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Items: 1 to 50 of 832

1.

Exercise as a countermeasure for latent viral reactivation during long duration space flight.

Agha NH, Mehta SK, Rooney BV, Laughlin MS, Markofski MM, Pierson DL, Katsanis E, Crucian BE, Simpson RJ.

FASEB J. 2020 Jan 3. doi: 10.1096/fj.201902327R. [Epub ahead of print]

PMID:
31908052
2.

Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome.

Greening DW, Notaras M, Chen M, Xu R, Smith JD, Cheng L, Simpson RJ, Hill AF, van den Buuse M.

Mol Psychiatry. 2019 Dec 10. doi: 10.1038/s41380-019-0617-8. [Epub ahead of print]

PMID:
31822818
3.

Coronary Artery Disease and Atherosclerotic Risk Factors in a Population-Based Study of Sudden Death.

Joodi G, Maradey JA, Bogle B, Mirzaei M, Sadaf MI, Pursell I, Henderson C, Mounsey JP, Simpson RJ Jr.

J Gen Intern Med. 2019 Dec 5. doi: 10.1007/s11606-019-05486-6. [Epub ahead of print]

PMID:
31808130
4.

A case-crossover analysis of the relationship of air pollution with out-of-hospital sudden unexpected death in Wake County, North Carolina (2013-2015).

Rappazzo KM, Joodi G, Hoffman SR, Pursell IW Jr, Mounsey JP, Cascio WE, Simpson RJ Jr.

Sci Total Environ. 2019 Dec 1;694:133744. doi: 10.1016/j.scitotenv.2019.133744. Epub 2019 Aug 2.

PMID:
31756798
5.

Salivary antimicrobial proteins and stress biomarkers are elevated during a 6-month mission to the International Space Station.

Agha NH, Baker FL, Kunz HE, Spielmann G, Mylabathula PL, Rooney BV, Mehta SK, Pierson DL, Laughlin MS, Markofski MM, Crucian BE, Simpson RJ.

J Appl Physiol (1985). 2019 Nov 21. doi: 10.1152/japplphysiol.00560.2019. [Epub ahead of print]

PMID:
31751178
6.

Action Boundary Proximity Effects on Perceptual-Motor Judgments.

Johnson CD, LaGoy AD, Pepping GJ, Eagle SR, Beethe AZ, Bower JL, Alfano CA, Simpson RJ, Connaboy C.

Aerosp Med Hum Perform. 2019 Dec 1;90(12):1000-1008. doi: 10.3357/AMHP.5376.2019.

PMID:
31747996
7.

Specific Immunologic Countermeasure Protocol for Deep-Space Exploration Missions.

Makedonas G, Mehta S, Choukèr A, Simpson RJ, Marshall G, Orange JS, Aunon-Chancellor S, Smith SM, Zwart SR, Stowe RP, Heer M, Ponomarev S, Whitmire A, Frippiat JP, Douglas GL, Krieger SS, Lorenzi H, Buchheim JI, Ginsburg GS, Ott CM, Downs M, Pierson D, Baecker N, Sams C, Crucian B.

Front Immunol. 2019 Oct 11;10:2407. doi: 10.3389/fimmu.2019.02407. eCollection 2019. No abstract available.

8.

Effect of Initiating Cardiac Rehabilitation After Myocardial Infarction on Subsequent Hospitalization in Older Adults.

Bush M, Kucharska-Newton A, Simpson RJ Jr, Fang G, Stürmer T, Brookhart MA.

J Cardiopulm Rehabil Prev. 2019 Oct 4. doi: 10.1097/HCR.0000000000000452. [Epub ahead of print]

PMID:
31592930
9.

Human Endometrial Extracellular Vesicles Functionally Prepare Human Trophectoderm Model for Implantation: Understanding Bidirectional Maternal-Embryo Communication.

Evans J, Rai A, Nguyen HPT, Poh QH, Elglass K, Simpson RJ, Salamonsen LA, Greening DW.

