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Items: 1 to 50 of 314

1.

Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons.

Klein ME, Younts TJ, Cobo CF, Buxbaum AR, Aow J, Erdjument-Bromage H, Richard S, Malinow R, Neubert TA, Singer RH, Castillo PE, Jordan BA.

Cell Rep. 2019 Nov 12;29(7):1789-1799.e6. doi: 10.1016/j.celrep.2019.10.030.

2.

Rational Design of Fluorogenic and Spontaneously Blinking Labels for Super-Resolution Imaging.

Zheng Q, Ayala AX, Chung I, Weigel AV, Ranjan A, Falco N, Grimm JB, Tkachuk AN, Wu C, Lippincott-Schwartz J, Singer RH, Lavis LD.

ACS Cent Sci. 2019 Sep 25;5(9):1602-1613. doi: 10.1021/acscentsci.9b00676. Epub 2019 Sep 5.

3.

The structural basis for RNA selectivity by the IMP family of RNA-binding proteins.

Biswas J, Patel VL, Bhaskar V, Chao JA, Singer RH, Eliscovich C.

Nat Commun. 2019 Sep 30;10(1):4440. doi: 10.1038/s41467-019-12193-7.

4.

Mamo decodes hierarchical temporal gradients into terminal neuronal fate.

Liu LY, Long X, Yang CP, Miyares RL, Sugino K, Singer RH, Lee T.

Elife. 2019 Sep 23;8. pii: e48056. doi: 10.7554/eLife.48056.

5.

Imaging Single mRNA Molecules in Mammalian Cells Using an Optimized MS2-MCP System.

Vera M, Tutucci E, Singer RH.

Methods Mol Biol. 2019;2038:3-20. doi: 10.1007/978-1-4939-9674-2_1.

PMID:
31407274
6.

Retargeting of macroH2A following mitosis to cytogenetic-scale heterochromatic domains.

Sato H, Wu B, Delahaye F, Singer RH, Greally JM.

J Cell Biol. 2019 Jun 3;218(6):1810-1823. doi: 10.1083/jcb.201811109. Epub 2019 May 20.

PMID:
31110057
7.

Neurotransmitter identity is acquired in a lineage-restricted manner in the Drosophila CNS.

Lacin H, Chen HM, Long X, Singer RH, Lee T, Truman JW.

Elife. 2019 Mar 26;8. pii: e43701. doi: 10.7554/eLife.43701.

8.

Dentists' willingness to screen for cardiovascular disease in the dental care setting: Findings from a nationally representative survey.

Singer RH, Feaster DJ, Stoutenberg M, Hlaing WM, Pereyra M, Abel S, Pollack H, Gellman MD, Schneiderman N, Metsch LR.

Community Dent Oral Epidemiol. 2019 Aug;47(4):299-308. doi: 10.1111/cdoe.12457. Epub 2019 Mar 25.

PMID:
30908721
9.

The travels of mRNAs in neurons: do they know where they are going?

Das S, Singer RH, Yoon YJ.

Curr Opin Neurobiol. 2019 Aug;57:110-116. doi: 10.1016/j.conb.2019.01.016. Epub 2019 Feb 19. Review.

10.

Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers.

Limi S, Zhao Y, Guo P, Lopez-Jones M, Zheng D, Singer RH, Skoultchi AI, Cvekl A.

Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):234-244. doi: 10.1167/iovs.18-25921.

11.

Mapping Neurotransmitter Identity in the Whole-Mount Drosophila Brain Using Multiplex High-Throughput Fluorescence in Situ Hybridization.

Meissner GW, Nern A, Singer RH, Wong AM, Malkesman O, Long X.

Genetics. 2019 Feb;211(2):473-482. doi: 10.1534/genetics.118.301749. Epub 2018 Dec 18.

12.

The association of employment status with ideal cardiovascular health factors and behaviors among Hispanic/Latino adults: Findings from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Estrella ML, Rosenberg NI, Durazo-Arvizu RA, Gonzalez HM, Loop MS, Singer RH, Lash JP, Castañeda SF, Perreira KM, Eldeirawi K, Daviglus ML.

