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Antifungal Activity of the Enterococcus faecalis Peptide EntV Requires Protease Cleavage and Disulfide Bond Formation.

Brown AO, Graham CE, Cruz MR, Singh KV, Murray BE, Lorenz MC, Garsin DA.

MBio. 2019 Jul 2;10(4). pii: e01334-19. doi: 10.1128/mBio.01334-19.


Disrupting Membrane Adaptation Restores In Vivo Efficacy of Antibiotics Against Multidrug-Resistant Enterococci and Potentiates Killing by Human Neutrophils.

Rincon S, Panesso D, Miller WR, Singh KV, Cruz MR, Khan A, Dinh AQ, Diaz L, Rios R, Shamoo Y, Reyes J, Tran TT, Garsin DA, Arias CA.

J Infect Dis. 2019 Apr 2. pii: jiz131. doi: 10.1093/infdis/jiz131. [Epub ahead of print]


Loss of a Major Enterococcal Polysaccharide Antigen (Epa) by Enterococcus faecalis Is Associated with Increased Resistance to Ceftriaxone and Carbapenems.

Singh KV, Murray BE.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00481-19. doi: 10.1128/AAC.00481-19. Print 2019 May. No abstract available.


Efficacy of Tedizolid against Enterococci and Staphylococci, Including cfr + Strains, in a Mouse Peritonitis Model.

Singh KV, Arias CA, Murray BE.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02627-18. doi: 10.1128/AAC.02627-18. Print 2019 Apr.


Oxidative stress-mediated alterations on sperm parameters in male Wistar rats exposed to 3G mobile phone radiation.

Gautam R, Singh KV, Nirala J, Murmu NN, Meena R, Rajamani P.

Andrologia. 2019 Apr;51(3):e13201. doi: 10.1111/and.13201. Epub 2018 Nov 20.


Anti-Ace monoclonal antibody reduces Enterococcus faecalis aortic valve infection in a rat infective endocarditis model.

Singh KV, Pinkston KL, Gao P, Harvey BR, Murray BE.

Pathog Dis. 2018 Nov 1;76(8). doi: 10.1093/femspd/fty084.


Adjunctive Clavulanic Acid Abolishes the Cefazolin Inoculum Effect in an Experimental Rat Model of Methicillin-Sensitive Staphylococcus aureus Endocarditis.

Miller WR, Singh KV, Arias CA, Murray BE.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01158-18. doi: 10.1128/AAC.01158-18. Print 2018 Nov.


The Role of Fur in the Transcriptional and Iron Homeostatic Response of Enterococcus faecalis.

Latorre M, Quenti D, Travisany D, Singh KV, Murray BE, Maass A, Cambiazo V.

Front Microbiol. 2018 Jul 17;9:1580. doi: 10.3389/fmicb.2018.01580. eCollection 2018.


A Primary Jejunal Enterolith Presenting as Small Bowel Obstruction.

Singh MP, Huda T, Singh KV.

Indian J Surg. 2018 Jun;80(3):292-293. doi: 10.1007/s12262-018-1753-0. Epub 2018 Mar 9.


Influence of Inoculum Effect on the Efficacy of Daptomycin Monotherapy and in Combination with β-Lactams against Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions.

Kebriaei R, Rice SA, Singh KV, Stamper KC, Dinh AQ, Rios R, Diaz L, Murray BE, Munita JM, Tran TT, Arias CA, Rybak MJ.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00315-18. doi: 10.1128/AAC.00315-18. Print 2018 Aug.


Loss of Ethanolamine Utilization in Enterococcus faecalis Increases Gastrointestinal Tract Colonization.

Kaval KG, Singh KV, Cruz MR, DebRoy S, Winkler WC, Murray BE, Garsin DA.

MBio. 2018 May 8;9(3). pii: e00790-18. doi: 10.1128/mBio.00790-18.


Efficacy of Ceftaroline against Methicillin-Susceptible Staphylococcus aureus Exhibiting the Cefazolin High-Inoculum Effect in a Rat Model of Endocarditis.

Singh KV, Tran TT, Nannini EC, Tam VH, Arias CA, Murray BE.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e00324-17. doi: 10.1128/AAC.00324-17. Print 2017 Jul.


