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Items: 1 to 50 of 84

1.

Stem Cell Treatment for Age-Related Macular Degeneration: the Challenges.

Singh MS, MacLaren RE.

Invest Ophthalmol Vis Sci. 2018 Mar 20;59(4):AMD78-AMD82. doi: 10.1167/iovs.18-24426. Review. No abstract available.

PMID:
30025109
2.

Metal-Free One-Pot Four-Component Cascade Annulation in Ionic Liquids at Room Temperature: Convergent Access to Thiazoloquinolinone Derivatives.

Singh A, Srivastava A, Singh MS.

J Org Chem. 2018 Aug 3;83(15):7950-7961. doi: 10.1021/acs.joc.8b00814. Epub 2018 Jul 16.

PMID:
29978705
3.

Inner retinal vasculopathy in Zika virus disease.

Singh MS, Marquezan MC, Omiadze R, Reddy AK, Belfort R Jr, May WN.

Am J Ophthalmol Case Rep. 2018 Jan 17;10:6-7. doi: 10.1016/j.ajoc.2018.01.023. eCollection 2018 Jun.

4.

Copper-Catalyzed One-Pot Cross-Dehydrogenative Thienannulation: Chemoselective Access to Naphtho[2,1-b]thiophene-4,5-diones and Subsequent Transformation to Benzo[a]thieno[3,2-c]phenazines.

Shukla G, Srivastava A, Yadav D, Singh MS.

J Org Chem. 2018 Feb 16;83(4):2173-2181. doi: 10.1021/acs.joc.7b03092. Epub 2018 Jan 26.

PMID:
29345936
5.

Increasing potential for intense tropical and subtropical thunderstorms under global warming.

Singh MS, Kuang Z, Maloney ED, Hannah WM, Wolding BO.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11657-11662. doi: 10.1073/pnas.1707603114. Epub 2017 Oct 16. Erratum in: Proc Natl Acad Sci U S A. 2018 Jan 2;:.

6.

Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy.

De Silva SR, Barnard AR, Hughes S, Tam SKE, Martin C, Singh MS, Barnea-Cramer AO, McClements ME, During MJ, Peirson SN, Hankins MW, MacLaren RE.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11211-11216. doi: 10.1073/pnas.1701589114. Epub 2017 Oct 2.

7.

Access to Fully Substituted Thiazoles and 2,3-Dihydrothiazoles via Copper-Catalyzed [4 + 1] Heterocyclization of α-(N-Hydroxy/aryl)imino-β-oxodithioesters with α-Diazocarbonyls.

Srivastava A, Shukla G, Yadav D, Singh MS.

J Org Chem. 2017 Oct 20;82(20):10846-10854. doi: 10.1021/acs.joc.7b01601. Epub 2017 Oct 2.

PMID:
28945080
8.

Endoscopic management of posterior ankle impingement syndrome-A case report.

Kumar J, Singh MS, Tandon S.

J Clin Orthop Trauma. 2017 Aug;8(Suppl 1):S21-S25. doi: 10.1016/j.jcot.2017.07.005. Epub 2017 Jul 21.

9.

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina.

Hickey DG, Edwards TL, Barnard AR, Singh MS, de Silva SR, McClements ME, Flannery JG, Hankins MW, MacLaren RE.

Gene Ther. 2017 Dec;24(12):787-800. doi: 10.1038/gt.2017.85. Epub 2017 Nov 16.

10.

MDR in cancer: Addressing the underlying cellular alterations with the use of nanocarriers.

Singh MS, Tammam SN, Shetab Boushehri MA, Lamprecht A.

Pharmacol Res. 2017 Dec;126:2-30. doi: 10.1016/j.phrs.2017.07.023. Epub 2017 Jul 29. Review.

PMID:
28760489
11.

PARS PLANA VITRECTOMY AND LENSECTOMY FOR ECTOPIA LENTIS WITH AND WITHOUT THE INDUCTION OF A POSTERIOR VITREOUS DETACHMENT.

Singh MS, Casswell EJ, Boukouvala S, Petrou P, Charteris DG.

Retina. 2018 Feb;38(2):325-330. doi: 10.1097/IAE.0000000000001534.

PMID:
28207607
12.

Emerging therapies for inherited retinal degeneration.

Scholl HP, Strauss RW, Singh MS, Dalkara D, Roska B, Picaud S, Sahel JA.