PLoS One. 2018 Nov 27;13(11):e0207652. doi: 10.1371/journal.pone.0207652. eCollection 2018.

13.

Single-mRNA detection in living S. cerevisiae using a re-engineered MS2 system.

Tutucci E, Vera M, Singer RH.

Nat Protoc. 2018 Oct;13(10):2268-2296. doi: 10.1038/s41596-018-0037-2.

PMID:
30218101
14.

Fluorescence Imaging Methods to Investigate Translation in Single Cells.

Biswas J, Liu Y, Singer RH, Wu B.

Cold Spring Harb Perspect Biol. 2019 Apr 1;11(4). pii: a032722. doi: 10.1101/cshperspect.a032722. Review.

15.

Imaging cell-type-specific dynamics of mRNAs in living mouse brain.

Nwokafor C, Singer RH, Lim H.

Methods. 2019 Mar 15;157:100-105. doi: 10.1016/j.ymeth.2018.07.009. Epub 2018 Jul 29.

PMID:
30067943
16.

Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process.

Limi S, Senecal A, Coleman R, Lopez-Jones M, Guo P, Polumbo C, Singer RH, Skoultchi AI, Cvekl A.

J Biol Chem. 2018 Aug 24;293(34):13176-13190. doi: 10.1074/jbc.RA118.001927. Epub 2018 Jun 29.

17.

A transgenic mouse for imaging activity-dependent dynamics of endogenous Arc mRNA in live neurons.

Das S, Moon HC, Singer RH, Park HY.

Sci Adv. 2018 Jun 20;4(6):eaar3448. doi: 10.1126/sciadv.aar3448. eCollection 2018 Jun.

18.

Better-quality diet is associated with lower odds of severe periodontitis in US Hispanics/Latinos.

Salazar CR, Laniado N, Mossavar-Rahmani Y, Borrell LN, Qi Q, Sotres-Alvarez D, Morse DE, Singer RH, Kaplan RC, Badner V, Lamster IB.

J Clin Periodontol. 2018 Jul;45(7):780-790. doi: 10.1111/jcpe.12926. Epub 2018 Jun 11.

19.

Transvection Goes Live-Visualizing Enhancer-Promoter Communication between Chromosomes.

Tsai A, Singer RH, Crocker J.

Mol Cell. 2018 Apr 19;70(2):195-196. doi: 10.1016/j.molcel.2018.04.004.

20.

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia.

Carvajal LA, Neriah DB, Senecal A, Benard L, Thiruthuvanathan V, Yatsenko T, Narayanagari SR, Wheat JC, Todorova TI, Mitchell K, Kenworthy C, Guerlavais V, Annis DA, Bartholdy B, Will B, Anampa JD, Mantzaris I, Aivado M, Singer RH, Coleman RA, Verma A, Steidl U.

Sci Transl Med. 2018 Apr 11;10(436). pii: eaao3003. doi: 10.1126/scitranslmed.aao3003.

21.

The association of periodontal disease and cardiovascular disease risk: Results from the Hispanic Community Health Study/Study of Latinos.

Singer RH, Stoutenberg M, Feaster DJ, Cai J, Hlaing WM, Metsch LR, Salazar CR, Beaver SM, Finlayson TL, Talavera G, Gellman MD, Schneiderman N.

J Periodontol. 2018 Jul;89(7):840-857. doi: 10.1002/JPER.17-0549. Epub 2018 Jul 20.

22.

Imaging mRNA In Vivo, from Birth to Death.

Tutucci E, Livingston NM, Singer RH, Wu B.

Annu Rev Biophys. 2018 May 20;47:85-106. doi: 10.1146/annurev-biophys-070317-033037. Epub 2018 Jan 18. Review.

PMID:
29345990
23.

Unfair Treatment and Periodontitis Among Adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Finlayson TL, Lemus H, Becerra K, Kaste LM, Beaver SM, Salazar CR, Singer RH, Youngblood ME Jr.

J Racial Ethn Health Disparities. 2018 Oct;5(5):1093-1106. doi: 10.1007/s40615-017-0459-5. Epub 2018 Jan 11.

24.

An improved MS2 system for accurate reporting of the mRNA life cycle.

