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Items: 1 to 50 of 386

1.

Decreased telomere length in the small airway epithelium suggests accelerated aging in the lungs of persons living with human immunodeficiency virus (HIV).

Xu S, Vucic EA, Shaipanich T, Lam S, Lam W, Montaner JS, Sin DD, Paul Man SF, Leung JM.

Respir Res. 2018 Jun 13;19(1):117. doi: 10.1186/s12931-018-0821-0.

2.

Emergency department management of acute exacerbations of chronic obstructive pulmonary disease: factors predicting readmission.

Bartels W, Adamson S, Leung L, Sin DD, van Eeden SF.

Int J Chron Obstruct Pulmon Dis. 2018 May 23;13:1647-1654. doi: 10.2147/COPD.S163250. eCollection 2018.

3.

Long-Term Trajectories of Mild Asthma in Adulthood and Risk Factors of Progression.

Chen W, FitzGerald JM, Lynd LD, Sin DD, Sadatsafavi M.

J Allergy Clin Immunol Pract. 2018 May 7. pii: S2213-2198(18)30304-0. doi: 10.1016/j.jaip.2018.04.027. [Epub ahead of print]

PMID:
29746917
4.

Pulmonary Vascular Involvement in COPD - Is There a Pulmonary Vascular Phenotype?

Kovacs G, Agusti A, Barberà JA, Celli B, Criner G, Humbert M, Sin DD, Voelkel N, Olschewski H.

Am J Respir Crit Care Med. 2018 May 10. doi: 10.1164/rccm.201801-0095PP. [Epub ahead of print]

PMID:
29746142
5.

Crisis of COPD in China: the future is now.

Sun Y, Sin DD.

Lancet Respir Med. 2018 Jun;6(6):404-405. doi: 10.1016/S2213-2600(18)30133-4. Epub 2018 Apr 9. No abstract available.

PMID:
29650406
6.

The genetics of smoking in individuals with chronic obstructive pulmonary disease.

Obeidat M, Zhou G, Li X, Hansel NN, Rafaels N, Mathias R, Ruczinski I, Beaty TH, Barnes KC, Paré PD, Sin DD.

Respir Res. 2018 Apr 10;19(1):59. doi: 10.1186/s12931-018-0762-7.

7.

COPD and cardiovascular diseases: now is the time for action!

Leitao Filho FS, Sin DD.

Thorax. 2018 Apr 5. pii: thoraxjnl-2018-211553. doi: 10.1136/thoraxjnl-2018-211553. [Epub ahead of print] No abstract available.

PMID:
29622696
8.

The Impact of Care Specialty on Survival-Adjusted Medical Costs of COPD Patients After a Hospitalization: a longitudinal analysis.

Chen W, Sin DD, FitzGerald JM, Sadatsafavi M; Canadian Respiratory Research Network.

J Gen Intern Med. 2018 Apr 2. doi: 10.1007/s11606-018-4406-x. [Epub ahead of print]

PMID:
29611088
9.

Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations.

Lamontagne M, Bérubé JC, Obeidat M, Cho MH, Hobbs BD, Sakornsakolpat P, de Jong K, Boezen HM; International COPD Genetics Consortium, Nickle D, Hao K, Timens W, van den Berge M, Joubert P, Laviolette M, Sin DD, Paré PD, Bossé Y.

Hum Mol Genet. 2018 May 15;27(10):1819-1829. doi: 10.1093/hmg/ddy091.

PMID:
29547942
10.

COPD as a Risk Factor for Cardiovascular Disease: A View from the SUMMIT.

Hurst JR, Sin DD.

Am J Respir Crit Care Med. 2018 Mar 13. doi: 10.1164/rccm.201802-0347ED. [Epub ahead of print] No abstract available.

PMID:
29533679
11.

Favorable longitudinal change of lung function in patients with asthma-COPD overlap from a COPD cohort.

Park HY, Lee SY, Kang D, Cho J, Lee H, Lim SY, Yoon HI, Ra SW, Kim KU, Oh YM, Sin DD, Lee SD, Park YB.

Respir Res. 2018 Mar 2;19(1):36. doi: 10.1186/s12931-018-0737-8.

12.

Large-scale external validation and comparison of prognostic models: an application to chronic obstructive pulmonary disease.

