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Items: 1 to 50 of 216

1.

Phase II Randomized, Double-Masked, Vehicle-Controlled Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis.

Bonini S, Lambiase A, Rama P, Sinigaglia F, Allegretti M, Chao W, Mantelli F; REPARO Study Group.

Ophthalmology. 2018 Sep;125(9):1332-1343. doi: 10.1016/j.ophtha.2018.02.022. Epub 2018 Apr 10.

2.

Impact of diabetes on fibrinogen levels and its relationship with platelet reactivity and coronary artery disease: A single-centre study.

Di Giovine G, Verdoia M, Barbieri L, Schaffer A, Aimaretti G, Bellomo G, Marino P, Suryapranata H, Sinigaglia F, De Luca G; Novara Atherosclerosis Study (NAS) group.

Diabetes Res Clin Pract. 2015 Sep;109(3):541-50. doi: 10.1016/j.diabres.2015.05.038. Epub 2015 May 18.

PMID:
26163440
3.

Homocysteine Levels Influence Platelet Reactivity in Coronary Artery Disease Patients Treated With Acetylsalicylic Acid.

Verdoia M, Schaffer A, Pergolini P, Rolla R, Barbieri L, Bellomo G, Sinigaglia F, Marino P, Suryapranata H, De Luca G; Novara Atherosclerosis Study Group (NAS).

J Cardiovasc Pharmacol. 2015 Jul;66(1):35-40. doi: 10.1097/FJC.0000000000000240.

PMID:
25714593
4.

Impact of diabetes on neutrophil-to-lymphocyte ratio and its relationship to coronary artery disease.

Verdoia M, Schaffer A, Barbieri L, Aimaretti G, Marino P, Sinigaglia F, Suryapranata H, De Luca G; Novara Atherosclerosis Study Group (NAS).

Diabetes Metab. 2015 Sep;41(4):304-11. doi: 10.1016/j.diabet.2015.01.001. Epub 2015 Feb 2.

PMID:
25656745
5.

Impact of age on mean platelet volume and its relationship with coronary artery disease: a single-centre cohort study.

Verdoia M, Schaffer A, Barbieri L, Bellomo G, Marino P, Sinigaglia F, Suryapranata H, De Luca G; Novara Atherosclerosis Study (NAS) group.

Exp Gerontol. 2015 Feb;62:32-6. doi: 10.1016/j.exger.2014.12.019. Epub 2015 Jan 3.

PMID:
25562813
6.

Eosinophils count and periprocedural myocardial infarction in patients undergoing percutaneous coronary interventions.

Verdoia M, Schaffer A, Barbieri L, Sinigaglia F, Marino P, Suryapranata H, De Luca G; Novara Atherosclerosis Study Group (NAS).

Atherosclerosis. 2014 Sep;236(1):169-74. doi: 10.1016/j.atherosclerosis.2014.06.023. Epub 2014 Jul 11.

PMID:
25055060
7.

The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness.

Rainero E, Cianflone C, Porporato PE, Chianale F, Malacarne V, Bettio V, Ruffo E, Ferrara M, Benecchia F, Capello D, Paster W, Locatelli I, Bertoni A, Filigheddu N, Sinigaglia F, Norman JC, Baldanzi G, Graziani A.

PLoS One. 2014 Jun 2;9(6):e97144. doi: 10.1371/journal.pone.0097144. eCollection 2014.

8.

Impact of diabetes on uric acid and its relationship with the extent of coronary artery disease and platelet aggregation: a single-centre cohort study.

Verdoia M, Barbieri L, Schaffer A, Cassetti E, Nardin M, Bellomo G, Aimaretti G, Marino P, Sinigaglia F, De Luca G; Novara Atherosclerosis Study Group (NAS).

Metabolism. 2014 May;63(5):640-6. doi: 10.1016/j.metabol.2014.01.010. Epub 2014 Jan 29.

PMID:
24606806
9.

Relationship between glycoprotein IIIa platelet receptor gene polymorphism and coronary artery disease.

Verdoia M, Cassetti E, Schaffer A, Barbieri L, Giovine GD, Nardin M, Marino P, Sinigaglia F, Luca GD; Novara Atherosclerosis Study Group (NAS).