Efficacy of Telavancin Alone and in Combination with Ampicillin in a Rat Model of Enterococcus faecalis Endocarditis.

Tran TT, Tam VH, Murray BE, Arias CA, Singh KV.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02489-16. doi: 10.1128/AAC.02489-16. Print 2017 Jun.


Genomic confirmation of vancomycin-resistant Enterococcus transmission from deceased donor to liver transplant recipient.

Bashir A, Attie O, Sullivan M, Sebra R, Singh KV, Altman D, Pak T, Dutta J, Chacko K, Webster E, Lewis M, Hamula C, Delli Carpini KW, Murray BE, Kasarskis A, van Bakel H, Huprikar S.

PLoS One. 2017 Mar 16;12(3):e0170449. doi: 10.1371/journal.pone.0170449. eCollection 2017.


Improved prediction of missing protein interactome links via anomaly detection.

Singh KV, Vig L.

Appl Netw Sci. 2017;2(1):2. doi: 10.1007/s41109-017-0022-7. Epub 2017 Jan 28.


Antibody Guided Molecular Imaging of Infective Endocarditis.

Pinkston KL, Gao P, Singh KV, Azhdarinia A, Murray BE, Sevick-Muraca EM, Harvey BR.

Methods Mol Biol. 2017;1535:229-241.


Differential Penicillin-Binding Protein 5 (PBP5) Levels in the Enterococcus faecium Clades with Different Levels of Ampicillin Resistance.

Montealegre MC, Roh JH, Rae M, Davlieva MG, Singh KV, Shamoo Y, Murray BE.

Antimicrob Agents Chemother. 2016 Dec 27;61(1). pii: e02034-16. doi: 10.1128/AAC.02034-16. Print 2017 Jan.


Indomethacin injury to the rat small intestine is dependent upon biliary secretion and is associated with overgrowth of enterococci.

Mayo SA, Song YK, Cruz MR, Phan TM, Singh KV, Garsin DA, Murray BE, Dial EJ, Lichtenberger LM.

Physiol Rep. 2016 Mar;4(6). pii: e12725. doi: 10.14814/phy2.12725. Epub 2016 Mar 31.


Genome-wide Screening Identifies Phosphotransferase System Permease BepA to Be Involved in Enterococcus faecium Endocarditis and Biofilm Formation.

Paganelli FL, Huebner J, Singh KV, Zhang X, van Schaik W, Wobser D, Braat JC, Murray BE, Bonten MJ, Willems RJ, Leavis HL.

J Infect Dis. 2016 Jul 15;214(2):189-95. doi: 10.1093/infdis/jiw108. Epub 2016 Mar 16.


Enterococcus faecalis Ebp pili are important for cell-cell aggregation and intraspecies gene transfer.

La Rosa SL, Montealegre MC, Singh KV, Murray BE.

Microbiology. 2016 May;162(5):798-802. doi: 10.1099/mic.0.000276. Epub 2016 Mar 11.


Role of the Emp Pilus Subunits of Enterococcus faecium in Biofilm Formation, Adherence to Host Extracellular Matrix Components, and Experimental Infection.

Montealegre MC, Singh KV, Somarajan SR, Yadav P, Chang C, Spencer R, Sillanpää J, Ton-That H, Murray BE.

Infect Immun. 2016 Apr 22;84(5):1491-1500. doi: 10.1128/IAI.01396-15. Print 2016 May.


DNA barcoding Indian freshwater fishes.

Lakra WS, Singh M, Goswami M, Gopalakrishnan A, Lal KK, Mohindra V, Sarkar UK, Punia PP, Singh KV, Bhatt JP, Ayyappan S.

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 Nov;27(6):4510-4517. Epub 2015 Dec 24.


Gastrointestinal Tract Colonization Dynamics by Different Enterococcus faecium Clades.

Montealegre MC, Singh KV, Murray BE.

J Infect Dis. 2016 Jun 15;213(12):1914-22. doi: 10.1093/infdis/jiv597. Epub 2015 Dec 15.


The fibronectin-binding protein Fnm contributes to adherence to extracellular matrix components and virulence of Enterococcus faecium.

Somarajan SR, La Rosa SL, Singh KV, Roh JH, Höök M, Murray BE.