Proteomics. 2019 Dec;19(23):e1800423. doi: 10.1002/pmic.201800423. Epub 2019 Oct 30.

PMID:
31531940
10.

Large-scale network dysfunction in vascular cognitive disorder supports connectional diaschisis in advanced arteriosclerosis.

Meng D, Hosseini AA, Simpson RJ, Welton T, Dineen RA, Auer DP.

Eur J Neurol. 2020 Feb;27(2):352-359. doi: 10.1111/ene.14084. Epub 2019 Oct 25.

PMID:
31505084
11.

LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA.

Izumikawa K, Ishikawa H, Yoshikawa H, Fujiyama S, Watanabe A, Aburatani H, Tachikawa H, Hayano T, Miura Y, Isobe T, Simpson RJ, Li L, Min J, Takahashi N.

Nucleic Acids Res. 2019 Nov 4;47(19):10357-10372. doi: 10.1093/nar/gkz747.

12.

'Working-out' the link between inflammation and brain health.

Simpson RJ.

Brain Behav Immun. 2019 Nov;82:6-7. doi: 10.1016/j.bbi.2019.08.199. Epub 2019 Sep 3. No abstract available.

PMID:
31491489
13.

Renin-Angiotensin-Aldosterone System-based Antihypertensive Agents and the Risk of Colorectal Cancer Among Medicare Beneficiaries.

Htoo PT, Stürmer T, Jonsson-Funk M, Pate V, Simpson RJ Jr, Lund JL.

Epidemiology. 2019 Nov;30(6):867-875. doi: 10.1097/EDE.0000000000001065.

PMID:
31348009
14.

Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques: Meta-Analysis of Individual Patient Data.

Schindler A, Schinner R, Altaf N, Hosseini AA, Simpson RJ, Esposito-Bauer L, Singh N, Kwee RM, Kurosaki Y, Yamagata S, Yoshida K, Miyamoto S, Maggisano R, Moody AR, Poppert H, Kooi ME, Auer DP, Bonati LH, Saam T.

JACC Cardiovasc Imaging. 2019 Jun 8. pii: S1936-878X(19)30437-1. doi: 10.1016/j.jcmg.2019.03.028. [Epub ahead of print]

15.

Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?

Duggal NA, Niemiro G, Harridge SDR, Simpson RJ, Lord JM.

Nat Rev Immunol. 2019 Sep;19(9):563-572. doi: 10.1038/s41577-019-0177-9. Review.

PMID:
31175337
16.

Years of Life and Productivity Loss Because of Adult Sudden Unexpected Death in the United States.

Mirzaei M, Joodi G, Bogle B, Chen S, Simpson RJ Jr.

Med Care. 2019 Jul;57(7):498-502. doi: 10.1097/MLR.0000000000001129.

PMID:
31107395
17.

Quantifying Unmet Need in Statin-Treated Hyperlipidemia Patients and the Potential Benefit of Further LDL-C Reduction Through an EHR-Based Retrospective Cohort Study.

Schleyer T, Hui S, Wang J, Zhang Z, Knapp K, Baker J, Chase M, Boggs R, Simpson RJ Jr.

J Manag Care Spec Pharm. 2019 May;25(5):544-554. doi: 10.18553/jmcp.2019.25.5.544.

18.

Part II: Special Issue on Extracellular Vesicles and Exosomes.

Simpson RJ, Greening DW.

Proteomics. 2019 Apr;19(8):e1900121. doi: 10.1002/pmic.201900121. No abstract available.

PMID:
30990259
19.

Surfaceome of Exosomes Secreted from the Colorectal Cancer Cell Line SW480: Peripheral and Integral Membrane Proteins Analyzed by Proteolysis and TX114.

Xu R, Greening DW, Chen M, Rai A, Ji H, Takahashi N, Simpson RJ.

Proteomics. 2019 Apr;19(8):e1700453. doi: 10.1002/pmic.201700453.

PMID:
30865381
20.

Somatic proteome of Haemonchus contortus.

