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Items: 1 to 50 of 95

1.

Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion.

Clark DJ, McMillan LE, Tan SL, Bellomo G, Massoue C, Thompson H, Mykhaylechko L, Alibhai D, Ruan X, Singleton KL, Du M, Hedges A, Schwartzberg PL, Verkade P, Murphy RF, Wülfing C.

Elife. 2019 Oct 30;8. pii: e45789. doi: 10.7554/eLife.45789.

2.

A Deep Convolutional Neural Network for Annotation of Magnetic Resonance Imaging Sequence Type.

Ranjbar S, Singleton KW, Jackson PR, Rickertsen CR, Whitmire SA, Clark-Swanson KR, Mitchell JR, Swanson KR, Hu LS.

J Digit Imaging. 2019 Oct 25. doi: 10.1007/s10278-019-00282-4. [Epub ahead of print]

PMID:
31654174
3.

Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines.

Hinz TK, Kleczko EK, Singleton KR, Calhoun J, Marek LA, Kim J, Tan AC, Heasley LE.

Mol Pharmacol. 2019 Dec;96(6):862-870. doi: 10.1124/mol.119.117804. Epub 2019 Sep 25.

PMID:
31554698
4.

The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1.

Petermann F, Pękowska A, Johnson CA, Jankovic D, Shih HY, Jiang K, Hudson WH, Brooks SR, Sun HW, Villarino AV, Yao C, Singleton K, Akondy RS, Kanno Y, Sher A, Casellas R, Ahmed R, O'Shea JJ.

Mol Cell. 2019 Sep 19;75(6):1229-1242.e5. doi: 10.1016/j.molcel.2019.06.025. Epub 2019 Jul 31.

PMID:
31377117
5.

Integration of machine learning and mechanistic models accurately predicts variation in cell density of glioblastoma using multiparametric MRI.

Gaw N, Hawkins-Daarud A, Hu LS, Yoon H, Wang L, Xu Y, Jackson PR, Singleton KW, Baxter LC, Eschbacher J, Gonzales A, Nespodzany A, Smith K, Nakaji P, Mitchell JR, Wu T, Swanson KR, Li J.

Sci Rep. 2019 Jul 11;9(1):10063. doi: 10.1038/s41598-019-46296-4.

6.

Accurate Patient-Specific Machine Learning Models of Glioblastoma Invasion Using Transfer Learning.

Hu LS, Yoon H, Eschbacher JM, Baxter LC, Dueck AC, Nespodzany A, Smith KA, Nakaji P, Xu Y, Wang L, Karis JP, Hawkins-Daarud AJ, Singleton KW, Jackson PR, Anderies BJ, Bendok BR, Zimmerman RS, Quarles C, Porter-Umphrey AB, Mrugala MM, Sharma A, Hoxworth JM, Sattur MG, Sanai N, Koulemberis PE, Krishna C, Mitchell JR, Wu T, Tran NL, Swanson KR, Li J.

AJNR Am J Neuroradiol. 2019 Mar;40(3):418-425. doi: 10.3174/ajnr.A5981. Epub 2019 Feb 28.

7.

Zika virus infection at mid-gestation results in fetal cerebral cortical injury and fetal death in the olive baboon.

Gurung S, Reuter N, Preno A, Dubaut J, Nadeau H, Hyatt K, Singleton K, Martin A, Parks WT, Papin JF, Myers DA.

PLoS Pathog. 2019 Jan 18;15(1):e1007507. doi: 10.1371/journal.ppat.1007507. eCollection 2019 Jan.

8.

Development of national consensus statements on food labelling interpretation and protein allocation in a low phenylalanine diet for PKU.

British Inherited Metabolic Diseases Group (BIMDG) Dietitians Group, Evans S, Ford S, Adam S, Adams S, Ash J, Ashmore C, Caine G, Carruthers R, Cawtherley S, Chahal S, Clark A, Cochrane B, Daly A, Dines K, Dixon M, Dunlop C, Ellerton C, French M, Gaff L, Gingell C, Green D, Gribben J, Grimsley A, Hallam P, Hendroff U, Hill M, Hoban R, Howe S, Hunjan I, Kaalund K, Kelleher E, Khan F, Kitchen S, Lang K, Lowry S, Males J, Martin G, McStravick N, Micciche A, Newby C, Nicol C, Pereira R, Robertson L, Ross K, Simpson E, Singleton K, Skeath R, Stafford J, Terry A, Thom R, Tooke A, vanWyk K, White F, White L, MacDonald A.

