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Items: 1 to 50 of 94

1.

An ovarian spheroid based tumor model that represents vascularized tumors and enables the investigation of nanomedicine therapeutics.

Singh MS, Goldsmith M, Thakur K, Chatterjee S, Landesman-Milo D, Levy T, Kunz-Schughart LA, Barenholz Y, Peer D.

Nanoscale. 2020 Jan 23;12(3):1894-1903. doi: 10.1039/c9nr09572a.

PMID:
31904048
2.

Oral N-acetylcysteine improves cone function in retinitis pigmentosa patients in phase I trial.

Campochiaro PA, Iftikhar M, Hafiz G, Akhlaq A, Tsai G, Wehling D, Lu L, Wall GM, Singh MS, Kong X.

J Clin Invest. 2020 Feb 17. pii: 132990. doi: 10.1172/JCI132990. [Epub ahead of print]

3.

Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases.

Ong SS, Patel TP, Singh MS.

J Clin Med. 2019 Nov 28;8(12). pii: E2078. doi: 10.3390/jcm8122078. Review.

4.
5.

Choroidal Neovascularization Associated with Pentosan Polysulfate Toxicity.

Mishra K, Patel TP, Singh MS.

Ophthalmol Retina. 2020 Jan;4(1):111-113. doi: 10.1016/j.oret.2019.08.006. Epub 2019 Aug 23. No abstract available.

PMID:
31570285
6.

Retinal stem cell transplantation: Balancing safety and potential.

Singh MS, Park SS, Albini TA, Canto-Soler MV, Klassen H, MacLaren RE, Takahashi M, Nagiel A, Schwartz SD, Bharti K.

Prog Retin Eye Res. 2019 Sep 5:100779. doi: 10.1016/j.preteyeres.2019.100779. [Epub ahead of print] Review.

7.

Organocatalytic Domino Reaction of Spiroaziridine Oxindoles and Malononitrile for the Enantiopure Synthesis of Spiro[dihydropyrrole-3,3'-oxindoles].

Hajra S, Abu Saleh SK, Hazra A, Singh MS.

J Org Chem. 2019 Jun 21;84(12):8194-8201. doi: 10.1021/acs.joc.9b01226. Epub 2019 Jun 12.

PMID:
31142119
8.

Photoacoustic elastography imaging: a review.

Singh MS, Thomas A.

J Biomed Opt. 2019 Apr;24(4):1-15. doi: 10.1117/1.JBO.24.4.040902.

9.

Visible-Light-Mediated Synthesis of 1,2,4-Dithiazolidines from β-Ketothioamides through a Hydrogen-Atom-Transfer Photocatalytic Approach of Eosin Y.

Ansari MA, Yadav D, Soni S, Srivastava A, Singh MS.

J Org Chem. 2019 May 3;84(9):5404-5412. doi: 10.1021/acs.joc.9b00406. Epub 2019 Apr 17.

PMID:
30950618
10.

An AAV Dual Vector Strategy Ameliorates the Stargardt Phenotype in Adult Abca4-/- Mice.

McClements ME, Barnard AR, Singh MS, Charbel Issa P, Jiang Z, Radu RA, MacLaren RE.

Hum Gene Ther. 2019 May;30(5):590-600. doi: 10.1089/hum.2018.156. Epub 2018 Dec 24.

PMID:
30381971
11.

Stem Cell Treatment for Age-Related Macular Degeneration: the Challenges.

Singh MS, MacLaren RE.

Invest Ophthalmol Vis Sci. 2018 Mar 20;59(4):AMD78-AMD82. doi: 10.1167/iovs.18-24426. Review. No abstract available.

PMID:
30025109
12.

Metal-Free One-Pot Four-Component Cascade Annulation in Ionic Liquids at Room Temperature: Convergent Access to Thiazoloquinolinone Derivatives.

Singh A, Srivastava A, Singh MS.

J Org Chem. 2018 Aug 3;83(15):7950-7961. doi: 10.1021/acs.joc.8b00814. Epub 2018 Jul 16.

PMID:
29978705
13.

Inner retinal vasculopathy in Zika virus disease.

Singh MS, Marquezan MC, Omiadze R, Reddy AK, Belfort R Jr, May WN.

