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Items: 1 to 50 of 169

1.

Sinonasal adenoid cystic carcinoma-role of on-site FNAC: a case report.

Tummidi S, Kothari K, Patil R, Singhal SS, Shah V.

BMC Ear Nose Throat Disord. 2018 May 9;18:6. doi: 10.1186/s12901-018-0053-4. eCollection 2018.

2.

2'-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer.

Nagaprashantha LD, Singhal J, Li H, Warden C, Liu X, Horne D, Awasthi S, Salgia R, Singhal SS.

Oncotarget. 2018 Apr 6;9(26):18053-18068. doi: 10.18632/oncotarget.24720. eCollection 2018 Apr 6.

3.

Rlip depletion prevents spontaneous neoplasia in TP53 null mice.

Awasthi S, Tompkins J, Singhal J, Riggs AD, Yadav S, Wu X, Singh S, Warden C, Liu Z, Wang J, Slavin TP, Weitzel JN, Yuan YC, Awasthi M, Srivastava SK, Awasthi YC, Singhal SS.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3918-3923. doi: 10.1073/pnas.1719586115. Epub 2018 Mar 23.

4.

Solitary Intraspinal Juvenile Xanthogranuloma in an Infant.

Shenoy A, Singhal SS, Shinde S.

Asian J Neurosurg. 2018 Jan-Mar;13(1):172-175. doi: 10.4103/1793-5482.180896.

5.

Disseminated histoplasmosis in an immunocompetent patient - utility of skin scrape cytology in diagnosis: a case report.

Santosh T, Kothari K, Singhal SS, Shah VV, Patil R.

J Med Case Rep. 2018 Jan 12;12(1):7. doi: 10.1186/s13256-017-1543-5.

6.

Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment.

Chikara S, Nagaprashantha LD, Singhal J, Horne D, Awasthi S, Singhal SS.

Cancer Lett. 2018 Jan 28;413:122-134. doi: 10.1016/j.canlet.2017.11.002. Epub 2017 Nov 4. Review.

PMID:
29113871
7.

2'-Hydroxyflavanone: A novel strategy for targeting breast cancer.

Singhal J, Nagaprashantha L, Chikara S, Awasthi S, Horne D, Singhal SS.

Oncotarget. 2017 Aug 24;8(43):75025-75037. doi: 10.18632/oncotarget.20499. eCollection 2017 Sep 26.

8.

Translational opportunities for broad-spectrum natural phytochemicals and targeted agent combinations in breast cancer.

Dalasanur Nagaprashantha L, Adhikari R, Singhal J, Chikara S, Awasthi S, Horne D, Singhal SS.

Int J Cancer. 2018 Feb 15;142(4):658-670. doi: 10.1002/ijc.31085. Epub 2017 Nov 28. Review.

PMID:
28975625
9.

Incidental detection of two adult gravid filarial worms in breast: a case report.

Tummidi S, Kothari K, Patil R, Singhal SS, Keshan P.

BMC Res Notes. 2017 Aug 16;10(1):412. doi: 10.1186/s13104-017-2709-3.

10.

RLIP76 Inhibition: A Promising Developmental Therapy for Neuroblastoma.

Singhal SS, Nagaprashantha L, Singhal P, Singhal S, Singhal J, Awasthi S, Horne D.

Pharm Res. 2017 Aug;34(8):1673-1682. doi: 10.1007/s11095-017-2154-y. Epub 2017 Apr 6. Review.

PMID:
28386633
11.

Targeting the mercapturic acid pathway and vicenin-2 for prevention of prostate cancer.

Singhal SS, Jain D, Singhal P, Awasthi S, Singhal J, Horne D.

Biochim Biophys Acta. 2017 Aug;1868(1):167-175. doi: 10.1016/j.bbcan.2017.03.009. Epub 2017 Mar 28. Review.

PMID:
28359741
12.

Lipid Peroxidation Products in Human Health and Disease 2016.

Ramana KV, Srivastava S, Singhal SS.

Oxid Med Cell Longev. 2017;2017:2163285. doi: 10.1155/2017/2163285. Epub 2017 Feb 28. No abstract available.

13.

Didymin: an orally active citrus flavonoid for targeting neuroblastoma.

Singhal SS, Singhal S, Singhal P, Singhal J, Horne D, Awasthi S.