Orphanet J Rare Dis. 2019 Jan 3;14(1):2. doi: 10.1186/s13023-018-0950-z.

9.

Sex differences in GBM revealed by analysis of patient imaging, transcriptome, and survival data.

Yang W, Warrington NM, Taylor SJ, Whitmire P, Carrasco E, Singleton KW, Wu N, Lathia JD, Berens ME, Kim AH, Barnholtz-Sloan JS, Swanson KR, Luo J, Rubin JB.

Sci Transl Med. 2019 Jan 2;11(473). pii: eaao5253. doi: 10.1126/scitranslmed.aao5253.

10.

ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer.

Pilling AB, Kim J, Estrada-Bernal A, Zhou Q, Le AT, Singleton KR, Heasley LE, Tan AC, DeGregori J, Doebele RC.

Oncotarget. 2018 Jan 16;9(10):8823-8835. doi: 10.18632/oncotarget.24260. eCollection 2018 Feb 6.

11.

Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence.

Singleton KR, Crawford L, Tsui E, Manchester HE, Maertens O, Liu X, Liberti MV, Magpusao AN, Stein EM, Tingley JP, Frederick DT, Boland GM, Flaherty KT, McCall SJ, Krepler C, Sproesser K, Herlyn M, Adams DJ, Locasale JW, Cichowski K, Mukherjee S, Wood KC.

Cell Rep. 2017 Dec 5;21(10):2796-2812. doi: 10.1016/j.celrep.2017.11.022.

12.

Dietary practices in propionic acidemia: A European survey.

Daly A, Pinto A, Evans S, Almeida MF, Assoun M, Belanger-Quintana A, Bernabei SM, Bollhalder S, Cassiman D, Champion H, Chan H, Dalmau J, de Boer F, de Laet C, de Meyer A, Desloovere A, Dianin A, Dixon M, Dokoupil K, Dubois S, Eyskens F, Faria A, Fasan I, Favre E, Feillet F, Fekete A, Gallo G, Gingell C, Gribben J, Kaalund Hansen K, Ter Horst NM, Jankowski C, Janssen-Regelink R, Jones I, Jouault C, Kahrs GE, Kok IL, Kowalik A, Laguerre C, Le Verge S, Lilje R, Maddalon C, Mayr D, Meyer U, Micciche A, Och U, Robert M, Rocha JC, Rogozinski H, Rohde C, Ross K, Saruggia I, Schlune A, Singleton K, Sjoqvist E, Skeath R, Stolen LH, Terry A, Timmer C, Tomlinson L, Tooke A, Vande Kerckhove K, van Dam E, van den Hurk T, van der Ploeg L, van Driessche M, van Rijn M, van Wegberg A, Vasconcelos C, Vestergaard H, Vitoria I, Webster D, White FJ, White L, Zweers H, MacDonald A.

Mol Genet Metab Rep. 2017 Oct 3;13:83-89. doi: 10.1016/j.ymgmr.2017.09.002. eCollection 2017 Dec.

13.

Gestational hypoxia disrupts the neonatal leptin surge and programs hyperphagia and obesity in male offspring in the Sprague-Dawley rat.

Vargas VE, Gurung S, Grant B, Hyatt K, Singleton K, Myers SM, Saunders D, Njoku C, Towner R, Myers DA.

PLoS One. 2017 Sep 28;12(9):e0185272. doi: 10.1371/journal.pone.0185272. eCollection 2017.

14.

A pilot replication of QUIT, a randomized controlled trial of a brief intervention for reducing risky drug use, among Latino primary care patients.

Gelberg L, Andersen RM, Rico MW, Vahidi M, Natera Rey G, Shoptaw S, Leake BD, Serota M, Singleton K, Baumeister SE.

Drug Alcohol Depend. 2017 Oct 1;179:433-440. doi: 10.1016/j.drugalcdep.2017.04.022. Epub 2017 Jun 13.

15.

Interaction Between Progesterone and Interleukin-1β in Modulating Progesterone Receptor Expression and the Inflammatory Phenotype in Human Cervical Fibroblasts.

