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Items: 37

1.

The Transcription Factor PLZF Is Necessary for the Development and Function of Mouse Basophils.

Zhang S, Vieth JA, Krzyzanowska A, Henry EK, Denzin LK, Siracusa MC, Sant'Angelo DB.

J Immunol. 2019 Sep 1;203(5):1230-1241. doi: 10.4049/jimmunol.1900068. Epub 2019 Jul 31.

PMID:
31366712
2.

Contributions of innate lymphocytes to allergic responses.

Inclan-Rico JM, Ponessa JJ, Siracusa MC.

Curr Opin Allergy Clin Immunol. 2019 Apr;19(2):175-184. doi: 10.1097/ACI.0000000000000515.

PMID:
30672750
3.

Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44.

Shan M, Carrillo J, Yeste A, Gutzeit C, Segura-Garzón D, Walland AC, Pybus M, Grasset EK, Yeiser JR, Matthews DB, van de Veen W, Comerma L, He B, Boonpiyathad T, Lee H, Blanco J, Osborne LC, Siracusa MC, Akdis M, Artis D, Mehandru S, Sampson HA, Berin MC, Chen K, Cerutti A.

Immunity. 2018 Oct 16;49(4):709-724.e8. doi: 10.1016/j.immuni.2018.08.013. Epub 2018 Oct 2.

PMID:
30291028
4.

First Responders: Innate Immunity to Helminths.

Inclan-Rico JM, Siracusa MC.

Trends Parasitol. 2018 Oct;34(10):861-880. doi: 10.1016/j.pt.2018.08.007. Epub 2018 Aug 31. Review.

PMID:
30177466
5.

Type 2 cytokine responses: regulating immunity to helminth parasites and allergic inflammation.

Henry EK, Inclan-Rico JM, Siracusa MC.

Curr Pharmacol Rep. 2017 Dec;3(6):346-359. doi: 10.1007/s40495-017-0114-1. Epub 2017 Oct 19.

6.

Skin-derived TSLP systemically expands regulatory T cells.

Leichner TM, Satake A, Harrison VS, Tanaka Y, Archambault AS, Kim BS, Siracusa MC, Leonard WJ, Naji A, Wu GF, Artis D, Kambayashi T.

J Autoimmun. 2017 May;79:39-52. doi: 10.1016/j.jaut.2017.01.003. Epub 2017 Jan 23.

7.

Carbonic anhydrase enzymes regulate mast cell-mediated inflammation.

Henry EK, Sy CB, Inclan-Rico JM, Espinosa V, Ghanny SS, Dwyer DF, Soteropoulos P, Rivera A, Siracusa MC.

J Exp Med. 2016 Aug 22;213(9):1663-73. doi: 10.1084/jem.20151739. Epub 2016 Aug 15.

8.

The Therapeutic Potential of Targeting Cytokine Alarmins to Treat Allergic Airway Inflammation.

Sy CB, Siracusa MC.

Front Physiol. 2016 Jun 14;7:214. doi: 10.3389/fphys.2016.00214. eCollection 2016. Review.

9.

Innate cell communication kick-starts pathogen-specific immunity.

Rivera A, Siracusa MC, Yap GS, Gause WC.

Nat Immunol. 2016 Apr;17(4):356-63. doi: 10.1038/ni.3375. Review.

10.

IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing.

Rak GD, Osborne LC, Siracusa MC, Kim BS, Wang K, Bayat A, Artis D, Volk SW.

J Invest Dermatol. 2016 Feb;136(2):487-496. doi: 10.1038/JID.2015.406.

11.

Epithelial-intrinsic IKKα expression regulates group 3 innate lymphoid cell responses and antibacterial immunity.

Giacomin PR, Moy RH, Noti M, Osborne LC, Siracusa MC, Alenghat T, Liu B, McCorkell KA, Troy AE, Rak GD, Hu Y, May MJ, Ma HL, Fouser LA, Sonnenberg GF, Artis D.

J Exp Med. 2015 Sep 21;212(10):1513-28. doi: 10.1084/jem.20141831. Epub 2015 Sep 14.

12.

Functional diversification and specialization of cytosolic 70-kDa heat shock proteins.

McCallister C, Siracusa MC, Shirazi F, Chalkia D, Nikolaidis N.