Sci Transl Med. 2016 Dec 7;8(368):368rv6. Review.

PMID:
27928030
13.

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion.

Singh MS, Balmer J, Barnard AR, Aslam SA, Moralli D, Green CM, Barnea-Cramer A, Duncan I, MacLaren RE.

Nat Commun. 2016 Nov 30;7:13537. doi: 10.1038/ncomms13537.

14.

Switching Selectivity of α-Enolic Dithioesters: One Pot Access to Functionalized 1,2- and 1,3-Dithioles.

Koley S, Chanda T, Samai S, Singh MS.

J Org Chem. 2016 Dec 2;81(23):11594-11602. Epub 2016 Nov 17.

PMID:
27813414
15.

Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo.

De Silva SR, Charbel Issa P, Singh MS, Lipinski DM, Barnea-Cramer AO, Walker NJ, Barnard AR, Hankins MW, MacLaren RE.

Gene Ther. 2016 Nov;23(11):767-774. doi: 10.1038/gt.2016.54. Epub 2016 Jul 14.

16.

The effect of endothelin A and B receptor blockade on cutaneous vascular and sweating responses in young men during and following exercise in the heat.

Fujii N, Singh MS, Halili L, Louie JC, Kenny GP.

J Appl Physiol (1985). 2016 Dec 1;121(6):1263-1271. doi: 10.1152/japplphysiol.00679.2016. Epub 2016 Oct 7.

17.

Developments toward the synthesis and application of 3-hydroxyindanones.

Chanda T, Singh MS.

Org Biomol Chem. 2016 Sep 26;14(38):8895-8910. Review.

PMID:
27714251
18.

Evaluation of an Optimized Injection System for Retinal Gene Therapy in Human Patients.

Fischer MD, Hickey DG, Singh MS, MacLaren RE.

Hum Gene Ther Methods. 2016 Aug;27(4):150-8. doi: 10.1089/hgtb.2016.086.

PMID:
27480111
19.

Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice.

Barnea-Cramer AO, Wang W, Lu SJ, Singh MS, Luo C, Huo H, McClements ME, Barnard AR, MacLaren RE, Lanza R.

Sci Rep. 2016 Jul 13;6:29784. doi: 10.1038/srep29784.

20.

p-TSA/Base-Promoted Propargylation/Cyclization of β-Ketothioamides for the Regioselective Synthesis of Highly Substituted (Hydro)thiophenes.

Nandi GC, Singh MS.

J Org Chem. 2016 Jul 15;81(14):5824-36. doi: 10.1021/acs.joc.6b00342. Epub 2016 Jun 30.

PMID:
27327276
21.

Hypotrichosis and juvenile macular dystrophy caused by CDH3 mutation: A candidate disease for retinal gene therapy.

Singh MS, Broadgate S, Mathur R, Holt R, Halford S, MacLaren RE.

Sci Rep. 2016 May 9;6:23674. doi: 10.1038/srep23674.

22.

Metal- and Catalyst-Free, Formal [4 + 1] Annulation via Tandem C═O/C═S Functionalization: One-Pot Access to 3,5-Disubstituted/Annulated Isothiazoles.

Shukla G, Srivastava A, Singh MS.

Org Lett. 2016 May 20;18(10):2451-4. doi: 10.1021/acs.orglett.6b00997. Epub 2016 May 5.

PMID:
27149251
23.

Cutaneous vascular and sweating responses to intradermal administration of prostaglandin E1 and E2 in young and older adults: a role for nitric oxide?

Fujii N, Singh MS, Halili L, Boulay P, Sigal RJ, Kenny GP.

Am J Physiol Regul Integr Comp Physiol. 2016 Jun 1;310(11):R1064-72. doi: 10.1152/ajpregu.00538.2015. Epub 2016 Apr 13.

24.

Endothelin-1 modulates methacholine-induced cutaneous vasodilatation but not sweating in young human skin.

Halili L, Singh MS, Fujii N, Alexander LM, Kenny GP.

J Physiol. 2016 Jun 15;594(12):3439-52. doi: 10.1113/JP271735. Epub 2016 Mar 11.

25.

RNA nanomedicines: the next generation drugs?

Singh MS, Peer D.