Pierce S, Roberson AE, Hyatt K, Singleton K, Deschamps D, Myers DA.

Reprod Sci. 2018 Apr;25(4):598-608. doi: 10.1177/1933719117725826. Epub 2017 Aug 18.

PMID:
28820025
16.

Analysis of Drug Resistance Using Kinome-Wide Functional Screens.

Singleton KR, Earley KT, Heasley LE.

Methods Mol Biol. 2017;1636:163-177. doi: 10.1007/978-1-4939-7154-1_11.

PMID:
28730479
17.

Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus.

Larimore J, Zlatic SA, Arnold M, Singleton KS, Cross R, Rudolph H, Bruegge MV, Sweetman A, Garza C, Whisnant E, Faundez V.

Front Genet. 2017 Mar 10;8:28. doi: 10.3389/fgene.2017.00028. eCollection 2017.

18.

Dietary practices in isovaleric acidemia: A European survey.

Pinto A, Daly A, Evans S, Almeida MF, Assoun M, Belanger-Quintana A, Bernabei S, Bollhalder S, Cassiman D, Champion H, Chan H, Dalmau J, de Boer F, de Laet C, de Meyer A, Desloovere A, Dianin A, Dixon M, Dokoupil K, Dubois S, Eyskens F, Faria A, Fasan I, Favre E, Feillet F, Fekete A, Gallo G, Gingell C, Gribben J, Kaalund-Hansen K, Horst N, Jankowski C, Janssen-Regelink R, Jones I, Jouault C, Kahrs GE, Kok IL, Kowalik A, Laguerre C, Le Verge S, Lilje R, Maddalon C, Mayr D, Meyer U, Micciche A, Robert M, Rocha JC, Rogozinski H, Rohde C, Ross K, Saruggia I, Schlune A, Singleton K, Sjoqvist E, Stolen LH, Terry A, Timmer C, Tomlinson L, Tooke A, Vande Kerckhove K, van Dam E, van den Hurk T, van der Ploeg L, van Driessche M, van Rijn M, van Teeffelen-Heithoff A, van Wegberg A, Vasconcelos C, Vestergaard H, Vitoria I, Webster D, White FJ, White L, Zweers H, MacDonald A.

Mol Genet Metab Rep. 2017 Feb 27;12:16-22. doi: 10.1016/j.ymgmr.2017.02.001. eCollection 2017 Sep.

19.
20.

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.

Arnold M, Cross R, Singleton KS, Zlatic S, Chapleau C, Mullin AP, Rolle I, Moore CC, Theibert A, Pozzo-Miller L, Faundez V, Larimore J.

Front Cell Neurosci. 2016 Sep 22;10:218. eCollection 2016.

21.

Reduced marker of vascularization in the anterior hippocampus in a female monkey model of depression.

Kalidindi A, Kelly SD, Singleton KS, Guzman D, Merrill L, Willard SL, Shively CA, Neigh GN.

Physiol Behav. 2017 Apr 1;172:12-15. doi: 10.1016/j.physbeh.2016.07.007. Epub 2016 Jul 14.

22.

Multicenter study of nursing role complexity on environmental stressors and emotional exhaustion.

Solomon D, Singleton KA, Sun Z, Zell K, Vriezen K, Albert NM.

Appl Nurs Res. 2016 May;30:52-7. doi: 10.1016/j.apnr.2015.08.010. Epub 2015 Aug 24.

PMID:
27091253
23.

Preparing Nursing Students for Interprofessional Practice: The Interdisciplinary Curriculum for Oncology Palliative Care Education.

Hermann CP, Head BA, Black K, Singleton K.

J Prof Nurs. 2016 Jan-Feb;32(1):62-71. doi: 10.1016/j.profnurs.2015.06.001. Epub 2015 Jun 6.

24.

Gestational hypoxia modulates expression of corticotropin-releasing hormone and arginine vasopressin in the paraventricular nucleus in the ovine fetus.

Myers DA, Singleton K, Kenkel C, Kaushal KM, Ducsay CA.

Physiol Rep. 2016 Jan;4(1). pii: e12643. doi: 10.14814/phy2.12643.

25.

Project QUIT (Quit Using Drugs Intervention Trial): a randomized controlled trial of a primary care-based multi-component brief intervention to reduce risky drug use.

