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Items: 22


Influence of Medication-Induced Preconditioning or Remote Ischemic Preconditioning on the Intrinsic Vascular Extracellular RNA/Ribonuclease System in Cardioprotection.

Tolkmitt KJ, Simsekyilmaz S, Schipke J, Mühlfeld C, Preissner KT, Böning A.

Thorac Cardiovasc Surg. 2019 Sep;67(6):494-501. doi: 10.1055/s-0038-1675398. Epub 2018 Nov 16.


Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis.

Vajen T, Koenen RR, Werner I, Staudt M, Projahn D, Curaj A, Sönmez TT, Simsekyilmaz S, Schumacher D, Möllmann J, Hackeng TM, Hundelshausen PV, Weber C, Liehn EA.

Sci Rep. 2018 Jul 13;8(1):10647. doi: 10.1038/s41598-018-29026-0.


In vivo Molecular Imaging of Glutamate Carboxypeptidase II Expression in Re-endothelialisation after Percutaneous Balloon Denudation in a Rat Model.

Endepols H, Mottaghy FM, Simsekyilmaz S, Bucerius J, Vogt F, Winz O, Richarz R, Krapf P, Neumaier B, Zlatopolskiy BD, Morgenroth A.

Sci Rep. 2018 May 9;8(1):7411. doi: 10.1038/s41598-018-25863-1.


Effects of 6-months' Exercise on Cardiac Function, Structure and Metabolism in Female Hypertensive Rats-The Decisive Role of Lysyl Oxidase and Collagen III.

Schreckenberg R, Horn AM, da Costa Rebelo RM, Simsekyilmaz S, Niemann B, Li L, Rohrbach S, Schlüter KD.

Front Physiol. 2017 Aug 3;8:556. doi: 10.3389/fphys.2017.00556. eCollection 2017.


Cardiomyocyte Hypertrophy in Arrhythmogenic Cardiomyopathy.

Gerçek M, Gerçek M, Kant S, Simsekyilmaz S, Kassner A, Milting H, Liehn EA, Leube RE, Krusche CA.

Am J Pathol. 2017 Apr;187(4):752-766. doi: 10.1016/j.ajpath.2016.12.018. Epub 2017 Feb 7.


Targeting In-Stent-Stenosis with RGD- and CXCL1-Coated Mini-Stents in Mice.

Simsekyilmaz S, Liehn EA, Weinandy S, Schreiber F, Megens RT, Theelen W, Smeets R, Jockenhövel S, Gries T, Möller M, Klee D, Weber C, Zernecke A.

PLoS One. 2016 May 18;11(5):e0155829. doi: 10.1371/journal.pone.0155829. eCollection 2016.


AAL exacerbates pro-inflammatory response in macrophages by regulating Mincle/Syk/Card9 signaling along with the Nlrp3 inflammasome assembly.

Zhang Z, He L, Hu S, Wang Y, Lai Q, Yang P, Yu Q, Zhang S, Xiong F, Simsekyilmaz S, Ning Q, Li J, Zhang D, Zhang H, Xiang X, Zhou Z, Sun H, Wang CY.

Am J Transl Res. 2015 Oct 15;7(10):1812-25. eCollection 2015.


Aloperine Protects Mice against Ischemia-Reperfusion (IR)-Induced Renal Injury by Regulating PI3K/AKT/mTOR Signaling and AP-1 Activity.

Hu S, Zhang Y, Zhang M, Guo Y, Yang P, Zhang S, Simsekyilmaz S, Xu JF, Li J, Xiang X, Yu Q, Wang CY.

Mol Med. 2016 Mar;21(1):912-923. doi: 10.2119/molmed.2015.00056. Epub 2015 Nov 3.


Minimal invasive surgical procedure of inducing myocardial infarction in mice.

Curaj A, Simsekyilmaz S, Staudt M, Liehn E.

J Vis Exp. 2015 May 4;(99):e52197. doi: 10.3791/52197.


Progress in interventional cardiology: challenges for the future.

Simsekyilmaz S, Liehn EA, Militaru C, Vogt F.

Thromb Haemost. 2015 Mar;113(3):464-72. doi: 10.1160/TH14-07-0599. Epub 2015 Jan 22. Review.


RNase1 prevents the damaging interplay between extracellular RNA and tumour necrosis factor-α in cardiac ischaemia/reperfusion injury.

Cabrera-Fuentes HA, Ruiz-Meana M, Simsekyilmaz S, Kostin S, Inserte J, Saffarzadeh M, Galuska SP, Vijayan V, Barba I, Barreto G, Fischer S, Lochnit G, Ilinskaya ON, Baumgart-Vogt E, Böning A, Lecour S, Hausenloy DJ, Liehn EA, Garcia-Dorado D, Schlüter KD, Preissner KT.

Thromb Haemost. 2014 Dec;112(6):1110-9. doi: 10.1160/TH14-08-0703. Epub 2014 Oct 30.


