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Sleep duration over 28 years, cognition, gray matter volume, and white matter microstructure: a prospective cohort study.

Zitser J, Anatürk M, Zsoldos E, Mahmood A, Filippini N, Suri S, Leng Y, Yaffe K, Singh-Manoux A, Kivimaki M, Ebmeier K, Sexton C.

Sleep. 2020 Jan 6. pii: zsz290. doi: 10.1093/sleep/zsz290. [Epub ahead of print]


Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta-analysis consisting 2.8 million adults with 57 294 cases of dementia.

Lee CM, Woodward M, Batty GD, Beiser AS, Bell S, Berr C, Bjertness E, Chalmers J, Clarke R, Dartigues JF, Davis-Plourde K, Debette S, Di Angelantonio E, Feart C, Frikke-Schmidt R, Gregson J, Haan MN, Hassing LB, Hayden KM, Hoevenaar-Blom MP, Kaprio J, Kivimaki M, Lappas G, Larson EB, LeBlanc ES, Lee A, Lui LY, Moll van Charante EP, Ninomiya T, Nordestgaard LT, Ohara T, Ohkuma T, Palviainen T, Peres K, Peters R, Qizilbash N, Richard E, Rosengren A, Seshadri S, Shipley M, Singh-Manoux A, Strand BH, van Gool WA, Vuoksimaa E, Yaffe K, Huxley RR.

Obes Rev. 2020 Jan 3. doi: 10.1111/obr.12989. [Epub ahead of print] Review.


Social inequalities in multimorbidity, frailty, disability, and transitions to mortality: a 24-year follow-up of the Whitehall II cohort study.

Dugravot A, Fayosse A, Dumurgier J, Bouillon K, Rayana TB, Schnitzler A, Kivimaki M, Sabia S, Singh-Manoux A.

Lancet Public Health. 2020 Jan;5(1):e42-e50. doi: 10.1016/S2468-2667(19)30226-9. Epub 2019 Dec 16.


Longitudinal associations between diurnal cortisol variation and later-life cognitive impairment.

Tsui A, Richards M, Singh-Manoux A, Udeh-Momoh C, Davis D.

Neurology. 2020 Jan 14;94(2):e133-e141. doi: 10.1212/WNL.0000000000008729. Epub 2019 Dec 12.


Association of moderate and vigorous physical activity with incidence of type 2 diabetes and subsequent mortality: 27 year follow-up of the Whitehall II study.

Yerramalla MS, Fayosse A, Dugravot A, Tabak AG, Kivimäki M, Singh-Manoux A, Sabia S.

Diabetologia. 2019 Dec 2. doi: 10.1007/s00125-019-05050-1. [Epub ahead of print]


Association of aortic stiffness with cognitive decline: Whitehall II longitudinal cohort study.

Araghi M, Shipley MJ, Wilkinson IB, McEniery CM, Valencia-Hernández CA, Kivimaki M, Sabia S, Singh-Manoux A, Brunner EJ.

Eur J Epidemiol. 2019 Nov 27. doi: 10.1007/s10654-019-00586-3. [Epub ahead of print]


Long working hours and change in body weight: analysis of individual-participant data from 19 cohort studies.

Virtanen M, Jokela M, Lallukka T, Magnusson Hanson L, Pentti J, Nyberg ST, Alfredsson L, Batty GD, Casini A, Clays E, DeBacquer D, Ervasti J, Fransson E, Halonen JI, Head J, Kittel F, Knutsson A, Leineweber C, Nordin M, Oksanen T, Pietiläinen O, Rahkonen O, Salo P, Singh-Manoux A, Stenholm S, Suominen SB, Theorell T, Vahtera J, Westerholm P, Westerlund H, Kivimäki M.

Int J Obes (Lond). 2019 Nov 25. doi: 10.1038/s41366-019-0480-3. [Epub ahead of print]


Relation between 20-year income volatility and brain health in midlife: The CARDIA study.

Grasset L, Glymour MM, Elfassy T, Swift SL, Yaffe K, Singh-Manoux A, Zeki Al Hazzouri A.

Neurology. 2019 Nov 12;93(20):e1890-e1899. doi: 10.1212/WNL.0000000000008463. Epub 2019 Oct 2.


Long-term exposure to greenspace and metabolic syndrome: A Whitehall II study.

de Keijzer C, Basagaña X, Tonne C, Valentín A, Alonso J, Antó JM, Nieuwenhuijsen MJ, Kivimäki M, Singh-Manoux A, Sunyer J, Dadvand P.

Environ Pollut. 2019 Dec;255(Pt 2):113231. doi: 10.1016/j.envpol.2019.113231. Epub 2019 Sep 13.


