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Items: 1 to 50 of 130

1.

Oligomeric state, hydrodynamic properties and target recognition of human Calcium and Integrin Binding protein 2 (CIB2).

Dal Cortivo G, Marino V, Iacobucci C, Vallone R, Arlt C, Rehkamp A, Sinz A, Dell'Orco D.

Sci Rep. 2019 Oct 21;9(1):15058. doi: 10.1038/s41598-019-51573-3.

2.

A Simple Cross-Linking/Mass Spectrometry Workflow for Studying System-wide Protein Interactions.

Götze M, Iacobucci C, Ihling CH, Sinz A.

Anal Chem. 2019 Aug 6;91(15):10236-10244. doi: 10.1021/acs.analchem.9b02372. Epub 2019 Jul 19.

PMID:
31283178
3.

First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.

Iacobucci C, Piotrowski C, Aebersold R, Amaral BC, Andrews P, Bernfur K, Borchers C, Brodie NI, Bruce JE, Cao Y, Chaignepain S, Chavez JD, Claverol S, Cox J, Davis T, Degliesposti G, Dong MQ, Edinger N, Emanuelsson C, Gay M, Götze M, Gomes-Neto F, Gozzo FC, Gutierrez C, Haupt C, Heck AJR, Herzog F, Huang L, Hoopmann MR, Kalisman N, Klykov O, Kukačka Z, Liu F, MacCoss MJ, Mechtler K, Mesika R, Moritz RL, Nagaraj N, Nesati V, Neves-Ferreira AGC, Ninnis R, Novák P, O'Reilly FJ, Pelzing M, Petrotchenko E, Piersimoni L, Plasencia M, Pukala T, Rand KD, Rappsilber J, Reichmann D, Sailer C, Sarnowski CP, Scheltema RA, Schmidt C, Schriemer DC, Shi Y, Skehel JM, Slavin M, Sobott F, Solis-Mezarino V, Stephanowitz H, Stengel F, Stieger CE, Trabjerg E, Trnka M, Vilaseca M, Viner R, Xiang Y, Yilmaz S, Zelter A, Ziemianowicz D, Leitner A, Sinz A.

Anal Chem. 2019 Jun 4;91(11):6953-6961. doi: 10.1021/acs.analchem.9b00658. Epub 2019 May 22.

4.

Profiling of Seed Proteome in Pea (Pisum sativum L.) Lines Characterized with High and Low Responsivity to Combined Inoculation with Nodule Bacteria and Arbuscular Mycorrhizal Fungi.

Mamontova T, Afonin AM, Ihling C, Soboleva A, Lukasheva E, Sulima AS, Shtark OY, Akhtemova GA, Povydysh MN, Sinz A, Frolov A, Zhukov VA, Tikhonovich IA.

Molecules. 2019 Apr 23;24(8). pii: E1603. doi: 10.3390/molecules24081603.

5.

Cytochrome bcc-aa3 Oxidase Supercomplexes in the Aerobic Respiratory Chain of Streptomyces coelicolor A3(2).

Falke D, Fischer M, Biefel B, Ihling C, Hammerschmidt C, Reinefeld K, Haase A, Sinz A, Sawers RG.

J Mol Microbiol Biotechnol. 2018;28(6):255-268. doi: 10.1159/000496390. Epub 2019 Mar 12.

PMID:
30861513
6.

Structural Investigation of Proteins and Protein Complexes by Chemical Cross-Linking/Mass Spectrometry.

Piotrowski C, Sinz A.

Adv Exp Med Biol. 2018;1105:101-121. doi: 10.1007/978-981-13-2200-6_8. Review.

PMID:
30617826
7.

A cross-linking/mass spectrometry workflow based on MS-cleavable cross-linkers and the MeroX software for studying protein structures and protein-protein interactions.

Iacobucci C, Götze M, Ihling CH, Piotrowski C, Arlt C, Schäfer M, Hage C, Schmidt R, Sinz A.

