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Items: 1 to 50 of 213

1.

Palm Fruit Bioactives augment expression of Tyrosine Hydroxylase in the Nile Grass Rat basal ganglia and alter the colonic microbiome.

Weinberg RP, Koledova VV, Subramaniam A, Schneider K, Artamonova A, Sambanthamurthi R, Hayes KC, Sinskey AJ, Rha C.

Sci Rep. 2019 Dec 9;9(1):18625. doi: 10.1038/s41598-019-54461-y.

2.

Palm Fruit Bioactives modulate human astrocyte activity in vitro altering the cytokine secretome reducing levels of TNFα, RANTES and IP-10.

Weinberg RP, Koledova VV, Schneider K, Sambandan TG, Grayson A, Zeidman G, Artamonova A, Sambanthamurthi R, Fairus S, Sinskey AJ, Rha C.

Sci Rep. 2018 Nov 6;8(1):16423. doi: 10.1038/s41598-018-34763-3.

3.

Oil Palm Phenolics Inhibit the In Vitro Aggregation of β-Amyloid Peptide into Oligomeric Complexes.

Weinberg RP, Koledova VV, Shin H, Park JH, Tan YA, Sinskey AJ, Sambanthamurthi R, Rha C.

Int J Alzheimers Dis. 2018 Jan 31;2018:7608038. doi: 10.1155/2018/7608038. eCollection 2018.

4.

Yeast-Based Synthetic Biology Platform for Antimicrobial Peptide Production.

Cao J, de la Fuente-Nunez C, Ou RW, Torres MT, Pande SG, Sinskey AJ, Lu TK.

ACS Synth Biol. 2018 Mar 16;7(3):896-902. doi: 10.1021/acssynbio.7b00396. Epub 2018 Feb 12.

PMID:
29366323
5.

Production of Functional Anti-Ebola Antibodies in Pichia pastoris.

Purcell O, Opdensteinen P, Chen W, Lowenhaupt K, Brown A, Hermann M, Cao J, Tenhaef N, Kallweit E, Kastilan R, Sinskey AJ, Perez-Pinera P, Buyel JF, Lu TK.

ACS Synth Biol. 2017 Dec 15;6(12):2183-2190. doi: 10.1021/acssynbio.7b00234. Epub 2017 Aug 17.

PMID:
28786662
6.

Correction for Brigham et al., "Whole-Genome Microarray and Gene Deletion Studies Reveal Regulation of the Polyhydroxyalkanoate Production Cycle by the Stringent Response in Ralstonia eutropha H16".

Brigham CJ, Speth DR, Rha C, Sinskey AJ.

Appl Environ Microbiol. 2017 Jul 17;83(15). pii: e01216-17. doi: 10.1128/AEM.01216-17. Print 2017 Aug 1. No abstract available.

7.

Over expression of GroESL in Cupriavidus necator for heterotrophic and autotrophic isopropanol production.

Marc J, Grousseau E, Lombard E, Sinskey AJ, Gorret N, Guillouet SE.

Metab Eng. 2017 Jul;42:74-84. doi: 10.1016/j.ymben.2017.05.007. Epub 2017 Jun 4.

PMID:
28591561
8.

Absence of ppGpp Leads to Increased Mobilization of Intermediately Accumulated Poly(3-Hydroxybutyrate) in Ralstonia eutropha H16.

Juengert JR, Borisova M, Mayer C, Wolz C, Brigham CJ, Sinskey AJ, Jendrossek D.

Appl Environ Microbiol. 2017 Jun 16;83(13). pii: e00755-17. doi: 10.1128/AEM.00755-17. Print 2017 Jul 1.

9.

Corrigendum to "Experimental evolution and gene knockout studies reveal AcrA-mediated isobutanol tolerance in Ralstonia eutropha" [J Biosci Bioeng 122 (2016) 64-69].

Bernardi AC, Gai CS, Lu J, Sinskey AJ, Brigham CJ.