Sci Rep. 2015 Mar 20;5:9363. doi: 10.1038/srep09363.

13.

In situ hematopoiesis: a regulator of TH2 cytokine-mediated immunity and inflammation at mucosal surfaces.

Hui CC, McNagny KM, Denburg JA, Siracusa MC.

Mucosal Immunol. 2015 Jul;8(4):701-11. doi: 10.1038/mi.2015.17. Epub 2015 Mar 18. Review.

PMID:
25783967
14.

Basophils promote innate lymphoid cell responses in inflamed skin.

Kim BS, Wang K, Siracusa MC, Saenz SA, Brestoff JR, Monticelli LA, Noti M, Tait Wojno ED, Fung TC, Kubo M, Artis D.

J Immunol. 2014 Oct 1;193(7):3717-25. doi: 10.4049/jimmunol.1401307. Epub 2014 Aug 25.

15.

Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.

Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K, Bailey AG, Laughlin AL, Boucher JL, Wherry EJ, Bushman FD, Allen JE, Virgin HW, Artis D.

Science. 2014 Aug 1;345(6196):578-82. doi: 10.1126/science.1256942. Epub 2014 Jul 17.

16.

Immune responses in macaques to a prototype recombinant adenovirus live oral human papillomavirus 16 vaccine.

Berg MG, Adams RJ, Gambhira R, Siracusa MC, Scott AL, Roden RB, Ketner G.

Clin Vaccine Immunol. 2014 Sep;21(9):1224-31. doi: 10.1128/CVI.00197-14. Epub 2014 Jul 2.

17.

Hybridization capture reveals evolution and conservation across the entire Koala retrovirus genome.

Tsangaras K, Siracusa MC, Nikolaidis N, Ishida Y, Cui P, Vielgrader H, Helgen KM, Roca AL, Greenwood AD.

PLoS One. 2014 Apr 21;9(4):e95633. doi: 10.1371/journal.pone.0095633. eCollection 2014.

18.

Omalizumab therapy is associated with reduced circulating basophil populations in asthmatic children.

Hill DA, Siracusa MC, Ruymann KR, Tait Wojno ED, Artis D, Spergel JM.

Allergy. 2014 May;69(5):674-7. doi: 10.1111/all.12375. Epub 2014 Feb 24.

19.

Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis.

Noti M, Kim BS, Siracusa MC, Rak GD, Kubo M, Moghaddam AE, Sattentau QA, Comeau MR, Spergel JM, Artis D.

J Allergy Clin Immunol. 2014 May;133(5):1390-9, 1399.e1-6. doi: 10.1016/j.jaci.2014.01.021. Epub 2014 Feb 20.

20.

Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.

Siracusa MC, Saenz SA, Wojno ED, Kim BS, Osborne LC, Ziegler CG, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM, Hakonarson H, Cianferoni A, Wang ML, Spergel JM, Comeau MR, Artis D.

Immunity. 2013 Dec 12;39(6):1158-70. doi: 10.1016/j.immuni.2013.09.016.

21.

Basophils and allergic inflammation.

Siracusa MC, Kim BS, Spergel JM, Artis D.

J Allergy Clin Immunol. 2013 Oct;132(4):789-801; quiz 788. doi: 10.1016/j.jaci.2013.07.046. Review.

22.

IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells.

Saenz SA, Siracusa MC, Monticelli LA, Ziegler CG, Kim BS, Brestoff JR, Peterson LW, Wherry EJ, Goldrath AW, Bhandoola A, Artis D.

J Exp Med. 2013 Aug 26;210(9):1823-37. doi: 10.1084/jem.20122332. Epub 2013 Aug 19.

23.

Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.

Noti M, Wojno ED, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA, Chikwava KR, Moghaddam AE, Sattentau QJ, Alex A, Zhou C, Yearley JH, Menard-Katcher P, Kubo M, Obata-Ninomiya K, Karasuyama H, Comeau MR, Brown-Whitehorn T, de Waal Malefyt R, Sleiman PM, Hakonarson H, Cianferoni A, Falk GW, Wang ML, Spergel JM, Artis D.

Nat Med. 2013 Aug;19(8):1005-13. doi: 10.1038/nm.3281. Epub 2013 Jul 21.

24.

TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation.

