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Items: 1 to 50 of 167

1.

Differential Effects of Novel Dopamine Reuptake Inhibitors on Interference With Long-Term Social Memory in Mice.

Camats-Perna J, Kalaba P, Ebner K, Sartori SB, Vuyyuru H, Aher NY, Dragačević V, Singewald N, Engelmann M, Lubec G.

Front Behav Neurosci. 2019 Apr 11;13:63. doi: 10.3389/fnbeh.2019.00063. eCollection 2019.

2.

Role for Chromatin Remodeling Factor Chd1 in Learning and Memory.

Schoberleitner I, Mutti A, Sah A, Wille A, Gimeno-Valiente F, Piatti P, Kharitonova M, Torres L, López-Rodas G, Liu JJ, Singewald N, Schwarzer C, Lusser A.

Front Mol Neurosci. 2019 Jan 23;12:3. doi: 10.3389/fnmol.2019.00003. eCollection 2019.

3.

Epigenetic Mechanisms Within the Cingulate Cortex Regulate Innate Anxiety-Like Behavior.

Sah A, Sotnikov S, Kharitonova M, Schmuckermair C, Diepold RP, Landgraf R, Whittle N, Singewald N.

Int J Neuropsychopharmacol. 2019 Apr 1;22(4):317-328. doi: 10.1093/ijnp/pyz004.

4.

Rodent models of impaired fear extinction.

Singewald N, Holmes A.

Psychopharmacology (Berl). 2019 Jan;236(1):21-32. doi: 10.1007/s00213-018-5054-x. Epub 2018 Oct 31. Review.

5.

Increased amygdalar metabotropic glutamate receptor 7 mRNA in a genetic mouse model of impaired fear extinction.

O'Connor RM, McCafferty CP, Bravo JA, Singewald N, Holmes A, Cryan JF.

Psychopharmacology (Berl). 2019 Jan;236(1):265-272. doi: 10.1007/s00213-018-5031-4. Epub 2018 Sep 13.

PMID:
30215216
6.

Potential of microRNAs as novel targets in the alleviation of pathological fear.

Murphy CP, Singewald N.

Genes Brain Behav. 2018 Mar;17(3):e12427. doi: 10.1111/gbb.12427. Epub 2017 Nov 24. Review.

PMID:
29028150
7.

MicroRNA-Mediated Rescue of Fear Extinction Memory by miR-144-3p in Extinction-Impaired Mice.

Murphy CP, Li X, Maurer V, Oberhauser M, Gstir R, Wearick-Silva LE, Viola TW, Schafferer S, Grassi-Oliveira R, Whittle N, Hüttenhofer A, Bredy TW, Singewald N.

Biol Psychiatry. 2017 Jun 15;81(12):979-989. doi: 10.1016/j.biopsych.2016.12.021. Epub 2016 Dec 26.

8.

Enhancing dopaminergic signaling and histone acetylation promotes long-term rescue of deficient fear extinction.

Whittle N, Maurer V, Murphy C, Rainer J, Bindreither D, Hauschild M, Scharinger A, Oberhauser M, Keil T, Brehm C, Valovka T, Striessnig J, Singewald N.

Transl Psychiatry. 2016 Dec 6;6(12):e974. doi: 10.1038/tp.2016.231.

9.

Satb2 determines miRNA expression and long-term memory in the adult central nervous system.

Jaitner C, Reddy C, Abentung A, Whittle N, Rieder D, Delekate A, Korte M, Jain G, Fischer A, Sananbenesi F, Cera I, Singewald N, Dechant G, Apostolova G.

Elife. 2016 Nov 29;5. pii: e17361. doi: 10.7554/eLife.17361.

10.

Increased cocaine-induced conditioned place preference during periadolescence in maternally separated male BALB/c mice: the role of cortical BDNF, microRNA-212, and MeCP2.

Viola TW, Wearick-Silva LE, De Azeredo LA, Centeno-Silva A, Murphy C, Marshall P, Li X, Singewald N, Garcia F, Bredy TW, Grassi-Oliveira R.