J Biosci Bioeng. 2017 May;123(5):658. doi: 10.1016/j.jbiosc.2017.01.010. Epub 2017 Feb 6. No abstract available.

PMID:
28185833
10.

Leveraging Industry-Academia Collaborations in Adaptive Biomedical Innovation.

Stewart SR, Barone PW, Bellisario A, Cooney CL, Sharp PA, Sinskey AJ, Natesan S, Springs SL.

Clin Pharmacol Ther. 2016 Dec;100(6):647-653. doi: 10.1002/cpt.504. Epub 2016 Oct 22.

PMID:
27617845
11.

Experimental evolution and gene knockout studies reveal AcrA-mediated isobutanol tolerance in Ralstonia eutropha.

Bernardi AC, Gai CS, Lu J, Sinskey AJ, Brigham CJ.

J Biosci Bioeng. 2016 Jul;122(1):64-9. doi: 10.1016/j.jbiosc.2015.12.015. Epub 2016 Jan 19.

PMID:
26811221
12.

Metabolic engineering Corynebacterium glutamicum to produce triacylglycerols.

Plassmeier J, Li Y, Rueckert C, Sinskey AJ.

Metab Eng. 2016 Jan;33:86-97. doi: 10.1016/j.ymben.2015.11.002. Epub 2015 Nov 29.

PMID:
26645801
13.

Lignocellulose-derived inhibitors improve lipid extraction from wet Rhodococcus opacus cells.

Kurosawa K, Anthony Debono C, Sinskey AJ.

Bioresour Technol. 2015 Oct;193:206-12. doi: 10.1016/j.biortech.2015.05.103. Epub 2015 Jun 6.

PMID:
26141279
14.

Tolerance and adaptive evolution of triacylglycerol-producing Rhodococcus opacus to lignocellulose-derived inhibitors.

Kurosawa K, Laser J, Sinskey AJ.

Biotechnol Biofuels. 2015 May 13;8:76. doi: 10.1186/s13068-015-0258-3. eCollection 2015.

15.

3D molecular MR imaging of liver fibrosis and response to rapamycin therapy in a bile duct ligation rat model.

Farrar CT, DePeralta DK, Day H, Rietz TA, Wei L, Lauwers GY, Keil B, Subramaniam A, Sinskey AJ, Tanabe KK, Fuchs BC, Caravan P.

J Hepatol. 2015 Sep;63(3):689-96. doi: 10.1016/j.jhep.2015.04.029. Epub 2015 May 25.

16.

Engineering L-arabinose metabolism in triacylglycerol-producing Rhodococcus opacus for lignocellulosic fuel production.

Kurosawa K, Plassmeier J, Kalinowski J, Rückert C, Sinskey AJ.

Metab Eng. 2015 Jul;30:89-95. doi: 10.1016/j.ymben.2015.04.006. Epub 2015 May 1.

PMID:
25936337
17.

Improved glycerol utilization by a triacylglycerol-producing Rhodococcus opacus strain for renewable fuels.

Kurosawa K, Radek A, Plassmeier JK, Sinskey AJ.

Biotechnol Biofuels. 2015 Feb 26;8:31. doi: 10.1186/s13068-015-0209-z. eCollection 2015.

18.

Characterization and modification of enzymes in the 2-ketoisovalerate biosynthesis pathway of Ralstonia eutropha H16.

Lu J, Brigham CJ, Plassmeier JK, Sinskey AJ.

Appl Microbiol Biotechnol. 2015 Jan;99(2):761-74. doi: 10.1007/s00253-014-5965-3. Epub 2014 Aug 1.

PMID:
25081555
19.

Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P(HB-co-HHx)) from butyrate using engineered Ralstonia eutropha.

Jeon JM, Brigham CJ, Kim YH, Kim HJ, Yi DH, Kim H, Rha C, Sinskey AJ, Yang YH.

Appl Microbiol Biotechnol. 2014 Jun;98(12):5461-9. doi: 10.1007/s00253-014-5617-7. Epub 2014 Mar 11.

