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Items: 1 to 50 of 257

1.

How RNA structure dictates the usage of a critical exon of spinal muscular atrophy gene.

Singh NN, Singh RN.

Biochim Biophys Acta Gene Regul Mech. 2019 Jul 16. pii: S1874-9399(18)30510-8. doi: 10.1016/j.bbagrm.2019.07.004. [Epub ahead of print] Review.

PMID:
31323435
2.

A novel role of U1 snRNP: Splice site selection from a distance.

Singh RN, Singh NN.

Biochim Biophys Acta Gene Regul Mech. 2019 Jun;1862(6):634-642. doi: 10.1016/j.bbagrm.2019.04.004. Epub 2019 Apr 28. Review.

PMID:
31042550
3.

Human Survival Motor Neuron genes generate a vast repertoire of circular RNAs.

Ottesen EW, Luo D, Seo J, Singh NN, Singh RN.

Nucleic Acids Res. 2019 Apr 8;47(6):2884-2905. doi: 10.1093/nar/gkz034.

4.

Correction: Journey to the east: Diverse routes and variable flowering times for wheat and barley en route to prehistoric China.

Liu X, Lister DL, Zhao Z, Petrie CA, Zeng X, Jones PJ, Staff RA, Pokharia AK, Bates J, Singh RN, Weber SA, Matuzeviciute GM, Dong G, Li H, Lü H, Jiang H, Wang J, Ma J, Tian D, Jin G, Zhou L, Wu X, Jones MK.

PLoS One. 2018 Dec 13;13(12):e0209518. doi: 10.1371/journal.pone.0209518. eCollection 2018.

5.

Large-Scale Preparation of Extracellular Vesicles Enriched with Specific microRNA.

Yoo KW, Li N, Makani V, Singh RN, Atala A, Lu B.

Tissue Eng Part C Methods. 2018 Nov;24(11):637-644. doi: 10.1089/ten.TEC.2018.0249. Epub 2018 Nov 2.

PMID:
30306827
6.

Pre-mRNA Splicing Modulation by Antisense Oligonucleotides.

Singh NN, Luo D, Singh RN.

Methods Mol Biol. 2018;1828:415-437. doi: 10.1007/978-1-4939-8651-4_26.

7.

High-affinity RNA targets of the Survival Motor Neuron protein reveal diverse preferences for sequence and structural motifs.

Ottesen EW, Singh NN, Luo D, Singh RN.

Nucleic Acids Res. 2018 Nov 16;46(20):10983-11001. doi: 10.1093/nar/gky770.

8.

Author Correction: Intensified summer monsoon and the urbanization of Indus Civilization in northwest India.

Dixit Y, Hodell DA, Giesche A, Tandon SK, Gázquez F, Saini HS, Skinner LC, Mujtaba SAI, Pawar V, Singh RN, Petrie CA.

Sci Rep. 2018 Aug 3;8(1):11711. doi: 10.1038/s41598-018-30084-7.

9.

Mechanism of Splicing Regulation of Spinal Muscular Atrophy Genes.

Singh RN, Singh NN.

Adv Neurobiol. 2018;20:31-61. doi: 10.1007/978-3-319-89689-2_2. Review.

10.

Intensified summer monsoon and the urbanization of Indus Civilization in northwest India.

Dixit Y, Hodell DA, Giesche A, Tandon SK, Gázquez F, Saini HS, Skinner LC, Mujtaba SAI, Pawar V, Singh RN, Petrie CA.

Sci Rep. 2018 Mar 9;8(1):4225. doi: 10.1038/s41598-018-22504-5. Erratum in: Sci Rep. 2018 Aug 3;8(1):11711.

11.

Nanodiamonds facilitate killing of intracellular uropathogenic E. coli in an in vitro model of urinary tract infection pathogenesis.

Iyer JK, Dickey A, Rouhani P, Kaul A, Govindaraju N, Singh RN, Kaul R.

PLoS One. 2018 Jan 11;13(1):e0191020. doi: 10.1371/journal.pone.0191020. eCollection 2018.

12.

A Multilayered Control of the Human Survival Motor Neuron Gene Expression by Alu Elements.

Ottesen EW, Seo J, Singh NN, Singh RN.

