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Items: 12


ENPP1 enzyme replacement therapy improves blood pressure and cardiovascular function in a mouse model of generalized arterial calcification of infancy.

Khan T, Sinkevicius KW, Vong S, Avakian A, Leavitt MC, Malanson H, Marozsan A, Askew KL.

Dis Model Mech. 2018 Oct 8;11(10). pii: dmm035691. doi: 10.1242/dmm.035691.


RNaseT2 knockout rats exhibit hippocampal neuropathology and deficits in memory.

Sinkevicius KW, Morrison TR, Kulkarni P, Caffrey Cagliostro MK, Iriah S, Malmberg S, Sabrick J, Honeycutt JA, Askew KL, Trivedi M, Ferris CF.

Dis Model Mech. 2018 Jun 27;11(6). pii: dmm032631. doi: 10.1242/dmm.032631.


E-Cadherin Loss Accelerates Tumor Progression and Metastasis in a Mouse Model of Lung Adenocarcinoma.

Sinkevicius KW, Bellaria KJ, Barrios J, Pessina P, Gupta M, Brainson CF, Bronson RT, Kim CF.

Am J Respir Cell Mol Biol. 2018 Aug;59(2):237-245. doi: 10.1165/rcmb.2017-0210OC.


Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.

Sinkevicius KW, Kriegel C, Bellaria KJ, Lee J, Lau AN, Leeman KT, Zhou P, Beede AM, Fillmore CM, Caswell D, Barrios J, Wong KK, Sholl LM, Schlaeger TM, Bronson RT, Chirieac LR, Winslow MM, Haigis MC, Kim CF.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10299-304. doi: 10.1073/pnas.1404399111. Epub 2014 Jun 30.


Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis.

Lau AN, Curtis SJ, Fillmore CM, Rowbotham SP, Mohseni M, Wagner DE, Beede AM, Montoro DT, Sinkevicius KW, Walton ZE, Barrios J, Weiss DJ, Camargo FD, Wong KK, Kim CF.

EMBO J. 2014 Mar 3;33(5):468-81. doi: 10.1002/embj.201386082. Epub 2014 Feb 4. Erratum in: EMBO J. 2014 Jul 1;33(13):1502.


Prolactin activates ERĪ± in the absence of ligand in female mammary development and carcinogenesis in vivo.

O'Leary KA, Jallow F, Rugowski DE, Sullivan R, Sinkevicius KW, Greene GL, Schuler LA.

Endocrinology. 2013 Dec;154(12):4483-92. doi: 10.1210/en.2013-1533. Epub 2013 Sep 24.


Primary tumor genotype is an important determinant in identification of lung cancer propagating cells.

Curtis SJ, Sinkevicius KW, Li D, Lau AN, Roach RR, Zamponi R, Woolfenden AE, Kirsch DG, Wong KK, Kim CF.

Cell Stem Cell. 2010 Jul 2;7(1):127-33. doi: 10.1016/j.stem.2010.05.021.


Characterization of the ovarian and reproductive abnormalities in prepubertal and adult estrogen non-responsive estrogen receptor alpha knock-in (ENERKI) mice.

Sinkevicius KW, Woloszyn K, Laine M, Jackson KS, Greene GL, Woodruff TK, Burdette JE.

Steroids. 2009 Nov;74(12):913-9. doi: 10.1016/j.steroids.2009.06.012. Epub 2009 Jul 23.


Estrogen-dependent and -independent estrogen receptor-alpha signaling separately regulate male fertility.

Sinkevicius KW, Laine M, Lotan TL, Woloszyn K, Richburg JH, Greene GL.

Endocrinology. 2009 Jun;150(6):2898-905. doi: 10.1210/en.2008-1016. Epub 2009 Mar 5.


Stem cell biology in the lung and lung cancers: using pulmonary context and classic approaches.

Raiser DM, Zacharek SJ, Roach RR, Curtis SJ, Sinkevicius KW, Gludish DW, Kim CF.

Cold Spring Harb Symp Quant Biol. 2008;73:479-90. doi: 10.1101/sqb.2008.73.036. Epub 2008 Nov 21. Review.


An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo.

Sinkevicius KW, Burdette JE, Woloszyn K, Hewitt SC, Hamilton K, Sugg SL, Temple KA, Wondisford FE, Korach KS, Woodruff TK, Greene GL.

Endocrinology. 2008 Jun;149(6):2970-9. doi: 10.1210/en.2007-1526. Epub 2008 Mar 13.


The homeobox gene GLABRA2 affects seed oil content in Arabidopsis.

Shen B, Sinkevicius KW, Selinger DA, Tarczynski MC.

Plant Mol Biol. 2006 Feb;60(3):377-87.


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