281. doi: 10.4081/hr.2019.8281. eCollection 2019 Nov 29.


Status of Recombinant Factor VIII Concentrate Treatment for Hemophilia a in Italy: Characteristics and Clinical Benefits.

Schiavoni M, Napolitano M, Giuffrida G, Coluccia A, Siragusa S, Calafiore V, Lassandro G, Giordano P.

Front Med (Lausanne). 2019 Dec 3;6:261. doi: 10.3389/fmed.2019.00261. eCollection 2019. Review.


Management of Ponatinib in Patients with Chronic Myeloid Leukemia with Cardiovascular Risk Factors.

Santoro M, Accurso V, Mancuso S, Contrino AD, Sardo M, Novo G, Di Piazza F, Perez A, Russo A, Siragusa S.

Chemotherapy. 2019 Dec 11:1-5. doi: 10.1159/000504664. [Epub ahead of print]


Can we compare haemophilia carriers with clotting factor deficiency to male patients with mild haemophilia?

Raso S, Lambert C, Boban A, Napolitano M, Siragusa S, Hermans C.

Haemophilia. 2019 Dec 9. doi: 10.1111/hae.13891. [Epub ahead of print]


Detection and Clinical Implications of a Novel BCR-ABL1 E12A2 Insertion/Deletion in a CML Patient Expressing the E13A2 Isoform.

Stella S, Massimino M, Tirrò E, Vitale SR, Accurso V, Puma A, Pennisi MS, DI Gregorio S, Romano C, DI Raimondo F, Siragusa S, Manzella L.

Anticancer Res. 2019 Dec;39(12):6965-6971. doi: 10.21873/anticanres.13918.


Peripheral circulating cells with paroxysmal nocturnal haemoglobinuria phenotype after a first episode of cerebral sinus vein thrombosis: Results from a multicentre cross-sectional study.

Napolitano M, Santoro RC, Nicolosi D, Calafiore V, Triolo A, Raso S, Parrinello L, Rizzo G, Sottilotta G, Siragusa S, Giuffrida G.

Thromb Res. 2020 Jan;185:85-87. doi: 10.1016/j.thromres.2019.11.025. Epub 2019 Nov 21. No abstract available.


Buffy coat-derived platelets cryopreserved using a new method: Results from a pivotal clinical trial on thrombocytopenic patients with acute leukaemia.

Napolitano M, Mancuso S, Raso S, LoCoco L, Arfò PS, De Francisci G, Dieli F, Caccamo N, Reina A, Dolce A, Agliastro R, Siragusa S.

Transfus Apher Sci. 2019 Dec;58(6):102666. doi: 10.1016/j.transci.2019.10.008. Epub 2019 Nov 5.


Immune tolerance induction with moroctocog-alpha (Refacto/Refacto AF) in a population of Italian haemophilia A patients with high-titre inhibitors: Data from REF.IT Registry.

Zanon E, Pasca S, Pollio B, Santagostino E, Linari S, Tagliaferri A, Santoro C, Rocino A, Marino R, Aru B, Borchiellini A, Siragusa S, Coppola A.

Haemophilia. 2019 Nov;25(6):1003-1010. doi: 10.1111/hae.13859. Epub 2019 Oct 11.


Comparison between thrombotic risk scores in essential thrombocythemia and survival implications.

Santoro M, Accurso V, Mancuso S, Carlisi M, Raso S, Tarantino G, Di Piazza F, Perez A, Russo A, Siragusa S.

Hematol Oncol. 2019 Oct;37(4):434-437. doi: 10.1002/hon.2670. Epub 2019 Sep 6.


BCR-ABL1 Doubling-Times and Halving-Times May Predict CML Response to Tyrosine Kinase Inhibitors.

Pennisi MS, Stella S, Vitale SR, Puma A, Di Gregorio S, Romano C, Tirrò E, Massimino M, Antolino A, Siragusa S, Mannina D, Impera S, Musolino C, Mineo G, Martino B, Zammit V, Di Raimondo F, Manzella L, Stagno F, Vigneri P.

