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Items: 33

1.

Heavy Chain Fibrillary Glomerulonephritis: A Case Report.

Nasr SH, Sirac C, Bridoux F, Javaugue V, Bender S, Rinsant A, Kaaki S, Pinault E, Dasari S, Alexander MP, Said SM, Hogan JJ, Dispenzieri A, Touchard G, McPhail ED, Leung N.

Am J Kidney Dis. 2019 Aug;74(2):276-280. doi: 10.1053/j.ajkd.2019.01.032. Epub 2019 Apr 5.

PMID:
30955945
2.

Randall-type monoclonal immunoglobulin deposition disease: novel insights from a nationwide cohort study.

Joly F, Cohen C, Javaugue V, Bender S, Belmouaz M, Arnulf B, Knebelmann B, Nouvier M, Audard V, Provot F, Gnemmi V, Nochy D, Goujon JM, Jaccard A, Touchard G, Fermand JP, Sirac C, Bridoux F.

Blood. 2019 Feb 7;133(6):576-587. doi: 10.1182/blood-2018-09-872028. Epub 2018 Dec 21.

PMID:
30578255
3.

Physiological and druggable skipping of immunoglobulin variable exons in plasma cells.

Ashi MO, Srour N, Lambert JM, Marchalot A, Martin O, Le Noir S, Pinaud E, Ayala MV, Sirac C, Saulière J, Moreaux J, Cogné M, Delpy L.

Cell Mol Immunol. 2018 Aug 20. doi: 10.1038/s41423-018-0160-6. [Epub ahead of print]

PMID:
30127381
4.

Comprehensive molecular characterization of a heavy chain deposition disease case.

Bender S, Ayala MV, Javaugue V, Bonaud A, Cogné M, Touchard G, Jaccard A, Bridoux F, Sirac C.

Haematologica. 2018 Nov;103(11):e557-e560. doi: 10.3324/haematol.2018.196113. Epub 2018 Jul 19. No abstract available.

5.

Animal models of monoclonal immunoglobulin-related renal diseases.

Sirac C, Herrera GA, Sanders PW, Batuman V, Bender S, Ayala MV, Javaugue V, Teng J, Turbat-Herrera EA, Cogné M, Touchard G, Leung N, Bridoux F.

Nat Rev Nephrol. 2018 Apr;14(4):246-264. doi: 10.1038/nrneph.2018.8. Epub 2018 Feb 19. Review.

PMID:
29456245
6.

[Classification and therapeutic management of monoclonal gammopathies of renal significance].

Javaugue V, Bouteau I, Sirac C, Quellard N, Diolez J, Colombo A, Desport E, Ecotière L, Goujon JM, Fermand JP, Touchard G, Jaccard A, Bridoux F.

Rev Med Interne. 2018 Mar;39(3):161-170. doi: 10.1016/j.revmed.2017.03.012. Epub 2017 Apr 27. Review. French.

PMID:
28457684
7.

Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management.

Bridoux F, Javaugue V, Bender S, Leroy F, Aucouturier P, Debiais-Delpech C, Goujon JM, Quellard N, Bonaud A, Clavel M, Trouillas P, Di Meo F, Gombert JM, Fermand JP, Jaccard A, Cogné M, Touchard G, Sirac C.

Kidney Int. 2017 Feb;91(2):423-434. doi: 10.1016/j.kint.2016.09.004. Epub 2016 Oct 20.

PMID:
27773425
8.

[Randall-type monoclonal immunoglobulin deposition disease: From diagnosis to treatment].

Cohen C, Javaugue V, Joly F, Arnulf B, Fermand JP, Jaccard A, Sirac C, Knebelmann B, Bridoux F, Touchard G.

Nephrol Ther. 2016 Jun;12(3):131-9. doi: 10.1016/j.nephro.2015.12.005. Epub 2016 Apr 21. Review. French.

PMID:
27117766
9.

A plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig production.

Srour N, Chemin G, Tinguely A, Ashi MO, Oruc Z, Péron S, Sirac C, Cogné M, Delpy L.