Front Microbiol. 2017 Nov 15;8:2252. doi: 10.3389/fmicb.2017.02252. eCollection 2017. Review.

13.

Journey to the east: Diverse routes and variable flowering times for wheat and barley en route to prehistoric China.

Liu X, Lister DL, Zhao Z, Petrie CA, Zeng X, Jones PJ, Staff RA, Pokharia AK, Bates J, Singh RN, Weber SA, Motuzaite Matuzeviciute G, Dong G, Li H, Lü H, Jiang H, Wang J, Ma J, Tian D, Jin G, Zhou L, Wu X, Jones MK.

PLoS One. 2017 Nov 2;12(11):e0187405. doi: 10.1371/journal.pone.0187405. eCollection 2017. Erratum in: PLoS One. 2018 Dec 13;13(12):e0209518.

14.

MEX3C interacts with adaptor-related protein complex 2 and involves in miR-451a exosomal sorting.

Lu P, Li H, Li N, Singh RN, Bishop CE, Chen X, Lu B.

PLoS One. 2017 Oct 5;12(10):e0185992. doi: 10.1371/journal.pone.0185992. eCollection 2017.

15.

Activation of a cryptic 5' splice site reverses the impact of pathogenic splice site mutations in the spinal muscular atrophy gene.

Singh NN, Del Rio-Malewski JB, Luo D, Ottesen EW, Howell MD, Singh RN.

Nucleic Acids Res. 2017 Dec 1;45(21):12214-12240. doi: 10.1093/nar/gkx824.

16.

Bacterial communities in ancient permafrost profiles of Svalbard, Arctic.

Singh P, Singh SM, Singh RN, Naik S, Roy U, Srivastava A, Bölter M.

J Basic Microbiol. 2017 Dec;57(12):1018-1036. doi: 10.1002/jobm.201700061. Epub 2017 Sep 21.

PMID:
28940222
17.

TIA1 is a gender-specific disease modifier of a mild mouse model of spinal muscular atrophy.

Howell MD, Ottesen EW, Singh NN, Anderson RL, Seo J, Sivanesan S, Whitley EM, Singh RN.

Sci Rep. 2017 Aug 3;7(1):7183. doi: 10.1038/s41598-017-07468-2.

18.

How the discovery of ISS-N1 led to the first medical therapy for spinal muscular atrophy.

Singh NN, Howell MD, Androphy EJ, Singh RN.

Gene Ther. 2017 Sep;24(9):520-526. doi: 10.1038/gt.2017.34. Epub 2017 May 9. Review.

19.

A Retrospective Study on Mycophenolic Acid Drug Interactions: Effect of Prednisone, Sirolimus, and Tacrolimus With MPA.

Alvarez-Elías AC, Yoo EC, Todorova EK, Singh RN, Filler G.

Ther Drug Monit. 2017 Jun;39(3):220-228. doi: 10.1097/FTD.0000000000000403.

PMID:
28437284
20.

Gender-Specific Amelioration of SMA Phenotype upon Disruption of a Deep Intronic Structure by an Oligonucleotide.

Howell MD, Ottesen EW, Singh NN, Anderson RL, Singh RN.

Mol Ther. 2017 Jun 7;25(6):1328-1341. doi: 10.1016/j.ymthe.2017.03.036. Epub 2017 Apr 13.

21.

Evaluation of multiwalled carbon nanotube cytotoxicity in cultures of human brain microvascular endothelial cells grown on plastic or basement membrane.

Eldridge BN, Xing F, Fahrenholtz CD, Singh RN.

Toxicol In Vitro. 2017 Jun;41:223-231. doi: 10.1016/j.tiv.2017.03.002. Epub 2017 Mar 9.

22.

Antimycobacterial, antimicrobial activity, experimental (FT-IR, FT-Raman, NMR, UV-Vis, DSC) and DFT (transition state, chemical reactivity, NBO, NLO) studies on pyrrole-isonicotinyl hydrazine.

Rawat P, Singh RN, Ranjan A, Ahmad S, Saxena R.

Spectrochim Acta A Mol Biomol Spectrosc. 2017 May 15;179:1-10. doi: 10.1016/j.saa.2017.02.021. Epub 2017 Feb 11.

