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Items: 1 to 50 of 439

1.

Selective PRMT5 inhibitors suppress human CD8+ T-cells by upregulation of p53 and impairment of the AKT pathway similar to the tumor metabolite MTA.

Strobl CD, Schaffer S, Haug T, Völkl S, Peter K, Singer K, Böttcher M, Mougiakakos D, Mackensen A, Aigner M.

Mol Cancer Ther. 2019 Nov 11. pii: molcanther.0189.2019. doi: 10.1158/1535-7163.MCT-19-0189. [Epub ahead of print]

PMID:
31712395
2.

Programming effects of maternal and gestational obesity on offspring metabolism and metabolic inflammation.

Chang E, Hafner H, Varghese M, Griffin C, Clemente J, Islam M, Carlson Z, Zhu A, Hak L, Abrishami S, Gregg B, Singer K.

Sci Rep. 2019 Nov 5;9(1):16027. doi: 10.1038/s41598-019-52583-x.

3.

Detection of ammonia on Pluto's surface in a region of geologically recent tectonism.

Dalle Ore CM, Cruikshank DP, Protopapa S, Scipioni F, McKinnon WB, Cook JC, Grundy WM, Schmitt B, Stern SA, Moore JM, Verbiscer A, Parker AH, Singer KN, Umurhan OM, Weaver HA, Olkin CB, Young LA, Ennico K.

Sci Adv. 2019 May 29;5(5):eaav5731. doi: 10.1126/sciadv.aav5731. eCollection 2019 May.

4.

Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.

Renner K, Bruss C, Schnell A, Koehl G, Becker HM, Fante M, Menevse AN, Kauer N, Blazquez R, Hacker L, Decking SM, Bohn T, Faerber S, Evert K, Aigle L, Amslinger S, Landa M, Krijgsman O, Rozeman EA, Brummer C, Siska PJ, Singer K, Pektor S, Miederer M, Peter K, Gottfried E, Herr W, Marchiq I, Pouyssegur J, Roush WR, Ong S, Warren S, Pukrop T, Beckhove P, Lang SA, Bopp T, Blank CU, Cleveland JL, Oefner PJ, Dettmer K, Selby M, Kreutz M.

Cell Rep. 2019 Oct 1;29(1):135-150.e9. doi: 10.1016/j.celrep.2019.08.068.

5.

Deterministic Single-Ion Implantation of Rare-Earth Ions for Nanometer-Resolution Color-Center Generation.

Groot-Berning K, Kornher T, Jacob G, Stopp F, Dawkins ST, Kolesov R, Wrachtrup J, Singer K, Schmidt-Kaler F.

Phys Rev Lett. 2019 Sep 6;123(10):106802. doi: 10.1103/PhysRevLett.123.106802.

PMID:
31573288
6.

Patient Experiences with the Use of Telephone Interpreter Services: An Exploratory, Qualitative Study of Spanish-Speaking Patients at an Urban Community Health Center.

Garcia-Jimenez M, Calvo-Friedman A, Singer K, Tanner M.

Narrat Inq Bioeth. 2019;9(2):149-162. doi: 10.1353/nib.2019.0027.

PMID:
31447453
7.

Sex Differences in Grant Funding.

Jagsi R, Singer K, Kerr E.

JAMA. 2019 Aug 13;322(6):578-580. doi: 10.1001/jama.2019.7840. No abstract available.

PMID:
31408127
8.

Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis.

Singer K, Dettmer K, Unger P, Schönhammer G, Renner K, Peter K, Siska PJ, Berneburg M, Herr W, Oefner PJ, Karrer S, Kreutz M, Datz E.

Front Oncol. 2019 Jul 3;9:605. doi: 10.3389/fonc.2019.00605. eCollection 2019.

9.

Lactational High-Fat Diet Exposure Programs Metabolic Inflammation and Bone Marrow Adiposity in Male Offspring.

Hafner H, Chang E, Carlson Z, Zhu A, Varghese M, Clemente J, Abrishami S, Bagchi DP, MacDougald OA, Singer K, Gregg B.