J Exp Med. 2016 Jan 11;213(1):109-22. doi: 10.1084/jem.20131511. Epub 2015 Dec 14.

10.

Impaired Lysosomal Function Underlies Monoclonal Light Chain-Associated Renal Fanconi Syndrome.

Luciani A, Sirac C, Terryn S, Javaugue V, Prange JA, Bender S, Bonaud A, Cogné M, Aucouturier P, Ronco P, Bridoux F, Devuyst O.

J Am Soc Nephrol. 2016 Jul;27(7):2049-61. doi: 10.1681/ASN.2015050581. Epub 2015 Nov 27.

11.

Efficient AID targeting of switch regions is not sufficient for optimal class switch recombination.

Bonaud A, Lechouane F, Le Noir S, Monestier O, Cogné M, Sirac C.

Nat Commun. 2015 Jul 6;6:7613. doi: 10.1038/ncomms8613.

PMID:
26146363
12.

A mouse model recapitulating human monoclonal heavy chain deposition disease evidences the relevance of proteasome inhibitor therapy.

Bonaud A, Bender S, Touchard G, Lacombe C, Srour N, Delpy L, Oblet C, Druilhe A, Quellard N, Javaugue V, Cogné M, Bridoux F, Sirac C.

Blood. 2015 Aug 6;126(6):757-65. doi: 10.1182/blood-2015-03-630277. Epub 2015 Jun 25.

13.

Kidney diseases associated with monoclonal immunoglobulin M-secreting B-cell lymphoproliferative disorders: a case series of 35 patients.

Chauvet S, Bridoux F, Ecotière L, Javaugue V, Sirac C, Arnulf B, Thierry A, Quellard N, Milin S, Bender S, Goujon JM, Jaccard A, Fermand JP, Touchard G.

Am J Kidney Dis. 2015 Nov;66(5):756-67. doi: 10.1053/j.ajkd.2015.03.035. Epub 2015 May 16.

PMID:
25987261
14.

Mesangial cells as amyloid factory: a unique contribution of animal models.

Sirac C, Bridoux F.

Kidney Int. 2014 Oct;86(4):669-71. doi: 10.1038/ki.2014.182.

15.

AID-induced remodeling of immunoglobulin genes and B cell fate.

Laffleur B, Denis-Lagache N, Péron S, Sirac C, Moreau J, Cogné M.

Oncotarget. 2014 Mar 15;5(5):1118-31. Review.

16.

Light chain deposition disease without glomerular proteinuria: a diagnostic challenge for the nephrologist.

Sicard A, Karras A, Goujon JM, Sirac C, Bender S, Labatut D, Callard P, Sarkozy C, Essig M, Vanhille P, Provot F, Nony A, Nochy D, Ronco P, Bridoux F, Touchard G.

Nephrol Dial Transplant. 2014 Oct;29(10):1894-902. doi: 10.1093/ndt/gfu045. Epub 2014 Mar 11.

PMID:
24619059
17.

B-cell receptor signal strength influences terminal differentiation.

Lechouane F, Bonaud A, Delpy L, Casola S, Oruc Z, Chemin G, Cogné M, Sirac C.

Eur J Immunol. 2013 Mar;43(3):619-28. doi: 10.1002/eji.201242912. Epub 2013 Jan 24.

18.

Al amyloidosis.

Desport E, Bridoux F, Sirac C, Delbes S, Bender S, Fernandez B, Quellard N, Lacombe C, Goujon JM, Lavergne D, Abraham J, Touchard G, Fermand JP, Jaccard A; Centre national de référence pour l’amylose AL et les autres maladies par dépôts d’immunoglobulines monoclonales.

Orphanet J Rare Dis. 2012 Aug 21;7:54. doi: 10.1186/1750-1172-7-54. Review.

19.

Production of human or humanized antibodies in mice.

Laffleur B, Pascal V, Sirac C, Cogné M.

Methods Mol Biol. 2012;901:149-59. doi: 10.1007/978-1-61779-931-0_9.

PMID:
22723099
20.

[Renal disorders associated with monoclonal gammopathies: diagnostic and therapeutic progress].