Guerra B, Haile SR, Lamprecht B, Ramírez AS, Martinez-Camblor P, Kaiser B, Alfageme I, Almagro P, Casanova C, Esteban-González C, Soler-Cataluña JJ, de-Torres JP, Miravitlles M, Celli BR, Marin JM, Ter Riet G, Sobradillo P, Lange P, Garcia-Aymerich J, Antó JM, Turner AM, Han MK, Langhammer A, Leivseth L, Bakke P, Johannessen A, Oga T, Cosio B, Ancochea-Bermúdez J, Echazarreta A, Roche N, Burgel PR, Sin DD, Soriano JB, Puhan MA; 3CIA collaboration.

BMC Med. 2018 Mar 2;16(1):33. doi: 10.1186/s12916-018-1013-y.

13.

Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD.

Leitao Filho FS, Ra SW, Mattman A, Schellenberg RS, Criner GJ, Woodruff PG, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Leung JM, Paul Man SF, Aaron SD, Reed RM, Sin DD; Canadian Respiratory Research Network (CRRN).

Respir Res. 2018 Feb 14;19(1):30. doi: 10.1186/s12931-018-0733-z.

14.

Characterizing undiagnosed chronic obstructive pulmonary disease: a systematic review and meta-analysis.

Johnson KM, Bryan S, Ghanbarian S, Sin DD, Sadatsafavi M.

Respir Res. 2018 Feb 7;19(1):26. doi: 10.1186/s12931-018-0731-1.

15.

Response.

Raymakers AJN, Sadatsafavi M, Sin DD, De Vera MA, Lynd LD.

Chest. 2018 Feb;153(2):578-579. doi: 10.1016/j.chest.2017.12.006. No abstract available.

PMID:
29406228
16.

Inhaled Corticosteroids and Fractures in COPD: Can We Finally Put This to Bed?

Cho YJ, Sin DD.

Chest. 2018 Feb;153(2):293-294. doi: 10.1016/j.chest.2017.08.027. No abstract available.

PMID:
29406210
17.

Phenotyping COPD exacerbations using imaging and blood-based biomarkers.

Alotaibi NM, Chen V, Hollander Z, Hague CJ, Murphy DT, Leipsic JA, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.

Int J Chron Obstruct Pulmon Dis. 2018 Jan 8;13:217-229. doi: 10.2147/COPD.S152484. eCollection 2018.

18.

Multiple Score Comparison: a network meta-analysis approach to comparison and external validation of prognostic scores.

Haile SR, Guerra B, Soriano JB, Puhan MA; 3CIA collaboration.

BMC Med Res Methodol. 2017 Dec 21;17(1):172. doi: 10.1186/s12874-017-0433-2. Erratum in: BMC Med Res Methodol. 2018 Feb 12;18(1):21.

19.

The role of beta-blockers in the management of chronic obstructive pulmonary disease.

Leitao Filho FS, Alotaibi NM, Yamasaki K, Ngan DA, Sin DD.

Expert Rev Respir Med. 2018 Feb;12(2):125-135. doi: 10.1080/17476348.2018.1419869. Epub 2017 Dec 27.

PMID:
29258360
20.

Reply.

Leitao Filho FS, Ra SW, Mattman A, Schellenberg RS, Sin DD.

J Allergy Clin Immunol. 2018 Feb;141(2):831. doi: 10.1016/j.jaci.2017.10.013. Epub 2017 Dec 6. No abstract available.

PMID:
29221816
21.

Lung tissue gene-expression signature for the ageing lung in COPD.

de Vries M, Faiz A, Woldhuis RR, Postma DS, de Jong TV, Sin DD, Bossé Y, Nickle DC, Guryev V, Timens W, van den Berge M, Brandsma CA.

Thorax. 2017 Dec 6. pii: thoraxjnl-2017-210074. doi: 10.1136/thoraxjnl-2017-210074. [Epub ahead of print]

PMID:
29212667
22.

Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation.

Obeidat M, Li X, Burgess S, Zhou G, Fishbane N, Hansel NN, Bossé Y, Joubert P, Hao K, Nickle DC, van den Berge M, Timens W, Cho MH, Hobbs BD, de Jong K, Boezen M, Hung RJ, Rafaels N, Mathias R, Ruczinski I, Beaty TH, Barnes KC, Paré PD, Sin DD; International COPD Genetics Consortium, Lung eQTL Consortium, Lung Health Study.

Eur Respir J. 2017 Nov 30;50(5). pii: 1700657. doi: 10.1183/13993003.00657-2017. Print 2017 Nov.

PMID:
29191953
23.

Multiple reaction monitoring mass spectrometry to identify novel plasma protein biomarkers of treatment response in cystic fibrosis pulmonary exacerbations.

Roberts JM, Dai DLY, Hollander Z, Ng RT, Tebbutt SJ, Wilcox PG, Sin DD, Quon BS.