Psychopharmacology (Berl). 2016 Sep;233(17):3279-88. doi: 10.1007/s00213-016-4373-z. Epub 2016 Jul 9.

PMID:
27392631
11.

Reduced Anxiety-Like Behavior and Altered Hippocampal Morphology in Female p75NTR(exon IV-/-) Mice.

Puschban Z, Sah A, Grutsch I, Singewald N, Dechant G.

Front Behav Neurosci. 2016 Jun 1;10:103. doi: 10.3389/fnbeh.2016.00103. eCollection 2016.

12.

Dysregulation of select ATP-dependent chromatin remodeling factors in high trait anxiety.

Wille A, Amort T, Singewald N, Sartori SB, Lusser A.

Behav Brain Res. 2016 Sep 15;311:141-146. doi: 10.1016/j.bbr.2016.05.036. Epub 2016 May 18.

13.

Depletion of nucleus accumbens dopamine leads to impaired reward and aversion processing in mice: Relevance to motivation pathologies.

Bergamini G, Sigrist H, Ferger B, Singewald N, Seifritz E, Pryce CR.

Neuropharmacology. 2016 Oct;109:306-319. doi: 10.1016/j.neuropharm.2016.03.048. Epub 2016 Mar 30.

14.

Fluoxetine normalizes disrupted light-induced entrainment, fragmented ultradian rhythms and altered hippocampal clock gene expression in an animal model of high trait anxiety- and depression-related behavior.

Schaufler J, Ronovsky M, Savalli G, Cabatic M, Sartori SB, Singewald N, Pollak DD.

Ann Med. 2016;48(1-2):17-27. doi: 10.3109/07853890.2015.1122216. Epub 2015 Dec 18.

15.

Impaired Contextual Fear Extinction Learning is Associated with Aberrant Regulation of CHD-Type Chromatin Remodeling Factors.

Wille A, Maurer V, Piatti P, Whittle N, Rieder D, Singewald N, Lusser A.

Front Behav Neurosci. 2015 Nov 18;9:313. doi: 10.3389/fnbeh.2015.00313. eCollection 2015.

16.

Combined Neuropeptide S and D-Cycloserine Augmentation Prevents the Return of Fear in Extinction-Impaired Rodents: Advantage of Dual versus Single Drug Approaches.

Sartori SB, Maurer V, Murphy C, Schmuckermair C, Muigg P, Neumann ID, Whittle N, Singewald N.

Int J Neuropsychopharmacol. 2016 Jun 1;19(6). pii: pyv128. doi: 10.1093/ijnp/pyv128. Print 2016 Jun.

17.

Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.

Marschallinger J, Schäffner I, Klein B, Gelfert R, Rivera FJ, Illes S, Grassner L, Janssen M, Rotheneichner P, Schmuckermair C, Coras R, Boccazzi M, Chishty M, Lagler FB, Renic M, Bauer HC, Singewald N, Blümcke I, Bogdahn U, Couillard-Despres S, Lie DC, Abbracchio MP, Aigner L.

Nat Commun. 2015 Oct 27;6:8466. doi: 10.1038/ncomms9466.

18.

Prefrontal inputs to the amygdala instruct fear extinction memory formation.

Bukalo O, Pinard CR, Silverstein S, Brehm C, Hartley ND, Whittle N, Colacicco G, Busch E, Patel S, Singewald N, Holmes A.

Sci Adv. 2015 Jul;1(6). pii: e1500251. Epub 2015 Jul 31.

19.

Exploring the role of neuropeptide S in the regulation of arousal: a functional anatomical study.

Adori C, Barde S, Vas S, Ebner K, Su J, Svensson C, Mathé AA, Singewald N, Reinscheid RR, Uhlén M, Kultima K, Bagdy G, Hökfelt T.

Brain Struct Funct. 2016 Sep;221(7):3521-46. doi: 10.1007/s00429-015-1117-5. Epub 2015 Oct 13.

PMID:
26462664
20.

