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FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism.

Hill CM, Laeger T, Dehner M, Albarado DC, Clarke B, Wanders D, Burke SJ, Collier JJ, Qualls-Creekmore E, Solon-Biet SM, Simpson SJ, Berthoud HR, Münzberg H, Morrison CD.

Cell Rep. 2019 Jun 4;27(10):2934-2947.e3. doi: 10.1016/j.celrep.2019.05.022.


Aging, lifestyle and dementia.

Wahl D, Solon-Biet SM, Cogger VC, Fontana L, Simpson SJ, Le Couteur DG, Ribeiro RV.

Neurobiol Dis. 2019 May 25;130:104481. doi: 10.1016/j.nbd.2019.104481. [Epub ahead of print] Review.


Preterm birth: Born too soon for the developing airway epithelium?

Looi K, Evans DJ, Garratt LW, Ang S, Hillas JK, Kicic A, Simpson SJ.

Paediatr Respir Rev. 2018 Dec 1. pii: S1526-0542(18)30135-0. doi: 10.1016/j.prrv.2018.11.003. [Epub ahead of print] Review.


Dietary macronutrient content, age-specific mortality and lifespan.

Senior AM, Solon-Biet SM, Cogger VC, Le Couteur DG, Nakagawa S, Raubenheimer D, Simpson SJ.

Proc Biol Sci. 2019 May 15;286(1902):20190393. doi: 10.1098/rspb.2019.0393.


Macronutrient intakes and the lifespan-fecundity trade-off: a geometric framework agent-based model.

Hosking CJ, Raubenheimer D, Charleston MA, Simpson SJ, Senior AM.

J R Soc Interface. 2019 Feb 28;16(151):20180733. doi: 10.1098/rsif.2018.0733.


Prospective Associations Between Dietary Antioxidant Intake and Frailty in Older Australian Men: The Concord Health and Ageing in Men Project.

Das A, Cumming RG, Naganathan V, Blyth F, Ribeiro RV, Le Couteur DG, Handelsman DJ, Waite LM, Simpson SJ, Hirani V.

J Gerontol A Biol Sci Med Sci. 2019 Apr 6. pii: glz054. doi: 10.1093/gerona/glz054. [Epub ahead of print]


Diet modulates the relationship between immune gene expression and functional immune responses.

Cotter SC, Reavey CE, Tummala Y, Randall JL, Holdbrook R, Ponton F, Simpson SJ, Smith JA, Wilson K.

Insect Biochem Mol Biol. 2019 Jun;109:128-141. doi: 10.1016/j.ibmb.2019.04.009. Epub 2019 Apr 5.


Ingestion of resistant starch by mice markedly increases microbiome-derived metabolites.

Koay YC, Wali JA, Luk AWS, Macia L, Cogger VC, Pulpitel TJ, Wahl D, Solon-Biet SM, Holmes A, Simpson SJ, O'Sullivan JF.

FASEB J. 2019 Mar 29:fj201900177R. doi: 10.1096/fj.201900177R. [Epub ahead of print]


Identifying pediatric lung disease: A comparison of forced oscillation technique outcomes.

Evans DJ, Schultz A, Verheggen M, Hall GL, Simpson SJ.

Pediatr Pulmonol. 2019 Jun;54(6):751-758. doi: 10.1002/ppul.24286. Epub 2019 Mar 18.


Sucrose and starch intake contribute to reduced alveolar bone height in a rodent model of naturally occurring periodontitis.

Morimoto J, Senior A, Ruiz K, Wali JA, Pulpitel T, Solon-Biet SM, Cogger VC, Raubenheimer D, Le Couteur DG, Simpson SJ, Eberhard J.

PLoS One. 2019 Mar 13;14(3):e0212796. doi: 10.1371/journal.pone.0212796. eCollection 2019.


Bronchopulmonary dysplasia: Rationale for a pathophysiological rather than treatment based approach to diagnosis.

Stoecklin B, Simpson SJ, Pillow JJ.

Paediatr Respir Rev. 2018 Dec 19. pii: S1526-0542(18)30166-0. doi: 10.1016/j.prrv.2018.12.002. [Epub ahead of print] Review.


Anoxia tolerance of the adult Australian Plague Locust (Chortoicetes terminifera).

Robertson RM, Cease AJ, Simpson SJ.

Comp Biochem Physiol A Mol Integr Physiol. 2019 Mar;229:81-92. doi: 10.1016/j.cbpa.2018.12.005. Epub 2018 Dec 18.


Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice.

Wahl D, Solon-Biet SM, Wang QP, Wali JA, Pulpitel T, Clark X, Raubenheimer D, Senior AM, Sinclair DA, Cooney GJ, de Cabo R, Cogger VC, Simpson SJ, Le Couteur DG.

Cell Rep. 2018 Nov 20;25(8):2234-2243.e6. doi: 10.1016/j.celrep.2018.10.070.


Hepatitis B Vaccination Induces Mucosal Antibody Responses in the Female Genital Tract, Indicating Potential Mechanisms of Protection Against Infection.

Simpson SJ, Wiggins R, Fox JM, Mthethwa J, Cai C, Lacey CJN.

Sex Transm Dis. 2019 May;46(5):e53-e56. doi: 10.1097/OLQ.0000000000000949.


Increased prevalence of expiratory flow limitation during exercise in children with bronchopulmonary dysplasia.

O'Dea CA, Logie K, Maiorana A, Wilson AC, Pillow JJ, Banton GL, Simpson SJ, Hall GL.

ERJ Open Res. 2018 Oct 8;4(4). pii: 00048-2018. doi: 10.1183/23120541.00048-2018. eCollection 2018 Oct.


90th Anniversary Commentary: Caloric Restriction Effects on Aging.

Le Couteur DG, Simpson SJ.

J Nutr. 2018 Oct 1;148(10):1656-1659. doi: 10.1093/jn/nxy146. No abstract available.


Insulin-Like Peptides Regulate Feeding Preference and Metabolism in Drosophila.

Semaniuk UV, Gospodaryov DV, Feden'ko KM, Yurkevych IS, Vaiserman AM, Storey KB, Simpson SJ, Lushchak O.

Front Physiol. 2018 Aug 24;9:1083. doi: 10.3389/fphys.2018.01083. eCollection 2018.


Lung function trajectories throughout childhood in survivors of very preterm birth: a longitudinal cohort study.

Simpson SJ, Turkovic L, Wilson AC, Verheggen M, Logie KM, Pillow JJ, Hall GL.

Lancet Child Adolesc Health. 2018 May;2(5):350-359. doi: 10.1016/S2352-4642(18)30064-6. Epub 2018 Mar 22.


The impact of respiratory viruses on lung health after preterm birth.

Townsi N, Laing IA, Hall GL, Simpson SJ.

Eur Clin Respir J. 2018 Aug 1;5(1):1487214. doi: 10.1080/20018525.2018.1487214. eCollection 2018. Review.


The Relationship Between Dietary Macronutrients and Hepatic Telomere Length in Aging Mice.

Gokarn R, Solon-Biet S, Youngson NA, Wahl D, Cogger VC, McMahon AC, Cooney GJ, Ballard JWO, Raubenheimer D, Morris MJ, Simpson SJ, Le Couteur DG.

J Gerontol A Biol Sci Med Sci. 2018 Mar 14;73(4):446-449. doi: 10.1093/gerona/glx186.


Nutritional ecology and foraging theory.

Raubenheimer D, Simpson SJ.

Curr Opin Insect Sci. 2018 Jun;27:38-45. doi: 10.1016/j.cois.2018.02.002. Epub 2018 Feb 8. Review.


Future directions of resveratrol research.

Wahl D, Bernier M, Simpson SJ, de Cabo R, Le Couteur DG.

Nutr Healthy Aging. 2018 Jun 15;4(4):287-290. doi: 10.3233/NHA-170035. Review.


Persistent and progressive long-term lung disease in survivors of preterm birth.

Urs R, Kotecha S, Hall GL, Simpson SJ.

Paediatr Respir Rev. 2018 Sep;28:87-94. doi: 10.1016/j.prrv.2018.04.001. Epub 2018 Apr 13. Review.


Composite Mesenchymal Stromal Cell Islets: Implications for Transplantation via the Clinically Preferred Intraportal Route.

Rackham CL, Dhadda PK, Simpson SJS, Godazgar M, King AJF, Jones PM.

Transplant Direct. 2018 Mar 19;4(4):e354. doi: 10.1097/TXD.0000000000000778. eCollection 2018 Apr. No abstract available.


Long-term Dietary Macronutrients and Hepatic Gene Expression in Aging Mice.

Gokarn R, Solon-Biet SM, Cogger VC, Cooney GJ, Wahl D, McMahon AC, Mitchell JR, Mitchell SJ, Hine C, de Cabo R, Raubenheimer D, Simpson SJ, Le Couteur DG.