Change in Cardiovascular Health and Incident Type 2 Diabetes and Impaired Fasting Glucose: The Whitehall II Study.

Climie RE, van Sloten TT, Périer MC, Tafflet M, Fayosse A, Dugravot A, Singh-Manoux A, Empana JP.

Diabetes Care. 2019 Oct;42(10):1981-1987. doi: 10.2337/dc19-0379. Epub 2019 Aug 15.


Epidemiological transition in morbidity: 10-year data from emergency consultations in Dakar, Senegal.

Gaye B, Diop M, Narayanan K, Offredo L, Reese P, Antignac M, Diop V, Mbacké AB, Boyer Chatenet L, Marijon E, Singh-Manoux A, Diop IB, Jouven X.

BMJ Glob Health. 2019 Jul 19;4(4):e001396. doi: 10.1136/bmjgh-2019-001396. eCollection 2019.


Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study.

Sabia S, Fayosse A, Dumurgier J, Schnitzler A, Empana JP, Ebmeier KP, Dugravot A, Kivimäki M, Singh-Manoux A.

BMJ. 2019 Aug 7;366:l4414. doi: 10.1136/bmj.l4414.


Association between major surgical admissions and the cognitive trajectory: 19 year follow-up of Whitehall II cohort study.

Krause BM, Sabia S, Manning HJ, Singh-Manoux A, Sanders RD.

BMJ. 2019 Aug 7;366:l4466. doi: 10.1136/bmj.l4466.


Does Poorer Pulmonary Function Accelerate Arterial Stiffening?: A Cohort Study With Repeated Measurements of Carotid-Femoral Pulse Wave Velocity.

Okamoto M, Shipley MJ, Wilkinson IB, McEniery CM, Valencia-Hernández CA, Singh-Manoux A, Kivimaki M, Brunner EJ.

Hypertension. 2019 Oct;74(4):929-935. doi: 10.1161/HYPERTENSIONAHA.119.13183. Epub 2019 Aug 5.


Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study.

Sommerlad A, Sabia S, Singh-Manoux A, Lewis G, Livingston G.

PLoS Med. 2019 Aug 2;16(8):e1002862. doi: 10.1371/journal.pmed.1002862. eCollection 2019 Aug.


The association between accelerometer-assessed physical activity and respiratory function in older adults differs between smokers and non-smokers.

Benadjaoud MA, Menai M, van Hees VT, Zipunnikov V, Regnaux JP, Kivimäki M, Singh-Manoux A, Sabia S.

Sci Rep. 2019 Jul 16;9(1):10270. doi: 10.1038/s41598-019-46771-y.


Association of Midlife Cardiovascular Risk Profiles With Cerebral Perfusion at Older Ages.

Suri S, Topiwala A, Chappell MA, Okell TW, Zsoldos E, Singh-Manoux A, Kivimäki M, Mackay CE, Ebmeier KP.

JAMA Netw Open. 2019 Jun 5;2(6):e195776. doi: 10.1001/jamanetworkopen.2019.5776.


Biomarker profiles of Alzheimer's disease and dynamic of the association between cerebrospinal fluid levels of β-amyloid peptide and tau.

Lafirdeen ASM, Cognat E, Sabia S, Hourregue C, Lilamand M, Dugravot A, Bouaziz-Amar E, Laplanche JL, Hugon J, Singh-Manoux A, Paquet C, Dumurgier J.

PLoS One. 2019 May 14;14(5):e0217026. doi: 10.1371/journal.pone.0217026. eCollection 2019.


Physical inactivity, cardiometabolic disease, and risk of dementia: an individual-participant meta-analysis.

Kivimäki M, Singh-Manoux A, Pentti J, Sabia S, Nyberg ST, Alfredsson L, Goldberg M, Knutsson A, Koskenvuo M, Koskinen A, Kouvonen A, Nordin M, Oksanen T, Strandberg T, Suominen SB, Theorell T, Vahtera J, Väänänen A, Virtanen M, Westerholm P, Westerlund H, Zins M, Seshadri S, Batty GD, Sipilä PN, Shipley MJ, Lindbohm JV, Ferrie JE, Jokela M; IPD-Work consortium.

BMJ. 2019 Apr 17;365:l1495. doi: 10.1136/bmj.l1495.


Carotid artery wave intensity in mid- to late-life predicts cognitive decline: the Whitehall II study.

Chiesa ST, Masi S, Shipley MJ, Ellins EA, Fraser AG, Hughes AD, Patel RS, Khir AW, Halcox JP, Singh-Manoux A, Kivimaki M, Celermajer DS, Deanfield JE.