Nutrients. 2019 Jun 21;11(6). pii: E1393. doi: 10.3390/nu11061393.

10.

Impact of refugee influx on the epidemiology of late-presenting HIV-infected pregnant women and mother-to-child transmission: comparing a southern and northern medical centre in Germany.

Singer K, Schulze-Sturm U, Alba-Alejandre I, Hollwitz B, Nguyen TTT, Sollinger F, Eberle J, Hübner J, Kobbe R, Genzel-Boroviczény O, von Both U.

Infection. 2019 Oct;47(5):847-852. doi: 10.1007/s15010-019-01332-3. Epub 2019 Jun 12.

PMID:
31190299
11.

Reply.

Pesch MH, Tomlinson S, Singer K, Burrows HL.

J Pediatr. 2019 Aug;211:226. doi: 10.1016/j.jpeds.2019.05.007. Epub 2019 May 31. No abstract available.

PMID:
31160059
12.

Initial results from the New Horizons exploration of 2014 MU69, a small Kuiper Belt object.

Stern SA, Weaver HA, Spencer JR, Olkin CB, Gladstone GR, Grundy WM, Moore JM, Cruikshank DP, Elliott HA, McKinnon WB, Parker JW, Verbiscer AJ, Young LA, Aguilar DA, Albers JM, Andert T, Andrews JP, Bagenal F, Banks ME, Bauer BA, Bauman JA, Bechtold KE, Beddingfield CB, Behrooz N, Beisser KB, Benecchi SD, Bernardoni E, Beyer RA, Bhaskaran S, Bierson CJ, Binzel RP, Birath EM, Bird MK, Boone DR, Bowman AF, Bray VJ, Britt DT, Brown LE, Buckley MR, Buie MW, Buratti BJ, Burke LM, Bushman SS, Carcich B, Chaikin AL, Chavez CL, Cheng AF, Colwell EJ, Conard SJ, Conner MP, Conrad CA, Cook JC, Cooper SB, Custodio OS, Dalle Ore CM, Deboy CC, Dharmavaram P, Dhingra RD, Dunn GF, Earle AM, Egan AF, Eisig J, El-Maarry MR, Engelbrecht C, Enke BL, Ercol CJ, Fattig ED, Ferrell CL, Finley TJ, Firer J, Fischetti J, Folkner WM, Fosbury MN, Fountain GH, Freeze JM, Gabasova L, Glaze LS, Green JL, Griffith GA, Guo Y, Hahn M, Hals DW, Hamilton DP, Hamilton SA, Hanley JJ, Harch A, Harmon KA, Hart HM, Hayes J, Hersman CB, Hill ME, Hill TA, Hofgartner JD, Holdridge ME, Horányi M, Hosadurga A, Howard AD, Howett CJA, Jaskulek SE, Jennings DE, Jensen JR, Jones MR, Kang HK, Katz DJ, Kaufmann DE, Kavelaars JJ, Keane JT, Keleher GP, Kinczyk M, Kochte MC, Kollmann P, Krimigis SM, Kruizinga GL, Kusnierkiewicz DY, Lahr MS, Lauer TR, Lawrence GB, Lee JE, Lessac-Chenen EJ, Linscott IR, Lisse CM, Lunsford AW, Mages DM, Mallder VA, Martin NP, May BH, McComas DJ, McNutt RL Jr, Mehoke DS, Mehoke TS, Nelson DS, Nguyen HD, Núñez JI, Ocampo AC, Owen WM, Oxton GK, Parker AH, Pätzold M, Pelgrift JY, Pelletier FJ, Pineau JP, Piquette MR, Porter SB, Protopapa S, Quirico E, Redfern JA, Regiec AL, Reitsema HJ, Reuter DC, Richardson DC, Riedel JE, Ritterbush MA, Robbins SJ, Rodgers DJ, Rogers GD, Rose DM, Rosendall PE, Runyon KD, Ryschkewitsch MG, Saina MM, Salinas MJ, Schenk PM, Scherrer JR, Schlei WR, Schmitt B, Schultz DJ, Schurr DC, Scipioni F, Sepan RL, Shelton RG, Showalter MR, Simon M, Singer KN, Stahlheber EW, Stanbridge DR, Stansberry JA, Steffl AJ, Strobel DF, Stothoff MM, Stryk T, Stuart JR, Summers ME, Tapley MB, Taylor A, Taylor HW, Tedford RM, Throop HB, Turner LS, Umurhan OM, Van Eck J, Velez D, Versteeg MH, Vincent MA, Webbert RW, Weidner SE, Weigle GE 2nd, Wendel JR, White OL, Whittenburg KE, Williams BG, Williams KE, Williams SP, Winters HL, Zangari AM, Zurbuchen TH.