Angiology. 2015 Jan;66(1):79-85. doi: 10.1177/0003319714524296. Epub 2014 Feb 28.

PMID:
24586027
10.

Diabetes, glucose control and mean platelet volume: a single-centre cohort study.

Verdoia M, Schaffer A, Barbieri L, Cassetti E, Nardin M, Bellomo G, Marino P, Sinigaglia F, De Luca G; Novara Atherosclerosis Study (NAS) group.

Diabetes Res Clin Pract. 2014 May;104(2):288-94. doi: 10.1016/j.diabres.2013.12.020. Epub 2014 Jan 17.

PMID:
24530116
11.

Platelet PIA1/PIA2 polymorphism and the risk of periprocedural myocardial infarction in patients with acute coronary syndromes undergoing coronary angioplasty.

Verdoia M, Secco GG, Cassetti E, Schaffer A, Barbieri L, Perrone-Filardi P, Marino P, Suryapranata H, Sinigaglia F, De Luca G.

Blood Coagul Fibrinolysis. 2014 Mar;25(2):107-13. doi: 10.1097/MBC.0b013e3283650717.

PMID:
24480844
12.

Benefits from new ADP antagonists as compared with clopidogrel in patients with stable angina or acute coronary syndrome undergoing invasive management: a meta-analysis of randomized trials.

Verdoia M, Schaffer A, Barbieri L, Cassetti E, Piccolo R, Galasso G, Marino P, Sinigaglia F, De Luca G.

J Cardiovasc Pharmacol. 2014 Apr;63(4):339-50. doi: 10.1097/FJC.0000000000000052. Review.

PMID:
24336016
13.

Safety and pharmacokinetics of escalating doses of human recombinant nerve growth factor eye drops in a double-masked, randomized clinical trial.

Ferrari MP, Mantelli F, Sacchetti M, Antonangeli MI, Cattani F, D'Anniballe G, Sinigaglia F, Ruffini PA, Lambiase A.

BioDrugs. 2014 Jun;28(3):275-83. doi: 10.1007/s40259-013-0079-5.

14.

Platelet-larger cell ratio and the risk of periprocedural myocardial infarction after percutaneous coronary revascularization.

Verdoia M, Barbieri L, Schaffer A, Cassetti E, Marino P, Bellomo G, Sinigaglia F, De Luca G; Novara Atherosclerosis Study Group (NAS).

Heart Vessels. 2015 Jan;30(1):20-7. doi: 10.1007/s00380-013-0449-4. Epub 2013 Dec 3.

PMID:
24297745
15.

Platelet HPA-1 a/HPA-1 b polymorphism and the risk of periprocedural myocardial infarction in patients undergoing elective PCI.

Verdoia M, Secco GG, Barbieri L, Cassetti E, Schaffer A, Sinigaglia F, Marino P, Suryapranata H, De Luca G; Novara Atherosreclerosis Study Group (NAS).

Platelets. 2014;25(5):367-72. doi: 10.3109/09537104.2013.821602. Epub 2013 Nov 27.

PMID:
24283589
16.

A diet supplemented with ALA-rich flaxseed prevents cardiomyocyte apoptosis by regulating caveolin-3 expression.

Carotenuto F, Minieri M, Monego G, Fiaccavento R, Bertoni A, Sinigaglia F, Vecchini A, Carosella L, Di Nardo P.

Cardiovasc Res. 2013 Dec 1;100(3):422-31. doi: 10.1093/cvr/cvt211. Epub 2013 Sep 16.

PMID:
24042018
17.

Platelet distribution width and the risk of periprocedural myocardial infarction in patients undergoing percutaneous coronary intervention.

Verdoia M, Barbieri L, Schaffer A, Cassetti E, Di Giovine G, Bellomo G, Marino P, Sinigaglia F, De Luca G.

J Thromb Thrombolysis. 2014 Apr;37(3):345-52. doi: 10.1007/s11239-013-0954-4.

PMID:
23793523
18.

Mean platelet volume is not associated with platelet reactivity and the extent of coronary artery disease in diabetic patients.

De Luca G, Verdoia M, Cassetti E, Schaffer A, Di Giovine G, Bertoni A, Di Vito C, Sampietro S, Aimaretti G, Bellomo G, Marino P, Sinigaglia F; Novara Atherosclerosis Study (NAS) group.