J Gerontol A Biol Sci Med Sci. 2018 Nov 10;73(12):1618-1625. doi: 10.1093/gerona/gly065.


Dietary protein supplementation and its consequences for intake, digestion, and physical activity of a carnivorous marsupial, Sminthopsis crassicaudata.

Yuan L, Wilder S, Raubenheimer D, Simpson SJ, Shaw M, McAllan BM.

Ecol Evol. 2018 Mar 5;8(7):3636-3647. doi: 10.1002/ece3.3843. eCollection 2018 Apr.


Epigenetics and developmental plasticity in orthopteroid insects.

Lo N, Simpson SJ, Sword GA.

Curr Opin Insect Sci. 2018 Feb;25:25-34. doi: 10.1016/j.cois.2017.11.003. Epub 2017 Nov 10. Review.


Skew in ovarian activation depends on domicile size in phyllode-glueing thrips.

Gilbert JDJ, Wells A, Simpson SJ.

Sci Rep. 2018 Feb 26;8(1):3597. doi: 10.1038/s41598-018-21635-z.


The Geometric Framework for Nutrition as a tool in precision medicine.

Simpson SJ, Le Couteur DG, James DE, George J, Gunton JE, Solon-Biet SM, Raubenheimer D.

Nutr Healthy Aging. 2017 Dec 7;4(3):217-226. doi: 10.3233/NHA-170027. Review.


Environmental exposure and parental collection does not affect detection or semi-quantitative load assessment of bacteria in nasal swab specimens from children.

Townsi N, Simpson SJ, Sikazwe CT, Chidlow GR, Hall GL, Pillow JJ, Wilson AC, Smith DW, Laing IA.

Infect Dis (Lond). 2018 Jun;50(6):468-471. doi: 10.1080/23744235.2017.1411607. Epub 2017 Dec 13. No abstract available.


Fruit flies may face a nutrient-dependent life-history trade-off between secondary sexual trait quality, survival and developmental rate.

Gray LJ, Simpson SJ, Polak M.

J Insect Physiol. 2018 Jan;104:60-70. doi: 10.1016/j.jinsphys.2017.11.010. Epub 2017 Dec 2.


Intergenerational effects of nutrition on immunity: a systematic review and meta-analysis.

Grueber CE, Gray LJ, Morris KM, Simpson SJ, Senior AM.

Biol Rev Camb Philos Soc. 2018 May;93(2):1108-1124. doi: 10.1111/brv.12387. Epub 2017 Nov 27.


The nutritional geometry of liver disease including non-alcoholic fatty liver disease.

Simpson SJ, Raubenheimer D, Cogger VC, Macia L, Solon-Biet SM, Le Couteur DG, George J.

J Hepatol. 2018 Feb;68(2):316-325. doi: 10.1016/j.jhep.2017.10.005. Epub 2017 Nov 6. Review.


Ultra-processed foods, protein leverage and energy intake in the USA.

Martínez Steele E, Raubenheimer D, Simpson SJ, Baraldi LG, Monteiro CA.

Public Health Nutr. 2018 Jan;21(1):114-124. doi: 10.1017/S1368980017001574. Epub 2017 Oct 16.


Nutritional geometry of paternal effects on embryo mortality.

Polak M, Simmons LW, Benoit JB, Ruohonen K, Simpson SJ, Solon-Biet SM.

Proc Biol Sci. 2017 Oct 11;284(1864). pii: 20171492. doi: 10.1098/rspb.2017.1492.


Targeting the Cohesive Cluster Phenotype in Chordoma via β1 Integrin Increases Ionizing Radiation Efficacy.

Harryman WL, Gard JMC, Pond KW, Simpson SJ, Heppner LH, Hernandez-Cortes D, Little AS, Eschbacher JM, Cress AE.

Neoplasia. 2017 Nov;19(11):919-927. doi: 10.1016/j.neo.2017.08.005. Epub 2017 Sep 24.


Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia.

Wahl D, Coogan SC, Solon-Biet SM, de Cabo R, Haran JB, Raubenheimer D, Cogger VC, Mattson MP, Simpson SJ, Le Couteur DG.

Clin Interv Aging. 2017 Sep 8;12:1419-1428. doi: 10.2147/CIA.S145247. eCollection 2017. Review.


Diet has independent effects on the pace and shape of aging in Drosophila melanogaster.

Ruth Archer C, Basellini U, Hunt J, Simpson SJ, Lee KP, Baudisch A.