PMID:
28213139
23.

Draft Genome Sequence of Halolamina pelagica CDK2 Isolated from Natural Salterns from Rann of Kutch, Gujarat, India.

Gaba S, Singh RN, Abrol S, Yadav AN, Saxena AK, Kaushik R.

Genome Announc. 2017 Feb 9;5(6). pii: e01593-16. doi: 10.1128/genomeA.01593-16.

24.

Diverse role of survival motor neuron protein.

Singh RN, Howell MD, Ottesen EW, Singh NN.

Biochim Biophys Acta Gene Regul Mech. 2017 Mar;1860(3):299-315. doi: 10.1016/j.bbagrm.2016.12.008. Epub 2017 Jan 15. Review.

25.

Heterogeneous Responses of Ovarian Cancer Cells to Silver Nanoparticles as a Single Agent and in Combination with Cisplatin.

Fahrenholtz CD, Swanner J, Ramirez-Perez M, Singh RN.

J Nanomater. 2017;2017. pii: 5107485. doi: 10.1155/2017/5107485. Epub 2017 Apr 26.

26.

First high quality draft genome sequence of a plant growth promoting and cold active enzyme producing psychrotrophic Arthrobacter agilis strain L77.

Singh RN, Gaba S, Yadav AN, Gaur P, Gulati S, Kaushik R, Saxena AK.

Stand Genomic Sci. 2016 Aug 26;11(1):54. doi: 10.1186/s40793-016-0176-4. eCollection 2016.

27.

A novel human-specific splice isoform alters the critical C-terminus of Survival Motor Neuron protein.

Seo J, Singh NN, Ottesen EW, Lee BM, Singh RN.

Sci Rep. 2016 Aug 2;6:30778. doi: 10.1038/srep30778.

28.

Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene.

Seo J, Singh NN, Ottesen EW, Sivanesan S, Shishimorova M, Singh RN.

PLoS One. 2016 Apr 25;11(4):e0154390. doi: 10.1371/journal.pone.0154390. eCollection 2016.

29.

Purification and functionalization of nanodiamond to serve as a platform for amoxicillin delivery.

Rouhani P, Govindaraju N, Iyer JK, Kaul R, Kaul A, Singh RN.

Mater Sci Eng C Mater Biol Appl. 2016 Jun;63:323-32. doi: 10.1016/j.msec.2016.02.075. Epub 2016 Feb 27.

PMID:
27040226
30.

Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy.

Ottesen EW, Howell MD, Singh NN, Seo J, Whitley EM, Singh RN.

Sci Rep. 2016 Feb 2;6:20193. doi: 10.1038/srep20193.

31.

A Rare Presentation Of An Ectopic Breast Tissue In Axilla.

Vidyasagar R; Sudarshan, Singh RN; Shivaram.

Pol Przegl Chir. 2015 Oct;87(10):528-30. doi: 10.1515/pjs-2015-0099.

PMID:
26812754
32.

Antimicrobial activity, structural evaluation and vibrational (FT-IR and FT-Raman) study of pyrrole containing vinyl derivatives.

Singh RN, Rawat P, Sahu S, Kumar Y.

Spectrochim Acta A Mol Biomol Spectrosc. 2016 Feb 5;154:47-57. doi: 10.1016/j.saa.2015.09.032. Epub 2015 Oct 9.

PMID:
26513227
33.

Using simplified blood pressure tables to avoid underdiagnosing childhood hypertension.

Sharma AP, Mohammed J, Thomas B, Singh RN, Filler G.

Paediatr Child Health. 2015 Aug-Sep;20(6):297-301.

34.

Mechanistic principles of antisense targets for the treatment of spinal muscular atrophy.

Singh NN, Lee BM, DiDonato CJ, Singh RN.

Future Med Chem. 2015;7(13):1793-808. doi: 10.4155/fmc.15.101. Epub 2015 Sep 18. Review.

35.

Selection of alkalotolerant and symbiotically efficient chickpea nodulating rhizobia from North-West Indo Gangetic Plains.

Singh RP, Manchanda G, Singh RN, Srivastava AK, Dubey RC.