Science. 2019 May 17;364(6441). pii: eaaw9771. doi: 10.1126/science.aaw9771.

PMID:
31097641
13.

G-CSF partially mediates effects of sleeve gastrectomy on the bone marrow niche.

Li Z, Hardij J, Evers SS, Hutch CR, Choi SM, Shao Y, Learman BS, Lewis KT, Schill RL, Mori H, Bagchi DP, Romanelli SM, Kim KS, Bowers E, Griffin C, Seeley RJ, Singer K, Sandoval DA, Rosen CJ, MacDougald OA.

J Clin Invest. 2019 May 6;129(6):2404-2416. doi: 10.1172/JCI126173. eCollection 2019 May 6.

14.

Proposed endocrine funding priorities for the NICHD strategic plan: expert opinion from the Pediatric Endocrine Society.

Singer K, Katz ML, Mittelman SD; PES Research Affairs Committee.

Pediatr Res. 2019 Aug;86(2):141-143. doi: 10.1038/s41390-019-0401-0. Epub 2019 Apr 17. No abstract available.

15.

Inflammatory responses to dietary and surgical weight loss in male and female mice.

Griffin C, Hutch CR, Abrishami S, Stelmak D, Eter L, Li Z, Chang E, Agarwal D, Zamarron B, Varghese M, Subbaiah P, MacDougald OA, Sandoval DA, Singer K.

Biol Sex Differ. 2019 Apr 3;10(1):16. doi: 10.1186/s13293-019-0229-7.

16.

Impact craters on Pluto and Charon indicate a deficit of small Kuiper belt objects.

Singer KN, McKinnon WB, Gladman B, Greenstreet S, Bierhaus EB, Stern SA, Parker AH, Robbins SJ, Schenk PM, Grundy WM, Bray VJ, Beyer RA, Binzel RP, Weaver HA, Young LA, Spencer JR, Kavelaars JJ, Moore JM, Zangari AM, Olkin CB, Lauer TR, Lisse CM, Ennico K; New Horizons Geology, Geophysics and Imaging Science Theme Team; New Horizons Surface Composition Science Theme Team; New Horizons Ralph and LORRI Teams.

Science. 2019 Mar 1;363(6430):955-959. doi: 10.1126/science.aap8628.

PMID:
30819958
17.

Pediatricians Advocating Breastfeeding: Let's Start with Supporting our Fellow Pediatricians First.

Pesch MH, Tomlinson S, Singer K, Burrows HL.

J Pediatr. 2019 Mar;206:6-7. doi: 10.1016/j.jpeds.2018.12.057. No abstract available.

PMID:
30798838
18.

D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells.

Ugele I, Cárdenas-Conejo ZE, Hammon K, Wehrstein M, Bruss C, Peter K, Singer K, Gottfried E, Boesch J, Oefner P, Dettmer K, Renner K, Kreutz M.

Int J Mol Sci. 2019 Feb 10;20(3). pii: E742. doi: 10.3390/ijms20030742.

19.

Histone Methylation Directs Myeloid TLR4 Expression and Regulates Wound Healing following Cutaneous Tissue Injury.

Davis FM, Kimball A, denDekker A, Joshi AD, Boniakowski AE, Nysz D, Allen RM, Obi A, Singer K, Henke PK, Moore BB, Kunkel SL, Gallagher KA.