Eur Heart J. 2019 Jul 21;40(28):2300-2309. doi: 10.1093/eurheartj/ehz189.


5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study.

Lindbohm JV, Sipilä PN, Mars NJ, Pentti J, Ahmadi-Abhari S, Brunner EJ, Shipley MJ, Singh-Manoux A, Tabak AG, Kivimäki M.

Lancet Public Health. 2019 Apr;4(4):e189-e199. doi: 10.1016/S2468-2667(19)30023-4.


CSF level of β-amyloid peptide predicts mortality in Alzheimer's disease.

Boumenir A, Cognat E, Sabia S, Hourregue C, Lilamand M, Dugravot A, Bouaziz-Amar E, Laplanche JL, Hugon J, Singh-Manoux A, Paquet C, Dumurgier J.

Alzheimers Res Ther. 2019 Mar 28;11(1):29. doi: 10.1186/s13195-019-0481-4.


Association of Midlife Diet With Subsequent Risk for Dementia.

Akbaraly TN, Singh-Manoux A, Dugravot A, Brunner EJ, Kivimäki M, Sabia S.

JAMA. 2019 Mar 12;321(10):957-968. doi: 10.1001/jama.2019.1432.


Predicting cognitive resilience from midlife lifestyle and multi-modal MRI: A 30-year prospective cohort study.

Topiwala A, Suri S, Allan C, Valkanova V, Filippini N, Sexton CE, Heise V, Zsoldos E, Mahmood A, Singh-Manoux A, Mackay CE, Kivimäki M, Ebmeier KP.

PLoS One. 2019 Feb 19;14(2):e0211273. doi: 10.1371/journal.pone.0211273. eCollection 2019.


Raised blood pressure and risk of dementia: our response.

Abell JG, Sabia S, Singh-Manoux A.

Eur Heart J. 2019 Mar 1;40(9):787. doi: 10.1093/eurheartj/ehy917. No abstract available.


Hospitalisation of people with dementia: evidence from English electronic health records from 2008 to 2016.

Sommerlad A, Perera G, Mueller C, Singh-Manoux A, Lewis G, Stewart R, Livingston G.

Eur J Epidemiol. 2019 Jun;34(6):567-577. doi: 10.1007/s10654-019-00481-x. Epub 2019 Jan 16.


Association between gait and cognition in an elderly population based sample.

Valkanova V, Esser P, Demnitz N, Sexton CE, Zsoldos E, Mahmood A, Griffanti L, Kivimäki M, Singh-Manoux A, Dawes H, Ebmeier KP.

Gait Posture. 2018 Sep;65:240-245. doi: 10.1016/j.gaitpost.2018.07.178. Epub 2018 Jul 29.


Green and blue spaces and physical functioning in older adults: Longitudinal analyses of the Whitehall II study.

de Keijzer C, Tonne C, Sabia S, Basagaña X, Valentín A, Singh-Manoux A, Antó JM, Alonso J, Nieuwenhuijsen MJ, Sunyer J, Dadvand P.

Environ Int. 2019 Jan;122:346-356. doi: 10.1016/j.envint.2018.11.046. Epub 2018 Nov 29.


Re: Accuracy of general hospital dementia diagnoses in England: Sensitivity, specificity, and predictors of diagnostic accuracy 2008-2016.

Sommerlad A, Perera G, Singh-Manoux A, Lewis G, Stewart R, Livingston G.

Alzheimers Dement. 2019 Feb;15(2):313-314. doi: 10.1016/j.jalz.2018.11.001. Epub 2018 Dec 21. No abstract available.


Association of Change in Cardiovascular Risk Factors With Incident Cardiovascular Events.

van Sloten TT, Tafflet M, Périer MC, Dugravot A, Climie RED, Singh-Manoux A, Empana JP.

JAMA. 2018 Nov 6;320(17):1793-1804. doi: 10.1001/jama.2018.16975.


Reader response: Midlife cardiovascular fitness and dementia: A 44-year longitudinal population study in women.

Kivimäki M, Pentti J, Singh-Manoux A.

Neurology. 2018 Oct 16;91(16):762-763. doi: 10.1212/WNL.0000000000006348. No abstract available.


Obesity and loss of disease-free years owing to major non-communicable diseases: a multicohort study.