Oncotarget. 2017 Apr 25;8(17):29428-29441. doi: 10.18632/oncotarget.15204. Review.

14.

SR4 Uncouples Mitochondrial Oxidative Phosphorylation, Modulates AMP-dependent Kinase (AMPK)-Mammalian Target of Rapamycin (mTOR) Signaling, and Inhibits Proliferation of HepG2 Hepatocarcinoma Cells.

Figarola JL, Singhal J, Tompkins JD, Rogers GW, Warden C, Horne D, Riggs AD, Awasthi S, Singhal SS.

J Biol Chem. 2015 Dec 18;290(51):30321-41. doi: 10.1074/jbc.M115.686352. Epub 2015 Nov 3.

15.

RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes.

Wurtzel JG, Lee S, Singhal SS, Awasthi S, Ginsberg MH, Goldfinger LE.

Biochem Biophys Res Commun. 2015 Nov 27;467(4):785-91. doi: 10.1016/j.bbrc.2015.10.064. Epub 2015 Oct 20.

16.

Antioxidant role of glutathione S-transferases: 4-Hydroxynonenal, a key molecule in stress-mediated signaling.

Singhal SS, Singh SP, Singhal P, Horne D, Singhal J, Awasthi S.

Toxicol Appl Pharmacol. 2015 Dec 15;289(3):361-70. doi: 10.1016/j.taap.2015.10.006. Epub 2015 Oct 23. Review.

17.

RLIP76 Targeted Therapy for Kidney Cancer.

Singhal SS, Singhal J, Figarola J, Horne D, Awasthi S.

Pharm Res. 2015 Oct;32(10):3123-36. doi: 10.1007/s11095-015-1723-1. Epub 2015 May 29. Review.

18.

2'-Hydroxyflavanone: A promising molecule for kidney cancer prevention.

Singhal SS, Singhal J, Figarola JL, Riggs A, Horne D, Awasthi S.

Biochem Pharmacol. 2015 Aug 1;96(3):151-8. doi: 10.1016/j.bcp.2015.04.022. Epub 2015 May 6. Review.

PMID:
25957660
19.

Therapeutic potential of natural pharmacological agents in the treatment of human diseases.

Ramana KV, Singhal SS, Reddy AB.

Biomed Res Int. 2014;2014:573452. doi: 10.1155/2014/573452. Epub 2014 Dec 28. No abstract available.

20.

Lipid peroxidation products in human health and disease 2014.

Ramana KV, Srivastava S, Singhal SS.

Oxid Med Cell Longev. 2014;2014:162414. doi: 10.1155/2014/162414. Epub 2014 Sep 14. No abstract available.

21.

LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells.

Figarola JL, Singhal J, Rahbar S, Awasthi S, Singhal SS.

Apoptosis. 2014 May;19(5):776-88. doi: 10.1007/s10495-014-0974-3.

22.

COH-SR4 reduces body weight, improves glycemic control and prevents hepatic steatosis in high fat diet-induced obese mice.

Figarola JL, Singhal P, Rahbar S, Gugiu BG, Awasthi S, Singhal SS.

PLoS One. 2013 Dec 20;8(12):e83801. doi: 10.1371/journal.pone.0083801. eCollection 2013.

23.

Lipid peroxidation products in human health and disease.

Ramana KV, Srivastava S, Singhal SS.

Oxid Med Cell Longev. 2013;2013:583438. doi: 10.1155/2013/583438. Epub 2013 Nov 2. No abstract available.

24.

Novel compound 1,3-bis (3,5-dichlorophenyl) urea inhibits lung cancer progression.

Singhal SS, Figarola J, Singhal J, Nagaprashantha L, Berz D, Rahbar S, Awasthi S.

Biochem Pharmacol. 2013 Dec 15;86(12):1664-72. doi: 10.1016/j.bcp.2013.09.022. Epub 2013 Oct 4.

25.

Proteomic analysis of signaling network regulation in renal cell carcinomas with differential hypoxia-inducible factor-2α expression.

Nagaprashantha LD, Talamantes T, Singhal J, Guo J, Vatsyayan R, Rauniyar N, Awasthi S, Singhal SS, Prokai L.

PLoS One. 2013 Aug 5;8(8):e71654. doi: 10.1371/journal.pone.0071654. Print 2013.

26.

RLIP76 protein knockdown attenuates obesity due to a high-fat diet.