Biogerontology. 2018 Feb;19(1):1-12. doi: 10.1007/s10522-017-9729-1. Epub 2017 Sep 15.


Growth performance, nutrient utilisation and carcass composition respond to dietary protein concentrations in broiler chickens but responses are modified by dietary lipid levels.

Liu SY, Selle PH, Raubenheimer D, Gous RM, Chrystal PV, Cadogan DJ, Simpson SJ, Cowieson AJ.

Br J Nutr. 2017 Aug;118(4):250-262. doi: 10.1017/S0007114517002070.


Diet quality and its implications on the cardio-metabolic, physical and general health of older men: the Concord Health and Ageing in Men Project (CHAMP).

Ribeiro RV, Hirani V, Senior AM, Gosby AK, Cumming RG, Blyth FM, Naganathan V, Waite LM, Handelsman DJ, Kendig H, Seibel MJ, Simpson SJ, Stanaway F, Allman-Farinelli M, Le Couteur DG.

Br J Nutr. 2017 Jul;118(2):130-143. doi: 10.1017/S0007114517001738.


Chronic Sucralose or L-Glucose Ingestion Does Not Suppress Food Intake.

Wang QP, Simpson SJ, Herzog H, Neely GG.

Cell Metab. 2017 Aug 1;26(2):279-280. doi: 10.1016/j.cmet.2017.07.002.


Gut Microbiota Modifies Olfactory-Guided Microbial Preferences and Foraging Decisions in Drosophila.

Wong AC, Wang QP, Morimoto J, Senior AM, Lihoreau M, Neely GG, Simpson SJ, Ponton F.

Curr Biol. 2017 Aug 7;27(15):2397-2404.e4. doi: 10.1016/j.cub.2017.07.022. Epub 2017 Jul 27.


Direct and trans-generational effects of male and female gut microbiota in Drosophila melanogaster.

Morimoto J, Simpson SJ, Ponton F.

Biol Lett. 2017 Jul;13(7). pii: 20160966. doi: 10.1098/rsbl.2016.0966.


Collective foraging in spatially complex nutritional environments.

Lihoreau M, Charleston MA, Senior AM, Clissold FJ, Raubenheimer D, Simpson SJ, Buhl J.

Philos Trans R Soc Lond B Biol Sci. 2017 Aug 19;372(1727). pii: 20160238. doi: 10.1098/rstb.2016.0238.


Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan.

Piper MDW, Soultoukis GA, Blanc E, Mesaros A, Herbert SL, Juricic P, He X, Atanassov I, Salmonowicz H, Yang M, Simpson SJ, Ribeiro C, Partridge L.

Cell Metab. 2017 May 2;25(5):1206. doi: 10.1016/j.cmet.2017.04.020. No abstract available.


Dietary restriction increases variability in longevity.

Senior AM, Nakagawa S, Raubenheimer D, Simpson SJ, Noble DW.

Biol Lett. 2017 Mar;13(3). pii: 20170057. doi: 10.1098/rsbl.2017.0057.


Dietary protein, aging and nutritional geometry.

Simpson SJ, Le Couteur DG, Raubenheimer D, Solon-Biet SM, Cooney GJ, Cogger VC, Fontana L.

Ageing Res Rev. 2017 Oct;39:78-86. doi: 10.1016/j.arr.2017.03.001. Epub 2017 Mar 6. Review.


Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan.

Piper MDW, Soultoukis GA, Blanc E, Mesaros A, Herbert SL, Juricic P, He X, Atanassov I, Salmonowicz H, Yang M, Simpson SJ, Ribeiro C, Partridge L.

Cell Metab. 2017 Mar 7;25(3):610-621. doi: 10.1016/j.cmet.2017.02.005. Erratum in: Cell Metab. 2017 May 2;25(5):1206.


Integrative Physiology: At the Crossroads of Nutrition, Microbiota, Animal Physiology, and Human Health.

Leulier F, MacNeil LT, Lee WJ, Rawls JF, Cani PD, Schwarzer M, Zhao L, Simpson SJ.

Cell Metab. 2017 Mar 7;25(3):522-534. doi: 10.1016/j.cmet.2017.02.001. Review.


Effect of posture on lung ventilation distribution and associations with structure in children with cystic fibrosis.

Ramsey KA, McGirr C, Stick SM, Hall GL, Simpson SJ; AREST CF.

J Cyst Fibros. 2017 Nov;16(6):713-718. doi: 10.1016/j.jcf.2017.01.013. Epub 2017 Feb 7.


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