J Immunol. 2019 Mar 15;202(6):1777-1785. doi: 10.4049/jimmunol.1801258. Epub 2019 Feb 1.

PMID:
30710046
20.

Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary?

Hoehn RS, Seitz AP, Singer KE, Thompson JR, Watkins BM.

J Gastrointest Surg. 2019 Aug;23(8):1541-1546. doi: 10.1007/s11605-018-04091-y. Epub 2019 Jan 28.

PMID:
30693426
21.

Sex Differences in Inflammatory Responses to Adipose Tissue Lipolysis in Diet-Induced Obesity.

Varghese M, Griffin C, McKernan K, Eter L, Lanzetta N, Agarwal D, Abrishami S, Singer K.

Endocrinology. 2019 Feb 1;160(2):293-312. doi: 10.1210/en.2018-00797.

PMID:
30544158
22.

Combined Metabolic Targeting With Metformin and the NSAIDs Diflunisal and Diclofenac Induces Apoptosis in Acute Myeloid Leukemia Cells.

Renner K, Seilbeck A, Kauer N, Ugele I, Siska PJ, Brummer C, Bruss C, Decking SM, Fante M, Schmidt A, Hammon K, Singer K, Klobuch S, Thomas S, Gottfried E, Peter K, Kreutz M.

Front Pharmacol. 2018 Nov 2;9:1258. doi: 10.3389/fphar.2018.01258. eCollection 2018.

23.

Grown Ultrathin Bacterial Cellulose Mats for Optical Applications.

Liu F, McMaster M, Mekala S, Singer K, Gross RA.

Biomacromolecules. 2018 Dec 10;19(12):4576-4584. doi: 10.1021/acs.biomac.8b01269. Epub 2018 Nov 5.

PMID:
30354071
24.

The NASA Roadmap to Ocean Worlds.

Hendrix AR, Hurford TA, Barge LM, Bland MT, Bowman JS, Brinckerhoff W, Buratti BJ, Cable ML, Castillo-Rogez J, Collins GC, Diniega S, German CR, Hayes AG, Hoehler T, Hosseini S, Howett CJA, McEwen AS, Neish CD, Neveu M, Nordheim TA, Patterson GW, Patthoff DA, Phillips C, Rhoden A, Schmidt BE, Singer KN, Soderblom JM, Vance SD.

Astrobiology. 2019 Jan;19(1):1-27. doi: 10.1089/ast.2018.1955. Epub 2018 Oct 13.

25.

Supporting people with intellectual disabilities in psychological therapies for depression: A qualitative analysis of supporters' experiences.

Scott K, Hatton C, Knight R, Singer K, Knowles D, Dagnan D, Hastings RP, Appleton K, Cooper SA, Melville C, Jones R, Williams C, Jahoda A.

J Appl Res Intellect Disabil. 2019 Mar;32(2):323-335. doi: 10.1111/jar.12529. Epub 2018 Sep 28. Erratum in: J Appl Res Intellect Disabil. 2019 Jul;32(4):1006.

PMID:
30264419
26.

Biosurfactant-functionalized porphyrin chromophore that forms J-aggregates.

Mekala S, Peters KC, Singer KD, Gross RA.

Org Biomol Chem. 2018 Oct 10;16(39):7178-7190. doi: 10.1039/c8ob01655k.

PMID:
30252014
27.

Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.

Ždralević M, Brand A, Di Ianni L, Dettmer K, Reinders J, Singer K, Peter K, Schnell A, Bruss C, Decking SM, Koehl G, Felipe-Abrio B, Durivault J, Bayer P, Evangelista M, O'Brien T, Oefner PJ, Renner K, Pouysségur J, Kreutz M.

J Biol Chem. 2018 Oct 12;293(41):15947-15961. doi: 10.1074/jbc.RA118.004180. Epub 2018 Aug 29.

28.

Water-fat magnetic resonance imaging quantifies relative proportions of brown and white adipose tissues: ex-vivo experiments.

Stojanovska J, Lumeng CN, Griffin C, Hernando D, Hoffmann U, Haft JW, Kim KM, Burant CF, Singer K, Tsodikov A, Long BD, Romano MA, Tang PC, Yang B, Chenevert TL.