Nyberg ST, Batty GD, Pentti J, Virtanen M, Alfredsson L, Fransson EI, Goldberg M, Heikkilä K, Jokela M, Knutsson A, Koskenvuo M, Lallukka T, Leineweber C, Lindbohm JV, Madsen IEH, Magnusson Hanson LL, Nordin M, Oksanen T, Pietiläinen O, Rahkonen O, Rugulies R, Shipley MJ, Stenholm S, Suominen S, Theorell T, Vahtera J, Westerholm PJM, Westerlund H, Zins M, Hamer M, Singh-Manoux A, Bell JA, Ferrie JE, Kivimäki M.

Lancet Public Health. 2018 Oct;3(10):e490-e497. doi: 10.1016/S2468-2667(18)30139-7. Epub 2018 Sep 1.


Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study.

Sabia S, Fayosse A, Dumurgier J, Dugravot A, Akbaraly T, Britton A, Kivimäki M, Singh-Manoux A.

BMJ. 2018 Aug 1;362:k2927. doi: 10.1136/bmj.k2927.


Residential Surrounding Greenness and Cognitive Decline: A 10-Year Follow-up of the Whitehall II Cohort.

de Keijzer C, Tonne C, Basagaña X, Valentín A, Singh-Manoux A, Alonso J, Antó JM, Nieuwenhuijsen MJ, Sunyer J, Dadvand P.

Environ Health Perspect. 2018 Jul 12;126(7):077003. doi: 10.1289/EHP2875. eCollection 2018 Jul.


Unfavorable and favorable changes in modifiable risk factors and incidence of coronary heart disease: The Whitehall II cohort study.

Virtanen M, Vahtera J, Singh-Manoux A, Elovainio M, Ferrie JE, Kivimäki M.

Int J Cardiol. 2018 Oct 15;269:7-12. doi: 10.1016/j.ijcard.2018.07.005. Epub 2018 Jul 5.


Midlife contributors to socioeconomic differences in frailty during later life: a prospective cohort study.

Brunner EJ, Shipley MJ, Ahmadi-Abhari S, Valencia Hernandez C, Abell JG, Singh-Manoux A, Kawachi I, Kivimaki M.

Lancet Public Health. 2018 Jul;3(7):e313-e322. doi: 10.1016/S2468-2667(18)30079-3. Epub 2018 Jun 14.


Association between systolic blood pressure and dementia in the Whitehall II cohort study: role of age, duration, and threshold used to define hypertension.

Abell JG, Kivimäki M, Dugravot A, Tabak AG, Fayosse A, Shipley M, Sabia S, Singh-Manoux A.

Eur Heart J. 2018 Sep 1;39(33):3119-3125. doi: 10.1093/eurheartj/ehy288.


Work stress and risk of death in men and women with and without cardiometabolic disease: a multicohort study.

Kivimäki M, Pentti J, Ferrie JE, Batty GD, Nyberg ST, Jokela M, Virtanen M, Alfredsson L, Dragano N, Fransson EI, Goldberg M, Knutsson A, Koskenvuo M, Koskinen A, Kouvonen A, Luukkonen R, Oksanen T, Rugulies R, Siegrist J, Singh-Manoux A, Suominen S, Theorell T, Väänänen A, Vahtera J, Westerholm PJM, Westerlund H, Zins M, Strandberg T, Steptoe A, Deanfield J; IPD-Work consortium.

Lancet Diabetes Endocrinol. 2018 Sep;6(9):705-713. doi: 10.1016/S2213-8587(18)30140-2. Epub 2018 Jun 5.


Association of circulating metabolites with healthy diet and risk of cardiovascular disease: analysis of two cohort studies.

Akbaraly T, Würtz P, Singh-Manoux A, Shipley MJ, Haapakoski R, Lehto M, Desrumaux C, Kähönen M, Lehtimäki T, Mikkilä V, Hingorani A, Humphries SE, Kangas AJ, Soininen P, Raitakari O, Ala-Korpela M, Kivimäki M.

Sci Rep. 2018 Jun 5;8(1):8620. doi: 10.1038/s41598-018-26441-1.


Clinical, socioeconomic, and behavioural factors at age 50 years and risk of cardiometabolic multimorbidity and mortality: A cohort study.

Singh-Manoux A, Fayosse A, Sabia S, Tabak A, Shipley M, Dugravot A, Kivimäki M.

PLoS Med. 2018 May 21;15(5):e1002571. doi: 10.1371/journal.pmed.1002571. eCollection 2018 May.


Accuracy of general hospital dementia diagnoses in England: Sensitivity, specificity, and predictors of diagnostic accuracy 2008-2016.

Sommerlad A, Perera G, Singh-Manoux A, Lewis G, Stewart R, Livingston G.

Alzheimers Dement. 2018 Jul;14(7):933-943. doi: 10.1016/j.jalz.2018.02.012. Epub 2018 Apr 25.


Prevention of dementia by targeting risk factors.