Nat Protoc. 2018 Dec;13(12):2864-2889. doi: 10.1038/s41596-018-0068-8.

PMID:
30382245
8.

Molecular Details of Retinal Guanylyl Cyclase 1/GCAP-2 Interaction.

Rehkamp A, Tänzler D, Iacobucci C, Golbik RP, Ihling CH, Sinz A.

Front Mol Neurosci. 2018 Sep 19;11:330. doi: 10.3389/fnmol.2018.00330. eCollection 2018.

9.

Reconstitution of mammalian cleavage factor II involved in 3' processing of mRNA precursors.

Schäfer P, Tüting C, Schönemann L, Kühn U, Treiber T, Treiber N, Ihling C, Graber A, Keller W, Meister G, Sinz A, Wahle E.

RNA. 2018 Dec;24(12):1721-1737. doi: 10.1261/rna.068056.118. Epub 2018 Aug 23.

10.

Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB.

Bräuning B, Bertosin E, Praetorius F, Ihling C, Schatt A, Adler A, Richter K, Sinz A, Dietz H, Groll M.

Nat Commun. 2018 May 4;9(1):1806. doi: 10.1038/s41467-018-04139-2.

11.

The First MS-Cleavable, Photo-Thiol-Reactive Cross-Linker for Protein Structural Studies.

Iacobucci C, Piotrowski C, Rehkamp A, Ihling CH, Sinz A.

J Am Soc Mass Spectrom. 2019 Jan;30(1):139-148. doi: 10.1007/s13361-018-1952-8. Epub 2018 Apr 20. Erratum in: J Am Soc Mass Spectrom. 2019 Feb 11;:.

PMID:
29679287
12.

Free radical-initiated peptide sequencing (FRIPS)-based cross-linkers for improved peptide and protein structure analysis.

Iacobucci C, Schäfer M, Sinz A.

Mass Spectrom Rev. 2019 Mar;38(2):187-201. doi: 10.1002/mas.21568. Epub 2018 Apr 16. Review.

PMID:
29660147
13.

Crosslinking Mass Spectrometry Goes In-Tissue.

Sinz A.

Cell Syst. 2018 Jan 24;6(1):10-12. doi: 10.1016/j.cels.2018.01.005.

14.

Carboxyl-Photo-Reactive MS-Cleavable Cross-Linkers: Unveiling a Hidden Aspect of Diazirine-Based Reagents.

Iacobucci C, Götze M, Piotrowski C, Arlt C, Rehkamp A, Ihling C, Hage C, Sinz A.

Anal Chem. 2018 Feb 20;90(4):2805-2809. doi: 10.1021/acs.analchem.7b04915. Epub 2018 Feb 8.

PMID:
29376325
15.

Cross-Linking/Mass Spectrometry for Studying Protein Structures and Protein-Protein Interactions: Where Are We Now and Where Should We Go from Here?

Sinz A.

Angew Chem Int Ed Engl. 2018 May 28;57(22):6390-6396. doi: 10.1002/anie.201709559. Epub 2018 Apr 19. Review.

PMID:
29334167
16.

The First Zero-Length Mass Spectrometry-Cleavable Cross-Linker for Protein Structure Analysis.

Hage C, Iacobucci C, Rehkamp A, Arlt C, Sinz A.

Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14551-14555. doi: 10.1002/anie.201708273. Epub 2017 Oct 9.

PMID:
28876504
17.

To Be or Not to Be? Five Guidelines to Avoid Misassignments in Cross-Linking/Mass Spectrometry.

Iacobucci C, Sinz A.

Anal Chem. 2017 Aug 1;89(15):7832-7835. doi: 10.1021/acs.analchem.7b02316. Epub 2017 Jul 21.

PMID:
28723100
18.

A Novel MS-Cleavable Azo Cross-Linker for Peptide Structure Analysis by Free Radical Initiated Peptide Sequencing (FRIPS).

Iacobucci C, Hage C, Schäfer M, Sinz A.