J Med Imaging (Bellingham). 2018 Apr;5(2):024007. doi: 10.1117/1.JMI.5.2.024007. Epub 2018 Jun 29.

29.

Immunometabolism in cancer at a glance.

Singer K, Cheng WC, Kreutz M, Ho PC, Siska PJ.

Dis Model Mech. 2018 Aug 2;11(8). pii: dmm034272. doi: 10.1242/dmm.034272. Review.

30.

Gender and Sex Differences in Adipose Tissue.

Chang E, Varghese M, Singer K.

Curr Diab Rep. 2018 Jul 30;18(9):69. doi: 10.1007/s11892-018-1031-3. Review.

31.

Fatal pitfalls in newborn screening for mitochondrial trifunctional protein (MTP)/long-chain 3-Hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency.

Lotz-Havla AS, Röschinger W, Schiergens K, Singer K, Karall D, Konstantopoulou V, Wortmann SB, Maier EM.

Orphanet J Rare Dis. 2018 Jul 20;13(1):122. doi: 10.1186/s13023-018-0875-6.

32.

The Mechanism of T-DNA Integration: Some Major Unresolved Questions.

Singer K.

Curr Top Microbiol Immunol. 2018;418:287-317. doi: 10.1007/82_2018_98. Review.

PMID:
29992359
33.

Preserving Future Generations of Pediatric Researchers.

Gállego Suárez C, Gregg BE, Watson ME Jr, Sturza J, Bermick JR, Singer K.

J Pediatr. 2018 May;196:4-6. doi: 10.1016/j.jpeds.2018.01.061. No abstract available.

34.

TLR4, TRIF, and MyD88 are essential for myelopoiesis and CD11c+ adipose tissue macrophage production in obese mice.

Griffin C, Eter L, Lanzetta N, Abrishami S, Varghese M, McKernan K, Muir L, Lane J, Lumeng CN, Singer K.

J Biol Chem. 2018 Jun 8;293(23):8775-8786. doi: 10.1074/jbc.RA117.001526. Epub 2018 Apr 10.

35.

Dielectric Properties of Bio-Based Diphenolate Ester Epoxies.

McMaster MS, Yilmaz TE, Patel A, Maiorana A, Manas-Zloczower I, Gross R, Singer KD.

ACS Appl Mater Interfaces. 2018 Apr 25;10(16):13924-13930. doi: 10.1021/acsami.7b19085. Epub 2018 Apr 16.

PMID:
29620846
36.

Frontline Science: Rapid adipose tissue expansion triggers unique proliferation and lipid accumulation profiles in adipose tissue macrophages.

Muir LA, Kiridena S, Griffin C, DelProposto JB, Geletka L, Martinez-Santibañez G, Zamarron BF, Lucas H, Singer K, O' Rourke RW, Lumeng CN.

J Leukoc Biol. 2018 Apr;103(4):615-628. doi: 10.1002/JLB.3HI1017-422R. Epub 2018 Mar 1.

37.

Change in Low Back Movement Patterns After Neurosurgical Intervention for Lumbar Spondylosis.

Monie AP, Price RI, Lind CRP, Singer KP.

J Manipulative Physiol Ther. 2018 Feb;41(2):111-122. doi: 10.1016/j.jmpt.2017.08.008.

PMID:
29482826
38.

Outcomes and Resource Use Among Overweight and Obese Children With Sepsis in the Pediatric Intensive Care Unit.

Peterson LS, Gállego Suárez C, Segaloff HE, Griffin C, Martin ET, Odetola FO, Singer K.

J Intensive Care Med. 2018 Jan 1:885066618760541. doi: 10.1177/0885066618760541. [Epub ahead of print]

39.

The Role of Sex and Sex Hormones in Regulating Obesity-Induced Inflammation.

Varghese M, Griffin C, Singer K.

Adv Exp Med Biol. 2017;1043:65-86. doi: 10.1007/978-3-319-70178-3_5. Review.

PMID:
29224091
40.