The L-type calcium channel Cav1.3 is required for proper hippocampal neurogenesis and cognitive functions.

Marschallinger J, Sah A, Schmuckermair C, Unger M, Rotheneichner P, Kharitonova M, Waclawiczek A, Gerner P, Jaksch-Bogensperger H, Berger S, Striessnig J, Singewald N, Couillard-Despres S, Aigner L.

Cell Calcium. 2015 Dec;58(6):606-16. doi: 10.1016/j.ceca.2015.09.007. Epub 2015 Oct 3.

PMID:
26459417
21.

Cell-type-specific tuning of Cav1.3 Ca(2+)-channels by a C-terminal automodulatory domain.

Scharinger A, Eckrich S, Vandael DH, Schönig K, Koschak A, Hecker D, Kaur G, Lee A, Sah A, Bartsch D, Benedetti B, Lieb A, Schick B, Singewald N, Sinnegger-Brauns MJ, Carbone E, Engel J, Striessnig J.

Front Cell Neurosci. 2015 Aug 24;9:309. doi: 10.3389/fncel.2015.00309. eCollection 2015.

22.

Substance P excites GABAergic neurons in the mouse central amygdala through neurokinin 1 receptor activation.

Sosulina L, Strippel C, Romo-Parra H, Walter AL, Kanyshkova T, Sartori SB, Lange MD, Singewald N, Pape HC.

J Neurophysiol. 2015 Oct;114(4):2500-8. doi: 10.1152/jn.00883.2014. Epub 2015 Sep 2.

23.

Durable fear memories require PSD-95.

Fitzgerald PJ, Pinard CR, Camp MC, Feyder M, Sah A, Bergstrom HC, Graybeal C, Liu Y, Schlüter OM, Grant SG, Singewald N, Xu W, Holmes A.

Mol Psychiatry. 2015 Jul;20(7):913. doi: 10.1038/mp.2015.44. Epub 2015 Mar 31. No abstract available.

PMID:
25824301
24.

Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide S receptor activity.

Slattery DA, Naik RR, Grund T, Yen YC, Sartori SB, Füchsl A, Finger BC, Elfving B, Nordemann U, Guerrini R, Calo G, Wegener G, Mathé AA, Singewald N, Czibere L, Landgraf R, Neumann ID.

J Neurosci. 2015 Mar 18;35(11):4599-613. doi: 10.1523/JNEUROSCI.4764-13.2015.

25.

Increased conditioned place preference for cocaine in high anxiety related behavior (HAB) mice is associated with an increased activation in the accumbens corridor.

Prast JM, Schardl A, Sartori SB, Singewald N, Saria A, Zernig G.

Front Behav Neurosci. 2014 Dec 22;8:441. doi: 10.3389/fnbeh.2014.00441. eCollection 2014.

26.

Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders.

Singewald N, Schmuckermair C, Whittle N, Holmes A, Ressler KJ.

Pharmacol Ther. 2015 May;149:150-90. doi: 10.1016/j.pharmthera.2014.12.004. Epub 2014 Dec 27. Review.

27.

Durable fear memories require PSD-95.

Fitzgerald PJ, Pinard CR, Camp MC, Feyder M, Sah A, Bergstrom HC, Graybeal C, Liu Y, Schlüter OM, Grant SG, Singewald N, Xu W, Holmes A.

Mol Psychiatry. 2015 Jul;20(7):901-12. doi: 10.1038/mp.2014.161. Epub 2014 Dec 16. Erratum in: Mol Psychiatry. 2015 Jul;20(7):913.

28.

GPR39 Zn(2+)-sensing receptor: a new target in antidepressant development?

Młyniec K, Singewald N, Holst B, Nowak G.

J Affect Disord. 2015 Mar 15;174:89-100. doi: 10.1016/j.jad.2014.11.033. Epub 2014 Nov 26. Review.

PMID:
25490458
29.

Erratum to: Dietary magnesium restriction reduces amygdala-hypothalamic GluN1 receptor complex levels in mice.

