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Items: 1 to 50 of 58

1.

Noise-induced sleep disruption increases weight gain and decreases energy metabolism in female rats.

Coborn JE, Lessie RE, Sinton CM, Rance NE, Perez-Leighton CE, Teske JA.

Int J Obes (Lond). 2018 Dec 19. doi: 10.1038/s41366-018-0293-9. [Epub ahead of print]

2.

Role of orexin-A in the ventrolateral preoptic area on components of total energy expenditure.

Coborn JE, DePorter DP, Mavanji V, Sinton CM, Kotz CM, Billington CJ, Teske JA.

Int J Obes (Lond). 2017 Aug;41(8):1256-1262. doi: 10.1038/ijo.2017.92. Epub 2017 Apr 10.

PMID:
28392556
3.

Mesolimbic neuropeptide W coordinates stress responses under novel environments.

Motoike T, Long JM, Tanaka H, Sinton CM, Skach A, Williams SC, Hammer RE, Sakurai T, Yanagisawa M.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):6023-8. doi: 10.1073/pnas.1518658113. Epub 2016 May 2.

4.

Transient expression of neuropeptide W in postnatal mouse hypothalamus--a putative regulator of energy homeostasis.

Motoike T, Skach AG, Godwin JK, Sinton CM, Yamazaki M, Abe M, Natsume R, Sakimura K, Yanagisawa M.

Neuroscience. 2015 Aug 20;301:323-37. doi: 10.1016/j.neuroscience.2015.06.014. Epub 2015 Jun 11. Erratum in: Neuroscience. 2015 Sep 10;303():630.

PMID:
26073698
5.

Promotion of Wakefulness and Energy Expenditure by Orexin-A in the Ventrolateral Preoptic Area.

Mavanji V, Perez-Leighton CE, Kotz CM, Billington CJ, Parthasarathy S, Sinton CM, Teske JA.

Sleep. 2015 Sep 1;38(9):1361-70. doi: 10.5665/sleep.4970.

6.

GABAA receptor-mediated input change on orexin neurons following sleep deprivation in mice.

Matsuki T, Takasu M, Hirose Y, Murakoshi N, Sinton CM, Motoike T, Yanagisawa M.

Neuroscience. 2015 Jan 22;284:217-24. doi: 10.1016/j.neuroscience.2014.09.063. Epub 2014 Oct 5.

PMID:
25286384
7.

Behavioral and biochemical dissociation of arousal and homeostatic sleep need influenced by prior wakeful experience in mice.

Suzuki A, Sinton CM, Greene RW, Yanagisawa M.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10288-93. doi: 10.1073/pnas.1308295110. Epub 2013 May 28.

8.

Glut1 deficiency (G1D): epilepsy and metabolic dysfunction in a mouse model of the most common human phenotype.

Marin-Valencia I, Good LB, Ma Q, Duarte J, Bottiglieri T, Sinton CM, Heilig CW, Pascual JM.

Neurobiol Dis. 2012 Oct;48(1):92-101. doi: 10.1016/j.nbd.2012.04.011. Epub 2012 Apr 23.

9.

Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis.

Amiri A, Cho W, Zhou J, Birnbaum SG, Sinton CM, McKay RM, Parada LF.

J Neurosci. 2012 Apr 25;32(17):5880-90. doi: 10.1523/JNEUROSCI.5462-11.2012.

10.

Differential roles of orexin receptor-1 and -2 in the regulation of non-REM and REM sleep.

Mieda M, Hasegawa E, Kisanuki YY, Sinton CM, Yanagisawa M, Sakurai T.

J Neurosci. 2011 Apr 27;31(17):6518-26. doi: 10.1523/JNEUROSCI.6506-10.2011.

11.

Orexin/hypocretin plays a role in the response to physiological disequilibrium.

Sinton CM.

Sleep Med Rev. 2011 Jun;15(3):197-207. doi: 10.1016/j.smrv.2010.12.003. Epub 2011 Jan 26. Review.

PMID:
21269851
12.

Loss of Goosecoid-like and DiGeorge syndrome critical region 14 in interpeduncular nucleus results in altered regulation of rapid eye movement sleep.

Funato H, Sato M, Sinton CM, Gautron L, Williams SC, Skach A, Elmquist JK, Skoultchi AI, Yanagisawa M.

Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18155-60. doi: 10.1073/pnas.1012764107. Epub 2010 Oct 4.

13.

Validation of a novel method to interrupt sleep in the mouse.