Am J Ophthalmol Case Rep. 2018 Jan 17;10:6-7. doi: 10.1016/j.ajoc.2018.01.023. eCollection 2018 Jun.

14.

Copper-Catalyzed One-Pot Cross-Dehydrogenative Thienannulation: Chemoselective Access to Naphtho[2,1-b]thiophene-4,5-diones and Subsequent Transformation to Benzo[a]thieno[3,2-c]phenazines.

Shukla G, Srivastava A, Yadav D, Singh MS.

J Org Chem. 2018 Feb 16;83(4):2173-2181. doi: 10.1021/acs.joc.7b03092. Epub 2018 Jan 26.

PMID:
29345936
15.

Increasing potential for intense tropical and subtropical thunderstorms under global warming.

Singh MS, Kuang Z, Maloney ED, Hannah WM, Wolding BO.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11657-11662. doi: 10.1073/pnas.1707603114. Epub 2017 Oct 16. Erratum in: Proc Natl Acad Sci U S A. 2018 Jan 2;:.

16.

Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy.

De Silva SR, Barnard AR, Hughes S, Tam SKE, Martin C, Singh MS, Barnea-Cramer AO, McClements ME, During MJ, Peirson SN, Hankins MW, MacLaren RE.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11211-11216. doi: 10.1073/pnas.1701589114. Epub 2017 Oct 2.

17.

Access to Fully Substituted Thiazoles and 2,3-Dihydrothiazoles via Copper-Catalyzed [4 + 1] Heterocyclization of α-(N-Hydroxy/aryl)imino-β-oxodithioesters with α-Diazocarbonyls.

Srivastava A, Shukla G, Yadav D, Singh MS.

J Org Chem. 2017 Oct 20;82(20):10846-10854. doi: 10.1021/acs.joc.7b01601. Epub 2017 Oct 2.

PMID:
28945080
18.

Endoscopic management of posterior ankle impingement syndrome-A case report.

Kumar J, Singh MS, Tandon S.

J Clin Orthop Trauma. 2017 Aug;8(Suppl 1):S21-S25. doi: 10.1016/j.jcot.2017.07.005. Epub 2017 Jul 21.

19.

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina.

Hickey DG, Edwards TL, Barnard AR, Singh MS, de Silva SR, McClements ME, Flannery JG, Hankins MW, MacLaren RE.

Gene Ther. 2017 Dec;24(12):787-800. doi: 10.1038/gt.2017.85. Epub 2017 Nov 16.

20.

MDR in cancer: Addressing the underlying cellular alterations with the use of nanocarriers.

Singh MS, Tammam SN, Shetab Boushehri MA, Lamprecht A.

Pharmacol Res. 2017 Dec;126:2-30. doi: 10.1016/j.phrs.2017.07.023. Epub 2017 Jul 29. Review.

PMID:
28760489
21.

PARS PLANA VITRECTOMY AND LENSECTOMY FOR ECTOPIA LENTIS WITH AND WITHOUT THE INDUCTION OF A POSTERIOR VITREOUS DETACHMENT.

Singh MS, Casswell EJ, Boukouvala S, Petrou P, Charteris DG.

Retina. 2018 Feb;38(2):325-330. doi: 10.1097/IAE.0000000000001534.

PMID:
28207607
22.

Emerging therapies for inherited retinal degeneration.

Scholl HP, Strauss RW, Singh MS, Dalkara D, Roska B, Picaud S, Sahel JA.

Sci Transl Med. 2016 Dec 7;8(368):368rv6. Review.

PMID:
27928030
23.

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion.

Singh MS, Balmer J, Barnard AR, Aslam SA, Moralli D, Green CM, Barnea-Cramer A, Duncan I, MacLaren RE.

Nat Commun. 2016 Nov 30;7:13537. doi: 10.1038/ncomms13537.

24.

Switching Selectivity of α-Enolic Dithioesters: One Pot Access to Functionalized 1,2- and 1,3-Dithioles.

Koley S, Chanda T, Samai S, Singh MS.

J Org Chem. 2016 Dec 2;81(23):11594-11602. Epub 2016 Nov 17.

PMID:
27813414
25.

Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo.

De Silva SR, Charbel Issa P, Singh MS, Lipinski DM, Barnea-Cramer AO, Walker NJ, Barnard AR, Hankins MW, MacLaren RE.