Blood Coagul Fibrinolysis. 2013 Sep;24(6):619-24. doi: 10.1097/MBC.0b013e328360c75a.

PMID:
23689272
19.

Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice.

Porporato PE, Filigheddu N, Reano S, Ferrara M, Angelino E, Gnocchi VF, Prodam F, Ronchi G, Fagoonee S, Fornaro M, Chianale F, Baldanzi G, Surico N, Sinigaglia F, Perroteau I, Smith RG, Sun Y, Geuna S, Graziani A.

J Clin Invest. 2013 Feb;123(2):611-22. doi: 10.1172/JCI39920. Epub 2013 Jan 2.

20.

The phytoestrogen 8-prenylnaringenin inhibits agonist-dependent activation of human platelets.

Di Vito C, Bertoni A, Nalin M, Sampietro S, Zanfa M, Sinigaglia F.

Biochim Biophys Acta. 2012 Nov;1820(11):1724-33. doi: 10.1016/j.bbagen.2012.06.018. Epub 2012 Jul 3.

PMID:
22766195
21.

Alterations of negative regulators of cytokine signalling in immunodeficiency-related non-Hodgkin lymphoma.

Capello D, Gloghini A, Baldanzi G, Martini M, Deambrogi C, Lucioni M, Piranda D, Famà R, Graziani A, Spina M, Tirelli U, Paulli M, Larocca LM, Gaidano G, Carbone A, Sinigaglia F.

Hematol Oncol. 2013 Mar;31(1):22-8. doi: 10.1002/hon.2010. Epub 2012 Apr 9.

PMID:
22488585
22.

Dehydroepiandrosterone-sulfate inhibits thrombin-induced platelet aggregation.

Bertoni A, Rastoldo A, Sarasso C, Di Vito C, Sampietro S, Nalin M, Bagarotti A, Sinigaglia F.

Steroids. 2012 Feb;77(3):260-8. doi: 10.1016/j.steroids.2011.12.010. Epub 2011 Dec 13.

PMID:
22182832
23.

SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling.

Baldanzi G, Pighini A, Bettio V, Rainero E, Traini S, Chianale F, Porporato PE, Filigheddu N, Mesturini R, Song S, Schweighoffer T, Patrussi L, Baldari CT, Zhong XP, van Blitterswijk WJ, Sinigaglia F, Nichols KE, Rubio I, Parolini O, Graziani A.

J Immunol. 2011 Dec 1;187(11):5941-51. doi: 10.4049/jimmunol.1002476. Epub 2011 Nov 2.

24.

Activation of human platelets by 2-arachidonoylglycerol: role of PKC in NO/cGMP pathway modulation.

Signorello MG, Giacobbe E, Segantin A, Avigliano L, Sinigaglia F, Maccarrone M, Leoncini G.

Curr Neurovasc Res. 2011 Aug 1;8(3):200-9.

PMID:
21675954
25.

Mutations of CD79A, CD79B and EZH2 genes in immunodeficiency-related non-Hodgkin lymphomas.

Capello D, Gloghini A, Martini M, Spina M, Tirelli U, Bertoni F, Rinaldi A, Morra E, Rambaldi A, Sinigaglia F, Larocca LM, Carbone A.

Br J Haematol. 2011 Mar;152(6):777-80. doi: 10.1111/j.1365-2141.2010.08445.x. Epub 2011 Jan 30. No abstract available.

PMID:
21275949
26.

Human platelets express authentic CB₁ and CB₂ receptors.

Catani MV, Gasperi V, Catanzaro G, Baldassarri S, Bertoni A, Sinigaglia F, Avigliano L, Maccarrone M.

Curr Neurovasc Res. 2010 Nov;7(4):311-8.

PMID:
20854251
27.

Diacylglycerol kinase alpha mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI.

Chianale F, Rainero E, Cianflone C, Bettio V, Pighini A, Porporato PE, Filigheddu N, Serini G, Sinigaglia F, Baldanzi G, Graziani A.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4182-7. doi: 10.1073/pnas.0908326107. Epub 2010 Feb 16.

28.

The oestrogen receptor GPER is expressed in human haematopoietic stem cells but not in mature megakaryocytes.

