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Items: 15


Prospective isolation of radiation induced erythroid stress progenitors reveals unique transcriptomic and epigenetic signatures enabling increased erythroid output.

Singbrant S, Mattebo A, Sigvardsson M, Strid T, Flygare J.

Haematologica. 2020 Jan 9. pii: haematol.2019.234542. doi: 10.3324/haematol.2019.234542. [Epub ahead of print]


Technical considerations for the use of CRISPR/Cas9 in hematology research.

Gundry MC, Dever DP, Yudovich D, Bauer DE, Haas S, Wilkinson AC, Singbrant S.

Exp Hematol. 2017 Oct;54:4-11. doi: 10.1016/j.exphem.2017.07.006. Epub 2017 Jul 27. Review.


The evolving view of the hematopoietic stem cell niche.

Beerman I, Luis TC, Singbrant S, Lo Celso C, Méndez-Ferrer S.

Exp Hematol. 2017 Jun;50:22-26. doi: 10.1016/j.exphem.2017.01.008. Epub 2017 Feb 9. Review.


Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion.

Capellera-Garcia S, Pulecio J, Dhulipala K, Siva K, Rayon-Estrada V, Singbrant S, Sommarin MN, Walkley CR, Soneji S, Karlsson G, Raya Á, Sankaran VG, Flygare J.

Cell Rep. 2016 Jun 14;15(11):2550-62. doi: 10.1016/j.celrep.2016.05.027. Epub 2016 Jun 2.


Gene expression profiling to define the cell intrinsic role of the SKI proto-oncogene in hematopoiesis and myeloid neoplasms.

Chalk AM, Liddicoat BJ, Walkley CR, Singbrant S.

Genom Data. 2014 Jul 4;2:189-91. doi: 10.1016/j.gdata.2014.06.022. eCollection 2014 Dec.


Two new routes to make blood: Hematopoietic specification from pluripotent cell lines versus reprogramming of somatic cells.

Singbrant S, van Galen P, Lucas D, Challen G, Rossi DJ, Daley GQ.

Exp Hematol. 2015 Sep;43(9):756-9. doi: 10.1016/j.exphem.2015.05.007. Epub 2015 Jul 2. Review.


Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts.

Le Goff B, Singbrant S, Tonkin BA, Martin TJ, Romas E, Sims NA, Walsh NC.

Cytokine. 2014 Aug;68(2):101-9. doi: 10.1016/j.cyto.2014.04.001. Epub 2014 Apr 22.


The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease.

Singbrant S, Wall M, Moody J, Karlsson G, Chalk AM, Liddicoat B, Russell MR, Walkley CR, Karlsson S.

Haematologica. 2014 Apr;99(4):647-55. doi: 10.3324/haematol.2013.093971. Epub 2014 Jan 10.


Defining the hematopoietic stem cell niche: the chicken and the egg conundrum.

Singbrant S, Askmyr M, Purton LE, Walkley CR.

J Cell Biochem. 2011 Jun;112(6):1486-90. doi: 10.1002/jcb.23085. Review.


Erythropoietin couples erythropoiesis, B-lymphopoiesis, and bone homeostasis within the bone marrow microenvironment.

Singbrant S, Russell MR, Jovic T, Liddicoat B, Izon DJ, Purton LE, Sims NA, Martin TJ, Sankaran VG, Walkley CR.

Blood. 2011 May 26;117(21):5631-42. doi: 10.1182/blood-2010-11-320564. Epub 2011 Mar 18.


Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.

Singbrant S, Karlsson G, Ehinger M, Olsson K, Jaako P, Miharada K, Stadtfeld M, Graf T, Karlsson S.

Blood. 2010 Jun 10;115(23):4689-98. doi: 10.1182/blood-2009-05-220988. Epub 2010 Apr 6.


Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development.

Moody JL, Singbrant S, Karlsson G, Blank U, Aspling M, Flygare J, Bryder D, Karlsson S.

Stem Cells. 2007 Nov;25(11):2809-19. Epub 2007 Aug 2.


Smad4 is critical for self-renewal of hematopoietic stem cells.

Karlsson G, Blank U, Moody JL, Ehinger M, Singbrant S, Deng CX, Karlsson S.

J Exp Med. 2007 Mar 19;204(3):467-74. Epub 2007 Mar 12.


Smad7 promotes self-renewal of hematopoietic stem cells.

Blank U, Karlsson G, Moody JL, Utsugisawa T, Magnusson M, Singbrant S, Larsson J, Karlsson S.

Blood. 2006 Dec 15;108(13):4246-54. Epub 2006 Aug 17.


Smad5 is dispensable for adult murine hematopoiesis.

Singbrant S, Moody JL, Blank U, Karlsson G, Umans L, Zwijsen A, Karlsson S.

Blood. 2006 Dec 1;108(12):3707-12. Epub 2006 Aug 8.


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