Curr Opin Biotechnol. 2016 Jun;39:28-34. doi: 10.1016/j.copbio.2015.12.011. Epub 2016 Jan 11. Review.

PMID:
26773301
26.

siRNA delivery: current trends and future perspectives.

Singh MS, Peer D.

Ther Deliv. 2016;7(2):51-3. doi: 10.4155/tde.15.88. Epub 2016 Jan 15. No abstract available.

27.
28.

Metal-free aerobic one-pot synthesis of substituted/annulated quinolines from alcohols via indirect Friedländer annulation.

Anand N, Koley S, Ramulu BJ, Singh MS.

Org Biomol Chem. 2015 Oct 7;13(37):9570-4. doi: 10.1039/c5ob01422k.

PMID:
26316322
29.

Intradermal administration of ATP augments methacholine-induced cutaneous vasodilation but not sweating in young males and females.

Fujii N, Halili L, Singh MS, Meade RD, Kenny GP.

Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15;309(8):R912-9. doi: 10.1152/ajpregu.00261.2015. Epub 2015 Aug 19.

30.

Poor mobility predicts adverse outcome better than other frailty indices in patients undergoing transcatheter aortic valve implantation.

Cockburn J, Singh MS, Rafi NH, Dooley M, Hutchinson N, Hill A, Trivedi U, de Belder A, Hildick-Smith D.

Catheter Cardiovasc Interv. 2015 Dec 1;86(7):1271-7. doi: 10.1002/ccd.25991. Epub 2015 Jun 29.

PMID:
26119601
31.

P-glycoprotein inhibition of drug resistant cell lines by nanoparticles.

Singh MS, Lamprecht A.

Drug Dev Ind Pharm. 2016;42(2):325-31. doi: 10.3109/03639045.2015.1054396. Epub 2015 Jun 11.

PMID:
26065532
32.

Evaluation of dual P-gp-BCRP inhibitors as nanoparticle formulation.

Singh MS, Juvale K, Wiese M, Lamprecht A.

Eur J Pharm Sci. 2015 Sep 18;77:1-8. doi: 10.1016/j.ejps.2015.04.027. Epub 2015 May 12.

PMID:
25976226
33.

CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa.

Lipinski DM, Barnard AR, Singh MS, Martin C, Lee EJ, Davies WIL, MacLaren RE.

Mol Ther. 2015 Aug;23(8):1308-1319. doi: 10.1038/mt.2015.68. Epub 2015 Apr 21.

34.

Subretinal Visual Implant Alpha IMS--Clinical trial interim report.

Stingl K, Bartz-Schmidt KU, Besch D, Chee CK, Cottriall CL, Gekeler F, Groppe M, Jackson TL, MacLaren RE, Koitschev A, Kusnyerik A, Neffendorf J, Nemeth J, Naeem MA, Peters T, Ramsden JD, Sachs H, Simpson A, Singh MS, Wilhelm B, Wong D, Zrenner E.

Vision Res. 2015 Jun;111(Pt B):149-60. doi: 10.1016/j.visres.2015.03.001. Epub 2015 Mar 23.

35.

Cutaneous vascular and sweating responses to intradermal administration of ATP: a role for nitric oxide synthase and cyclooxygenase?

Fujii N, McGinn R, Halili L, Singh MS, Kondo N, Kenny GP.

J Physiol. 2015 Jun 1;593(11):2515-25. doi: 10.1113/JP270147. Epub 2015 Apr 17.

36.

Cargoing P-gp inhibitors via nanoparticle sensitizes tumor cells against doxorubicin.

Singh MS, Lamprecht A.

Int J Pharm. 2015 Jan 30;478(2):745-52. doi: 10.1016/j.ijpharm.2014.11.064. Epub 2014 Nov 28.

PMID:
25437111
37.

Regioselective synthesis of dihydrothiophene and thiopyran frameworks via catalyst-controlled intramolecular Cγ/Cδ-S fusion of α-allyl-β'-oxodithioesters.

Chowdhury S, Chanda T, Koley S, Anand N, Singh MS.

Org Lett. 2014 Nov 7;16(21):5536-9. doi: 10.1021/ol502850h. Epub 2014 Oct 24.

PMID:
25343754
38.

Lewis acid promoted construction of chromen-4-one and isoflavone scaffolds via regio- and chemoselective domino Friedel-Crafts acylation/Allan-Robinson reaction.