J Cyst Fibros. 2018 May;17(3):333-340. doi: 10.1016/j.jcf.2017.10.013. Epub 2017 Nov 22.

PMID:
29174082
24.

A simple algorithm for the identification of clinical COPD phenotypes.

Burgel PR, Paillasseur JL, Janssens W, Piquet J, Ter Riet G, Garcia-Aymerich J, Cosio B, Bakke P, Puhan MA, Langhammer A, Alfageme I, Almagro P, Ancochea J, Celli BR, Casanova C, de-Torres JP, Decramer M, Echazarreta A, Esteban C, Gomez Punter RM, Han MK, Johannessen A, Kaiser B, Lamprecht B, Lange P, Leivseth L, Marin JM, Martin F, Martinez-Camblor P, Miravitlles M, Oga T, Sofia Ramírez A, Sin DD, Sobradillo P, Soler-Cataluña JJ, Turner AM, Verdu Rivera FJ, Soriano JB, Roche N; Initiatives BPCO, EABPCO, Leuven and 3CIA study groups.

Eur Respir J. 2017 Nov 2;50(5). pii: 1701034. doi: 10.1183/13993003.01034-2017. Print 2017 Nov.

PMID:
29097431
25.

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.

Allen RJ, Porte J, Braybrooke R, Flores C, Fingerlin TE, Oldham JM, Guillen-Guio B, Ma SF, Okamoto T, John AE, Obeidat M, Yang IV, Henry A, Hubbard RB, Navaratnam V, Saini G, Thompson N, Booth HL, Hart SP, Hill MR, Hirani N, Maher TM, McAnulty RJ, Millar AB, Molyneaux PL, Parfrey H, Rassl DM, Whyte MKB, Fahy WA, Marshall RP, Oballa E, Bossé Y, Nickle DC, Sin DD, Timens W, Shrine N, Sayers I, Hall IP, Noth I, Schwartz DA, Tobin MD, Wain LV, Jenkins RG.

Lancet Respir Med. 2017 Nov;5(11):869-880. doi: 10.1016/S2213-2600(17)30387-9. Epub 2017 Oct 20.

26.

Serum bilirubin and the risk of chronic obstructive pulmonary disease exacerbations.

Brown KE, Sin DD, Voelker H, Connett JE, Niewoehner DE, Kunisaki KM; COPD Clinical Research Network.

Respir Res. 2017 Oct 24;18(1):179. doi: 10.1186/s12931-017-0664-0.

27.

Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study.

Tammemagi MC, Schmidt H, Martel S, McWilliams A, Goffin JR, Johnston MR, Nicholas G, Tremblay A, Bhatia R, Liu G, Soghrati K, Yasufuku K, Hwang DM, Laberge F, Gingras M, Pasian S, Couture C, Mayo JR, Nasute Fauerbach PV, Atkar-Khattra S, Peacock SJ, Cressman S, Ionescu D, English JC, Finley RJ, Yee J, Puksa S, Stewart L, Tsai S, Haider E, Boylan C, Cutz JC, Manos D, Xu Z, Goss GD, Seely JM, Amjadi K, Sekhon HS, Burrowes P, MacEachern P, Urbanski S, Sin DD, Tan WC, Leighl NB, Shepherd FA, Evans WK, Tsao MS, Lam S; PanCan Study Team.

Lancet Oncol. 2017 Nov;18(11):1523-1531. doi: 10.1016/S1470-2045(17)30597-1. Epub 2017 Oct 18.

PMID:
29055736
28.

Survival of Lung Transplant Candidates With COPD: BODE Score Reconsidered.

Reed RM, Cabral HJ, Dransfield MT, Eberlein M, Merlo CA, Mulligan MJ, Netzer G, Sanchez PG, Scharf SM, Sin DD, Celli BR.

Chest. 2018 Mar;153(3):697-701. doi: 10.1016/j.chest.2017.10.008. Epub 2017 Oct 17.

PMID:
29054348
29.

Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets.

Leung JM, Sin DD.

BMJ. 2017 Sep 25;358:j3772. doi: 10.1136/bmj.j3772. Review.

PMID:
28947632
30.

Work productivity loss in mild to moderate COPD: lessons learned from the CanCOLD study.

de Sousa Sena R, Ahmed S, Tan WC, Li PZ, Labonté L, Aaron SD, Benedetti A, Chapman KR, Walker B, Fitzgerald JM, Hernandez P, Maltais F, Marciniuk DD, O'Donnell DE, Sin DD, Bourbeau J; CanCOLD Collaborative Research Group and The Canadian Respiratory Research Network.