Ghafari M, Whittle N, Miklósi AG, Kotlowski C, Schmuckermair C, Berger J, Bennett KL, Singewald N, Lubec G.

Brain Struct Funct. 2015 Jul;220(4):2223. doi: 10.1007/s00429-014-0820-y. No abstract available.

PMID:
24965486
30.

Loss of Nogo receptor homolog NgR2 alters spine morphology of CA1 neurons and emotionality in adult mice.

Borrie SC, Sartori SB, Lehmann J, Sah A, Singewald N, Bandtlow CE.

Front Behav Neurosci. 2014 May 15;8:175. doi: 10.3389/fnbeh.2014.00175. eCollection 2014.

31.

Pharmacophore modeling, virtual screening, and in vitro testing reveal haloperidol, eprazinone, and fenbutrazate as neurokinin receptors ligands.

Krautscheid Y, Senning CJ, Sartori SB, Singewald N, Schuster D, Stuppner H.

J Chem Inf Model. 2014 Jun 23;54(6):1747-57. doi: 10.1021/ci500106z. Epub 2014 Jun 12.

PMID:
24849814
32.

Dietary magnesium restriction reduces amygdala-hypothalamic GluN1 receptor complex levels in mice.

Ghafari M, Whittle N, Miklósi AG, Kotlowski C, Schmuckermair C, Berger J, Bennett KL, Singewald N, Lubec G.

Brain Struct Funct. 2015 Jul;220(4):2209-21. doi: 10.1007/s00429-014-0779-8. Epub 2014 May 8. Erratum in: Brain Struct Funct. 2015 Jul;220(4):2223. Kotlowsky, Caroline [Corrected to Kotlowski, Caroline].

PMID:
24807818
33.

HDAC inhibitors as cognitive enhancers in fear, anxiety and trauma therapy: where do we stand?

Whittle N, Singewald N.

Biochem Soc Trans. 2014 Apr;42(2):569-81. doi: 10.1042/BST20130233. Review.

34.

Bidirectional rescue of extreme genetic predispositions to anxiety: impact of CRH receptor 1 as epigenetic plasticity gene in the amygdala.

Sotnikov SV, Markt PO, Malik V, Chekmareva NY, Naik RR, Sah A, Singewald N, Holsboer F, Czibere L, Landgraf R.

Transl Psychiatry. 2014 Feb 11;4:e359. doi: 10.1038/tp.2013.127.

35.

Circadian abnormalities in a mouse model of high trait anxiety and depression.

Griesauer I, Diao W, Ronovsky M, Elbau I, Sartori S, Singewald N, Pollak DD.

Ann Med. 2014 May;46(3):148-54. doi: 10.3109/07853890.2013.866440. Epub 2014 Jan 10.

36.

Prefrontal single-unit firing associated with deficient extinction in mice.

Fitzgerald PJ, Whittle N, Flynn SM, Graybeal C, Pinard CR, Gunduz-Cinar O, Kravitz AV, Singewald N, Holmes A.

Neurobiol Learn Mem. 2014 Sep;113:69-81. doi: 10.1016/j.nlm.2013.11.002. Epub 2013 Nov 11.

37.

Temporal factors in the extinction of fear in inbred mouse strains differing in extinction efficacy.

MacPherson K, Whittle N, Camp M, Gunduz-Cinar O, Singewald N, Holmes A.

Biol Mood Anxiety Disord. 2013 Jul 5;3(1):13. doi: 10.1186/2045-5380-3-13.

38.

Single dose of L-dopa makes extinction memories context-independent and prevents the return of fear.

Haaker J, Gaburro S, Sah A, Gartmann N, Lonsdorf TB, Meier K, Singewald N, Pape HC, Morellini F, Kalisch R.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):E2428-36. doi: 10.1073/pnas.1303061110. Epub 2013 Jun 10.

39.

Oligodendroglial alpha-synucleinopathy and MSA-like cardiovascular autonomic failure: experimental evidence.

Kuzdas D, Stemberger S, Gaburro S, Stefanova N, Singewald N, Wenning GK.