Gelberg L, Andersen RM, Afifi AA, Leake BD, Arangua L, Vahidi M, Singleton K, Yacenda-Murphy J, Shoptaw S, Fleming MF, Baumeister SE.

Addiction. 2015 Nov;110(11):1777-90. doi: 10.1111/add.12993.

26.

Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC.

Singleton KR, Hinz TK, Kleczko EK, Marek LA, Kwak J, Harp T, Kim J, Tan AC, Heasley LE.

Cancer Res. 2015 Oct 15;75(20):4398-406. doi: 10.1158/0008-5472.CAN-15-0509. Epub 2015 Sep 10.

27.

An Inducible TGF-β2-TGFβR Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases.

Kleczko EK, Kim J, Keysar SB, Heasley LR, Eagles JR, Simon M, Marshall ME, Singleton KR, Jimeno A, Tan AC, Heasley LE.

PLoS One. 2015 May 6;10(5):e0123600. doi: 10.1371/journal.pone.0123600. eCollection 2015.

28.

How strict is galactose restriction in adults with galactosaemia? International practice.

Adam S, Akroyd R, Bernabei S, Bollhalder S, Boocock S, Burlina A, Coote T, Corthouts K, Dalmau J, Dawson S, Defourny S, De Meyer A, Desloovere A, Devlin Y, Diels M, Dokoupil K, Donald S, Evans S, Fasan I, Ferguson C, Ford S, Forga M, Gallo G, Grünert SC, Heddrich-Ellerbrok M, Heidenborg C, Jonkers C, Lefebure K, Luyten K, MacDonald A, Meyer U, Micciche A, Müller E, Portnoi P, Ripley S, Robert M, Robertson LV, Rosenbaum-Fabian S, Sahm K, Schultz S, Singleton K, Sjöqvist E, Stoelen L, Terry A, Thompson S, Timmer C, Vande Kerckhove K, van der Ploeg L, Van Driessche M, van Rijn M, van Teeffelen-Heithoff A, Vitoria I, Voillot C, Wenz J, Westbrook M, Wildgoose J, Zweers H.

Mol Genet Metab. 2015 May;115(1):23-6. doi: 10.1016/j.ymgme.2015.03.008. Epub 2015 Apr 7.

PMID:
25873073
29.

Systematic identification of signaling pathways with potential to confer anticancer drug resistance.

Martz CA, Ottina KA, Singleton KR, Jasper JS, Wardell SE, Peraza-Penton A, Anderson GR, Winter PS, Wang T, Alley HM, Kwong LN, Cooper ZA, Tetzlaff M, Chen PL, Rathmell JC, Flaherty KT, Wargo JA, McDonnell DP, Sabatini DM, Wood KC.

Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877.

30.

Long-Term Gestational Hypoxia Modulates Expression of Key Genes Governing Mitochondrial Function in the Perirenal Adipose of the Late Gestation Sheep Fetus.

Myers DA, Singleton K, Hyatt K, Mlynarczyk M, Kaushal KM, Ducsay CA.

Reprod Sci. 2015 Jun;22(6):654-63. doi: 10.1177/1933719114561554. Epub 2014 Dec 10.

31.

Transfer and transport: incorporating causal methods for improving predictive models.

Singleton KW, Bui AA, Hsu W.

J Am Med Inform Assoc. 2014 Oct;21(e2):e374-5. doi: 10.1136/amiajnl-2014-002968. Epub 2014 Jul 9. No abstract available.

32.

Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy.

Kim J, Vasu VT, Mishra R, Singleton KR, Yoo M, Leach SM, Farias-Hesson E, Mason RJ, Kang J, Ramamoorthy P, Kern JA, Heasley LE, Finigan JH, Tan AC.

Bioinformatics. 2014 Sep 1;30(17):2393-8. doi: 10.1093/bioinformatics/btu323. Epub 2014 May 7.

33.

Mutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes.

Larimore J, Zlatic SA, Gokhale A, Tornieri K, Singleton KS, Mullin AP, Tang J, Talbot K, Faundez V.

J Biol Chem. 2014 May 16;289(20):14291-300. doi: 10.1074/jbc.M114.553750. Epub 2014 Apr 8.

34.

Motivating the additional use of external validity: examining transportability in a model of glioblastoma multiforme.

Singleton KW, Speier W, Bui AA, Hsu W.