J Basic Microbiol. 2016 Jan;56(1):14-25. doi: 10.1002/jobm.201500267. Epub 2015 Sep 17.

PMID:
26377641
36.

Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells.

Swanner J, Mims J, Carroll DL, Akman SA, Furdui CM, Torti SV, Singh RN.

Int J Nanomedicine. 2015 Jun 11;10:3937-53. doi: 10.2147/IJN.S80349. eCollection 2015.

37.

Splicing regulation in spinal muscular atrophy by an RNA structure formed by long-distance interactions.

Singh NN, Lee BM, Singh RN.

Ann N Y Acad Sci. 2015 Apr;1341:176-87. doi: 10.1111/nyas.12727. Epub 2015 Feb 27.

38.

Assessment of conformational, spectral, antimicrobial activity, chemical reactivity and NLO application of Pyrrole-2,5-dicarboxaldehyde bis(oxaloyldihydrazone).

Rawat P, Singh RN.

Spectrochim Acta A Mol Biomol Spectrosc. 2015 Apr 5;140:344-55. doi: 10.1016/j.saa.2014.12.080. Epub 2014 Dec 25.

PMID:
25615679
39.

Early critical care course in children after liver transplant.

Kukreti V, Daoud H, Bola SS, Singh RN, Atkison P, Kornecki A.

Crit Care Res Pract. 2014;2014:725748. doi: 10.1155/2014/725748. Epub 2014 Sep 25.

41.

Advances in therapeutic development for spinal muscular atrophy.

Howell MD, Singh NN, Singh RN.

Future Med Chem. 2014 Jun;6(9):1081-99. doi: 10.4155/fmc.14.63. Review.

42.

A short antisense oligonucleotide ameliorates symptoms of severe mouse models of spinal muscular atrophy.

Keil JM, Seo J, Howell MD, Hsu WH, Singh RN, DiDonato CJ.

Mol Ther Nucleic Acids. 2014 Jul 8;3:e174. doi: 10.1038/mtna.2014.23.

43.

Food and feeding pattern of Channa punctatus in two different habitats at Tarai region of Uttarakhand.

Singh CP, Ram RN, Singh RN.

J Environ Biol. 2013 Jul;34(4):789-92.

PMID:
24640258
44.

Copper-iron-molybdenum mixed oxides as efficient oxygen evolution electrocatalysts.

Srirapu VK, Sharma CS, Awasthi R, Singh RN, Sinha AS.

Phys Chem Chem Phys. 2014 Apr 28;16(16):7385-93. doi: 10.1039/c3cp55453h.

PMID:
24623197
45.
46.

Antisense methods to modulate pre-mRNA splicing.

Seo J, Ottesen EW, Singh RN.

Methods Mol Biol. 2014;1126:271-83. doi: 10.1007/978-1-62703-980-2_20.

PMID:
24549671
47.

Diagnosis by peritoneal scintigraphy of peritoneal dialysis-associated hydrothorax in an infant.

Chavannes M, Sharma AP, Singh RN, Reid RH, Filler G.

Perit Dial Int. 2014 Jan-Feb;34(1):140-3. doi: 10.3747/pdi.2012.00077. No abstract available.

48.

Antisense oligonucleotide mediated therapy of spinal muscular atrophy.

Sivanesan S, Howell MD, Didonato CJ, Singh RN.

Transl Neurosci. 2013 Mar;4(1). doi: 10.2478/s13380-013-0109-2.

49.

Graphene-cobaltite-Pd hybrid materials for use as efficient bifunctional electrocatalysts in alkaline direct methanol fuel cells.

Sharma CS, Awasthi R, Singh RN, Sinha AS.

Phys Chem Chem Phys. 2013 Dec 14;15(46):20333-44. doi: 10.1039/c3cp53880j.

PMID:
24169732
50.

Phase transitions of perfluorocarbon nanoemulsion induced with ultrasound: a mathematical model.

Pitt WG, Singh RN, Perez KX, Husseini GA, Jack DR.

Ultrason Sonochem. 2014 Mar;21(2):879-91. doi: 10.1016/j.ultsonch.2013.08.005. Epub 2013 Aug 23.

PMID:
24035720

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