PMID:
24615385
20.

Isopropanol production with engineered Cupriavidus necator as bioproduction platform.

Grousseau E, Lu J, Gorret N, Guillouet SE, Sinskey AJ.

Appl Microbiol Biotechnol. 2014 May;98(9):4277-90. doi: 10.1007/s00253-014-5591-0. Epub 2014 Mar 7.

PMID:
24604499
21.

Insights into bacterial CO2 metabolism revealed by the characterization of four carbonic anhydrases in Ralstonia eutropha H16.

Gai CS, Lu J, Brigham CJ, Bernardi AC, Sinskey AJ.

AMB Express. 2014 Jan 10;4(1):2. doi: 10.1186/2191-0855-4-2.

22.

The Rhodococcus opacus TadD protein mediates triacylglycerol metabolism by regulating intracellular NAD(P)H pools.

MacEachran DP, Sinskey AJ.

Microb Cell Fact. 2013 Nov 9;12:104. doi: 10.1186/1475-2859-12-104.

23.

Engineering xylose metabolism in triacylglycerol-producing Rhodococcus opacus for lignocellulosic fuel production.

Kurosawa K, Wewetzer SJ, Sinskey AJ.

Biotechnol Biofuels. 2013 Sep 16;6(1):134. doi: 10.1186/1754-6834-6-134.

24.

Molecular MRI of collagen to diagnose and stage liver fibrosis.

Fuchs BC, Wang H, Yang Y, Wei L, Polasek M, Schühle DT, Lauwers GY, Parkar A, Sinskey AJ, Tanabe KK, Caravan P.

J Hepatol. 2013 Nov;59(5):992-8. doi: 10.1016/j.jhep.2013.06.026. Epub 2013 Jul 6.

25.

Microparticles prepared from biodegradable polyhydroxyalkanoates as matrix for encapsulation of cytostatic drug.

Murueva AV, Shishatskaya EI, Kuzmina AM, Volova TG, Sinskey AJ.

J Mater Sci Mater Med. 2013 Aug;24(8):1905-15. doi: 10.1007/s10856-013-4941-2. Epub 2013 May 15.

PMID:
23674057
26.

Effects of intracellular poly(3-hydroxybutyrate) reserves on physiological-biochemical properties and growth of Ralstonia eutropha.

Volova TG, Zhila NO, Kalacheva GS, Brigham CJ, Sinskey AJ.

Res Microbiol. 2013 Feb-Mar;164(2):164-71. doi: 10.1016/j.resmic.2012.10.008. Epub 2012 Oct 23.

PMID:
23089257
27.

Manipulation of Ralstonia eutropha carbon storage pathways to produce useful bio-based products.

Brigham CJ, Zhila N, Shishatskaya E, Volova TG, Sinskey AJ.

Subcell Biochem. 2012;64:343-66. doi: 10.1007/978-94-007-5055-5_17. Review.

PMID:
23080259
28.

Whole-genome microarray and gene deletion studies reveal regulation of the polyhydroxyalkanoate production cycle by the stringent response in Ralstonia eutropha H16.

Brigham CJ, Speth DR, Rha C, Sinskey AJ.

Appl Environ Microbiol. 2012 Nov;78(22):8033-44. doi: 10.1128/AEM.01693-12. Epub 2012 Sep 7. Erratum in: Appl Environ Microbiol. 2017 Jul 17;83(15):.

29.

Recovery of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from Ralstonia eutropha cultures with non-halogenated solvents.

Riedel SL, Brigham CJ, Budde CF, Bader J, Rha C, Stahl U, Sinskey AJ.

Biotechnol Bioeng. 2013 Feb;110(2):461-70. doi: 10.1002/bit.24713. Epub 2012 Sep 24.

PMID:
22903730
30.

Studies on the production of branched-chain alcohols in engineered Ralstonia eutropha.

Lu J, Brigham CJ, Gai CS, Sinskey AJ.