Infect Immun. 2015 Dec;83(12):4653-61. doi: 10.1128/IAI.00885-15. Epub 2015 Sep 14.


The fibronectin-binding protein EfbA contributes to pathogenesis and protects against infective endocarditis caused by Enterococcus faecalis.

Singh KV, La Rosa SL, Somarajan SR, Roh JH, Murray BE.

Infect Immun. 2015 Dec;83(12):4487-94. doi: 10.1128/IAI.00884-15. Epub 2015 Sep 8.


The identification and functional characterization of WxL proteins from Enterococcus faecium reveal surface proteins involved in extracellular matrix interactions.

Galloway-Peña JR, Liang X, Singh KV, Yadav P, Chang C, La Rosa SL, Shelburne S, Ton-That H, Höök M, Murray BE.

J Bacteriol. 2015 Mar;197(5):882-92. doi: 10.1128/JB.02288-14. Epub 2014 Dec 15.


The two-component system GrvRS (EtaRS) regulates ace expression in Enterococcus faecalis OG1RF.

Roh JH, Singh KV, La Rosa SL, Cohen AL, Murray BE.

Infect Immun. 2015 Jan;83(1):389-95. doi: 10.1128/IAI.02587-14. Epub 2014 Nov 10.


A liaR deletion restores susceptibility to daptomycin and antimicrobial peptides in multidrug-resistant Enterococcus faecalis.

Reyes J, Panesso D, Tran TT, Mishra NN, Cruz MR, Munita JM, Singh KV, Yeaman MR, Murray BE, Shamoo Y, Garsin D, Bayer AS, Arias CA.

J Infect Dis. 2015 Apr 15;211(8):1317-25. doi: 10.1093/infdis/jiu602. Epub 2014 Oct 31.


CcpA is important for growth and virulence of Enterococcus faecium.

Somarajan SR, Roh JH, Singh KV, Weinstock GM, Murray BE.

Infect Immun. 2014 Sep;82(9):3580-7. doi: 10.1128/IAI.01911-14. Epub 2014 Jun 9.


Influence of isolate origin and presence of various genes on biofilm formation by Enterococcus faecium.

Almohamad S, Somarajan SR, Singh KV, Nallapareddy SR, Murray BE.

FEMS Microbiol Lett. 2014 Apr;353(2):151-6. doi: 10.1111/1574-6968.12418. Epub 2014 Mar 24.


Hematological and serum biochemical profile of apparently healthy hariana cattle heifers in northern India.

Mahima, Singh KV, Verma AK, Kumar V, Singh SK, Roy D.

Pak J Biol Sci. 2013 Nov 1;16(21):1423-5.


Targeting pili in enterococcal pathogenesis.

Pinkston KL, Singh KV, Gao P, Wilganowski N, Robinson H, Ghosh S, Azhdarinia A, Sevick-Muraca EM, Murray BE, Harvey BR.

Infect Immun. 2014 Apr;82(4):1540-7. doi: 10.1128/IAI.01403-13. Epub 2014 Jan 22.


Efficacy of doramectin in Trixacarus caviae infestation in guinea pigs (Cavia porcellus).

Singh SK, Dimri U, Ahmed QS, Sayedda K, Singh KV.

J Parasit Dis. 2013 Apr;37(1):148-50. doi: 10.1007/s12639-012-0155-7. Epub 2012 Aug 17.


Contribution of individual Ebp Pilus subunits of Enterococcus faecalis OG1RF to pilus biogenesis, biofilm formation and urinary tract infection.

Sillanpää J, Chang C, Singh KV, Montealegre MC, Nallapareddy SR, Harvey BR, Ton-That H, Murray BE.

PLoS One. 2013 Jul 11;8(7):e68813. doi: 10.1371/journal.pone.0068813. Print 2013.


In Vivo Effects of Cefazolin, Daptomycin, and Nafcillin in Experimental Endocarditis with a Methicillin-Susceptible Staphylococcus aureus Strain Showing an Inoculum Effect against Cefazolin.

Nannini EC, Singh KV, Arias CA, Murray BE.

Antimicrob Agents Chemother. 2013 Sep;57(9):4276-4281. doi: 10.1128/AAC.00856-13. Epub 2013 Jun 24.