Sinton CM, Kovakkattu D, Friese RS.

J Neurosci Methods. 2009 Oct 30;184(1):71-8. doi: 10.1016/j.jneumeth.2009.07.026. Epub 2009 Jul 29.

PMID:
19646474
14.

Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5.

Hawasli AH, Koovakkattu D, Hayashi K, Anderson AE, Powell CM, Sinton CM, Bibb JA, Cooper DC.

PLoS One. 2009 Jun 4;4(6):e5808. doi: 10.1371/journal.pone.0005808.

15.

Sleep deprivation after septic insult increases mortality independent of age.

Friese RS, Bruns B, Sinton CM.

J Trauma. 2009 Jan;66(1):50-4. doi: 10.1097/TA.0b013e318190c3a1.

PMID:
19131805
16.

Abnormal response of melanin-concentrating hormone deficient mice to fasting: hyperactivity and rapid eye movement sleep suppression.

Willie JT, Sinton CM, Maratos-Flier E, Yanagisawa M.

Neuroscience. 2008 Oct 28;156(4):819-29. doi: 10.1016/j.neuroscience.2008.08.048. Epub 2008 Aug 31.

17.

A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice.

Ogawa S, Kwon CH, Zhou J, Koovakkattu D, Parada LF, Sinton CM.

Brain Res. 2007 Sep 7;1168:112-23. Epub 2007 Jul 20.

PMID:
17706614
18.

Epigenetic modulation of seizure-induced neurogenesis and cognitive decline.

Jessberger S, Nakashima K, Clemenson GD Jr, Mejia E, Mathews E, Ure K, Ogawa S, Sinton CM, Gage FH, Hsieh J.

J Neurosci. 2007 May 30;27(22):5967-75.

19.

Neuropeptide B-deficient mice demonstrate hyperalgesia in response to inflammatory pain.

Kelly MA, Beuckmann CT, Williams SC, Sinton CM, Motoike T, Richardson JA, Hammer RE, Garry MG, Yanagisawa M.

Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9942-7. Epub 2005 Jun 27.

20.

Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates.

Willie JT, Renthal W, Chemelli RM, Miller MS, Scammell TE, Yanagisawa M, Sinton CM.

Neuroscience. 2005;130(4):983-95.

PMID:
15652995
21.

Orexin neurons function in an efferent pathway of a food-entrainable circadian oscillator in eliciting food-anticipatory activity and wakefulness.

Mieda M, Williams SC, Sinton CM, Richardson JA, Sakurai T, Yanagisawa M.

J Neurosci. 2004 Nov 17;24(46):10493-501.

22.

Neurophysiological mechanisms of sleep and wakefulness: a question of balance.

Sinton CM, McCarley RW.

Semin Neurol. 2004 Sep;24(3):211-23. Review.

PMID:
15449215
23.

Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat.

Beuckmann CT, Sinton CM, Williams SC, Richardson JA, Hammer RE, Sakurai T, Yanagisawa M.

J Neurosci. 2004 May 5;24(18):4469-77.

24.

Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice.

Mieda M, Willie JT, Hara J, Sinton CM, Sakurai T, Yanagisawa M.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4649-54. Epub 2004 Mar 16.

25.

N-type calcium channel alpha1B subunit (Cav2.2) knock-out mice display hyperactivity and vigilance state differences.

Beuckmann CT, Sinton CM, Miyamoto N, Ino M, Yanagisawa M.

J Neurosci. 2003 Jul 30;23(17):6793-7.

26.

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes.

Willie JT, Chemelli RM, Sinton CM, Tokita S, Williams SC, Kisanuki YY, Marcus JN, Lee C, Elmquist JK, Kohlmeier KA, Leonard CS, Richardson JA, Hammer RE, Yanagisawa M.

Neuron. 2003 Jun 5;38(5):715-30.

27.

Rapid eye movement sleep deprivation modifies expression of long-term potentiation in visual cortex of immature rats.

Shaffery JP, Sinton CM, Bissette G, Roffwarg HP, Marks GA.

Neuroscience. 2002;110(3):431-43.

PMID:
11906784
28.

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

Hara J, Beuckmann CT, Nambu T, Willie JT, Chemelli RM, Sinton CM, Sugiyama F, Yagami K, Goto K, Yanagisawa M, Sakurai T.

Neuron. 2001 May;30(2):345-54.

29.

Gene therapy to prevent organophosphate intoxication.