Wang T, Ma G, Ang CS, Korhonen PK, Xu R, Nie S, Koehler AV, Simpson RJ, Greening DW, Reid GE, Williamson NA, Gasser RB.

Int J Parasitol. 2019 Mar;49(3-4):311-320. doi: 10.1016/j.ijpara.2018.12.003. Epub 2019 Feb 14.

PMID:
30771357
21.

TDP-43 regulates site-specific 2'-O-methylation of U1 and U2 snRNAs via controlling the Cajal body localization of a subset of C/D scaRNAs.

Izumikawa K, Nobe Y, Ishikawa H, Yamauchi Y, Taoka M, Sato K, Nakayama H, Simpson RJ, Isobe T, Takahashi N.

Nucleic Acids Res. 2019 Mar 18;47(5):2487-2505. doi: 10.1093/nar/gkz086.

22.

Factors Underlying Increased Incidence of Sudden Unexpected Death in Rural Counties in North Carolina.

Gan ZSW, Choi W, Lin FC, Tippett R, Joodi G, Pursell I, Simpson RJ Jr.

J Gen Intern Med. 2019 Jun;34(6):815-817. doi: 10.1007/s11606-018-4771-5. No abstract available.

PMID:
30684197
23.

Special Issue on Extracellular Vesicles and Exosomes.

Simpson RJ, Greening DW.

Proteomics. 2019 Jan;19(1-2):e1800434. doi: 10.1002/pmic.201800434. No abstract available.

PMID:
30680945
24.

Intersession Reliability and Within-Session Stability of a Novel Perception-Action Coupling Task.

Connaboy C, Johnson CD, LaGoy AD, Pepping GJ, Simpson RJ, Deng Z, Ma L, Bower JL, Eagle SR, Flanagan SD, Alfano CA.

Aerosp Med Hum Perform. 2019 Feb 1;90(2):77-83. doi: 10.3357/AMHP.5190.2019.

PMID:
30670116
25.

Distinct shed microvesicle and exosome microRNA signatures reveal diagnostic markers for colorectal cancer.

Chen M, Xu R, Rai A, Suwakulsiri W, Izumikawa K, Ishikawa H, Greening DW, Takahashi N, Simpson RJ.

PLoS One. 2019 Jan 4;14(1):e0210003. doi: 10.1371/journal.pone.0210003. eCollection 2019.

26.

Exosomes Derived from Human Primary and Metastatic Colorectal Cancer Cells Contribute to Functional Heterogeneity of Activated Fibroblasts by Reprogramming Their Proteome.

Rai A, Greening DW, Chen M, Xu R, Ji H, Simpson RJ.

Proteomics. 2019 Apr;19(8):e1800148. doi: 10.1002/pmic.201800148. Epub 2019 Jan 31.

PMID:
30582284
27.

Proteomic profiling reveals key cancer progression modulators in shed microvesicles released from isogenic human primary and metastatic colorectal cancer cell lines.

Suwakulsiri W, Rai A, Xu R, Chen M, Greening DW, Simpson RJ.

Biochim Biophys Acta Proteins Proteom. 2019 Dec;1867(12):140171. doi: 10.1016/j.bbapap.2018.11.008. Epub 2018 Nov 29.

PMID:
30502510
28.

B cell homeostasis is maintained during long-duration spaceflight.

Spielmann G, Agha N, Kunz H, Simpson RJ, Crucian B, Mehta S, Laughlin M, Campbell J.

J Appl Physiol (1985). 2019 Feb 1;126(2):469-476. doi: 10.1152/japplphysiol.00789.2018. Epub 2018 Nov 29.

PMID:
30496712
29.

NK cell function is impaired during long-duration spaceflight.

Bigley AB, Agha NH, Baker FL, Spielmann G, Kunz HE, Mylabathula PL, Rooney BV, Laughlin MS, Mehta SK, Pierson DL, Crucian BE, Simpson RJ.

J Appl Physiol (1985). 2019 Apr 1;126(4):842-853. doi: 10.1152/japplphysiol.00761.2018. Epub 2018 Nov 1.

PMID:
30382809
30.