Appl Microbiol Biotechnol. 2012 Oct;96(1):283-97. doi: 10.1007/s00253-012-4320-9. Epub 2012 Aug 4.

PMID:
22864971
31.

Biosynthesis and characterization of polyhydroxyalkanoate containing high 3-hydroxyhexanoate monomer fraction from crude palm kernel oil by recombinant Cupriavidus necator.

Wong YM, Brigham CJ, Rha C, Sinskey AJ, Sudesh K.

Bioresour Technol. 2012 Oct;121:320-7. doi: 10.1016/j.biortech.2012.07.015. Epub 2012 Jul 16.

PMID:
22858502
32.

Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) containing a predominant amount of 3-hydroxyvalerate by engineered Escherichia coli expressing propionate-CoA transferase.

Yang YH, Brigham CJ, Song E, Jeon JM, Rha CK, Sinskey AJ.

J Appl Microbiol. 2012 Oct;113(4):815-23. doi: 10.1111/j.1365-2672.2012.05391.x. Epub 2012 Aug 2.

33.

Characterization of an extracellular lipase and its chaperone from Ralstonia eutropha H16.

Lu J, Brigham CJ, Rha C, Sinskey AJ.

Appl Microbiol Biotechnol. 2013 Mar;97(6):2443-54. doi: 10.1007/s00253-012-4115-z. Epub 2012 May 16.

PMID:
22588499
34.

Examination of PHB Depolymerases in Ralstonia eutropha: Further Elucidation of the Roles of Enzymes in PHB Homeostasis.

Brigham CJ, Reimer EN, Rha C, Sinskey AJ.

AMB Express. 2012 Apr 26;2(1):26. doi: 10.1186/2191-0855-2-26.

35.

Purification of polyhydroxybutyrate synthase from its native organism, Ralstonia eutropha: implications for the initiation and elongation of polymer formation in vivo.

Cho M, Brigham CJ, Sinskey AJ, Stubbe J.

Biochemistry. 2012 Mar 20;51(11):2276-88. doi: 10.1021/bi2013596. Epub 2012 Mar 7.

36.

[Synthesis of 3-hydroxybutyrate-CO-4-hydroxybutyrate copolymers by hydrogen-oxidizing bacteria].

Volova TG, Zhila NO, Kalacheva GS, Sokolenko VA, Sinskey AJ.

Prikl Biokhim Mikrobiol. 2011 Sep-Oct;47(5):544-50. Russian.

PMID:
22232895
37.

Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production.

Song Y, Matsumoto K, Yamada M, Gohda A, Brigham CJ, Sinskey AJ, Taguchi S.

Appl Microbiol Biotechnol. 2012 Mar;93(5):1917-25. doi: 10.1007/s00253-011-3718-0. Epub 2011 Nov 30.

38.

Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development.

Holder JW, Ulrich JC, DeBono AC, Godfrey PA, Desjardins CA, Zucker J, Zeng Q, Leach AL, Ghiviriga I, Dancel C, Abeel T, Gevers D, Kodira CD, Desany B, Affourtit JP, Birren BW, Sinskey AJ.

PLoS Genet. 2011 Sep;7(9):e1002219. doi: 10.1371/journal.pgen.1002219. Epub 2011 Sep 8.

39.

Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by Ralstonia eutropha in high cell density palm oil fermentations.

Riedel SL, Bader J, Brigham CJ, Budde CF, Yusof ZA, Rha C, Sinskey AJ.

Biotechnol Bioeng. 2012 Jan;109(1):74-83. doi: 10.1002/bit.23283. Epub 2011 Aug 18.

PMID:
21809332
40.

Oil palm vegetation liquor: a new source of phenolic bioactives.

Sambanthamurthi R, Tan Y, Sundram K, Abeywardena M, Sambandan TG, Rha C, Sinskey AJ, Subramaniam K, Leow SS, Hayes KC, Wahid MB.

