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Items: 1 to 50 of 198

1.

An RNAi supplemented diet as a reverse genetics tool to control bluegreen aphid, a major pest of legumes.

Jacques S, Reidy-Crofts J, Sperschneider J, Kamphuis LG, Gao LL, Edwards OR, Singh KB.

Sci Rep. 2020 Jan 31;10(1):1604. doi: 10.1038/s41598-020-58442-4.

2.

RNA-seq reveals novel mechanistic targets of withaferin A in prostate cancer cellss.

Kim SH, Hahm ER, Singh KB, Shiva S, Stewart-Ornstein J, Singh SV.

Carcinogenesis. 2020 Jan 31. pii: bgaa009. doi: 10.1093/carcin/bgaa009. [Epub ahead of print]

PMID:
32002539
3.

A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer-Induced Osteolytic Bone Resorption.

Pore SK, Hahm ER, Kim SH, Singh KB, Nyiranshuti L, Latoche JD, Anderson CJ, Adamik J, Galson DL, Weiss KR, Watters RJ, Lee B, Kumta PN, Singh SV.

Mol Cancer Ther. 2020 Feb;19(2):420-431. doi: 10.1158/1535-7163.MCT-19-0611. Epub 2019 Nov 29.

PMID:
31784454
4.

A specific fungal transcription factor controls effector gene expression and orchestrates the establishment of the necrotrophic pathogen lifestyle on wheat.

Jones DAB, John E, Rybak K, Phan HTT, Singh KB, Lin SY, Solomon PS, Oliver RP, Tan KC.

Sci Rep. 2019 Nov 4;9(1):15884. doi: 10.1038/s41598-019-52444-7.

5.

A MYC2/MYC3/MYC4-dependent transcription factor network regulates water spray-responsive gene expression and jasmonate levels.

Van Moerkercke A, Duncan O, Zander M, Šimura J, Broda M, Vanden Bossche R, Lewsey MG, Lama S, Singh KB, Ljung K, Ecker JR, Goossens A, Millar AH, Van Aken O.

Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):23345-23356. doi: 10.1073/pnas.1911758116. Epub 2019 Oct 29.

PMID:
31662474
6.

Reversal of the Warburg phenomenon in chemoprevention of prostate cancer by sulforaphane.

Singh KB, Hahm ER, Alumkal JJ, Foley LM, Hitchens TK, Shiva SS, Parikh RA, Jacobs BL, Singh SV.

Carcinogenesis. 2019 Dec 31;40(12):1545-1556. doi: 10.1093/carcin/bgz155.

PMID:
31555797
7.

Leelamine Is a Novel Lipogenesis Inhibitor in Prostate Cancer Cells In Vitro and In Vivo.

Singh KB, Hahm ER, Pore SK, Singh SV.

Mol Cancer Ther. 2019 Oct;18(10):1800-1810. doi: 10.1158/1535-7163.MCT-19-0046. Epub 2019 Aug 8.

PMID:
31395683
8.

A quinoline alkaloid rich Quisqualis indica floral extract enhances the bioactivity.

Rout PK, Kumar P, Rao YR, Kumar A, Bawankule DU, Singh R, Singh KB, Chanotiya CS, Naik SN.

Nat Prod Res. 2019 Jul 2:1-7. doi: 10.1080/14786419.2019.1634709. [Epub ahead of print]

PMID:
31264476
9.

Additive and epistatic interactions between AKR and AIN loci conferring bluegreen aphid resistance and hypersensitivity in Medicago truncatula.

Kamphuis LG, Klingler JP, Jacques S, Gao LL, Edwards OR, Singh KB.

J Exp Bot. 2019 Sep 24;70(18):4887-4902. doi: 10.1093/jxb/erz222.

10.

Transcriptome analysis reveals molecular mechanisms of sclerotial development in the rice sheath blight pathogen Rhizoctonia solani AG1-IA.

Shu C, Zhao M, Anderson JP, Garg G, Singh KB, Zheng W, Wang C, Yang M, Zhou E.

Funct Integr Genomics. 2019 Sep;19(5):743-758. doi: 10.1007/s10142-019-00677-0. Epub 2019 May 3.

PMID:
31054140
11.

The role of jasmonate signalling in quinolizidine alkaloid biosynthesis, wounding and aphid predation response in narrow-leafed lupin.

Frick KM, Foley RC, Siddique KHM, Singh KB, Kamphuis LG.

Funct Plant Biol. 2019 Apr;46(5):443-454. doi: 10.1071/FP18278.

PMID:
30940332
12.

The Arabidopsis altered in stress response2 is Impaired in Resistance to Root and Leaf Necrotrophic Fungal Pathogens.

Thatcher LF, Singh KB.

Plants (Basel). 2019 Mar 11;8(3). pii: E60. doi: 10.3390/plants8030060.