AMIA Annu Symp Proc. 2014 Nov 14;2014:1930-9. eCollection 2014.

35.

A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop.

Ware KE, Hinz TK, Kleczko E, Singleton KR, Marek LA, Helfrich BA, Cummings CT, Graham DK, Astling D, Tan AC, Heasley LE.

Oncogenesis. 2013 Mar 25;2:e39. doi: 10.1038/oncsis.2013.4.

36.
37.

Leptin receptor antagonist treatment ameliorates the effects of long-term maternal hypoxia on adrenal expression of key steroidogenic genes in the ovine fetus.

Ducsay CA, Furuta K, Vargas VE, Kaushal KM, Singleton K, Hyatt K, Myers DA.

Am J Physiol Regul Integr Comp Physiol. 2013 Mar 15;304(6):R435-42. doi: 10.1152/ajpregu.00377.2012. Epub 2013 Jan 23.

38.

Comparing predictive models of glioblastoma multiforme built using multi-institutional and local data sources.

Singleton KW, Hsu W, Bui AA.

AMIA Annu Symp Proc. 2012;2012:1385-92. Epub 2012 Nov 3.

39.

Distinct requirements for T-bet in gut innate lymphoid cells.

Sciumé G, Hirahara K, Takahashi H, Laurence A, Villarino AV, Singleton KL, Spencer SP, Wilhelm C, Poholek AC, Vahedi G, Kanno Y, Belkaid Y, O'Shea JJ.

J Exp Med. 2012 Dec 17;209(13):2331-8. doi: 10.1084/jem.20122097. Epub 2012 Dec 3.

40.

Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity.

Kanno Y, Vahedi G, Hirahara K, Singleton K, O'Shea JJ.

Annu Rev Immunol. 2012;30:707-31. doi: 10.1146/annurev-immunol-020711-075058. Epub 2012 Jan 6. Review.

41.

Wireless data collection of self-administered surveys using tablet computers.

Singleton KW, Lan M, Arnold C, Vahidi M, Arangua L, Gelberg L, Bui AA.

AMIA Annu Symp Proc. 2011;2011:1261-9. Epub 2011 Oct 22.

42.

Itk controls the spatiotemporal organization of T cell activation.

Singleton KL, Gosh M, Dandekar RD, Au-Yeung BB, Ksionda O, Tybulewicz VL, Altman A, Fowell DJ, Wülfing C.

Sci Signal. 2011 Oct 4;4(193):ra66. doi: 10.1126/scisignal.2001821.

43.

Fibroblast growth factor receptors are components of autocrine signaling networks in head and neck squamous cell carcinoma cells.

Marshall ME, Hinz TK, Kono SA, Singleton KR, Bichon B, Ware KE, Marek L, Frederick BA, Raben D, Heasley LE.

Clin Cancer Res. 2011 Aug 1;17(15):5016-25. doi: 10.1158/1078-0432.CCR-11-0050. Epub 2011 Jun 14.

44.

A word can be worth a thousand pictures.

Singleton KA.

Medsurg Nurs. 2010 Sep-Oct;19(5):262-3. No abstract available.

PMID:
21189736
45.

Understanding cultural and linguistic barriers to health literacy.

Singleton K, Krause EM.

Ky Nurse. 2010 Oct-Dec;58(4):4, 6-9.

PMID:
21053716
46.

No nursing shortage: being in the know.

Singleton KA.

Medsurg Nurs. 2010 Jul-Aug;19(4):209-10. No abstract available.

PMID:
20860245
47.

Dollars and sense.

Singleton KA.

Medsurg Nurs. 2009 Jul-Aug;18(4):211, 238. No abstract available.

PMID:
20552845
48.

Lasting impressions: Aunt Edna, Bessie, Judy, and Rosemary.

Singleton KA.

Medsurg Nurs. 2010 Mar-Apr;19(2):75, 83. No abstract available.

PMID:
20476514
49.

Lead, follow, and get in the way: the medical-surgical nurse's role in health care reform.

Singleton KA.

Medsurg Nurs. 2010 Jan-Feb;19(1):5-6. No abstract available.

PMID:
20336977
50.

Setting the record straight....

Singleton KA.

Medsurg Nurs. 2009 Sep-Oct;18(5):262, 308. No abstract available.

PMID:
19927959

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