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Items: 12


Activation of PPARγ in Myeloid Cells Promotes Progression of Epithelial Lung Tumors through TGFβ1.

Sippel TR, Johnson AM, Li HY, Hanson D, Nguyen TT, Bullock BL, Poczobutt JM, Kwak JW, Kleczko EK, Weiser-Evans MC, Nemenoff RA.

Mol Cancer Res. 2019 Aug;17(8):1748-1758. doi: 10.1158/1541-7786.MCR-19-0236. Epub 2019 May 14.


Human hematopoietic stem cell maintenance and myeloid cell development in next-generation humanized mouse models.

Sippel TR, Radtke S, Olsen TM, Kiem HP, Rongvaux A.

Blood Adv. 2019 Feb 12;3(3):268-274. doi: 10.1182/bloodadvances.2018023887. No abstract available.


MISTRG mice support engraftment and assessment of nonhuman primate hematopoietic stem and progenitor cells.

Radtke S, Chan YY, Sippel TR, Kiem HP, Rongvaux A.

Exp Hematol. 2019 Feb;70:31-41.e1. doi: 10.1016/j.exphem.2018.12.003. Epub 2018 Dec 25.


Targeted overexpression of prostacyclin synthase inhibits lung tumor progression by recruiting CD4+ T lymphocytes in tumors that express MHC class II.

Li HY, McSharry M, Walker D, Johnson A, Kwak J, Bullock B, Neuwelt A, Poczobutt JM, Sippel TR, Keith RL, Weiser-Evans MCM, Clambey E, Nemenoff RA.

Oncoimmunology. 2018 Feb 13;7(5):e1423182. doi: 10.1080/2162402X.2017.1423182. eCollection 2018.


Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression.

Kwak JW, Laskowski J, Li HY, McSharry MV, Sippel TR, Bullock BL, Johnson AM, Poczobutt JM, Neuwelt AJ, Malkoski SP, Weiser-Evans MC, Lambris JD, Clambey ET, Thurman JM, Nemenoff RA.

Cancer Res. 2018 Jan 1;78(1):143-156. doi: 10.1158/0008-5472.CAN-17-0240. Epub 2017 Nov 8.


The Tumor Microenvironment Regulates Sensitivity of Murine Lung Tumors to PD-1/PD-L1 Antibody Blockade.

Li HY, McSharry M, Bullock B, Nguyen TT, Kwak J, Poczobutt JM, Sippel TR, Heasley LE, Weiser-Evans MC, Clambey ET, Nemenoff RA.

Cancer Immunol Res. 2017 Sep;5(9):767-777. doi: 10.1158/2326-6066.CIR-16-0365. Epub 2017 Aug 17.


Removing hydrochloric acid exhaust products from high performance solid rocket propellant using aluminum-lithium alloy.

Terry BC, Sippel TR, Pfeil MA, Gunduz IE, Son SF.

J Hazard Mater. 2016 Nov 5;317:259-266. doi: 10.1016/j.jhazmat.2016.05.067. Epub 2016 May 27.


Expression Profiling of Macrophages Reveals Multiple Populations with Distinct Biological Roles in an Immunocompetent Orthotopic Model of Lung Cancer.

Poczobutt JM, De S, Yadav VK, Nguyen TT, Li H, Sippel TR, Weiser-Evans MC, Nemenoff RA.

J Immunol. 2016 Mar 15;196(6):2847-59. doi: 10.4049/jimmunol.1502364. Epub 2016 Feb 12.


Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment.

Poczobutt JM, Nguyen TT, Hanson D, Li H, Sippel TR, Weiser-Evans MC, Gijon M, Murphy RC, Nemenoff RA.

J Immunol. 2016 Jan 15;196(2):891-901. doi: 10.4049/jimmunol.1501648. Epub 2015 Dec 11.


Arginase I release from activated neutrophils induces peripheral immunosuppression in a murine model of stroke.

Sippel TR, Shimizu T, Strnad F, Traystman RJ, Herson PS, Waziri A.

J Cereb Blood Flow Metab. 2015 Oct;35(10):1657-63. doi: 10.1038/jcbfm.2015.103. Epub 2015 May 13.


Influence of human immune cells on cancer: studies at the University of Colorado.

Bruno TC, French JD, Jordan KR, Ramirez O, Sippel TR, Borges VF, Haugen BR, McCarter MD, Waziri A, Slansky JE.

Immunol Res. 2013 Mar;55(1-3):22-33. doi: 10.1007/s12026-012-8346-y. Review.


Neutrophil degranulation and immunosuppression in patients with GBM: restoration of cellular immune function by targeting arginase I.

Sippel TR, White J, Nag K, Tsvankin V, Klaassen M, Kleinschmidt-DeMasters BK, Waziri A.

Clin Cancer Res. 2011 Nov 15;17(22):6992-7002. doi: 10.1158/1078-0432.CCR-11-1107. Epub 2011 Sep 26.

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