Di Vito C, Bergante S, Balduini A, Rastoldo A, Bagarotti A, Surico N, Bertoni A, Sinigaglia F.

Br J Haematol. 2010 Apr;149(1):150-2. doi: 10.1111/j.1365-2141.2009.08028.x. Epub 2009 Dec 8. No abstract available.

PMID:
19995393
29.

Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol.

Catani MV, Fezza F, Baldassarri S, Gasperi V, Bertoni A, Pasquariello N, Finazzi-Agrò A, Sinigaglia F, Avigliano L, Maccarrone M.

J Mol Med (Berl). 2009 Jan;87(1):65-74. doi: 10.1007/s00109-008-0406-3. Epub 2008 Sep 27.

PMID:
18820887
30.

The endocannabinoid 2-arachidonoylglycerol activates human platelets through non-CB1/CB2 receptors.

Baldassarri S, Bertoni A, Bagarotti A, Sarasso C, Zanfa M, Catani MV, Avigliano L, Maccarrone M, Torti M, Sinigaglia F.

J Thromb Haemost. 2008 Oct;6(10):1772-9. doi: 10.1111/j.1538-7836.2008.03093.x. Epub 2008 Jul 19.

31.

Diacylglycerol kinase-alpha mediates hepatocyte growth factor-induced epithelial cell scatter by regulating Rac activation and membrane ruffling.

Chianale F, Cutrupi S, Rainero E, Baldanzi G, Porporato PE, Traini S, Filigheddu N, Gnocchi VF, Santoro MM, Parolini O, van Blitterswijk WJ, Sinigaglia F, Graziani A.

Mol Biol Cell. 2007 Dec;18(12):4859-71. Epub 2007 Sep 26.

32.

Diacylglycerol kinase-alpha phosphorylation by Src on Y335 is required for activation, membrane recruitment and Hgf-induced cell motility.

Baldanzi G, Cutrupi S, Chianale F, Gnocchi V, Rainero E, Porporato P, Filigheddu N, van Blitterswijk WJ, Parolini O, Bussolino F, Sinigaglia F, Graziani A.

Oncogene. 2008 Feb 7;27(7):942-56. Epub 2007 Aug 13.

PMID:
17700527
33.

Membrane lipid rafts coordinate estrogen-dependent signaling in human platelets.

Reineri S, Bertoni A, Sanna E, Baldassarri S, Sarasso C, Zanfa M, Canobbio I, Torti M, Sinigaglia F.

Biochim Biophys Acta. 2007 Feb;1773(2):273-8. Epub 2006 Dec 8.

34.

Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells.

Filigheddu N, Gnocchi VF, Coscia M, Cappelli M, Porporato PE, Taulli R, Traini S, Baldanzi G, Chianale F, Cutrupi S, Arnoletti E, Ghè C, Fubini A, Surico N, Sinigaglia F, Ponzetto C, Muccioli G, Crepaldi T, Graziani A.

Mol Biol Cell. 2007 Mar;18(3):986-94. Epub 2007 Jan 3.

35.

Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2).

Sironi M, Martinez FO, D'Ambrosio D, Gattorno M, Polentarutti N, Locati M, Gregorio A, Iellem A, Cassatella MA, Van Damme J, Sozzani S, Martini A, Sinigaglia F, Vecchi A, Mantovani A.

J Leukoc Biol. 2006 Aug;80(2):342-9. Epub 2006 May 30.

PMID:
16735693
36.

Cutting Edge: Inhibition of the retinoid X receptor (RXR) blocks T helper 2 differentiation and prevents allergic lung inflammation.

Grenningloh R, Gho A, di Lucia P, Klaus M, Bollag W, Ho IC, Sinigaglia F, Panina-Bordignon P.

J Immunol. 2006 May 1;176(9):5161-6.

37.

Met identification on human platelets: role of hepatocyte growth factor in the modulation of platelet activation.

Pietrapiana D, Sala M, Prat M, Sinigaglia F.

FEBS Lett. 2005 Aug 15;579(20):4550-4.

38.

T cell epitope characterization in tandemly repetitive Trypanosoma cruzi B13 protein.