Physical activity and exercise during preoperative pancreatic cancer treatment.

Parker NH, Ngo-Huang A, Lee RE, O'Connor DP, Basen-Engquist KM, Petzel MQB, Wang X, Xiao L, Fogelman DR, Schadler KL, Simpson RJ, Fleming JB, Lee JE, Varadhachary GR, Sahai SK, Katz MHG.

Support Care Cancer. 2019 Jun;27(6):2275-2284. doi: 10.1007/s00520-018-4493-6. Epub 2018 Oct 17.

PMID:
30334105
31.

Baseline Prolonged PR Interval and Outcome of Cardiac Resynchronization Therapy: A Systematic Review and Meta-analysis.

Rattanawong P, Prasitlumkum N, Riangwiwat T, Kanjanahattakij N, Vutthikraivit W, Chongsathidkiet P, Simpson RJ.

Arq Bras Cardiol. 2018 Nov;111(5):710-719. doi: 10.5935/abc.20180198. Epub 2018 Oct 11. English, Portuguese.

32.

Understanding extracellular vesicle diversity - current status.

Greening DW, Simpson RJ.

Expert Rev Proteomics. 2018 Nov;15(11):887-910. doi: 10.1080/14789450.2018.1537788. Epub 2018 Oct 23. Review.

PMID:
30326765
33.

Lipid Profiles in Out-of-Hospital Sudden Unexpected Death.

Hosadurg N, Bogle BM, Joodi G, Sadaf MI, Pursell I, Mendys PM, Mounsey JP, Simpson RJ Jr.

Mayo Clin Proc Innov Qual Outcomes. 2018 Aug 24;2(3):257-266. doi: 10.1016/j.mayocpiqo.2018.06.010. eCollection 2018 Sep.

34.

β2-Adrenergic receptor signaling mediates the preferential mobilization of differentiated subsets of CD8+ T-cells, NK-cells and non-classical monocytes in response to acute exercise in humans.

Graff RM, Kunz HE, Agha NH, Baker FL, Laughlin M, Bigley AB, Markofski MM, LaVoy EC, Katsanis E, Bond RA, Bollard CM, Simpson RJ.

Brain Behav Immun. 2018 Nov;74:143-153. doi: 10.1016/j.bbi.2018.08.017. Epub 2018 Aug 30.

PMID:
30172948
35.

Under-reporting of sudden unexpected death in epilepsy.

Chen S, Joodi G, Devinsky O, Sadaf MI, Pursell IW, Simpson RJ Jr.

Epileptic Disord. 2018 Aug 1;20(4):270-278. doi: 10.1684/epd.2018.0979.

36.

Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions.

Crucian BE, Choukèr A, Simpson RJ, Mehta S, Marshall G, Smith SM, Zwart SR, Heer M, Ponomarev S, Whitmire A, Frippiat JP, Douglas GL, Lorenzi H, Buchheim JI, Makedonas G, Ginsburg GS, Ott CM, Pierson DL, Krieger SS, Baecker N, Sams C.

Front Immunol. 2018 Jun 28;9:1437. doi: 10.3389/fimmu.2018.01437. eCollection 2018. Review.

37.

Calendar time as an instrumental variable in assessing the risk of heart failure with antihyperglycemic drugs.

Gokhale M, Buse JB, DeFilippo Mack C, Jonsson Funk M, Lund J, Simpson RJ, Stürmer T.

Pharmacoepidemiol Drug Saf. 2018 Aug;27(8):857-866. doi: 10.1002/pds.4578. Epub 2018 Jun 26.

PMID:
29943442
38.

Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men.

Ross M, Ingram L, Taylor G, Malone E, Simpson RJ, West D, Florida-James G.

Physiol Rep. 2018 Jun;6(12):e13697. doi: 10.14814/phy2.13697.

39.

A Randomized Controlled Trial of Balloon Dilation as a Treatment for Persistent Eustachian Tube Dysfunction With 1-Year Follow-Up.