J Am Soc Mass Spectrom. 2017 Oct;28(10):2039-2053. doi: 10.1007/s13361-017-1744-6. Epub 2017 Jul 17.

PMID:
28717933
19.

Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch.

Götze M, Dufourt J, Ihling C, Rammelt C, Pierson S, Sambrani N, Temme C, Sinz A, Simonelig M, Wahle E.

RNA. 2017 Oct;23(10):1552-1568. doi: 10.1261/rna.062208.117. Epub 2017 Jul 12.

20.

Novel Concepts of MS-Cleavable Cross-linkers for Improved Peptide Structure Analysis.

Hage C, Falvo F, Schäfer M, Sinz A.

J Am Soc Mass Spectrom. 2017 Oct;28(10):2022-2038. doi: 10.1007/s13361-017-1712-1. Epub 2017 Jun 26.

PMID:
28653243
21.

Global proteomic analysis of advanced glycation end products in the Arabidopsis proteome provides evidence for age-related glycation hot spots.

Bilova T, Paudel G, Shilyaev N, Schmidt R, Brauch D, Tarakhovskaya E, Milrud S, Smolikova G, Tissier A, Vogt T, Sinz A, Brandt W, Birkemeyer C, Wessjohann LA, Frolov A.

J Biol Chem. 2017 Sep 22;292(38):15758-15776. doi: 10.1074/jbc.M117.794537. Epub 2017 Jun 13.

22.

Azide-Modified Membrane Lipids: Synthesis, Properties, and Reactivity.

Lindner S, Gruhle K, Schmidt R, Garamus VM, Ramsbeck D, Hause G, Meister A, Sinz A, Drescher S.

Langmuir. 2017 May 23;33(20):4960-4973. doi: 10.1021/acs.langmuir.7b00228. Epub 2017 May 10.

PMID:
28457130
23.

Combining affinity enrichment, cross-linking with photo amino acids, and mass spectrometry for probing protein kinase D2 interactions.

Häupl B, Ihling CH, Sinz A.

Proteomics. 2017 May;17(10):e1600459. doi: 10.1002/pmic.201600459.

PMID:
28387473
24.

Presynaptic Calmodulin targets: lessons from structural proteomics.

Lipstein N, Göth M, Piotrowski C, Pagel K, Sinz A, Jahn O.

Expert Rev Proteomics. 2017 Mar;14(3):223-242. doi: 10.1080/14789450.2017.1275966. Epub 2017 Feb 20. Review.

PMID:
28222617
25.

Improved single-step enrichment methods of cross-linked products for protein structure analysis and protein interaction mapping.

Schmidt R, Sinz A.

Anal Bioanal Chem. 2017 Mar;409(9):2393-2400. doi: 10.1007/s00216-017-0185-1. Epub 2017 Jan 12.

PMID:
28083664
26.

An Integrated Mass Spectrometry Based Approach to Probe the Structure of the Full-Length Wild-Type Tetrameric p53 Tumor Suppressor.

Arlt C, Flegler V, Ihling CH, Schäfer M, Thondorf I, Sinz A.

Angew Chem Int Ed Engl. 2017 Jan 2;56(1):275-279. doi: 10.1002/anie.201609826. Epub 2016 Nov 29.

PMID:
27897373
27.

Osmotic stress is accompanied by protein glycation in Arabidopsis thaliana.

Paudel G, Bilova T, Schmidt R, Greifenhagen U, Berger R, Tarakhovskaya E, Stöckhardt S, Balcke GU, Humbeck K, Brandt W, Sinz A, Vogt T, Birkemeyer C, Wessjohann L, Frolov A.

J Exp Bot. 2016 Dec;67(22):6283-6295. Epub 2016 Nov 10.

28.

Identification of low abundance cyclophilins in human plasma.

Schumann M, Ihling CH, Prell E, Schierhorn A, Sinz A, Fischer G, Schiene-Fischer C, Malešević M.

Proteomics. 2016 Nov;16(21):2815-2826. doi: 10.1002/pmic.201600221. Epub 2016 Oct 12.