Front Oncol. 2019 Aug 13;9:764. doi: 10.3389/fonc.2019.00764. eCollection 2019.


Haemorheological profile in congenital afibrinogenemia and in congenital dysfibrinogenemia: A clinical case report.

Caimi G, Raso S, Napolitano M, Hopps E, Lo Presti R, Siragusa S.

Clin Hemorheol Microcirc. 2019;73(4):523-530. doi: 10.3233/CH-180542.


Italian survey on clinical practice in myeloproliferative neoplasms. A GIMEMA Myeloproliferative Neoplasms Working Party initiative.

Loscocco GG, Mannelli F, Guglielmelli P, Paoli C, Marone I, Cucci R, Coltro G, Sordi B, Albano F, Breccia M, De Stefano V, Finazzi G, Iurlo A, Martino B, Palandri F, Passamonti F, Siragusa S, Mannelli L, Fantoni D, Fazi P, Amadori S, Vignetti M, Barbui T, Vannucchi AM.

Am J Hematol. 2019 Jun 9. doi: 10.1002/ajh.25555. [Epub ahead of print] No abstract available.


Paroxysmal nocturnal hemoglobinuria-like phenotype and thrombotic risk in several clinical disorders.

Carlisi M, Mancuso S, Caimi G, Siragusa S.

Panminerva Med. 2019 May 29. doi: 10.23736/S0031-0808.19.03612-7. [Epub ahead of print] No abstract available.


Age at diagnosis is an important prognostic factor in Philadelphia-negative Myeloproliferative Neoplasms.

Accurso V, Santoro M, Siragusa S.

Eur J Haematol. 2019 Aug;103(2):140-141. doi: 10.1111/ejh.13266. Epub 2019 Jun 13. No abstract available.


Efficacy of ruxolitinib retreatment in a patient with high-risk myelofibrosis using the international prognostic scoring system.

Accurso V, Santoro M, Mancuso S, Napolitano M, Di Piazza F, Russo A, Siragusa SM.

Drugs Context. 2019 Mar 4;8:212569. doi: 10.7573/dic.212569. eCollection 2019. No abstract available.


Bone marrow characteristics predict outcome in a multicenter cohort of primary immune thrombocytopenia patients treated with thrombopoietin analogs.

Fattizzo B, Pasquale R, Carpenedo M, Cantoni S, Auteri G, Gramegna D, D'Adda M, Napolitano M, Consonni D, Ruggeri M, Siragusa S, Rossi G, Vianelli N, Barcellini W.

Haematologica. 2019 Oct;104(10):e470-e473. doi: 10.3324/haematol.2019.216804. Epub 2019 Mar 7. No abstract available.


Low dose of aPCC after the initial treatment in acquired haemophilia A is useful to reduce bleeding relapses: Data from the FAIR registry.

Zanon E, Pasca S, Siragusa S, Napolitano M, Santoro C, Mameli L, Rocino A; FAIR Study Group.

Thromb Res. 2019 Feb;174:24-26. doi: 10.1016/j.thromres.2018.12.006. Epub 2018 Dec 6.


Platelet cut-off for anticoagulant therapy in thrombocytopenic patients with blood cancer and venous thromboembolism: an expert consensus.

Napolitano M, Saccullo G, Marietta M, Carpenedo M, Castaman G, Cerchiara E, Chistolini A, Contino L, De Stefano V, Falanga A, Federici AB, Rossi E, Santoro R, Siragusa S; Gruppo Italiano Malattie EMatologiche dell’Adulto (GIMEMA) Working Party on Thrombosis and Hemostasis; Gruppo Italiano Malattie Ematologiche dell’Adulto (GIMEMA) Working Party on Thrombosis and Haemostasis (see Appendix 1), De Stefano V, Falanga A, Tosetto A, Avvisati G, Carpenedo M, Federici AB, Marietta M, Napolitano M, Rossi E, Santoro C, Castaman G, Cerchiara E, Chistolini A, Contino L, Mazzucconi MG, Nichele I, Russo L, Santi R, Santoro RC, Siragusa S, Tagariello G.