Chanda T, Chowdhury S, Koley S, Anand N, Singh MS.

Org Biomol Chem. 2014 Dec 7;12(45):9216-22. doi: 10.1039/c4ob01743a.

PMID:
25299841
39.

Pleomorphic xanthoastrocytoma in a case of tuberous sclerosis.

Martin AG, Singh MS, Idris B, Abdullah JM.

J Neurosci Rural Pract. 2014 Jul;5(3):258-60. doi: 10.4103/0976-3147.133580.

40.

Elastic property attributes to photoacoustic signals: an experimental phantom study.

Singh MS, Jiang H.

Opt Lett. 2014 Jul 1;39(13):3970-3. doi: 10.1364/OL.39.003970.

PMID:
24978784
41.

In(OTf)3-catalysed one-pot versatile pyrrole synthesis through domino annulation of α-oxoketene-N,S-acetals with nitroolefins.

Srivastava A, Shukla G, Nagaraju A, Verma GK, Raghuvanshi K, Jones RC, Singh MS.

Org Biomol Chem. 2014 Aug 7;12(29):5484-91. doi: 10.1039/c4ob00781f.

PMID:
24942816
42.
43.

Nanocarrier-based immunotherapy in cancer management and research.

Singh MS, Bhaskar S.

Immunotargets Ther. 2014 Jun 26;3:121-34. doi: 10.2147/ITT.S62471. eCollection 2014. Review.

44.

Vesicular stomatitis virus glycoprotein- and Venezuelan equine encephalitis virus-derived glycoprotein-pseudotyped lentivirus vectors differentially transduce corneal endothelium, trabecular meshwork, and human photoreceptors.

Lipinski DM, Barnard AR, Charbel Issa P, Singh MS, De Silva SR, Trabalza A, Eleftheriadou I, Ellison SM, Mazarakis ND, MacLaren RE.

Hum Gene Ther. 2014 Jan;25(1):50-62. doi: 10.1089/hum.2013.009. Epub 2013 Dec 21.

PMID:
24125177
45.

Palladium catalyzed oxidative coupling of α-enolic dithioesters: a new entry to 3,4,5-trisubstituted 1,2-dithioles via a double activation strategy.

Chowdhury S, Chanda T, Koley S, Ramulu BJ, Jones RC, Singh MS.

Org Lett. 2013 Oct 18;15(20):5386-9. doi: 10.1021/ol402728y. Epub 2013 Oct 8.

PMID:
24102392
46.

Fundus autofluorescence in the Abca4(-/-) mouse model of Stargardt disease--correlation with accumulation of A2E, retinal function, and histology.

Charbel Issa P, Barnard AR, Singh MS, Carter E, Jiang Z, Radu RA, Schraermeyer U, MacLaren RE.

Invest Ophthalmol Vis Sci. 2013 Aug 19;54(8):5602-12. doi: 10.1167/iovs.13-11688.

47.

Cone photoreceptor neuroprotection conferred by CNTF in a novel in vivo model of battlefield retinal laser injury.

Aslam SA, Davies WI, Singh MS, Charbel Issa P, Barnard AR, Scott RA, MacLaren RE.

Invest Ophthalmol Vis Sci. 2013 Aug 13;54(8):5456-65. doi: 10.1167/iovs.13-11623.

PMID:
23744998
48.

Assessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retina.

Charbel Issa P, De Silva SR, Lipinski DM, Singh MS, Mouravlev A, You Q, Barnard AR, Hankins MW, During MJ, Maclaren RE.

PLoS One. 2013 Apr 9;8(4):e60361. doi: 10.1371/journal.pone.0060361. Print 2013.

49.

Nanoparticle mediated co-delivery of paclitaxel and a TLR-4 agonist results in tumor regression and enhanced immune response in the tumor microenvironment of a mouse model.

Roy A, Singh MS, Upadhyay P, Bhaskar S.

Int J Pharm. 2013 Mar 10;445(1-2):171-80. doi: 10.1016/j.ijpharm.2013.01.045. Epub 2013 Jan 30.

PMID:
23376226
50.

Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation.

Singh MS, Charbel Issa P, Butler R, Martin C, Lipinski DM, Sekaran S, Barnard AR, MacLaren RE.

Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):1101-6. doi: 10.1073/pnas.1119416110. Epub 2013 Jan 3.

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