PMID:
27586231
29.

Mass spectrometry-based secretome analysis of non-small cell lung cancer cell lines.

Bosse K, Haneder S, Arlt C, Ihling CH, Seufferlein T, Sinz A.

Proteomics. 2016 Nov;16(21):2801-2814. doi: 10.1002/pmic.201600297. Epub 2016 Sep 21.

PMID:
27569058
30.

Divide and conquer: cleavable cross-linkers to study protein conformation and protein-protein interactions.

Sinz A.

Anal Bioanal Chem. 2017 Jan;409(1):33-44. doi: 10.1007/s00216-016-9941-x. Epub 2016 Oct 12. Review.

PMID:
27734140
31.

Protein Interaction Network of Human Protein Kinase D2 Revealed by Chemical Cross-Linking/Mass Spectrometry.

Häupl B, Ihling CH, Sinz A.

J Proteome Res. 2016 Oct 7;15(10):3686-3699. Epub 2016 Sep 2.

PMID:
27559607
32.

Conformational Shift of a β-Hairpin Peptide upon Complex Formation with an Oligo-proline Peptide Studied by Mass Spectrometry.

Kölbel K, Warnke S, Seo J, von Helden G, Moretti R, Meiler J, Pagel K, Sinz A.

ChemistrySelect. 2016 Aug 16;1(13):3651-3656. doi: 10.1002/slct.201600934. Epub 2016 Aug 19.

33.

Integrated Workflow for Structural Proteomics Studies Based on Cross-Linking/Mass Spectrometry with an MS/MS Cleavable Cross-Linker.

Arlt C, Götze M, Ihling CH, Hage C, Schäfer M, Sinz A.

Anal Chem. 2016 Aug 16;88(16):7930-7. doi: 10.1021/acs.analchem.5b04853. Epub 2016 Jul 28.

PMID:
27428000
34.

Dissociation Behavior of a TEMPO-Active Ester Cross-Linker for Peptide Structure Analysis by Free Radical Initiated Peptide Sequencing (FRIPS) in Negative ESI-MS.

Hage C, Ihling CH, Götze M, Schäfer M, Sinz A.

J Am Soc Mass Spectrom. 2017 Jan;28(1):56-68. doi: 10.1007/s13361-016-1426-9. Epub 2016 Jul 14.

PMID:
27418170
35.

Monitoring Solution Structures of Peroxisome Proliferator-Activated Receptor β/δ upon Ligand Binding.

Schwarz R, Tänzler D, Ihling CH, Sinz A.

PLoS One. 2016 Mar 18;11(3):e0151412. doi: 10.1371/journal.pone.0151412. eCollection 2016.

36.

Combining Amine-Reactive Cross-Linkers and Photo-Reactive Amino Acids for 3D-Structure Analysis of Proteins and Protein Complexes.

Lössl P, Sinz A.

Methods Mol Biol. 2016;1394:109-127. doi: 10.1007/978-1-4939-3341-9_9.

PMID:
26700045
37.

The Y3** ncRNA promotes the 3' end processing of histone mRNAs.

Köhn M, Ihling C, Sinz A, Krohn K, Hüttelmaier S.

Genes Dev. 2015 Oct 1;29(19):1998-2003. doi: 10.1101/gad.266486.115.

38.

Acidosis-Induced Changes in Proteome Patterns of the Prostate Cancer-Derived Tumor Cell Line AT-1.

Ihling A, Ihling CH, Sinz A, Gekle M.

J Proteome Res. 2015 Sep 4;14(9):3996-4004. doi: 10.1021/acs.jproteome.5b00503. Epub 2015 Aug 4.

PMID:
26214752
39.

Chemical cross-linking and native mass spectrometry: A fruitful combination for structural biology.

Sinz A, Arlt C, Chorev D, Sharon M.

Protein Sci. 2015 Aug;24(8):1193-209. doi: 10.1002/pro.2696. Epub 2015 May 27. Review.

40.