Eur Respir J. 2017 Sep 12;50(3). pii: 1701154. doi: 10.1183/13993003.01154-2017. Print 2017 Sep. No abstract available.

PMID:
28899939
31.

Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study.

Kirby M, Tanabe N, Tan WC, Zhou G, Obeidat M, Hague CJ, Leipsic J, Bourbeau J, Sin DD, Hogg JC, Coxson HO; CanCOLD Collaborative Research Group; Canadian Respiratory Research Network; CanCOLD Collaborative Research Group, the Canadian Respiratory Research Network.

Am J Respir Crit Care Med. 2018 Jan 1;197(1):56-65. doi: 10.1164/rccm.201704-0692OC.

PMID:
28886252
32.

Global Initiative for Chronic Obstructive Lung Disease 2017 Classification and Lung Function Decline in Chronic Obstructive Pulmonary Disease.

Tan WC, Bourbeau J, Aaron SD, Zhou G, Maltais F, Hernandez P, Fitzgerald JM, Marciniuk DD, Walker BL, Sin DD.

Am J Respir Crit Care Med. 2018 Mar 1;197(5):670-673. doi: 10.1164/rccm.201706-1154LE. No abstract available.

PMID:
28858570
33.

A Novel Method of Estimating Small Airway Disease Using Inspiratory-to-Expiratory Computed Tomography.

Kirby M, Yin Y, Tschirren J, Tan WC, Leipsic J, Hague CJ, Bourbeau J, Sin DD, Hogg JC, Coxson HO; CanCOLD Collaborative Research Group and the Canadian Respiratory Research Network.

Respiration. 2017;94(4):336-345. doi: 10.1159/000478865. Epub 2017 Aug 23.

PMID:
28848199
34.

GDF11: a fountain of youth for the ageing COPD lung?

Obeidat M, Sin DD.

Thorax. 2017 Oct;72(10):874-875. doi: 10.1136/thoraxjnl-2017-210359. Epub 2017 Aug 11. No abstract available.

PMID:
28802278
35.

Concern of underdiagnosing asthma-COPD overlap syndrome if age limit of 40 years for asthma is used.

Sin DD, Leung JM, Wechsler ME.

Eur Respir J. 2017 Aug 3;50(2). pii: 1701120. doi: 10.1183/13993003.01120-2017. Print 2017 Aug. No abstract available.

36.

Excess economic burden of comorbidities in COPD: a 15-year population-based study.

Chen W, FitzGerald JM, Sin DD, Sadatsafavi M; Canadian Respiratory Research Network.

Eur Respir J. 2017 Jul 27;50(1). pii: 1700393. doi: 10.1183/13993003.00393-2017. Print 2017 Jul.

PMID:
28751416
37.

Response.

Ra SW, Sin DD.

Chest. 2017 Jul;152(1):221-222. doi: 10.1016/j.chest.2017.04.158. No abstract available.

PMID:
28693774
38.

Erratum to "Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary" [Arch Bronconeumol. 2017;53:128-49].

Vogelmeier CF, Criner GJ, Martínez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DMG, Varela MVL, Nishimura M, Roche N, Rodríguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agustí A.

Arch Bronconeumol. 2017 Jul;53(7):411-412. doi: 10.1016/j.arbres.2017.06.001. English, Spanish. No abstract available.

39.

American Thoracic Society/National Heart, Lung, and Blood Institute Asthma-Chronic Obstructive Pulmonary Disease Overlap Workshop Report.

Woodruff PG, van den Berge M, Boucher RC, Brightling C, Burchard EG, Christenson SA, Han MK, Holtzman MJ, Kraft M, Lynch DA, Martinez FD, Reddel HK, Sin DD, Washko GR, Wenzel SE, Punturieri A, Freemer MM, Wise RA.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):375-381. doi: 10.1164/rccm.201705-0973WS.

PMID:
28636425
40.

Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori.

Ra SW, Sze MA, Lee EC, Tam S, Oh Y, Fishbane N, Criner GJ, Woodruff PG, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Aaron SD, Reed RM, Man SFP, Sin DD; Canadian Respiratory Research Network.

Respir Res. 2017 May 30;18(1):109. doi: 10.1186/s12931-017-0594-x.

41.

The Cost-Effectiveness of High-Risk Lung Cancer Screening and Drivers of Program Efficiency.