Br J Nutr. 2011 Dec;106(11):1655-63. doi: 10.1017/S0007114511002121. Epub 2011 Jun 6.

41.

Positive outcomes of oil palm phenolics on degenerative diseases in animal models.

Sambanthamurthi R, Tan Y, Sundram K, Hayes KC, Abeywardena M, Leow SS, Sekaran SD, Sambandan TG, Rha C, Sinskey AJ, Subramaniam K, Fairus S, Wahid MB.

Br J Nutr. 2011 Dec;106(11):1664-75. doi: 10.1017/S0007114511002133. Epub 2011 Jun 7.

42.

Microfluidic chemostat and turbidostat with flow rate, oxygen, and temperature control for dynamic continuous culture.

Lee KS, Boccazzi P, Sinskey AJ, Ram RJ.

Lab Chip. 2011 May 21;11(10):1730-9. doi: 10.1039/c1lc20019d. Epub 2011 Mar 29.

PMID:
21445442
43.

Characterization of the highly active polyhydroxyalkanoate synthase of Chromobacterium sp. strain USM2.

Bhubalan K, Chuah JA, Shozui F, Brigham CJ, Taguchi S, Sinskey AJ, Rha C, Sudesh K.

Appl Environ Microbiol. 2011 May;77(9):2926-33. doi: 10.1128/AEM.01997-10. Epub 2011 Mar 11.

44.

Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from plant oil by engineered Ralstonia eutropha strains.

Budde CF, Riedel SL, Willis LB, Rha C, Sinskey AJ.

Appl Environ Microbiol. 2011 May;77(9):2847-54. doi: 10.1128/AEM.02429-10. Epub 2011 Mar 11.

45.

Growth and polyhydroxybutyrate production by Ralstonia eutropha in emulsified plant oil medium.

Budde CF, Riedel SL, Hübner F, Risch S, Popović MK, Rha C, Sinskey AJ.

Appl Microbiol Biotechnol. 2011 Mar;89(5):1611-9. doi: 10.1007/s00253-011-3102-0. Epub 2011 Jan 29.

PMID:
21279345
46.

The Rhodococcus opacus PD630 heparin-binding hemagglutinin homolog TadA mediates lipid body formation.

MacEachran DP, Prophete ME, Sinskey AJ.

Appl Environ Microbiol. 2010 Nov;76(21):7217-25. doi: 10.1128/AEM.00985-10. Epub 2010 Sep 17.

47.

Antibiotic biosynthesis following horizontal gene transfer: new milestone for novel natural product discovery?

Kurosawa K, Maceachran DP, Sinskey AJ.

Expert Opin Drug Discov. 2010 Sep;5(9):819-25. doi: 10.1517/17460441.2010.505599. Epub 2010 Jul 15.

PMID:
22823257
48.

Roles of multiple acetoacetyl coenzyme A reductases in polyhydroxybutyrate biosynthesis in Ralstonia eutropha H16.

Budde CF, Mahan AE, Lu J, Rha C, Sinskey AJ.

J Bacteriol. 2010 Oct;192(20):5319-28. doi: 10.1128/JB.00207-10. Epub 2010 Aug 20.

49.

Elucidation of beta-oxidation pathways in Ralstonia eutropha H16 by examination of global gene expression.

Brigham CJ, Budde CF, Holder JW, Zeng Q, Mahan AE, Rha C, Sinskey AJ.

J Bacteriol. 2010 Oct;192(20):5454-64. doi: 10.1128/JB.00493-10. Epub 2010 Aug 13.

50.

Optimization of growth media components for polyhydroxyalkanoate (PHA) production from organic acids by Ralstonia eutropha.

Yang YH, Brigham CJ, Budde CF, Boccazzi P, Willis LB, Hassan MA, Yusof ZA, Rha C, Sinskey AJ.

Appl Microbiol Biotechnol. 2010 Aug;87(6):2037-45. doi: 10.1007/s00253-010-2699-8. Epub 2010 Jun 10.

PMID:
20535466

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