Cowan J, Sinton CM, Varley AW, Wians FH, Haley RW, Munford RS.

Toxicol Appl Pharmacol. 2001 May 15;173(1):1-6.

PMID:
11350209
30.

To eat or to sleep? Orexin in the regulation of feeding and wakefulness.

Willie JT, Chemelli RM, Sinton CM, Yanagisawa M.

Annu Rev Neurosci. 2001;24:429-58. Review.

PMID:
11283317
31.

Upregulation of estrogen receptors in the forebrain of aromatase knockout (ArKO) mice.

Agarwal VR, Sinton CM, Liang C, Fisher C, German DC, Simpson ER.

Mol Cell Endocrinol. 2000 Apr 25;162(1-2):9-16.

PMID:
10854693
32.

Stressful manipulations that elevate corticosterone reduce blood-brain barrier permeability to pyridostigmine in the Rat.

Sinton CM, Fitch TE, Petty F, Haley RW.

Toxicol Appl Pharmacol. 2000 May 15;165(1):99-105.

PMID:
10814558
33.

Neuroanatomical and neurophysiological aspects of sleep: basic science and clinical relevance.

Sinton CM, McCarley RW.

Semin Clin Neuropsychiatry. 2000 Jan;5(1):6-19. Review.

PMID:
10704534
34.

Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia.

Holt DJ, Herman MM, Hyde TM, Kleinman JE, Sinton CM, German DC, Hersh LB, Graybiel AM, Saper CB.

Neuroscience. 1999;94(1):21-31.

PMID:
10613493
35.

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.

Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, Lee C, Richardson JA, Williams SC, Xiong Y, Kisanuki Y, Fitch TE, Nakazato M, Hammer RE, Saper CB, Yanagisawa M.

Cell. 1999 Aug 20;98(4):437-51.

36.

The effects of leptin on REM sleep and slow wave delta in rats are reversed by food deprivation.

Sinton CM, Fitch TE, Gershenfeld HK.

J Sleep Res. 1999 Sep;8(3):197-203.

37.

Inhibition of striatal energy metabolism produces cell loss in the ipsilateral substantia nigra.

Sonsalla PK, Manzino L, Sinton CM, Liang CL, German DC, Zeevalk GD.

Brain Res. 1997 Oct 31;773(1-2):223-6.

PMID:
9409726
38.
39.

The neurotoxin MPTP causes degeneration of specific nucleus A8, A9 and A10 dopaminergic neurons in the mouse.

German DC, Nelson EL, Liang CL, Speciale SG, Sinton CM, Sonsalla PK.

Neurodegeneration. 1996 Dec;5(4):299-312.

PMID:
9117541
40.

Midbrain dopaminergic neurons in the mouse: co-localization with Calbindin-D28K and calretinin.

Liang CL, Sinton CM, German DC.

Neuroscience. 1996 Nov;75(2):523-33.

PMID:
8931015
41.

Midbrain dopaminergic neurons in the mouse: computer-assisted mapping.

Nelson EL, Liang CL, Sinton CM, German DC.

J Comp Neurol. 1996 Jun 3;369(3):361-71.

PMID:
8743418
42.
43.

A microcomputer-based sleep stage analyzer.

Goeller CJ, Sinton CM.

Comput Methods Programs Biomed. 1989 May;29(1):31-6.

PMID:
2714077
44.

The effectiveness of different isomers of octanol as blockers of harmaline-induced tremor.

Sinton CM, Krosser BI, Walton KD, LlinĂ¡s RR.

Pflugers Arch. 1989 May;414(1):31-6.

PMID:
2542888
45.

The influence of chronic caffeine administration on sleep parameters in the cat.

Sinton CM, Petitjean F.

Pharmacol Biochem Behav. 1989 Feb;32(2):459-62.

PMID:
2727004
46.

Cholecystokinin modulates neurotransmission through the dentate gyrus.

Sinton CM.

Neurosci Lett. 1988 Dec 19;95(1-3):341-6.

PMID:
2852324
47.

Electrophysiological evidence for a functional differentiation between subtypes of the 5-HT1 receptor.

Sinton CM, Fallon SL.

Eur J Pharmacol. 1988 Nov 22;157(2-3):173-81.

PMID:
2906291
48.
49.
50.

Cholecystokinin and an evoked response in the dentate gyrus.

Sinton CM.

Neuropeptides. 1988 Jul;12(1):29-34.

PMID:
3419558

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