Abel LC, Iwai LK, Viviani W, Bilate AM, Faé KC, Ferreira RC, Goldberg AC, Juliano L, Juliano MA, Ianni B, Mady C, Gruber A, Hammer J, Sinigaglia F, Kalil J, Cunha-Neto E.

Microbes Infect. 2005 Aug-Sep;7(11-12):1184-95.

PMID:
15951215
39.

Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation.

Campus F, Lova P, Bertoni A, Sinigaglia F, Balduini C, Torti M.

J Biol Chem. 2005 Jul 1;280(26):24386-95. Epub 2005 Apr 29.

40.

Activation of the small GTPase Rap2B in agonist-stimulated human platelets.

Greco F, Sinigaglia F, Balduini C, Torti M.

J Thromb Haemost. 2004 Dec;2(12):2223-30.

41.

Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia.

Sessa G, Podini P, Mariani M, Meroni A, Spreafico R, Sinigaglia F, Colonna M, Panina P, Meldolesi J.

Eur J Neurosci. 2004 Nov;20(10):2617-28.

PMID:
15548205
42.

Triggering receptor expressed on myeloid cells: role in the diagnosis of lung infections.

Richeldi L, Mariani M, Losi M, Maselli F, Corbetta L, Buonsanti C, Colonna M, Sinigaglia F, Panina-Bordignon P, Fabbri LM.

Eur Respir J. 2004 Aug;24(2):247-50.

43.

Nongenomic effects of 17beta-estradiol in human platelets: potentiation of thrombin-induced aggregation through estrogen receptor beta and Src kinase.

Moro L, Reineri S, Piranda D, Pietrapiana D, Lova P, Bertoni A, Graziani A, Defilippi P, Canobbio I, Torti M, Sinigaglia F.

Blood. 2005 Jan 1;105(1):115-21. Epub 2004 Jun 15.

PMID:
15198955
44.

Activation of diacylglycerol kinase alpha is required for VEGF-induced angiogenic signaling in vitro.

Baldanzi G, Mitola S, Cutrupi S, Filigheddu N, van Blitterswijk WJ, Sinigaglia F, Bussolino F, Graziani A.

Oncogene. 2004 Jun 17;23(28):4828-38.

PMID:
15122338
45.

Contribution of protease-activated receptors 1 and 4 and glycoprotein Ib-IX-V in the G(i)-independent activation of platelet Rap1B by thrombin.

Lova P, Campus F, Lombardi R, Cattaneo M, Sinigaglia F, Balduini C, Torti M.

J Biol Chem. 2004 Jun 11;279(24):25299-306. Epub 2004 Apr 12.

46.

A role for p38 MAP kinase in platelet activation by von Willebrand factor.

Canobbio I, Reineri S, Sinigaglia F, Balduini C, Torti M.

Thromb Haemost. 2004 Jan;91(1):102-10.

PMID:
14691575
47.

Increased expression of alpha(1,3)-fucosyltransferase-VII and P-selectin binding of synovial fluid T cells in juvenile idiopathic arthritis.

De Benedetti F, Pignatti P, Biffi M, Bono E, Wahid S, Ingegnoli F, Chang SY, Alexander H, Massa M, Pistorio A, Martini A, Pitzalis C, Sinigaglia F, Rogge L.

J Rheumatol. 2003 Jul;30(7):1611-5.

PMID:
12858466
48.

Special attractions for suppressor T cells.

D'Ambrosio D, Sinigaglia F, Adorini L.

Trends Immunol. 2003 Mar;24(3):122-6. Review. No abstract available.

PMID:
12615206
49.

Chemokine receptors in inflammation: an overview.

D'Ambrosio D, Panina-Bordignon P, Sinigaglia F.

J Immunol Methods. 2003 Feb;273(1-2):3-13. Review.

PMID:
12535793
50.

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT.

Baldanzi G, Filigheddu N, Cutrupi S, Catapano F, Bonissoni S, Fubini A, Malan D, Baj G, Granata R, Broglio F, Papotti M, Surico N, Bussolino F, Isgaard J, Deghenghi R, Sinigaglia F, Prat M, Muccioli G, Ghigo E, Graziani A.

J Cell Biol. 2002 Dec 23;159(6):1029-37. Epub 2002 Dec 16.

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