13.

Identification and profiling of narrow-leafed lupin (Lupinus angustifolius) microRNAs during seed development.

DeBoer K, Melser S, Sperschneider J, Kamphuis LG, Garg G, Gao LL, Frick K, Singh KB.

BMC Genomics. 2019 Feb 14;20(1):135. doi: 10.1186/s12864-019-5521-8.

14.

Cytokine gene expression following RSV-A infection.

Khare VM, Saxena VK, Tomar A, Nyinawabera A, Singh KB, Ashby CR Jr, Tiwari AK.

Front Biosci (Landmark Ed). 2019 Jan 1;24:463-481.

PMID:
30468667
15.

Identification of putative flowering genes and transcription factors from flower de novo transcriptome dataset of tuberose (Polianthes tuberosa L.).

Madhavan J, Jayaswal P, Singh KBM, Rao U.

Data Brief. 2018 Sep 22;20:2027-2035. doi: 10.1016/j.dib.2018.09.051. eCollection 2018 Oct.

16.

The Arabidopsis RNA Polymerase II Carboxyl Terminal Domain (CTD) Phosphatase-Like1 (CPL1) is a biotic stress susceptibility gene.

Thatcher LF, Foley R, Casarotto HJ, Gao LL, Kamphuis LG, Melser S, Singh KB.

Sci Rep. 2018 Sep 7;8(1):13454. doi: 10.1038/s41598-018-31837-0.

17.

Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer.

Singh KB, Ji X, Singh SV.

Mol Cancer Ther. 2018 Oct;17(10):2079-2090. doi: 10.1158/1535-7163.MCT-18-0117. Epub 2018 Jul 20.

18.

MHC-B haplotypes impact susceptibility and resistance to RSV-A infection.

Khare VM, Saxena VK, Tomar A, Singh KP, Singh KB, Tiwari AK.

Front Biosci (Elite Ed). 2018 Jun 1;10:506-519.

PMID:
29772523
19.

INDEL variation in the regulatory region of the major flowering time gene LanFTc1 is associated with vernalization response and flowering time in narrow-leafed lupin (Lupinus angustifolius L.).

Taylor CM, Kamphuis LG, Zhang W, Garg G, Berger JD, Mousavi-Derazmahalleh M, Bayer PE, Edwards D, Singh KB, Cowling WA, Nelson MN.

Plant Cell Environ. 2019 Jan;42(1):174-187. doi: 10.1111/pce.13320. Epub 2018 May 23.

PMID:
29677403
20.

Prostate cancer chemoprevention by sulforaphane in a preclinical mouse model is associated with inhibition of fatty acid metabolism.

Singh KB, Kim SH, Hahm ER, Pore SK, Jacobs BL, Singh SV.

Carcinogenesis. 2018 May 28;39(6):826-837. doi: 10.1093/carcin/bgy051.

21.

Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0.

Sperschneider J, Dodds PN, Gardiner DM, Singh KB, Taylor JM.

Mol Plant Pathol. 2018 Sep;19(9):2094-2110. doi: 10.1111/mpp.12682. Epub 2018 May 11.

22.

Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate.

Singh KB, Hahm ER, Rigatti LH, Normolle DP, Yuan JM, Singh SV.

Cancer Prev Res (Phila). 2018 Jun;11(6):337-346. doi: 10.1158/1940-6207.CAPR-17-0389. Epub 2018 Mar 15.

23.

Characterization of the genetic factors affecting quinolizidine alkaloid biosynthesis and its response to abiotic stress in narrow-leafed lupin (Lupinus angustifolius L.).

Frick KM, Foley RC, Kamphuis LG, Siddique KHM, Garg G, Singh KB.

Plant Cell Environ. 2018 Sep;41(9):2155-2168. doi: 10.1111/pce.13172. Epub 2018 May 10.

PMID:
29473655
24.

Exploring the genetic and adaptive diversity of a pan-Mediterranean crop wild relative: narrow-leafed lupin.

Mousavi-Derazmahalleh M, Bayer PE, Nevado B, Hurgobin B, Filatov D, Kilian A, Kamphuis LG, Singh KB, Berger JD, Hane JK, Edwards D, Erskine W, Nelson MN.

Theor Appl Genet. 2018 Apr;131(4):887-901. doi: 10.1007/s00122-017-3045-7. Epub 2018 Jan 20.

25.

ApoplastP: prediction of effectors and plant proteins in the apoplast using machine learning.

Sperschneider J, Dodds PN, Singh KB, Taylor JM.

New Phytol. 2018 Mar;217(4):1764-1778. doi: 10.1111/nph.14946. Epub 2017 Dec 15.

26.

Characterization of narrow-leaf lupin (Lupinus angustifolius L.) recombinant major allergen IgE-binding proteins and the natural β-conglutin counterparts in sweet lupin seed species.