Blood Transfus. 2019 May;17(3):171-180. doi: 10.2450/2018.0143-18. Epub 2018 Oct 24. Review.


Immunosenescence and lymphomagenesis.

Mancuso S, Carlisi M, Santoro M, Napolitano M, Raso S, Siragusa S.

Immun Ageing. 2018 Sep 21;15:22. doi: 10.1186/s12979-018-0130-y. eCollection 2018. Review.


Wholemeal wheat flours drive the microbiome and functional features of wheat sourdoughs.

De Angelis M, Minervini F, Siragusa S, Rizzello CG, Gobbetti M.

Int J Food Microbiol. 2019 Aug 2;302:35-46. doi: 10.1016/j.ijfoodmicro.2018.08.009. Epub 2018 Aug 10.


Buffy coat-derived platelets cryopreserved using a new method: Results from in vitro studies.

Napolitano M, Mancuso S, Lo Coco L, Arfò PS, Raso S, De Francisci G, Dieli F, Caccamo N, Reina A, Dolce A, Agliastro R, Siragusa S.

Transfus Apher Sci. 2018 Aug;57(4):578-581. doi: 10.1016/j.transci.2018.07.020. Epub 2018 Aug 1.


Paroxysmal nocturnal hemoglobinuria: When delay in diagnosis and long therapy occurs.

Mancuso S, Sucato G, Carlisi M, Santoro M, Tarantino G, Iannitto E, Napolitano M, Siragusa S.

Hematol Rep. 2018 Mar 29;10(1):7523. doi: 10.4081/hr.2018.7523. eCollection 2018 Mar 2.


Red blood cell deformability in multiple myeloma1.

Caimi G, Carlisi M, Montana M, Gallà E, Hopps E, Lo Presti R, Siragusa S.

Clin Hemorheol Microcirc. 2018;69(1-2):233-238. doi: 10.3233/CH-189121.


Incidence of venous thromboembolism and use of anticoagulation in hematological malignancies: Critical review of the literature.

Annibali O, Napolitano M, Avvisati G, Siragusa S.

Crit Rev Oncol Hematol. 2018 Apr;124:41-50. doi: 10.1016/j.critrevonc.2018.02.003. Epub 2018 Feb 8. Review.


Activated prothrombin complex concentrate (FEIBA® ) in acquired haemophilia A: a large multicentre Italian study - the FAIR Registry.

Zanon E, Pasca S, Santoro C, Gamba G, Siragusa SM, Rocino A, Cantori I, Federici AB, Mameli L, Giuffrida G, Falanga A, Lodigiani C, Santoro RC, Milan M, Ambaglio C, Napolitano M, Mazzucconi MG.

Br J Haematol. 2019 Mar;184(5):853-855. doi: 10.1111/bjh.15175. Epub 2018 Mar 12. No abstract available.


Lymphomas and thyroid: Bridging the gap.

Mancuso S, Carlisi M, Napolitano M, Siragusa S.

Hematol Oncol. 2018 Feb 27. doi: 10.1002/hon.2504. [Epub ahead of print] Review.


Coronary artery stenosis treatment in aging patients with inherited Factor VII deficiency: Where do we stand?

Napolitano M, Siragusa S.

Transfus Apher Sci. 2017 Dec;56(6):867-869. doi: 10.1016/j.transci.2017.10.005.


Cardio-oncology in multiple myeloma: is it time for a specific focus?

Mancuso S, Carlisi M, Sarocchi M, Napolitano M, Siragusa S.

Leuk Lymphoma. 2018 Jul;59(7):1764-1766. doi: 10.1080/10428194.2017.1393674. Epub 2017 Oct 31. No abstract available.



Siragusa S, Saadabadi A.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-.
2019 Oct 7.


Hemorheological parameters in Monoclonal Gammopathy of Undetermined Significance (MGUS).

Caimi G, Hopps E, Carlisi M, Montana M, Gallà E, Lo Presti R, Siragusa S.

Clin Hemorheol Microcirc. 2018;68(1):51-59. doi: 10.3233/CH-170289.


Erythrocyte deformability and hemorheological profile in multiple myeloma.

