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Items: 1 to 50 of 122

1.

Targeting interferon response genes sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell death.

Choi HJ, Lui A, Ogony J, Jan R, Sims PJ, Lewis-Wambi J.

Breast Cancer Res. 2015 Jan 15;17:6. doi: 10.1186/s13058-014-0506-7.

2.

Regulation of the tyrosine phosphorylation of Phospholipid Scramblase 1 in mast cells that are stimulated through the high-affinity IgE receptor.

Kassas A, Moura IC, Yamashita Y, Scheffel J, Guérin-Marchand C, Blank U, Sims PJ, Wiedmer T, Monteiro RC, Rivera J, Charles N, Benhamou M.

PLoS One. 2014 Oct 7;9(10):e109800. doi: 10.1371/journal.pone.0109800. eCollection 2014.

3.

Pediatric psychopharmacology and local anesthesia: potential adverse drug reactions with vasoconstrictor use in dental practice.

Waits J, Cretton-Scott E, Childers NK, Sims PJ.

Pediatr Dent. 2014 Jan-Feb;36(1):18-23. Review.

PMID:
24717703
4.

Phospholipid Scramblase 1, an interferon-regulated gene located at 3q23, is regulated by SnoN/SkiL in ovarian cancer cells.

Kodigepalli KM, Anur P, Spellman P, Sims PJ, Nanjundan M.

Mol Cancer. 2013 Apr 26;12:32. doi: 10.1186/1476-4598-12-32.

5.

Laboratory diagnostic oversight committees and the profession of laboratory medicine.

Jackson BR, Krasowski MD, Sims PJ.

Am J Clin Pathol. 2013 Mar;139(3):273-4. doi: 10.1309/AJCPYK7EKWDCBTJC. No abstract available.

PMID:
23429362
6.

Phospholipid scramblase-1-induced lipid reorganization regulates compensatory endocytosis in neuroendocrine cells.

Ory S, Ceridono M, Momboisse F, Houy S, Chasserot-Golaz S, Heintz D, Calco V, Haeberlé AM, Espinoza FA, Sims PJ, Bailly Y, Bader MF, Gasman S.

J Neurosci. 2013 Feb 20;33(8):3545-56. doi: 10.1523/JNEUROSCI.3654-12.2013.

7.

Review and recommendations for the prevention, management, and treatment of postoperative and postdischarge nausea and vomiting.

Cruthirds D, Sims PJ, Louis PJ.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 May;115(5):601-11. doi: 10.1016/j.oooo.2012.09.088. Epub 2013 Jan 10. Review.

PMID:
23313231
8.

Identification of key regulatory pathways of myeloid differentiation using an mESC-based karyotypically normal cell model.

Li D, Yang H, Nan H, Liu P, Pang S, Zhao Q, Karni R, Kamps MP, Xu Y, Zhou J, Wiedmer T, Sims PJ, Wang F.

Blood. 2012 Dec 6;120(24):4712-9. doi: 10.1182/blood-2012-03-414979. Epub 2012 Oct 18.

9.

Phosphatidylserine externalization and membrane blebbing are involved in the nonclassical export of FGF1.

Kirov A, Al-Hashimi H, Solomon P, Mazur C, Thorpe PE, Sims PJ, Tarantini F, Kumar TK, Prudovsky I.

J Cell Biochem. 2012 Mar;113(3):956-66. doi: 10.1002/jcb.23425.

10.

A minimal nuclear localization signal (NLS) in human phospholipid scramblase 4 that binds only the minor NLS-binding site of importin alpha1.

Lott K, Bhardwaj A, Sims PJ, Cingolani G.

J Biol Chem. 2011 Aug 12;286(32):28160-9. doi: 10.1074/jbc.M111.228007. Epub 2011 Jun 20.

11.

Nuclear phospholipid scramblase 1 prolongs the mitotic expansion of granulocyte precursors during G-CSF-induced granulopoiesis.

Chen CW, Sowden M, Zhao Q, Wiedmer T, Sims PJ.

J Leukoc Biol. 2011 Aug;90(2):221-33. doi: 10.1189/jlb.0111006. Epub 2011 Mar 29.

12.

Calcium-dependent phospholipid scrambling by TMEM16F.

Suzuki J, Umeda M, Sims PJ, Nagata S.

