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Items: 7


Quantitative Lipid Imaging Reveals a New Signaling Function of Phosphatidylinositol-3,4-Bisphophate: Isoform- and Site-Specific Activation of Akt.

Liu SL, Wang ZG, Hu Y, Xin Y, Singaram I, Gorai S, Zhou X, Shim Y, Min JH, Gong LW, Hay N, Zhang J, Cho W.

Mol Cell. 2018 Sep 20;71(6):1092-1104.e5. doi: 10.1016/j.molcel.2018.07.035. Epub 2018 Aug 30.


Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3,4,5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain.

Kim E, Kim DH, Singaram I, Jeong H, Koh A, Lee J, Cho W, Ryu SH.

Cell Signal. 2018 Nov;51:130-138. doi: 10.1016/j.cellsig.2018.07.009. Epub 2018 Aug 7.


Structure and Dynamics of Membrane Proteins and Membrane Associated Proteins with Native Bicelles from Eukaryotic Tissues.

Smrt ST, Draney AW, Singaram I, Lorieau JL.

Biochemistry. 2017 Oct 10;56(40):5318-5327. doi: 10.1021/acs.biochem.7b00575. Epub 2017 Sep 27.


α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion.

Wood MN, Ishiyama N, Singaram I, Chung CM, Flozak AS, Yemelyanov A, Ikura M, Cho W, Gottardi CJ.

J Cell Biol. 2017 Nov 6;216(11):3767-3783. doi: 10.1083/jcb.201612006. Epub 2017 Sep 5.


SH3 Domain-Containing Protein 2 Plays a Crucial Role at the Step of Membrane Tubulation during Cell Plate Formation.

Ahn G, Kim H, Kim DH, Hanh H, Yoon Y, Singaram I, Wijesinghe KJ, Johnson KA, Zhuang X, Liang Z, Stahelin RV, Jiang L, Cho W, Kang BH, Hwang I.

Plant Cell. 2017 Jun;29(6):1388-1405. doi: 10.1105/tpc.17.00108. Epub 2017 Jun 5.


Lipids Regulate Lck Protein Activity through Their Interactions with the Lck Src Homology 2 Domain.

Sheng R, Jung DJ, Silkov A, Kim H, Singaram I, Wang ZG, Xin Y, Kim E, Park MJ, Thiagarajan-Rosenkranz P, Smrt S, Honig B, Baek K, Ryu S, Lorieau J, Kim YM, Cho W.

J Biol Chem. 2016 Aug 19;291(34):17639-50. doi: 10.1074/jbc.M116.720284. Epub 2016 Jun 22.


SH2 Domains Serve as Lipid-Binding Modules for pTyr-Signaling Proteins.

Park MJ, Sheng R, Silkov A, Jung DJ, Wang ZG, Xin Y, Kim H, Thiagarajan-Rosenkranz P, Song S, Yoon Y, Nam W, Kim I, Kim E, Lee DG, Chen Y, Singaram I, Wang L, Jang MH, Hwang CS, Honig B, Ryu S, Lorieau J, Kim YM, Cho W.

Mol Cell. 2016 Apr 7;62(1):7-20. doi: 10.1016/j.molcel.2016.01.027. Epub 2016 Mar 24.

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