Tutucci E, Vera M, Biswas J, Garcia J, Parker R, Singer RH.

Nat Methods. 2018 Jan;15(1):81-89. doi: 10.1038/nmeth.4502. Epub 2017 Nov 13.

25.

Occupational Exposures and Metabolic Syndrome Among Hispanics/Latinos: Cross-Sectional Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Bulka CM, Daviglus ML, Persky VW, Durazo-Arvizu RA, Avilés-Santa ML, Gallo LC, Hosgood HD 3rd, Singer RH, Talavera GA, Thyagarajan B, Zeng D, Argos M.

J Occup Environ Med. 2017 Nov;59(11):1047-1055. doi: 10.1097/JOM.0000000000001115.

26.

Nuclear microenvironments modulate transcription from low-affinity enhancers.

Tsai A, Muthusamy AK, Alves MR, Lavis LD, Singer RH, Stern DL, Crocker J.

Elife. 2017 Nov 2;6. pii: e28975. doi: 10.7554/eLife.28975.

27.

Intercellular mRNA trafficking via membrane nanotube-like extensions in mammalian cells.

Haimovich G, Ecker CM, Dunagin MC, Eggan E, Raj A, Gerst JE, Singer RH.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9873-E9882. doi: 10.1073/pnas.1706365114. Epub 2017 Oct 24.

28.

Localization of TFPI-2 in the nucleus modulates MMP-2 gene expression in breast cancer cells.

Wang G, Zeng Y, Chen S, Li D, Li W, Zhou Y, Singer RH, Gu W.

Sci Rep. 2017 Oct 19;7(1):13575. doi: 10.1038/s41598-017-14148-8.

29.

Quantitative mRNA imaging throughout the entire Drosophila brain.

Long X, Colonell J, Wong AM, Singer RH, Lionnet T.

Nat Methods. 2017 Jul;14(7):703-706. doi: 10.1038/nmeth.4309. Epub 2017 Jun 5.

PMID:
28581495
30.

Binding of DEAD-box helicase Dhh1 to the 5'-untranslated region of ASH1 mRNA represses localized translation of ASH1 in yeast cells.

Zhang Q, Meng X, Li D, Chen S, Luo J, Zhu L, Singer RH, Gu W.

J Biol Chem. 2017 Jun 9;292(23):9787-9800. doi: 10.1074/jbc.M117.776492. Epub 2017 Apr 27.

31.

RNP transport in cell biology: the long and winding road.

Eliscovich C, Singer RH.

Curr Opin Cell Biol. 2017 Apr;45:38-46. doi: 10.1016/j.ceb.2017.02.008. Epub 2017 Mar 1. Review.

32.

Imaging mRNA and protein interactions within neurons.

Eliscovich C, Shenoy SM, Singer RH.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1875-E1884. doi: 10.1073/pnas.1621440114. Epub 2017 Feb 21.

33.

Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation.

Pignatelli J, Bravo-Cordero JJ, Roh-Johnson M, Gandhi SJ, Wang Y, Chen X, Eddy RJ, Xue A, Singer RH, Hodgson L, Oktay MH, Condeelis JS.

Sci Rep. 2016 Nov 30;6:37874. doi: 10.1038/srep37874.

34.

Single-Cell and Single-Molecule Analysis of Gene Expression Regulation.

Vera M, Biswas J, Senecal A, Singer RH, Park HY.

Annu Rev Genet. 2016 Nov 23;50:267-291. Review.

35.

Glutamate-induced RNA localization and translation in neurons.

Yoon YJ, Wu B, Buxbaum AR, Das S, Tsai A, English BP, Grimm JB, Lavis LD, Singer RH.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6877-E6886. Epub 2016 Oct 17.

36.

IMP1, an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model.

Nwokafor CU, Sellers RS, Singer RH.

Oncotarget. 2016 Nov 8;7(45):72662-72671. doi: 10.18632/oncotarget.12083.

37.

Chronic Periodontitis Genome-wide Association Study in the Hispanic Community Health Study / Study of Latinos.

Sanders AE, Sofer T, Wong Q, Kerr KF, Agler C, Shaffer JR, Beck JD, Offenbacher S, Salazar CR, North KE, Marazita ML, Laurie CC, Singer RH, Cai J, Finlayson TL, Divaris K.