Nature. 2010 Dec 9;468(7325):834-8. doi: 10.1038/nature09583. Epub 2010 Nov 24.

13.

Phospholipid scramblases and Tubby-like proteins belong to a new superfamily of membrane tethered transcription factors.

Bateman A, Finn RD, Sims PJ, Wiedmer T, Biegert A, Söding J.

Bioinformatics. 2009 Jan 15;25(2):159-62. doi: 10.1093/bioinformatics/btn595. Epub 2008 Nov 13.

14.

Expression of the phospholipid scramblase (PLSCR) gene family during the acute phase response.

Lu B, Sims PJ, Wiedmer T, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR.

Biochim Biophys Acta. 2007 Sep;1771(9):1177-85. Epub 2007 May 26.

PMID:
17590392
15.

Drug interactions important for periodontal therapy.

Sims PJ, Sims KM.

Periodontol 2000. 2007;44:15-28. Review. No abstract available.

PMID:
17474923
16.

Mobilization of pro-inflammatory lipids in obese Plscr3-deficient mice.

Mutch DM, O'Maille G, Wikoff WR, Wiedmer T, Sims PJ, Siuzdak G.

Genome Biol. 2007;8(3):R38.

17.

Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells.

Huang Y, Zhao Q, Zhou CX, Gu ZM, Li D, Xu HZ, Wiedmer T, Sims PJ, Zhao KW, Chen GQ.

Oncogene. 2006 Oct 26;25(50):6618-27. Epub 2006 May 15. Erratum in: Oncogene. 2006 Nov 16;25(54):7224. Wiedmer, T [added].

PMID:
16702944
18.
19.

Interferon-alpha-induced expression of phospholipid scramblase 1 through STAT1 requires the sequential activation of protein kinase Cdelta and JNK.

Zhao KW, Li D, Zhao Q, Huang Y, Silverman RH, Sims PJ, Chen GQ.

J Biol Chem. 2005 Dec 30;280(52):42707-14. Epub 2005 Oct 28.

20.

Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression.

Zhou Q, Ben-Efraim I, Bigcas JL, Junqueira D, Wiedmer T, Sims PJ.

J Biol Chem. 2005 Oct 14;280(41):35062-8. Epub 2005 Aug 9.

21.

Phospholipid scramblase 1 contains a nonclassical nuclear localization signal with unique binding site in importin alpha.

Chen MH, Ben-Efraim I, Mitrousis G, Walker-Kopp N, Sims PJ, Cingolani G.

J Biol Chem. 2005 Mar 18;280(11):10599-606. Epub 2004 Dec 17.

22.

Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin.

Giddings KS, Zhao J, Sims PJ, Tweten RK.

Nat Struct Mol Biol. 2004 Dec;11(12):1173-8. Epub 2004 Nov 14.

PMID:
15543155
23.

Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3).

Wiedmer T, Zhao J, Li L, Zhou Q, Hevener A, Olefsky JM, Curtiss LK, Sims PJ.

Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13296-301. Epub 2004 Aug 24.

24.

Phospholipid scramblase 1 potentiates the antiviral activity of interferon.

Dong B, Zhou Q, Zhao J, Zhou A, Harty RN, Bose S, Banerjee A, Slee R, Guenther J, Williams BR, Wiedmer T, Sims PJ, Silverman RH.

J Virol. 2004 Sep;78(17):8983-93.

25.

Protein kinase Cdelta mediates retinoic acid and phorbol myristate acetate-induced phospholipid scramblase 1 gene expression: its role in leukemic cell differentiation.

Zhao KW, Li X, Zhao Q, Huang Y, Li D, Peng ZG, Shen WZ, Zhao J, Zhou Q, Chen Z, Sims PJ, Wiedmer T, Chen GQ.

Blood. 2004 Dec 1;104(12):3731-8. Epub 2004 Aug 12.

26.

Phospholipid scramblase 1 is imported into the nucleus by a receptor-mediated pathway and interacts with DNA.

Ben-Efraim I, Zhou Q, Wiedmer T, Gerace L, Sims PJ.

Biochemistry. 2004 Mar 30;43(12):3518-26.

PMID:
15035622
27.

Plasma membrane phospholipid scramblase 1 promotes EGF-dependent activation of c-Src through the epidermal growth factor receptor.