Kivimäki M, Singh-Manoux A.

Lancet. 2018 Apr 21;391(10130):1574-1575. doi: 10.1016/S0140-6736(18)30578-6. No abstract available.


Allostatic load as a predictor of grey matter volume and white matter integrity in old age: The Whitehall II MRI study.

Zsoldos E, Filippini N, Mahmood A, Mackay CE, Singh-Manoux A, Kivimäki M, Jenkinson M, Ebmeier KP.

Sci Rep. 2018 Apr 23;8(1):6411. doi: 10.1038/s41598-018-24398-9.


Testosterone and All-Cause Mortality in Older Men: The Role of Metabolic Syndrome.

Laouali N, Brailly-Tabard S, Helmer C, Ancelin ML, Tzourio C, Singh-Manoux A, Dugravot A, Elbaz A, Guiochon-Mantel A, Canonico M.

J Endocr Soc. 2018 Feb 26;2(4):322-335. doi: 10.1210/js.2018-00005. eCollection 2018 Apr 1.


Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts.

Tynkkynen J, Chouraki V, van der Lee SJ, Hernesniemi J, Yang Q, Li S, Beiser A, Larson MG, Sääksjärvi K, Shipley MJ, Singh-Manoux A, Gerszten RE, Wang TJ, Havulinna AS, Würtz P, Fischer K, Demirkan A, Ikram MA, Amin N, Lehtimäki T, Kähönen M, Perola M, Metspalu A, Kangas AJ, Soininen P, Ala-Korpela M, Vasan RS, Kivimäki M, van Duijn CM, Seshadri S, Salomaa V.

Alzheimers Dement. 2018 Jun;14(6):723-733. doi: 10.1016/j.jalz.2018.01.003. Epub 2018 Mar 6.


Exploring variability in basal ganglia connectivity with functional MRI in healthy aging.

Griffanti L, Stratmann P, Rolinski M, Filippini N, Zsoldos E, Mahmood A, Zamboni G, Douaud G, Klein JC, Kivimäki M, Singh-Manoux A, Hu MT, Ebmeier KP, Mackay CE.

Brain Imaging Behav. 2018 Dec;12(6):1822-1827. doi: 10.1007/s11682-018-9824-1.


Socioeconomic inequality in recovery from poor physical and mental health in mid-life and early old age: prospective Whitehall II cohort study.

Tanaka A, Shipley MJ, Welch CA, Groce NE, Marmot MG, Kivimaki M, Singh-Manoux A, Brunner EJ.

J Epidemiol Community Health. 2018 Apr;72(4):309-313. doi: 10.1136/jech-2017-209584. Epub 2018 Feb 8.


Cardiometabolic dysregulation and cognitive decline: potential role of depressive symptoms.

Schmitz N, Deschênes SS, Burns RJ, Danna SM, Franco OH, Ikram MA, Kivimäki M, Singh-Manoux A, Tiemeier H.

Br J Psychiatry. 2018 Feb;212(2):96-102. doi: 10.1192/bjp.2017.26.


Long working hours and depressive symptoms: systematic review and meta-analysis of published studies and unpublished individual participant data.

Virtanen M, Jokela M, Madsen IE, Magnusson Hanson LL, Lallukka T, Nyberg ST, Alfredsson L, Batty GD, Bjorner JB, Borritz M, Burr H, Dragano N, Erbel R, Ferrie JE, Heikkilä K, Knutsson A, Koskenvuo M, Lahelma E, Nielsen ML, Oksanen T, Pejtersen JH, Pentti J, Rahkonen O, Rugulies R, Salo P, Schupp J, Shipley MJ, Siegrist J, Singh-Manoux A, Suominen SB, Theorell T, Vahtera J, Wagner GG, Wang JL, Yiengprugsawan V, Westerlund H, Kivimäki M.

Scand J Work Environ Health. 2018 May 1;44(3):239-250. doi: 10.5271/sjweh.3712. Epub 2018 Feb 8.


Transitions across cognitive states and death among older adults in relation to education: A multistate survival model using data from six longitudinal studies.

Robitaille A, van den Hout A, Machado RJM, Bennett DA, Čukić I, Deary IJ, Hofer SM, Hoogendijk EO, Huisman M, Johansson B, Koval AV, van der Noordt M, Piccinin AM, Rijnhart JJM, Singh-Manoux A, Skoog J, Skoog I, Starr J, Vermunt L, Clouston S, Muniz Terrera G.

Alzheimers Dement. 2018 Apr;14(4):462-472. doi: 10.1016/j.jalz.2017.10.003. Epub 2018 Feb 1.

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