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Items: 29


Mixed-species RNA-seq for elucidation of non-cell-autonomous control of gene transcription.

Qiu J, Dando O, Baxter PS, Hasel P, Heron S, Simpson TI, Hardingham GE.

Nat Protoc. 2018 Oct;13(10):2176-2199. doi: 10.1038/s41596-018-0029-2.


Author Correction: Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism.

Hasel P, Dando O, Jiwaji Z, Baxter P, Todd AC, Heron S, Márkus NM, McQueen J, Hampton DW, Torvell M, Tiwari SS, McKay S, Eraso-Pichot A, Zorzano A, Masgrau R, Galea E, Chandran S, Wyllie DJA, Simpson TI, Hardingham GE.

Nat Commun. 2018 Feb 6;9:16176. doi: 10.1038/ncomms16176.


Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism.

Hasel P, Dando O, Jiwaji Z, Baxter P, Todd AC, Heron S, Márkus NM, McQueen J, Hampton DW, Torvell M, Tiwari SS, McKay S, Eraso-Pichot A, Zorzano A, Masgrau R, Galea E, Chandran S, Wyllie DJA, Simpson TI, Hardingham GE.

Nat Commun. 2017 May 2;8:15132. doi: 10.1038/ncomms15132. Erratum in: Nat Commun. 2018 Feb 06;9:16176.


Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons.

Qiu J, McQueen J, Bilican B, Dando O, Magnani D, Punovuori K, Selvaraj BT, Livesey M, Haghi G, Heron S, Burr K, Patani R, Rajan R, Sheppard O, Kind PC, Simpson TI, Tybulewicz VL, Wyllie DJ, Fisher EM, Lowell S, Chandran S, Hardingham GE.

Elife. 2016 Oct 1;5. pii: e20337. doi: 10.7554/eLife.20337.


Analysis of compound heterozygotes reveals that the mouse floxed Pax6 (tm1Ued) allele produces abnormal eye phenotypes.

Dorà NJ, Crookshanks AJ, Leung KK, Simpson TI, Mason JO, Price DJ, West JD.

Transgenic Res. 2016 Oct;25(5):679-92. doi: 10.1007/s11248-016-9962-4. Epub 2016 May 30.


Fluid consumption and taste novelty determines transcription temporal dynamics in the gustatory cortex.

Inberg S, Jacob E, Elkobi A, Edry E, Rappaport A, Simpson TI, Armstrong JD, Shomron N, Pasmanik-Chor M, Rosenblum K.

Mol Brain. 2016 Feb 9;9:13. doi: 10.1186/s13041-016-0188-4.


Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ Signaling.

Márkus NM, Hasel P, Qiu J, Bell KF, Heron S, Kind PC, Dando O, Simpson TI, Hardingham GE.

PLoS One. 2016 Feb 1;11(2):e0148164. doi: 10.1371/journal.pone.0148164. eCollection 2016.


Network analyses reveal novel aspects of ALS pathogenesis.

Sanhueza M, Chai A, Smith C, McCray BA, Simpson TI, Taylor JP, Pennetta G.

PLoS Genet. 2015 Mar 31;11(3):e1005107. doi: 10.1371/journal.pgen.1005107. eCollection 2015 Mar.


The reduced kinome of Ostreococcus tauri: core eukaryotic signalling components in a tractable model species.

Hindle MM, Martin SF, Noordally ZB, van Ooijen G, Barrios-Llerena ME, Simpson TI, Le Bihan T, Millar AJ.

BMC Genomics. 2014 Aug 2;15:640. doi: 10.1186/1471-2164-15-640.


NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo.

Pai B, Siripornmongcolchai T, Berentsen B, Pakzad A, Vieuille C, Pallesen S, Pajak M, Simpson TI, Armstrong JD, Wibrand K, Bramham CR.

Front Cell Neurosci. 2014 Jan 13;7:285. doi: 10.3389/fncel.2013.00285. eCollection 2014 Jan 13.


Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb.

Mi D, Carr CB, Georgala PA, Huang YT, Manuel MN, Jeanes E, Niisato E, Sansom SN, Livesey FJ, Theil T, Hasenpusch-Theil K, Simpson TI, Mason JO, Price DJ.

Neuron. 2013 Apr 24;78(2):269-84. doi: 10.1016/j.neuron.2013.02.012.


Consolidation and translation regulation.