Singhal SS, Figarola J, Singhal J, Reddy MA, Liu X, Berz D, Natarajan R, Awasthi S.

J Biol Chem. 2013 Aug 9;288(32):23394-406. doi: 10.1074/jbc.M113.480194. Epub 2013 Jul 2.

27.

Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

Yadav A, Janaratne T, Krishnan A, Singhal SS, Yadav S, Dayoub AS, Hawkins DL, Awasthi S, MacDonnell FM.

Mol Cancer Ther. 2013 May;12(5):643-53. doi: 10.1158/1535-7163.MCT-12-1130. Epub 2013 Feb 26.

28.

1,3-Bis(3,5-dichlorophenyl) urea compound 'COH-SR4' inhibits proliferation and activates apoptosis in melanoma.

Singhal SS, Figarola J, Singhal J, Leake K, Nagaprashantha L, Lincoln C, Gabriel Gugiu B, Horne D, Jove R, Awasthi S, Rahbar S.

Biochem Pharmacol. 2012 Dec 1;84(11):1419-27. doi: 10.1016/j.bcp.2012.08.020. Epub 2012 Aug 28.

29.

RALBP1/RLIP76 depletion in mice suppresses tumor growth by inhibiting tumor neovascularization.

Lee S, Wurtzel JG, Singhal SS, Awasthi S, Goldfinger LE.

Cancer Res. 2012 Oct 15;72(20):5165-73. doi: 10.1158/0008-5472.CAN-12-0468. Epub 2012 Aug 17.

30.

RLIP76 regulates PI3K/Akt signaling and chemo-radiotherapy resistance in pancreatic cancer.

Leake K, Singhal J, Nagaprashantha LD, Awasthi S, Singhal SS.

PLoS One. 2012;7(4):e34582. doi: 10.1371/journal.pone.0034582. Epub 2012 Apr 3.

31.

Novel anti-cancer compounds for developing combinatorial therapies to target anoikis-resistant tumors.

Nagaprashantha L, Vartak N, Awasthi S, Awasthi S, Singhal SS.

Pharm Res. 2012 Mar;29(3):621-36. doi: 10.1007/s11095-011-0645-9. Epub 2011 Dec 28. Review.

PMID:
22203324
32.

Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma.

Singhal J, Nagaprashantha LD, Vatsyayan R, Ashutosh, Awasthi S, Singhal SS.

Cancer Prev Res (Phila). 2012 Mar;5(3):473-83. doi: 10.1158/1940-6207.CAPR-11-0318. Epub 2011 Dec 15.

33.

Nutlin-3 enhances sorafenib efficacy in renal cell carcinoma.

Vatsyayan R, Singhal J, Nagaprashantha LD, Awasthi S, Singhal SS.

Mol Carcinog. 2013 Jan;52(1):39-48. doi: 10.1002/mc.20875. Epub 2011 Oct 17.

34.

RLIP76, a glutathione-conjugate transporter, plays a major role in the pathogenesis of metabolic syndrome.

Singhal J, Nagaprashantha L, Vatsyayan R, Awasthi S, Singhal SS.

PLoS One. 2011;6(9):e24688. doi: 10.1371/journal.pone.0024688. Epub 2011 Sep 13.

35.

Endotracheal intubation skill acquisition by medical students.

Tarasi PG, Mangione MP, Singhal SS, Wang HE.

Med Educ Online. 2011;16. doi: 10.3402/meo.v16i0.7309. Epub 2011 Aug 23.

36.

Anti-cancer effects of novel flavonoid vicenin-2 as a single agent and in synergistic combination with docetaxel in prostate cancer.

Nagaprashantha LD, Vatsyayan R, Singhal J, Fast S, Roby R, Awasthi S, Singhal SS.

Biochem Pharmacol. 2011 Nov 1;82(9):1100-9. doi: 10.1016/j.bcp.2011.07.078. Epub 2011 Jul 23.

37.

Targeting p53-null neuroblastomas through RLIP76.

Singhal J, Yadav S, Nagaprashantha LD, Vatsyayan R, Singhal SS, Awasthi S.

Cancer Prev Res (Phila). 2011 Jun;4(6):879-89. doi: 10.1158/1940-6207.CAPR-11-0025. Epub 2011 Mar 16.

38.

2'-hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma.

Nagaprashantha LD, Vatsyayan R, Singhal J, Lelsani P, Prokai L, Awasthi S, Singhal SS.