Caimi G, Carlisi M, Montana M, Gallà E, Lo Presti R, Hopps E, Siragusa S.

Clin Hemorheol Microcirc. 2018;68(1):25-34. doi: 10.3233/CH-170267.


Late onset of unilateral optic disk edema secondary to treatment with imatinib mesylate.

Napolitano M, Santoro M, Mancuso S, Carlisi M, Raso S, Tarantino G, Accurso V, Siragusa S.

Clin Case Rep. 2017 Aug 15;5(10):1573-1575. doi: 10.1002/ccr3.1137. eCollection 2017 Oct.


Acquired haemophilia in cancer: A systematic and critical literature review.

Napolitano M, Siragusa S, Mancuso S, Kessler CM.

Haemophilia. 2018 Jan;24(1):43-56. doi: 10.1111/hae.13355. Epub 2017 Sep 27. Review.


High BCR-ABL/GUSIS Levels at Diagnosis of Chronic Phase CML Are Associated with Unfavorable Responses to Standard-Dose Imatinib.

Vigneri P, Stagno F, Stella S, Cupri A, Forte S, Massimino M, Antolino A, Siragusa S, Mannina D, Impera SS, Musolino C, Malato A, Mineo G, Tomaselli C, Murgano P, Musso M, Morabito F, Molica S, Martino B, Manzella L, Müller MC, Hochhaus A, Raimondo FD.

Clin Cancer Res. 2017 Dec 1;23(23):7189-7198. doi: 10.1158/1078-0432.CCR-17-0962. Epub 2017 Sep 19.


Prolonged anticoagulant treatment in patients with cancer: Where do we stand?

Napolitano M, Siragusa S.

Thromb Res. 2017 Oct;158:152-153. doi: 10.1016/j.thromres.2017.09.009. Epub 2017 Sep 8. No abstract available.


Clinical course of patients with symptomatic isolated superficial vein thrombosis: the ICARO follow-up study.

Barco S, Pomero F, Di Minno MND, Tamborini Permunian E, Malato A, Pasca S, Barillari G, Fenoglio L, Siragusa S, Di Minno G, Ageno W, Dentali F.

J Thromb Haemost. 2017 Nov;15(11):2176-2183. doi: 10.1111/jth.13840. Epub 2017 Oct 19.


Factor VII Deficiency: Clinical Phenotype, Genotype and Therapy.

Napolitano M, Siragusa S, Mariani G.

J Clin Med. 2017 Mar 28;6(4). pii: E38. doi: 10.3390/jcm6040038. Review.


A population-based study of chronic myeloid leukemia patients treated with imatinib in first line.

Castagnetti F, Di Raimondo F, De Vivo A, Spitaleri A, Gugliotta G, Fabbiano F, Capodanno I, Mannina D, Salvucci M, Antolino A, Marasca R, Musso M, Crugnola M, Impera S, Trabacchi E, Musolino C, Cavazzini F, Mineo G, Tosi P, Tomaselli C, Rizzo M, Siragusa S, Fogli M, Ragionieri R, Zironi A, Soverini S, Martinelli G, Cavo M, Vigneri P, Stagno F, Rosti G, Baccarani M.

Am J Hematol. 2017 Jan;92(1):82-87. doi: 10.1002/ajh.24591. Epub 2016 Nov 18.


Abdominal aortic thrombosis secondary to reactive thrombocytosis in a patient with iron deficiency anemia.

Raso S, Napolitano M, Saccullo G, Siragusa S.

Ann Hematol. 2016 Aug;95(8):1389-90. doi: 10.1007/s00277-016-2715-x. Epub 2016 Jun 2. No abstract available.


Hematopoietic peripheral circulating blood stem cells as an independent marker of good transfusion management in patients with β-thalassemia: results from a preliminary study.

Napolitano M, Gerardi C, Di Lucia A, Accardo PA, Rizzuto L, Ferraro M, Siragusa S, Buscemi F.

Transfusion. 2016 Apr;56(4):827-30. doi: 10.1111/trf.13452. Epub 2016 Jan 22.