Jimenez-Lopez JC, Foley RC, Brear E, Clarke VC, Lima-Cabello E, Florido JF, Singh KB, Alché JD, Smith PMC.

Food Chem. 2018 Apr 1;244:60-70. doi: 10.1016/j.foodchem.2017.10.015. Epub 2017 Oct 6.

PMID:
29120805
27.

Comparative secretome analysis of Rhizoctonia solani isolates with different host ranges reveals unique secretomes and cell death inducing effectors.

Anderson JP, Sperschneider J, Win J, Kidd B, Yoshida K, Hane J, Saunders DGO, Singh KB.

Sci Rep. 2017 Sep 5;7(1):10410. doi: 10.1038/s41598-017-10405-y.

28.

Formononetin, a methoxy isoflavone, enhances bone regeneration in a mouse model of cortical bone defect.

Singh KB, Dixit M, Dev K, Maurya R, Singh D.

Br J Nutr. 2017 Jun;117(11):1511-1522. doi: 10.1017/S0007114517001556. Epub 2017 Jul 10.

PMID:
28689509
29.

The interactions of metal cations and oxyanions with protein tyrosine phosphatase 1B.

Singh KB, Maret W.

Biometals. 2017 Aug;30(4):517-527. doi: 10.1007/s10534-017-0019-9. Epub 2017 May 24.

30.

Ethylene Signaling Is Important for Isoflavonoid-Mediated Resistance to Rhizoctonia solani in Roots of Medicago truncatula.

Liu Y, Hassan S, Kidd BN, Garg G, Mathesius U, Singh KB, Anderson JP.

Mol Plant Microbe Interact. 2017 Sep;30(9):691-700. doi: 10.1094/MPMI-03-17-0057-R. Epub 2017 Jun 21.

31.

Functional block of IL-17 cytokine promotes bone healing by augmenting FOXO1 and ATF4 activity in cortical bone defect model.

Dixit M, Singh KB, Prakash R, Singh D.

Osteoporos Int. 2017 Jul;28(7):2207-2220. doi: 10.1007/s00198-017-4012-5. Epub 2017 Mar 24.

PMID:
28341898
32.

LOCALIZER: subcellular localization prediction of both plant and effector proteins in the plant cell.

Sperschneider J, Catanzariti AM, DeBoer K, Petre B, Gardiner DM, Singh KB, Dodds PN, Taylor JM.

Sci Rep. 2017 Mar 16;7:44598. doi: 10.1038/srep44598.

33.

Fatty Acid Synthesis Intermediates Represent Novel Noninvasive Biomarkers of Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate.

Singh KB, Singh SV.

Cancer Prev Res (Phila). 2017 May;10(5):279-289. doi: 10.1158/1940-6207.CAPR-17-0001. Epub 2017 Mar 14.

34.

Salicylic Acid-Dependent Plant Stress Signaling via Mitochondrial Succinate Dehydrogenase.

Belt K, Huang S, Thatcher LF, Casarotto H, Singh KB, Van Aken O, Millar AH.

Plant Physiol. 2017 Apr;173(4):2029-2040. doi: 10.1104/pp.16.00060. Epub 2017 Feb 16.

35.

Synthesis and biological evaluation of heterocyclic analogues of pregnenolone as novel anti-osteoporotic agents.

Maurya SW, Dev K, Singh KB, Rai R, Siddiqui IR, Singh D, Maurya R.

Bioorg Med Chem Lett. 2017 Mar 15;27(6):1390-1396. doi: 10.1016/j.bmcl.2017.02.004. Epub 2017 Feb 4.

PMID:
28202325
36.

Quinolizidine Alkaloid Biosynthesis in Lupins and Prospects for Grain Quality Improvement.

Frick KM, Kamphuis LG, Siddique KH, Singh KB, Foley RC.

Front Plant Sci. 2017 Jan 31;8:87. doi: 10.3389/fpls.2017.00087. eCollection 2017. Review.

37.

Disease Subtype-Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A.

Samanta SK, Sehrawat A, Kim SH, Hahm ER, Shuai Y, Roy R, Pore SK, Singh KB, Christner SM, Beumer JH, Davidson NE, Singh SV.

J Natl Cancer Inst. 2016 Dec 31;109(6). doi: 10.1093/jnci/djw293. Print 2017 Jun.

38.

Narrow-Leafed Lupin (Lupinus angustifolius) β1- and β6-Conglutin Proteins Exhibit Antifungal Activity, Protecting Plants against Necrotrophic Pathogen Induced Damage from Sclerotinia sclerotiorum and Phytophthora nicotianae.

Jimenez-Lopez JC, Melser S, DeBoer K, Thatcher LF, Kamphuis LG, Foley RC, Singh KB.