Cressman S, Peacock SJ, Tammemägi MC, Evans WK, Leighl NB, Goffin JR, Tremblay A, Liu G, Manos D, MacEachern P, Bhatia R, Puksa S, Nicholas G, McWilliams A, Mayo JR, Yee J, English JC, Pataky R, McPherson E, Atkar-Khattra S, Johnston MR, Schmidt H, Shepherd FA, Soghrati K, Amjadi K, Burrowes P, Couture C, Sekhon HS, Yasufuku K, Goss G, Ionescu DN, Hwang DM, Martel S, Sin DD, Tan WC, Urbanski S, Xu Z, Tsao MS, Lam S.

J Thorac Oncol. 2017 Aug;12(8):1210-1222. doi: 10.1016/j.jtho.2017.04.021. Epub 2017 May 10.

42.

Surfactant protein-D deficiency suppresses systemic inflammation and reduces atherosclerosis in ApoE knockout mice.

Hirano Y, Choi A, Tsuruta M, Jaw JE, Oh Y, Ngan D, Moritani K, Chen YR, Tam S, Li Y, Vasilescu DM, Hogg JC, Francis G, Bernatchez P, Man SP, Sin DD.

Cardiovasc Res. 2017 Aug 1;113(10):1208-1218. doi: 10.1093/cvr/cvx067.

PMID:
28472244
43.

Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease.

Li X, Obeidat M, Zhou G, Leung JM, Tashkin D, Wise R, Connett J, Joubert P, Bossé Y, van den Berge M, Brandsma CA, Nickle DC, Hao K, Paré PD, Sin DD.

EBioMedicine. 2017 May;19:139-145. doi: 10.1016/j.ebiom.2017.04.020. Epub 2017 Apr 12.

44.

Integrative Genomics of Emphysema-Associated Genes Reveals Potential Disease Biomarkers.

Obeidat M, Nie Y, Fishbane N, Li X, Bossé Y, Joubert P, Nickle DC, Hao K, Postma DS, Timens W, Sze MA, Shannon CP, Hollander Z, Ng RT, McManus B, Miller BE, Rennard S, Spira A, Hackett TL, Lam W, Lam S, Faner R, Agusti A, Hogg JC, Sin DD, Paré PD.

Am J Respir Cell Mol Biol. 2017 Oct;57(4):411-418. doi: 10.1165/rcmb.2016-0284OC.

PMID:
28459279
45.

Serum IgG and risk of exacerbations and hospitalizations in chronic obstructive pulmonary disease.

Leitao Filho FS, Won Ra S, Mattman A, Schellenberg RS, Fishbane N, Criner GJ, Woodruff PG, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Leung JM, Man SFP, Aaron SD, Reed RM, Sin DD.

J Allergy Clin Immunol. 2017 Oct;140(4):1164-1167.e6. doi: 10.1016/j.jaci.2017.01.046. Epub 2017 Apr 27. No abstract available.

PMID:
28456620
46.

Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease.

Obeidat M, Nie Y, Chen V, Shannon CP, Andiappan AK, Lee B, Rotzschke O, Castaldi PJ, Hersh CP, Fishbane N, Ng RT, McManus B, Miller BE, Rennard S, Paré PD, Sin DD.

Respir Res. 2017 Apr 24;18(1):72. doi: 10.1186/s12931-017-0558-1.

47.

Impact of a COPD comprehensive case management program on hospital length of stay and readmission rates.

Alshabanat A, Otterstatter MC, Sin DD, Road J, Rempel C, Burns J, van Eeden SF, FitzGerald JM.

Int J Chron Obstruct Pulmon Dis. 2017 Mar 21;12:961-971. doi: 10.2147/COPD.S124385. eCollection 2017.

48.

COPD: Lessons learned, forging a fantastic future.

Sin DD, King GG.

Respirology. 2017 May;22(4):632-633. doi: 10.1111/resp.13031. Epub 2017 Mar 24. No abstract available.

PMID:
28342243
49.

C-reactive protein and N-terminal prohormone brain natriuretic peptide as biomarkers in acute exacerbations of COPD leading to hospitalizations.

Chen YR, Chen V, Hollander Z, Leipsic JA, Hague CJ, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.

PLoS One. 2017 Mar 22;12(3):e0174063. doi: 10.1371/journal.pone.0174063. eCollection 2017.

50.

Should We Screen for Pulmonary Embolism in Severe COPD Exacerbations? Not Just Yet, Primum Non Nocere.

Ra SW, Sin DD.

Chest. 2017 Mar;151(3):523-524. doi: 10.1016/j.chest.2016.09.018. No abstract available.

PMID:
28279268

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