Exp Neurol. 2013 Sep;247:531-6. doi: 10.1016/j.expneurol.2013.02.002. Epub 2013 Feb 8.

40.

Behavioral and neurobiological effects of deep brain stimulation in a mouse model of high anxiety- and depression-like behavior.

Schmuckermair C, Gaburro S, Sah A, Landgraf R, Sartori SB, Singewald N.

Neuropsychopharmacology. 2013 Jun;38(7):1234-44. doi: 10.1038/npp.2013.21. Epub 2013 Jan 16.

41.

Individual differences in recovery from traumatic fear.

Holmes A, Singewald N.

Trends Neurosci. 2013 Jan;36(1):23-31. doi: 10.1016/j.tins.2012.11.003. Epub 2012 Dec 19. Review.

42.

Anxiety- rather than depression-like behavior is associated with adult neurogenesis in a female mouse model of higher trait anxiety- and comorbid depression-like behavior.

Sah A, Schmuckermair C, Sartori SB, Gaburro S, Kandasamy M, Irschick R, Klimaschewski L, Landgraf R, Aigner L, Singewald N.

Transl Psychiatry. 2012 Oct 16;2:e171. doi: 10.1038/tp.2012.94.

43.

Aldosterone increases earlier than corticosterone in new animal models of depression: is this an early marker?

Franklin M, Bermudez I, Hlavacova N, Babic S, Murck H, Schmuckermair C, Singewald N, Gaburro S, Jezova D.

J Psychiatr Res. 2012 Nov;46(11):1394-7. doi: 10.1016/j.jpsychires.2012.07.010. Epub 2012 Aug 14. Review. No abstract available.

PMID:
22901774
44.
45.

Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model.

Whittle N, Schmuckermair C, Gunduz Cinar O, Hauschild M, Ferraguti F, Holmes A, Singewald N.

Neuropharmacology. 2013 Jan;64:414-23. doi: 10.1016/j.neuropharm.2012.06.001. Epub 2012 Jun 18.

46.

Neural substrates for the distinct effects of presynaptic group III metabotropic glutamate receptors on extinction of contextual fear conditioning in mice.

Dobi A, Sartori SB, Busti D, Van der Putten H, Singewald N, Shigemoto R, Ferraguti F.

Neuropharmacology. 2013 Mar;66:274-89. doi: 10.1016/j.neuropharm.2012.05.025. Epub 2012 May 27.

47.

Increased levels of conditioned fear and avoidance behavior coincide with changes in phosphorylation of the protein kinase B (AKT) within the amygdala in a mouse model of extremes in trait anxiety.

Yen YC, Mauch CP, Dahlhoff M, Micale V, Bunck M, Sartori SB, Singewald N, Landgraf R, Wotjak CT.

Neurobiol Learn Mem. 2012 Jul;98(1):56-65. doi: 10.1016/j.nlm.2012.04.009. Epub 2012 May 9.

PMID:
22579802
48.

Genetic strain differences in learned fear inhibition associated with variation in neuroendocrine, autonomic, and amygdala dendritic phenotypes.

Camp MC, Macpherson KP, Lederle L, Graybeal C, Gaburro S, Debrouse LM, Ihne JL, Bravo JA, O'Connor RM, Ciocchi S, Wellman CL, Lüthi A, Cryan JF, Singewald N, Holmes A.

Neuropsychopharmacology. 2012 May;37(6):1534-47. doi: 10.1038/npp.2011.340. Epub 2012 Feb 15.

49.

Sub-chronic dietary tryptophan depletion--an animal model of depression with improved face and good construct validity.

Franklin M, Bermudez I, Murck H, Singewald N, Gaburro S.

J Psychiatr Res. 2012 Feb;46(2):239-47. doi: 10.1016/j.jpsychires.2011.10.003. Epub 2011 Nov 8.

PMID:
22074993
50.

The clinical implications of mouse models of enhanced anxiety.

Sartori SB, Landgraf R, Singewald N.

Future Neurol. 2011 Jul 1;6(4):531-571.

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