Mouse adenovirus type 1 infection of adipose tissue.

Molloy CT, Adkins LJ, Griffin C, Singer K, Weinberg JB.

Virus Res. 2018 Jan 15;244:90-98. doi: 10.1016/j.virusres.2017.11.014. Epub 2017 Nov 12.

PMID:
29141203
41.

Charon tectonics.

Beyer RA, Nimmo F, McKinnon WB, Moore JM, Binzel RP, Conrad JW, Cheng A, Ennico K, Lauer TR, Olkin CB, Robbins S, Schenk P, Singer K, Spencer JR, Stern SA, Weaver HA, Young LA, Zangari AM.

Icarus. 2017 May 1;287:161-174. doi: 10.1016/j.icarus.2016.12.018. Epub 2016 Dec 16.

42.

The relationship between adiposity and bone density in U.S. children and adolescents.

Gállego Suárez C, Singer BH, Gebremariam A, Lee JM, Singer K.

PLoS One. 2017 Jul 19;12(7):e0181587. doi: 10.1371/journal.pone.0181587. eCollection 2017.

43.

Searching for Biosignatures in Exoplanetary Impact Ejecta.

Cataldi G, Brandeker A, Thébault P, Singer K, Ahmed E, de Vries BL, Neubeck A, Olofsson G.

Astrobiology. 2017 Aug;17(8):721-746. doi: 10.1089/ast.2015.1437. Epub 2017 Jul 10.

PMID:
28692303
44.

Outpatient beta-blockers and survival from sepsis: Results from a national cohort of Medicare beneficiaries.

Singer KE, Collins CE, Flahive JM, Wyman AS, Ayturk MD, Santry HP.

Am J Surg. 2017 Oct;214(4):577-582. doi: 10.1016/j.amjsurg.2017.06.007. Epub 2017 Jun 24.

PMID:
28666578
45.

Insulin Bolus Calculator in a Pediatric Hospital. Safety and User Perceptions.

Ateya MB, Aiyagari R, Moran C, Singer K.

Appl Clin Inform. 2017 May 24;8(2):529-540. doi: 10.4338/ACI-2016-11-RA-0187.

46.

Adipocyte hypertrophy-hyperplasia balance contributes to weight loss after bariatric surgery.

Muir LA, Baker NA, Washabaugh AR, Neeley CK, Flesher CG, DelProposto JB, Geletka LM, Ghaferi AA, Finks JF, Singer K, Varban OA, Lumeng CN, O'Rourke RW.

Adipocyte. 2017 Apr 3;6(2):134-140. doi: 10.1080/21623945.2017.1287639. Epub 2017 Jan 27.

47.

Structure-Specific Movement Patterns in Patients With Chronic Low Back Dysfunction Using Lumbar Combined Movement Examination.

Monie AP, Price RI, Lind CRP, Singer KP.

J Manipulative Physiol Ther. 2017 Jun;40(5):340-349. doi: 10.1016/j.jmpt.2017.02.011. Epub 2017 Apr 14.

PMID:
28413117
48.

Metabolic Hallmarks of Tumor and Immune Cells in the Tumor Microenvironment.

Renner K, Singer K, Koehl GE, Geissler EK, Peter K, Siska PJ, Kreutz M.

Front Immunol. 2017 Mar 8;8:248. doi: 10.3389/fimmu.2017.00248. eCollection 2017. Review.

49.

Ophthalmic Screening Patterns Among Youths With Diabetes Enrolled in a Large US Managed Care Network.

Wang SY, Andrews CA, Gardner TW, Wood M, Singer K, Stein JD.

JAMA Ophthalmol. 2017 May 1;135(5):432-438. doi: 10.1001/jamaophthalmol.2017.0089.

50.

Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice.

Zamarron BF, Mergian TA, Cho KW, Martinez-Santibanez G, Luan D, Singer K, DelProposto JL, Geletka LM, Muir LA, Lumeng CN.

Diabetes. 2017 Feb;66(2):392-406. doi: 10.2337/db16-0500. Epub 2016 Nov 8.

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