Response to letter regarding article "Role of extracellular RNA in atherosclerotic plaque formation in mice".

Simsekyilmaz S, Cabrera-Fuentes HA, Meiler S, Kostin S, Baumer Y, Liehn EA, Weber C, Boisvert WA, Preissner KT, Zernecke A.

Circulation. 2014 Oct 14;130(16):e144-5. doi: 10.1161/CIRCULATIONAHA.114.012346. No abstract available.


Deficiency of endothelial CXCR4 reduces reendothelialization and enhances neointimal hyperplasia after vascular injury in atherosclerosis-prone mice.

Noels H, Zhou B, Tilstam PV, Theelen W, Li X, Pawig L, Schmitz C, Akhtar S, Simsekyilmaz S, Shagdarsuren E, Schober A, Adams RH, Bernhagen J, Liehn EA, Döring Y, Weber C.

Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1209-20. doi: 10.1161/ATVBAHA.113.302878. Epub 2014 Apr 10.


Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction.

Projahn D, Simsekyilmaz S, Singh S, Kanzler I, Kramp BK, Langer M, Burlacu A, Bernhagen J, Klee D, Zernecke A, Hackeng TM, Groll J, Weber C, Liehn EA, Koenen RR.

J Cell Mol Med. 2014 May;18(5):790-800. doi: 10.1111/jcmm.12225. Epub 2014 Feb 6.


Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice.

Tilstam PV, Gijbels MJ, Habbeddine M, Cudejko C, Asare Y, Theelen W, Zhou B, Döring Y, Drechsler M, Pawig L, Simsekyilmaz S, Koenen RR, de Winther MP, Lawrence T, Bernhagen J, Zernecke A, Weber C, Noels H.

PLoS One. 2014 Feb 3;9(2):e87452. doi: 10.1371/journal.pone.0087452. eCollection 2014.


Role of extracellular RNA in atherosclerotic plaque formation in mice.

Simsekyilmaz S, Cabrera-Fuentes HA, Meiler S, Kostin S, Baumer Y, Liehn EA, Weber C, Boisvert WA, Preissner KT, Zernecke A.

Circulation. 2014 Feb 4;129(5):598-606. doi: 10.1161/CIRCULATIONAHA.113.002562. Epub 2013 Nov 7.


Compartmentalized protective and detrimental effects of endogenous macrophage migration-inhibitory factor mediated by CXCR2 in a mouse model of myocardial ischemia/reperfusion.

Liehn EA, Kanzler I, Konschalla S, Kroh A, Simsekyilmaz S, Sönmez TT, Bucala R, Bernhagen J, Weber C.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2180-6. doi: 10.1161/ATVBAHA.113.301633. Epub 2013 Jul 18.


A murine model of stent implantation in the carotid artery for the study of restenosis.

Simsekyilmaz S, Schreiber F, Weinandy S, Gremse F, Sönmez TT, Liehn EA.

J Vis Exp. 2013 May 14;(75):e50233. doi: 10.3791/50233.


CXC chemokine KC fails to induce neutrophil infiltration and neoangiogenesis in a mouse model of myocardial infarction.

Oral H, Kanzler I, Tuchscheerer N, Curaj A, Simsekyilmaz S, Sönmez TT, Radu E, Postea O, Weber C, Schuh A, Liehn EA.

J Mol Cell Cardiol. 2013 Jul;60:1-7. doi: 10.1016/j.yjmcc.2013.04.006. Epub 2013 Apr 15.


Differential roles of angiogenic chemokines in endothelial progenitor cell-induced angiogenesis.

Kanzler I, Tuchscheerer N, Steffens G, Simsekyilmaz S, Konschalla S, Kroh A, Simons D, Asare Y, Schober A, Bucala R, Weber C, Bernhagen J, Liehn EA.

Basic Res Cardiol. 2013 Jan;108(1):310. doi: 10.1007/s00395-012-0310-4. Epub 2012 Nov 9.


Neutrophil-derived cathelicidin protects from neointimal hyperplasia.

Soehnlein O, Wantha S, Simsekyilmaz S, Döring Y, Megens RT, Mause SF, Drechsler M, Smeets R, Weinandy S, Schreiber F, Gries T, Jockenhoevel S, Möller M, Vijayan S, van Zandvoort MA, Agerberth B, Pham CT, Gallo RL, Hackeng TM, Liehn EA, Zernecke A, Klee D, Weber C.

Sci Transl Med. 2011 Oct 5;3(103):103ra98. doi: 10.1126/scitranslmed.3002531.


C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone mice.

Shagdarsuren E, Bidzhekov K, Mause SF, Simsekyilmaz S, Polakowski T, Hawlisch H, Gessner JE, Zernecke A, Weber C.

Circulation. 2010 Sep 7;122(10):1026-36. doi: 10.1161/CIRCULATIONAHA.110.954370. Epub 2010 Aug 23.


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