Gene Ther. 2016 Nov;23(11):767-774. doi: 10.1038/gt.2016.54. Epub 2016 Jul 14.

26.

The effect of endothelin A and B receptor blockade on cutaneous vascular and sweating responses in young men during and following exercise in the heat.

Fujii N, Singh MS, Halili L, Louie JC, Kenny GP.

J Appl Physiol (1985). 2016 Dec 1;121(6):1263-1271. doi: 10.1152/japplphysiol.00679.2016. Epub 2016 Oct 7.

27.

Developments toward the synthesis and application of 3-hydroxyindanones.

Chanda T, Singh MS.

Org Biomol Chem. 2016 Sep 26;14(38):8895-8910. Review.

PMID:
27714251
28.

Evaluation of an Optimized Injection System for Retinal Gene Therapy in Human Patients.

Fischer MD, Hickey DG, Singh MS, MacLaren RE.

Hum Gene Ther Methods. 2016 Aug;27(4):150-8. doi: 10.1089/hgtb.2016.086.

PMID:
27480111
29.

Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice.

Barnea-Cramer AO, Wang W, Lu SJ, Singh MS, Luo C, Huo H, McClements ME, Barnard AR, MacLaren RE, Lanza R.

Sci Rep. 2016 Jul 13;6:29784. doi: 10.1038/srep29784.

30.

p-TSA/Base-Promoted Propargylation/Cyclization of β-Ketothioamides for the Regioselective Synthesis of Highly Substituted (Hydro)thiophenes.

Nandi GC, Singh MS.

J Org Chem. 2016 Jul 15;81(14):5824-36. doi: 10.1021/acs.joc.6b00342. Epub 2016 Jun 30.

PMID:
27327276
31.

Hypotrichosis and juvenile macular dystrophy caused by CDH3 mutation: A candidate disease for retinal gene therapy.

Singh MS, Broadgate S, Mathur R, Holt R, Halford S, MacLaren RE.

Sci Rep. 2016 May 9;6:23674. doi: 10.1038/srep23674.

32.

Metal- and Catalyst-Free, Formal [4 + 1] Annulation via Tandem C═O/C═S Functionalization: One-Pot Access to 3,5-Disubstituted/Annulated Isothiazoles.

Shukla G, Srivastava A, Singh MS.

Org Lett. 2016 May 20;18(10):2451-4. doi: 10.1021/acs.orglett.6b00997. Epub 2016 May 5.

PMID:
27149251
33.

Cutaneous vascular and sweating responses to intradermal administration of prostaglandin E1 and E2 in young and older adults: a role for nitric oxide?

Fujii N, Singh MS, Halili L, Boulay P, Sigal RJ, Kenny GP.

Am J Physiol Regul Integr Comp Physiol. 2016 Jun 1;310(11):R1064-72. doi: 10.1152/ajpregu.00538.2015. Epub 2016 Apr 13.

34.

Endothelin-1 modulates methacholine-induced cutaneous vasodilatation but not sweating in young human skin.

Halili L, Singh MS, Fujii N, Alexander LM, Kenny GP.

J Physiol. 2016 Jun 15;594(12):3439-52. doi: 10.1113/JP271735. Epub 2016 Mar 11.

35.

RNA nanomedicines: the next generation drugs?

Singh MS, Peer D.

Curr Opin Biotechnol. 2016 Jun;39:28-34. doi: 10.1016/j.copbio.2015.12.011. Epub 2016 Jan 11. Review.

PMID:
26773301
36.

siRNA delivery: current trends and future perspectives.

Singh MS, Peer D.

Ther Deliv. 2016;7(2):51-3. doi: 10.4155/tde.15.88. Epub 2016 Jan 15. No abstract available.

37.
38.

Metal-free aerobic one-pot synthesis of substituted/annulated quinolines from alcohols via indirect Friedländer annulation.

Anand N, Koley S, Ramulu BJ, Singh MS.

Org Biomol Chem. 2015 Oct 7;13(37):9570-4. doi: 10.1039/c5ob01422k.

PMID:
26316322
39.

Intradermal administration of ATP augments methacholine-induced cutaneous vasodilation but not sweating in young males and females.