Bridoux F, Delbes S, Sirac C, Pourreau F, Puyade M, Desport E, Jaccard A, Fermand JP, Touchard G.

Presse Med. 2012 Mar;41(3 Pt 1):276-89. doi: 10.1016/j.lpm.2011.11.008. Epub 2012 Jan 13. Review. French.

PMID:
22244725
21.

The pathogenesis and diagnosis of acute kidney injury in multiple myeloma.

Hutchison CA, Batuman V, Behrens J, Bridoux F, Sirac C, Dispenzieri A, Herrera GA, Lachmann H, Sanders PW; International Kidney and Monoclonal Gammopathy Research Group.

Nat Rev Nephrol. 2011 Nov 1;8(1):43-51. doi: 10.1038/nrneph.2011.168. Review.

22.

Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development.

Tinguely A, Chemin G, Péron S, Sirac C, Reynaud S, Cogné M, Delpy L.

Mol Cell Biol. 2012 Jan;32(1):107-17. doi: 10.1128/MCB.06138-11. Epub 2011 Oct 28.

23.

Strategies to model AL amyloidosis in mice.

Sirac C, Bender S, Jaccard A, Bridoux F, Lacombe C, Touchard G, Cogné M.

Amyloid. 2011 Jun;18 Suppl 1:45-7. doi: 10.3109/13506129.2011.574354016. No abstract available. Erratum in: Amyloid. 2011 Jun;18 Suppl 1:47.

PMID:
21838428
24.

Toward understanding renal Fanconi syndrome: step by step advances through experimental models.

Sirac C, Bridoux F, Essig M, Devuyst O, Touchard G, Cogné M.

Contrib Nephrol. 2011;169:247-261. doi: 10.1159/000313962. Epub 2011 Jan 20. Review.

PMID:
21252524
25.

Multiple RNA surveillance mechanisms cooperate to reduce the amount of nonfunctional Ig kappa transcripts.

Chemin G, Tinguely A, Sirac C, Lechouane F, Duchez S, Cogné M, Delpy L.

J Immunol. 2010 May 1;184(9):5009-17. doi: 10.4049/jimmunol.0902949. Epub 2010 Mar 31.

26.

Premature replacement of mu with alpha immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation.

Duchez S, Amin R, Cogné N, Delpy L, Sirac C, Pascal V, Corthésy B, Cogné M.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3064-9. doi: 10.1073/pnas.0912393107. Epub 2010 Jan 28.

27.

Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity.

Sirac C, Carrion C, Duchez S, Comte I, Cogné M.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7747-52. Epub 2006 May 8.

28.

Role of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome.

Sirac C, Bridoux F, Carrion C, Devuyst O, Fernandez B, Goujon JM, El Hamel C, Aldigier JC, Touchard G, Cogné M.

Blood. 2006 Jul 15;108(2):536-43. Epub 2006 Mar 16.

29.

Interallelic class switch recombination contributes significantly to class switching in mouse B cells.

Reynaud S, Delpy L, Fleury L, Dougier HL, Sirac C, Cogné M.

J Immunol. 2005 May 15;174(10):6176-83.

30.

Fanconi's syndrome induced by a monoclonal Vkappa3 light chain in Waldenstrom's macroglobulinemia.

Bridoux F, Sirac C, Hugue V, Decourt C, Thierry A, Quellard N, Abou-Ayache R, Goujon JM, Cogné M, Touchard G.

Am J Kidney Dis. 2005 Apr;45(4):749-57.

PMID:
15806478
31.
32.

Immunologic basis for the rare occurrence of true nonsecretory plasma cell dyscrasias.

Decourt C, Galea HR, Sirac C, Cogné M.

J Leukoc Biol. 2004 Sep;76(3):528-36. Epub 2004 May 20. Review.

PMID:
15155772
33.

RNA surveillance down-regulates expression of nonfunctional kappa alleles and detects premature termination within the last kappa exon.

Delpy L, Sirac C, Magnoux E, Duchez S, Cogné M.

Proc Natl Acad Sci U S A. 2004 May 11;101(19):7375-80. Epub 2004 May 3.

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