J Dent Res. 2017 Jan;96(1):64-72. doi: 10.1177/0022034516664509. Epub 2016 Oct 1.

38.

Subnuclear positioning and interchromosomal clustering of the GAL1-10 locus are controlled by separable, interdependent mechanisms.

Brickner DG, Sood V, Tutucci E, Coukos R, Viets K, Singer RH, Brickner JH.

Mol Biol Cell. 2016 Oct 1;27(19):2980-93. doi: 10.1091/mbc.E16-03-0174. Epub 2016 Aug 3.

39.

Translation dynamics of single mRNAs in live cells and neurons.

Wu B, Eliscovich C, Yoon YJ, Singer RH.

Science. 2016 Jun 17;352(6292):1430-5. doi: 10.1126/science.aaf1084. Epub 2016 May 5.

40.

Occupational Physical Activity and Body Mass Index: Results from the Hispanic Community Health Study/Study of Latinos.

Singer RH, Stoutenberg M, Gellman MD, Archer E, Davis SM, Gotman N, Marquez DX, Buelna C, Deng Y, Hosgood HD, Zambrana RE.

PLoS One. 2016 Mar 31;11(3):e0152339. doi: 10.1371/journal.pone.0152339. eCollection 2016.

41.

IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs.

Wang G, Huang Z, Liu X, Huang W, Chen S, Zhou Y, Li D, Singer RH, Gu W.

Oncotarget. 2016 Mar 29;7(13):15690-702. doi: 10.18632/oncotarget.7464.

42.
43.

Imaging Transcription: Past, Present, and Future.

Coleman RA, Liu Z, Darzacq X, Tjian R, Singer RH, Lionnet T.

Cold Spring Harb Symp Quant Biol. 2015;80:1-8. doi: 10.1101/sqb.2015.80.027201. Epub 2016 Jan 13. Review.

44.

Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes.

Katz ZB, English BP, Lionnet T, Yoon YJ, Monnier N, Ovryn B, Bathe M, Singer RH.

Elife. 2016 Jan 13;5. pii: e10415. doi: 10.7554/eLife.10415.

45.

Cellular Levels of Signaling Factors Are Sensed by β-actin Alleles to Modulate Transcriptional Pulse Intensity.

Kalo A, Kanter I, Shraga A, Sheinberger J, Tzemach H, Kinor N, Singer RH, Lionnet T, Shav-Tal Y.

Cell Rep. 2015 Nov 10;13(6):1284-1285. doi: 10.1016/j.celrep.2015.10.053. Epub 2015 Nov 10. No abstract available.

46.

Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer.

LoPiccolo J, Kim SJ, Shi Y, Wu B, Wu H, Chait BT, Singer RH, Sali A, Brenowitz M, Bresnick AR, Backer JM.

J Biol Chem. 2015 Dec 18;290(51):30390-405. doi: 10.1074/jbc.M115.689604. Epub 2015 Oct 16.

47.

CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells.

Deng W, Shi X, Tjian R, Lionnet T, Singer RH.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11870-5. doi: 10.1073/pnas.1515692112. Epub 2015 Aug 31.

48.

Inferring transient particle transport dynamics in live cells.

Monnier N, Barry Z, Park HY, Su KC, Katz Z, English BP, Dey A, Pan K, Cheeseman IM, Singer RH, Bathe M.

Nat Methods. 2015 Sep;12(9):838-40. doi: 10.1038/nmeth.3483. Epub 2015 Jul 20.

49.

Quantifying Protein-mRNA Interactions in Single Live Cells.

Wu B, Buxbaum AR, Katz ZB, Yoon YJ, Singer RH.

Cell. 2015 Jul 2;162(1):211-20. doi: 10.1016/j.cell.2015.05.054.

50.

Single-molecule insights into mRNA dynamics in neurons.

Buxbaum AR, Yoon YJ, Singer RH, Park HY.

Trends Cell Biol. 2015 Aug;25(8):468-75. doi: 10.1016/j.tcb.2015.05.005. Epub 2015 Jun 4. Review.

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