Dissociation behavior of a bifunctional tempo-active ester reagent for peptide structure analysis by free radical initiated peptide sequencing (FRIPS) mass spectrometry.

Ihling C, Falvo F, Kratochvil I, Sinz A, Schäfer M.

J Mass Spectrom. 2015 Feb;50(2):396-406. doi: 10.1002/jms.3543.

PMID:
25800022
41.

Structure of full-length p53 tumor suppressor probed by chemical cross-linking and mass spectrometry.

Arlt C, Ihling CH, Sinz A.

Proteomics. 2015 Aug;15(16):2746-55. doi: 10.1002/pmic.201400549. Epub 2015 Apr 21.

PMID:
25728495
42.

Extending the cross-linking/mass spectrometry strategy: Facile incorporation of photo-activatable amino acids into the model protein calmodulin in Escherichia coli cells.

Piotrowski C, Ihling CH, Sinz A.

Methods. 2015 Nov 1;89:121-7. doi: 10.1016/j.ymeth.2015.02.012. Epub 2015 Feb 26.

PMID:
25726908
43.

Analysis of nidogen-1/laminin γ1 interaction by cross-linking, mass spectrometry, and computational modeling reveals multiple binding modes.

Lössl P, Kölbel K, Tänzler D, Nannemann D, Ihling CH, Keller MV, Schneider M, Zaucke F, Meiler J, Sinz A.

PLoS One. 2014 Nov 11;9(11):e112886. doi: 10.1371/journal.pone.0112886. eCollection 2014.

44.

Automated assignment of MS/MS cleavable cross-links in protein 3D-structure analysis.

Götze M, Pettelkau J, Fritzsche R, Ihling CH, Schäfer M, Sinz A.

J Am Soc Mass Spectrom. 2015 Jan;26(1):83-97. doi: 10.1007/s13361-014-1001-1. Epub 2014 Sep 27.

PMID:
25261217
45.

Mapping cell envelope and periplasm protein interactions of Escherichia coli respiratory formate dehydrogenases by chemical cross-linking and mass spectrometry.

Zorn M, Ihling CH, Golbik R, Sawers RG, Sinz A.

J Proteome Res. 2014 Dec 5;13(12):5524-35. doi: 10.1021/pr5004906. Epub 2014 Oct 3.

PMID:
25251153
46.

The advancement of chemical cross-linking and mass spectrometry for structural proteomics: from single proteins to protein interaction networks.

Sinz A.

Expert Rev Proteomics. 2014 Dec;11(6):733-43. doi: 10.1586/14789450.2014.960852. Epub 2014 Sep 16. Review.

PMID:
25227871
47.

Reliable identification of cross-linked products in protein interaction studies by 13C-labeled p-benzoylphenylalanine.

Pettelkau J, Ihling CH, Frohberg P, van Werven L, Jahn O, Sinz A.

J Am Soc Mass Spectrom. 2014 Sep;25(9):1628-41. doi: 10.1007/s13361-014-0944-6. Epub 2014 Jul 17.

PMID:
25031183
48.

Pyruvate formate-lyase interacts directly with the formate channel FocA to regulate formate translocation.

Doberenz C, Zorn M, Falke D, Nannemann D, Hunger D, Beyer L, Ihling CH, Meiler J, Sinz A, Sawers RG.

J Mol Biol. 2014 Jul 29;426(15):2827-39. doi: 10.1016/j.jmb.2014.05.023. Epub 2014 Jun 2.

49.

Structural insights into calmodulin/Munc13 interaction.

Herbst S, Lipstein N, Jahn O, Sinz A.

Biol Chem. 2014 Jul;395(7-8):763-8. doi: 10.1515/hsz-2014-0134. Review.

PMID:
24854537
50.

Preparation of monolithic affinity media for nano-liquid chromatography applications.

Sproß J, Sinz A.

Methods Mol Biol. 2014;1129:351-64. doi: 10.1007/978-1-62703-977-2_26.

PMID:
24648087

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