Dissecting the mechanisms of linezolid resistance in a Drosophila melanogaster infection model of Staphylococcus aureus.

Diaz L, Kontoyiannis DP, Panesso D, Albert ND, Singh KV, Tran TT, Munita JM, Murray BE, Arias CA.

J Infect Dis. 2013 Jul;208(1):83-91. doi: 10.1093/infdis/jit138. Epub 2013 Apr 1.


Development of a genomic site for gene integration and expression in Enterococcus faecalis.

Debroy S, van der Hoeven R, Singh KV, Gao P, Harvey BR, Murray BE, Garsin DA.

J Microbiol Methods. 2012 Jul;90(1):1-8. doi: 10.1016/j.mimet.2012.04.011. Epub 2012 Apr 18.


Changes in glucose-6-phosphate dehydrogenase activity in Indian desert malaria vector Anopheles stephensi during aging.

Mohanty SS, Singh KV, Bansal SK.

Acta Trop. 2012 Aug;123(2):132-5. doi: 10.1016/j.actatropica.2012.04.003. Epub 2012 Apr 20.


Transferable plasmid-mediated resistance to linezolid due to cfr in a human clinical isolate of Enterococcus faecalis.

Diaz L, Kiratisin P, Mendes RE, Panesso D, Singh KV, Arias CA.

Antimicrob Agents Chemother. 2012 Jul;56(7):3917-22. doi: 10.1128/AAC.00419-12. Epub 2012 Apr 9.


Efficacy of ceftobiprole Medocaril against Enterococcus faecalis in a murine urinary tract infection model.

Singh KV, Murray BE.

Antimicrob Agents Chemother. 2012 Jun;56(6):3457-60. doi: 10.1128/AAC.06102-11. Epub 2012 Mar 26.


Porcine and human community reservoirs of Enterococcus faecalis, Denmark.

Larsen J, Schønheyder HC, Singh KV, Lester CH, Olsen SS, Porsbo LJ, Garcia-Migura L, Jensen LB, Bisgaard M, Murray BE, Hammerum AM.

Emerg Infect Dis. 2011 Dec;17(12):2395-7. doi: 10.3201/eid1712.101584. No abstract available.


Nanoparticle-enhanced sensitivity of a nanogap-interdigitated electrode array impedimetric biosensor.

Singh KV, Bhura DK, Nandamuri G, Whited AM, Evans D, King J, Solanki R.

Langmuir. 2011 Nov 15;27(22):13931-9. doi: 10.1021/la202546a. Epub 2011 Oct 20.


Contribution of the enterococcal surface protein Esp to pathogenesis of Enterococcus faecium endocarditis.

Heikens E, Singh KV, Jacques-Palaz KD, van Luit-Asbroek M, Oostdijk EA, Bonten MJ, Murray BE, Willems RJ.

Microbes Infect. 2011 Dec;13(14-15):1185-90. doi: 10.1016/j.micinf.2011.08.006. Epub 2011 Aug 30.


Relative contributions of Ebp Pili and the collagen adhesin ace to host extracellular matrix protein adherence and experimental urinary tract infection by Enterococcus faecalis OG1RF.

Nallapareddy SR, Singh KV, Sillanpää J, Zhao M, Murray BE.

Infect Immun. 2011 Jul;79(7):2901-10. doi: 10.1128/IAI.00038-11. Epub 2011 Apr 19.


Conservation of Ebp-type pilus genes among Enterococci and demonstration of their role in adherence of Enterococcus faecalis to human platelets.

Nallapareddy SR, Sillanpää J, Mitchell J, Singh KV, Chowdhury SA, Weinstock GM, Sullam PM, Murray BE.

Infect Immun. 2011 Jul;79(7):2911-20. doi: 10.1128/IAI.00039-11. Epub 2011 Apr 18.


Importance of two Enterococcus faecium loci encoding Gls-like proteins for in vitro bile salts stress response and virulence.

Choudhury T, Singh KV, Sillanpää J, Nallapareddy SR, Murray BE.

J Infect Dis. 2011 Apr 15;203(8):1147-54. doi: 10.1093/infdis/jiq160.

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