Carcinogenesis. 2011 Apr;32(4):568-75. doi: 10.1093/carcin/bgr021. Epub 2011 Feb 8.

39.

Glutathione-conjugate transport by RLIP76 is required for clathrin-dependent endocytosis and chemical carcinogenesis.

Singhal SS, Wickramarachchi D, Yadav S, Singhal J, Leake K, Vatsyayan R, Chaudhary P, Lelsani P, Suzuki S, Yang S, Awasthi YC, Awasthi S.

Mol Cancer Ther. 2011 Jan;10(1):16-28. doi: 10.1158/1535-7163.MCT-10-0699.

40.

The sensors and regulators of cell-matrix surveillance in anoikis resistance of tumors.

Nagaprashantha LD, Vatsyayan R, Lelsani PC, Awasthi S, Singhal SS.

Int J Cancer. 2011 Feb 15;128(4):743-52. doi: 10.1002/ijc.25725. Epub 2010 Dec 7. Review.

41.

Mechanisms of 4-hydroxy-2-nonenal induced pro- and anti-apoptotic signaling.

Chaudhary P, Sharma R, Sharma A, Vatsyayan R, Yadav S, Singhal SS, Rauniyar N, Prokai L, Awasthi S, Awasthi YC.

Biochemistry. 2010 Jul 27;49(29):6263-75. doi: 10.1021/bi100517x.

42.

RLIP76: a versatile transporter and an emerging target for cancer therapy.

Vatsyayan R, Lelsani PC, Awasthi S, Singhal SS.

Biochem Pharmacol. 2010 Jun 15;79(12):1699-705. doi: 10.1016/j.bcp.2010.01.016. Epub 2010 Jan 25. Review.

43.

A central role of RLIP76 in regulation of glycemic control.

Awasthi S, Singhal SS, Yadav S, Singhal J, Vatsyayan R, Zajac E, Luchowski R, Borvak J, Gryczynski K, Awasthi YC.

Diabetes. 2010 Mar;59(3):714-25. doi: 10.2337/db09-0911. Epub 2009 Dec 10.

44.

Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer.

Singhal SS, Sehrawat A, Sahu M, Singhal P, Vatsyayan R, Rao Lelsani PC, Yadav S, Awasthi S.

Int J Cancer. 2010 Mar 15;126(6):1327-38. doi: 10.1002/ijc.24767.

45.

hSET1: a novel approach for colon cancer therapy.

Yadav S, Singhal J, Singhal SS, Awasthi S.

Biochem Pharmacol. 2009 May 15;77(10):1635-41. doi: 10.1016/j.bcp.2009.02.019. Epub 2009 Mar 6.

46.

Role of RLIP76 in doxorubicin resistance in lung cancer.

Vatsyayan R, Chaudhary P, Lelsani PC, Singhal P, Awasthi YC, Awasthi S, Singhal SS.

Int J Oncol. 2009 Jun;34(6):1505-11. Review.

47.

RLIP76: a target for kidney cancer therapy.

Singhal SS, Singhal J, Yadav S, Sahu M, Awasthi YC, Awasthi S.

Cancer Res. 2009 May 15;69(10):4244-51. doi: 10.1158/0008-5472.CAN-08-3521. Epub 2009 May 5. Erratum in: Cancer Res. 2009 Nov 15;69(22):8832.

48.

Increased expression of cdc2 inhibits transport function of RLIP76 and promotes apoptosis.

Singhal SS, Yadav S, Vatsyayan R, Chaudhary P, Borvak J, Singhal J, Awasthi S.

Cancer Lett. 2009 Oct 8;283(2):152-8. doi: 10.1016/j.canlet.2009.03.033. Epub 2009 Apr 17.

49.

Functional reconstitution of RLIP76 catalyzing ATP-dependent transport of glutathione-conjugates.

Singhal SS, Sehrawat A, Mehta A, Sahu M, Awasthi S.

Int J Oncol. 2009 Jan;34(1):191-9.

50.

Regression of prostate cancer xenografts by RLIP76 depletion.

Singhal SS, Roth C, Leake K, Singhal J, Yadav S, Awasthi S.

Biochem Pharmacol. 2009 Mar 15;77(6):1074-83. doi: 10.1016/j.bcp.2008.11.013. Epub 2008 Nov 25.

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