Meyer TA, O'Malley EM, Schlosser RJ, Soler ZM, Cai J, Hoy MJ, Slater PW, Cutler JL, Simpson RJ, Clark MJ, Rizk HG, McRackan TR, D'Esposito CF, Nguyen SA.

Otol Neurotol. 2018 Aug;39(7):894-902. doi: 10.1097/MAO.0000000000001853.

40.

Lymphocytes and monocytes egress peripheral blood within minutes after cessation of steady state exercise: A detailed temporal analysis of leukocyte extravasation.

Rooney BV, Bigley AB, LaVoy EC, Laughlin M, Pedlar C, Simpson RJ.

Physiol Behav. 2018 Oct 1;194:260-267. doi: 10.1016/j.physbeh.2018.06.008. Epub 2018 Jun 7.

PMID:
29885920
41.

Approaches to Address Premature Death of Patients When Assessing Patterns of Use of Health Care Services After an Index Event.

Bush M, Simpson RJ Jr, Kucharska-Newton A, Fang G, Stürmer T, Brookhart MA.

Med Care. 2018 Jul;56(7):619-625. doi: 10.1097/MLR.0000000000000923.

42.

Extracellular vesicles in cancer - implications for future improvements in cancer care.

Xu R, Rai A, Chen M, Suwakulsiri W, Greening DW, Simpson RJ.

Nat Rev Clin Oncol. 2018 Oct;15(10):617-638. doi: 10.1038/s41571-018-0036-9. Review.

PMID:
29795272
43.

Cytomegalovirus: an unlikely ally in the fight against blood cancers?

Bigley AB, Baker FL, Simpson RJ.

Clin Exp Immunol. 2018 Sep;193(3):265-274. doi: 10.1111/cei.13152. Review.

44.

A single exercise bout augments adenovirus-specific T-cell mobilization and function.

Kunz HE, Spielmann G, Agha NH, O'Connor DP, Bollard CM, Simpson RJ.

Physiol Behav. 2018 Oct 1;194:56-65. doi: 10.1016/j.physbeh.2018.04.035. Epub 2018 Apr 30.

PMID:
29723594
45.

Modulating the expression of Chtop, a versatile regulator of gene-specific transcription and mRNA export.

Izumikawa K, Ishikawa H, Simpson RJ, Takahashi N.

RNA Biol. 2018;15(7):849-855. doi: 10.1080/15476286.2018.1465795. Epub 2018 May 11. Review.

46.

Classifying medical histories in US Medicare beneficiaries using fixed vs all-available look-back approaches.

Conover MM, Stürmer T, Poole C, Glynn RJ, Simpson RJ Jr, Pate V, Jonsson Funk M.

Pharmacoepidemiol Drug Saf. 2018 Jul;27(7):771-780. doi: 10.1002/pds.4435. Epub 2018 Apr 14.

47.

Medication Use in Women and Men With Sudden Unexpected Death.

Patel S, Conover MM, Joodi G, Chen S, Simpson RJ Jr, Deyo ZM.

Ann Pharmacother. 2018 Sep;52(9):868-875. doi: 10.1177/1060028018771061. Epub 2018 Apr 13.

PMID:
29652176
48.

Ras enhances TGF-β signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1.

Liu S, Iaria J, Simpson RJ, Zhu HJ.

Cell Commun Signal. 2018 Mar 13;16(1):10. doi: 10.1186/s12964-018-0223-4.

49.

Serum Calcium and Risk of Sudden Cardiac Arrest in the General Population.

Husain A, Simpson RJ Jr, Joodi G.

Mayo Clin Proc. 2018 Mar;93(3):392. doi: 10.1016/j.mayocp.2017.12.022. No abstract available.

PMID:
29502569
50.

Exploring links between greenspace and sudden unexpected death: A spatial analysis.

Wu J, Rappazzo KM, Simpson RJ Jr, Joodi G, Pursell IW, Mounsey JP, Cascio WE, Jackson LE.

Environ Int. 2018 Apr;113:114-121. doi: 10.1016/j.envint.2018.01.021. Epub 2018 Feb 6.

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