Fujii N, Halili L, Singh MS, Meade RD, Kenny GP.

Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15;309(8):R912-9. doi: 10.1152/ajpregu.00261.2015. Epub 2015 Aug 19.

40.

Poor mobility predicts adverse outcome better than other frailty indices in patients undergoing transcatheter aortic valve implantation.

Cockburn J, Singh MS, Rafi NH, Dooley M, Hutchinson N, Hill A, Trivedi U, de Belder A, Hildick-Smith D.

Catheter Cardiovasc Interv. 2015 Dec 1;86(7):1271-7. doi: 10.1002/ccd.25991. Epub 2015 Jun 29.

PMID:
26119601
41.

P-glycoprotein inhibition of drug resistant cell lines by nanoparticles.

Singh MS, Lamprecht A.

Drug Dev Ind Pharm. 2016;42(2):325-31. doi: 10.3109/03639045.2015.1054396. Epub 2015 Jun 11.

PMID:
26065532
42.

Evaluation of dual P-gp-BCRP inhibitors as nanoparticle formulation.

Singh MS, Juvale K, Wiese M, Lamprecht A.

Eur J Pharm Sci. 2015 Sep 18;77:1-8. doi: 10.1016/j.ejps.2015.04.027. Epub 2015 May 12.

PMID:
25976226
43.

CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa.

Lipinski DM, Barnard AR, Singh MS, Martin C, Lee EJ, Davies WIL, MacLaren RE.

Mol Ther. 2015 Aug;23(8):1308-1319. doi: 10.1038/mt.2015.68. Epub 2015 Apr 21.

44.

Subretinal Visual Implant Alpha IMS--Clinical trial interim report.

Stingl K, Bartz-Schmidt KU, Besch D, Chee CK, Cottriall CL, Gekeler F, Groppe M, Jackson TL, MacLaren RE, Koitschev A, Kusnyerik A, Neffendorf J, Nemeth J, Naeem MA, Peters T, Ramsden JD, Sachs H, Simpson A, Singh MS, Wilhelm B, Wong D, Zrenner E.

Vision Res. 2015 Jun;111(Pt B):149-60. doi: 10.1016/j.visres.2015.03.001. Epub 2015 Mar 23.

45.

Cutaneous vascular and sweating responses to intradermal administration of ATP: a role for nitric oxide synthase and cyclooxygenase?

Fujii N, McGinn R, Halili L, Singh MS, Kondo N, Kenny GP.

J Physiol. 2015 Jun 1;593(11):2515-25. doi: 10.1113/JP270147. Epub 2015 Apr 17.

46.

Cargoing P-gp inhibitors via nanoparticle sensitizes tumor cells against doxorubicin.

Singh MS, Lamprecht A.

Int J Pharm. 2015 Jan 30;478(2):745-52. doi: 10.1016/j.ijpharm.2014.11.064. Epub 2014 Nov 28.

PMID:
25437111
47.

Regioselective synthesis of dihydrothiophene and thiopyran frameworks via catalyst-controlled intramolecular Cγ/Cδ-S fusion of α-allyl-β'-oxodithioesters.

Chowdhury S, Chanda T, Koley S, Anand N, Singh MS.

Org Lett. 2014 Nov 7;16(21):5536-9. doi: 10.1021/ol502850h. Epub 2014 Oct 24.

PMID:
25343754
48.

Lewis acid promoted construction of chromen-4-one and isoflavone scaffolds via regio- and chemoselective domino Friedel-Crafts acylation/Allan-Robinson reaction.

Chanda T, Chowdhury S, Koley S, Anand N, Singh MS.

Org Biomol Chem. 2014 Dec 7;12(45):9216-22. doi: 10.1039/c4ob01743a.

PMID:
25299841
49.

Pleomorphic xanthoastrocytoma in a case of tuberous sclerosis.

Martin AG, Singh MS, Idris B, Abdullah JM.

J Neurosci Rural Pract. 2014 Jul;5(3):258-60. doi: 10.4103/0976-3147.133580.

50.

Elastic property attributes to photoacoustic signals: an experimental phantom study.

Singh MS, Jiang H.

Opt Lett. 2014 Jul 1;39(13):3970-3. doi: 10.1364/OL.39.003970.

PMID:
24978784

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