The impact of deep vein thrombosis in critically ill patients: a meta-analysis of major clinical outcomes.

Malato A, Dentali F, Siragusa S, Fabbiano F, Kagoma Y, Boddi M, Gensini GF, Peris A, Crowther M, Napolitano M.

Blood Transfus. 2015 Oct;13(4):559-68. doi: 10.2450/2015.0277-14. Review.


A clinical score to rule out the concomitant presence of deep vein thrombosis in patients presenting with superficial vein thrombosis: The ICARO study.

Pomero F, Di Minno MN, Tamburini Premunian E, Malato A, Pasca S, Barillari G, Fenoglio L, Siragusa S, Di Minno G, Ageno W, Dentali F.

Thromb Res. 2015 Nov;136(5):938-42. doi: 10.1016/j.thromres.2015.09.010. Epub 2015 Sep 11.


Management of venous thromboembolism in patients with acute leukemia at high bleeding risk: a multi-center study.

Napolitano M, Valore L, Malato A, Saccullo G, Vetro C, Mitra ME, Fabbiano F, Mannina D, Casuccio A, Lucchesi A, Del Principe MI, Candoni A, Di Raimondo F, Siragusa S.

Leuk Lymphoma. 2016;57(1):116-9. doi: 10.3109/10428194.2015.1046864. Epub 2015 May 25.


Reply to e.g. Urrego et Al.

Napolitano M, Siragusa S.

J Clin Oncol. 2015 May 20;33(15):1713-4. doi: 10.1200/JCO.2015.60.8414. Epub 2015 Apr 13. No abstract available.


Comparative proteomic analysis of biofilm and planktonic cells of Lactobacillus plantarum DB200.

De Angelis M, Siragusa S, Campanella D, Di Cagno R, Gobbetti M.

Proteomics. 2015 Jul;15(13):2244-57. doi: 10.1002/pmic.201400363. Epub 2015 Apr 10.


Optimal duration of low molecular weight heparin for the treatment of cancer-related deep vein thrombosis: the Cancer-DACUS Study.

Napolitano M, Saccullo G, Malato A, Sprini D, Ageno W, Imberti D, Mascheroni D, Bucherini E, Gallucci P, D'Alessio A, Prantera T, Spadaro P, Rotondo S, Di Micco P, Oriana V, Urbano O, Recchia F, Ghirarduzzi A, Lo Coco L, Mancuso S, Casuccio A, Rini GB, Siragusa S.

J Clin Oncol. 2014 Nov 10;32(32):3607-12. doi: 10.1200/JCO.2013.51.7433. Epub 2014 Sep 29.


Absolute lymphocyte count is unrelated to overall survival in newly diagnosed elderly patients with multiple myeloma treated with immunomodulatory drugs.

Napolitano M, Saccullo G, Bono R, Branca A, Cangialosi C, Mancuso S, Raso S, Quintini G, Lipari MG, Fabbiano F, Specchia G, Dolce A, Di Raimondo F, Siragusa S.

Leuk Lymphoma. 2015 May;56(5):1507-9. doi: 10.3109/10428194.2014.955021. Epub 2014 Oct 7. No abstract available.


Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria phenotype in patients with splanchnic vein thrombosis.

Ageno W, Dentali F, De Stefano V, Barco S, Lerede T, Bazzan M, Piana A, Santoro R, Duce R, Poli D, Martinelli I, Siragusa S, Barillari G, Cattaneo M, Vidili G, Carpenedo M, Rancan E, Giaretta I, Tosetto A.

Thromb Res. 2014 Jun;133(6):1052-5. doi: 10.1016/j.thromres.2014.03.044. Epub 2014 Apr 1.


Salivary microbiota and metabolome associated with celiac disease.

Francavilla R, Ercolini D, Piccolo M, Vannini L, Siragusa S, De Filippis F, De Pasquale I, Di Cagno R, Di Toma M, Gozzi G, Serrazanetti DI, De Angelis M, Gobbetti M.

Appl Environ Microbiol. 2014 Jun;80(11):3416-25. doi: 10.1128/AEM.00362-14. Epub 2014 Mar 21.

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