Nanjundan M, Sun J, Zhao J, Zhou Q, Sims PJ, Wiedmer T.

J Biol Chem. 2003 Sep 26;278(39):37413-8. Epub 2003 Jul 18.

28.

Caspase-independent exposure of aminophospholipids and tyrosine phosphorylation in bicarbonate responsive human sperm cells.

de Vries KJ, Wiedmer T, Sims PJ, Gadella BM.

Biol Reprod. 2003 Jun;68(6):2122-34. Epub 2003 Jan 22.

PMID:
12606386
29.

Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE)).

Kametaka S, Shibata M, Moroe K, Kanamori S, Ohsawa Y, Waguri S, Sims PJ, Emoto K, Umeda M, Uchiyama Y.

J Biol Chem. 2003 Apr 25;278(17):15239-45. Epub 2003 Feb 13.

30.

Palmitoylation of phospholipid scramblase 1 controls its distribution between nucleus and plasma membrane.

Wiedmer T, Zhao J, Nanjundan M, Sims PJ.

Biochemistry. 2003 Feb 11;42(5):1227-33.

PMID:
12564925
31.
32.

Plasma membrane phospholipid scramblase 1 is enriched in lipid rafts and interacts with the epidermal growth factor receptor.

Sun J, Nanjundan M, Pike LJ, Wiedmer T, Sims PJ.

Biochemistry. 2002 May 21;41(20):6338-45.

PMID:
12009895
33.

Suppression of ovarian carcinoma cell growth in vivo by the interferon-inducible plasma membrane protein, phospholipid scramblase 1.

Silverman RH, Halloum A, Zhou A, Dong B, Al-Zoghaibi F, Kushner D, Zhou Q, Zhao J, Wiedmer T, Sims PJ.

Cancer Res. 2002 Jan 15;62(2):397-402.

34.

Unraveling the mysteries of phospholipid scrambling.

Sims PJ, Wiedmer T.

Thromb Haemost. 2001 Jul;86(1):266-75. Review.

PMID:
11487015
35.

c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1.

Sun J, Zhao J, Schwartz MA, Wang JY, Wiedmer T, Sims PJ.

J Biol Chem. 2001 Aug 3;276(31):28984-90. Epub 2001 Jun 4.

36.

Transcriptional control of the human plasma membrane phospholipid scramblase 1 gene is mediated by interferon-alpha.

Zhou Q, Zhao J, Al-Zoghaibi F, Zhou A, Wiedmer T, Silverman RH, Sims PJ.

Blood. 2000 Apr 15;95(8):2593-9.

37.

Identification of three new members of the phospholipid scramblase gene family.

Wiedmer T, Zhou Q, Kwoh DY, Sims PJ.

Biochim Biophys Acta. 2000 Jul 31;1467(1):244-53.

38.

Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology.

Tepper AD, Ruurs P, Wiedmer T, Sims PJ, Borst J, van Blitterswijk WJ.

J Cell Biol. 2000 Jul 10;150(1):155-64.

39.

Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression.

Fadeel B, Gleiss B, Högstrand K, Chandra J, Wiedmer T, Sims PJ, Henter JI, Orrenius S, Samali A.

Biochem Biophys Res Commun. 1999 Dec 20;266(2):504-11.

PMID:
10600532
40.
41.

Mechanisms by which elevated intracellular calcium induces S49 cell membranes to become susceptible to the action of secretory phospholipase A2.

Wilson HA, Waldrip JB, Nielson KH, Judd AM, Han SK, Cho W, Sims PJ, Bell JD.

J Biol Chem. 1999 Apr 23;274(17):11494-504.

42.

Change in conformation of plasma membrane phospholipid scramblase induced by occupancy of its Ca2+ binding site.

Stout JG, Zhou Q, Wiedmer T, Sims PJ.

Biochemistry. 1998 Oct 20;37(42):14860-6.

PMID:
9778361
44.

Tramadol-warfarin interaction.

Sabbe JR, Sims PJ, Sims MH.

Pharmacotherapy. 1998 Jul-Aug;18(4):871-3.

PMID:
9692666
45.
46.
47.
49.
50.

Production and characterization of a mutant cell line defective in aminophospholipid translocase.

Zhao J, Sims PJ, Wiedmer T.

Biochim Biophys Acta. 1997 Jun 5;1357(1):57-64.

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