Kim BS, Siracusa MC, Saenz SA, Noti M, Monticelli LA, Sonnenberg GF, Hepworth MR, Van Voorhees AS, Comeau MR, Artis D.

Sci Transl Med. 2013 Jan 30;5(170):170ra16. doi: 10.1126/scitranslmed.3005374.

25.

Thymic stromal lymphopoietin-dependent basophils promote Th2 cytokine responses following intestinal helminth infection.

Giacomin PR, Siracusa MC, Walsh KP, Grencis RK, Kubo M, Comeau MR, Artis D.

J Immunol. 2012 Nov 1;189(9):4371-8. doi: 10.4049/jimmunol.1200691. Epub 2012 Sep 28.

26.

Functional heterogeneity in the basophil cell lineage.

Siracusa MC, Wojno ED, Artis D.

Adv Immunol. 2012;115:141-59. doi: 10.1016/B978-0-12-394299-9.00005-9. Review.

27.

Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation.

Hill DA, Siracusa MC, Abt MC, Kim BS, Kobuley D, Kubo M, Kambayashi T, Larosa DF, Renner ED, Orange JS, Bushman FD, Artis D.

Nat Med. 2012 Mar 25;18(4):538-46. doi: 10.1038/nm.2657.

28.

TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation.

Siracusa MC, Saenz SA, Hill DA, Kim BS, Headley MB, Doering TA, Wherry EJ, Jessup HK, Siegel LA, Kambayashi T, Dudek EC, Kubo M, Cianferoni A, Spergel JM, Ziegler SF, Comeau MR, Artis D.

Nature. 2011 Aug 14;477(7363):229-33. doi: 10.1038/nature10329.

29.

New insights into basophil biology: initiators, regulators, and effectors of type 2 inflammation.

Siracusa MC, Comeau MR, Artis D.

Ann N Y Acad Sci. 2011 Jan;1217:166-77. doi: 10.1111/j.1749-6632.2010.05918.x. Review.

30.

IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses.

Saenz SA, Siracusa MC, Perrigoue JG, Spencer SP, Urban JF Jr, Tocker JE, Budelsky AL, Kleinschek MA, Kastelein RA, Kambayashi T, Bhandoola A, Artis D.

Nature. 2010 Apr 29;464(7293):1362-6. doi: 10.1038/nature08901. Epub 2010 Mar 3.

31.

New paradigms in basophil development, regulation and function.

Siracusa MC, Perrigoue JG, Comeau MR, Artis D.

Immunol Cell Biol. 2010 Mar-Apr;88(3):275-84. doi: 10.1038/icb.2010.1. Epub 2010 Feb 2. Review.

PMID:
20125116
32.

MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.

Perrigoue JG, Saenz SA, Siracusa MC, Allenspach EJ, Taylor BC, Giacomin PR, Nair MG, Du Y, Zaph C, van Rooijen N, Comeau MR, Pearce EJ, Laufer TM, Artis D.

Nat Immunol. 2009 Jul;10(7):697-705. doi: 10.1038/ni.1740. Epub 2009 May 24.

33.

Dynamics of lung macrophage activation in response to helminth infection.

Siracusa MC, Reece JJ, Urban JF Jr, Scott AL.

J Leukoc Biol. 2008 Dec;84(6):1422-33. doi: 10.1189/jlb.0308199. Epub 2008 Aug 21.

34.

Hookworm-induced persistent changes to the immunological environment of the lung.

Reece JJ, Siracusa MC, Southard TL, Brayton CF, Urban JF Jr, Scott AL.

Infect Immun. 2008 Aug;76(8):3511-24. doi: 10.1128/IAI.00192-08. Epub 2008 May 27.

35.

17beta-estradiol alters the activity of conventional and IFN-producing killer dendritic cells.

Siracusa MC, Overstreet MG, Housseau F, Scott AL, Klein SL.

J Immunol. 2008 Feb 1;180(3):1423-31.

36.
37.

Interleukin-4 produces a breakdown of tolerance in vivo with autoantibody formation and tissue damage.

Foote LC, Evans JW, Cifuni JM, Siracusa MC, Monteforte GM, McCole JL, D'Orazio CC, Hastings WD, Rothstein TL.

Autoimmunity. 2004 Dec;37(8):569-77.

PMID:
15763919

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