Front Plant Sci. 2016 Dec 9;7:1856. doi: 10.3389/fpls.2016.01856. eCollection 2016.

39.

Narrow-leafed lupin (Lupinus angustifolius L.) β-conglutin proteins modulate the insulin signaling pathway as potential type 2 diabetes treatment and inflammatory-related disease amelioration.

Lima-Cabello E, Alche V, Foley RC, Andrikopoulos S, Morahan G, Singh KB, Alche JD, Jimenez-Lopez JC.

Mol Nutr Food Res. 2017 May;61(5). doi: 10.1002/mnfr.201600819. Epub 2017 Feb 13.

40.

Mitochondrial dysfunction in cancer chemoprevention by phytochemicals from dietary and medicinal plants.

Sehrawat A, Roy R, Pore SK, Hahm ER, Samanta SK, Singh KB, Kim SH, Singh K, Singh SV.

Semin Cancer Biol. 2017 Dec;47:147-153. doi: 10.1016/j.semcancer.2016.11.009. Epub 2016 Nov 17. Review.

42.

A comprehensive draft genome sequence for lupin (Lupinus angustifolius), an emerging health food: insights into plant-microbe interactions and legume evolution.

Hane JK, Ming Y, Kamphuis LG, Nelson MN, Garg G, Atkins CA, Bayer PE, Bravo A, Bringans S, Cannon S, Edwards D, Foley R, Gao LL, Harrison MJ, Huang W, Hurgobin B, Li S, Liu CW, McGrath A, Morahan G, Murray J, Weller J, Jian J, Singh KB.

Plant Biotechnol J. 2017 Mar;15(3):318-330. doi: 10.1111/pbi.12615. Epub 2016 Sep 23.

43.

Genetic Mapping of a Major Resistance Gene to Pea Aphid (Acyrthosipon pisum) in the Model Legume Medicago truncatula.

Kamphuis LG, Guo SM, Gao LL, Singh KB.

Int J Mol Sci. 2016 Jul 29;17(8). pii: E1224. doi: 10.3390/ijms17081224.

44.

c-Myc is a novel target of cell cycle arrest by honokiol in prostate cancer cells.

Hahm ER, Singh KB, Singh SV.

Cell Cycle. 2016 Sep;15(17):2309-20. doi: 10.1080/15384101.2016.1201253. Epub 2016 Jun 24.

45.

Mass-spectrometry data for Rhizoctonia solani proteins produced during infection of wheat and vegetative growth.

Anderson JP, Hane JK, Stoll T, Pain N, Hastie ML, Kaur P, Hoogland C, Gorman JJ, Singh KB.

Data Brief. 2016 May 27;8:267-71. doi: 10.1016/j.dib.2016.05.042. eCollection 2016 Sep.

46.

Jasmonate Signalling and Defence Responses in the Model Legume Medicago truncatula-A Focus on Responses to Fusarium Wilt Disease.

Thatcher LF, Gao LL, Singh KB.

Plants (Basel). 2016 Feb 5;5(1). pii: E11. doi: 10.3390/plants5010011.

47.

Reactive Oxygen Species Play a Role in the Infection of the Necrotrophic Fungi, Rhizoctonia solani in Wheat.

Foley RC, Kidd BN, Hane JK, Anderson JP, Singh KB.

PLoS One. 2016 Mar 31;11(3):e0152548. doi: 10.1371/journal.pone.0152548. eCollection 2016.

48.

Sulforaphane Inhibits c-Myc-Mediated Prostate Cancer Stem-Like Traits.

Vyas AR, Moura MB, Hahm ER, Singh KB, Singh SV.

J Cell Biochem. 2016 Nov;117(11):2482-95. doi: 10.1002/jcb.25541. Epub 2016 May 26.

49.

Comparative genomics and prediction of conditionally dispensable sequences in legume-infecting Fusarium oxysporum formae speciales facilitates identification of candidate effectors.

Williams AH, Sharma M, Thatcher LF, Azam S, Hane JK, Sperschneider J, Kidd BN, Anderson JP, Ghosh R, Garg G, Lichtenzveig J, Kistler HC, Shea T, Young S, Buck SA, Kamphuis LG, Saxena R, Pande S, Ma LJ, Varshney RK, Singh KB.

BMC Genomics. 2016 Mar 5;17:191. doi: 10.1186/s12864-016-2486-8.

50.

Proteomic Analysis of Rhizoctonia solani Identifies Infection-specific, Redox Associated Proteins and Insight into Adaptation to Different Plant Hosts.

Anderson JP, Hane JK, Stoll T, Pain N, Hastie ML, Kaur P, Hoogland C, Gorman JJ, Singh KB.

Mol Cell Proteomics. 2016 Apr;15(4):1188-203. doi: 10.1074/mcp.M115.054502. Epub 2016 Jan 25.

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