Gal-Ben-Ari S, Kenney JW, Ounalla-Saad H, Taha E, David O, Levitan D, Gildish I, Panja D, Pai B, Wibrand K, Simpson TI, Proud CG, Bramham CR, Armstrong JD, Rosenblum K.

Learn Mem. 2012 Aug 16;19(9):410-22. doi: 10.1101/lm.026849.112. Review.


Bio::Homology::InterologWalk--a Perl module to build putative protein-protein interaction networks through interolog mapping.

Gallone G, Simpson TI, Armstrong JD, Jarman AP.

BMC Bioinformatics. 2011 Jul 18;12:289. doi: 10.1186/1471-2105-12-289.


Linking specification to differentiation: From proneural genes to the regulation of ciliogenesis.

zur Lage PI, Simpson TI, Jarman A.

Fly (Austin). 2011 Oct-Dec;5(4):322-6. doi: 10.4161/fly.5.4.16159. Epub 2011 May 11.


The gene regulatory cascade linking proneural specification with differentiation in Drosophila sensory neurons.

Cachero S, Simpson TI, Zur Lage PI, Ma L, Newton FG, Holohan EE, Armstrong JD, Jarman AP.

PLoS Biol. 2011 Jan 4;9(1):e1000568. doi: 10.1371/journal.pbio.1000568.


Merged consensus clustering to assess and improve class discovery with microarray data.

Simpson TI, Armstrong JD, Jarman AP.

BMC Bioinformatics. 2010 Dec 3;11:590. doi: 10.1186/1471-2105-11-590.


Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice.

Simpson TI, Pratt T, Mason JO, Price DJ.

Neural Dev. 2009 Jun 5;4:19. doi: 10.1186/1749-8104-4-19.


Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization.

Manuel M, Georgala PA, Carr CB, Chanas S, Kleinjan DA, Martynoga B, Mason JO, Molinek M, Pinson J, Pratt T, Quinn JC, Simpson TI, Tyas DA, van Heyningen V, West JD, Price DJ.

Development. 2007 Feb;134(3):545-55. Epub 2007 Jan 3.


Penetrance of eye defects in mice heterozygous for mutation of Gli3 is enhanced by heterozygous mutation of Pax6.

Zaki PA, Collinson JM, Toraiwa J, Simpson TI, Price DJ, Quinn JC.

BMC Dev Biol. 2006 Oct 9;6:46.


Long-range downstream enhancers are essential for Pax6 expression.

Kleinjan DA, Seawright A, Mella S, Carr CB, Tyas DA, Simpson TI, Mason JO, Price DJ, van Heyningen V.

Dev Biol. 2006 Nov 15;299(2):563-81. Epub 2006 Aug 30.


Functional conservation of Pax6 regulatory elements in humans and mice demonstrated with a novel transgenic reporter mouse.

Tyas DA, Simpson TI, Carr CB, Kleinjan DA, van Heyningen V, Mason JO, Price DJ.

BMC Dev Biol. 2006 May 4;6:21.


Regulation of the Pax6 : Pax6(5a) mRNA ratio in the developing mammalian brain.

Pinson J, Mason JO, Simpson TI, Price DJ.

BMC Dev Biol. 2005 Jul 19;5:13.


The motility of glioblastoma tumour cells is modulated by intracellular cofilin expression in a concentration-dependent manner.

Yap CT, Simpson TI, Pratt T, Price DJ, Maciver SK.

Cell Motil Cytoskeleton. 2005 Mar;60(3):153-65.


The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse.

Pratt T, Tian NM, Simpson TI, Mason JO, Price DJ.

Development. 2004 Aug;131(15):3773-84. Epub 2004 Jul 7.


Identifying GFP-transgenic animals by flashlight.

Tyas DA, Pratt T, Simpson TI, Mason JO, Price DJ.

Biotechniques. 2003 Mar;34(3):474-6. No abstract available.


Pax6; a pleiotropic player in development.

Simpson TI, Price DJ.

Bioessays. 2002 Nov;24(11):1041-51. Review.


Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.

Pratt T, Quinn JC, Simpson TI, West JD, Mason JO, Price DJ.

J Neurosci. 2002 Oct 1;22(19):8523-31.


Routine intraoperative laparoscopic cholangiography.

Stuart SA, Simpson TI, Alvord LA, Williams MD.

Am J Surg. 1998 Dec;176(6):632-7.


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