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Items: 1 to 50 of 138

1.

FDA Approval Summary: Tagraxofusp-erzs For Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm.

Jen EY, Gao X, Li L, Zhuang L, Simpson NE, Aryal B, Wang R, Przepiorka D, Shen YL, Leong R, Liu C, Sheth CM, Bowen S, Goldberg KB, Farrell AT, Blumenthal GM, Pazdur R.

Clin Cancer Res. 2019 Sep 23. pii: clincanres.2329.2019. doi: 10.1158/1078-0432.CCR-19-2329. [Epub ahead of print]

PMID:
31548341
2.

Nonclinical Evaluations of Small-Molecule Oncology Drugs: Integration into Clinical Dose Optimization and Toxicity Management.

Dambach DM, Simpson NE, Jones TW, Brennan RJ, Pazdur R, Palmby TR.

Clin Cancer Res. 2016 Jun 1;22(11):2618-22. doi: 10.1158/1078-0432.CCR-15-2645.

3.

In Situ Transplantation of Alginate Bioencapsulated Adipose Tissues Derived Stem Cells (ADSCs) via Hepatic Injection in a Mouse Model.

Chen MJ, Lu Y, Simpson NE, Beveridge MJ, Elshikha AS, Akbar MA, Tsai HY, Hinske S, Qin J, Grunwitz CR, Chen T, Brantly ML, Song S.

PLoS One. 2015 Sep 15;10(9):e0138184. doi: 10.1371/journal.pone.0138184. eCollection 2015.

4.

Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype.

Simpson NE, Tryndyak VP, Pogribna M, Beland FA, Pogribny IP.

Epigenetics. 2012 Dec 1;7(12):1413-20. doi: 10.4161/epi.22713. Epub 2012 Nov 1.

5.

Cryopreservation effects on intermediary metabolism in a pancreatic substitute: a (13)C nuclear magnetic resonance study.

Ahmad HF, Simpson NE, Lawson AN, Sambanis A.

Tissue Eng Part A. 2012 Nov;18(21-22):2323-31. doi: 10.1089/ten.TEA.2011.0702. Epub 2012 Jul 18.

6.

Glucose oxidation modulates anoikis and tumor metastasis.

Kamarajugadda S, Stemboroski L, Cai Q, Simpson NE, Nayak S, Tan M, Lu J.

Mol Cell Biol. 2012 May;32(10):1893-907. doi: 10.1128/MCB.06248-11. Epub 2012 Mar 19.

7.

An in vitro investigation of metabolically sensitive biomarkers in breast cancer progression.

Simpson NE, Tryndyak VP, Beland FA, Pogribny IP.

Breast Cancer Res Treat. 2012 Jun;133(3):959-68. doi: 10.1007/s10549-011-1871-x. Epub 2011 Nov 20.

PMID:
22101407
8.

Research resource: enhanced genome-wide occupancy of estrogen receptor α by the cochaperone p23 in breast cancer cells.

Simpson NE, Gertz J, Imberg K, Myers RM, Garabedian MJ.

Mol Endocrinol. 2012 Jan;26(1):194-202. doi: 10.1210/me.2011-1068. Epub 2011 Nov 10.

9.

Alterations in histone H4 lysine 20 methylation: implications for cancer detection and prevention.

Koturbash I, Simpson NE, Beland FA, Pogribny IP.

Antioxid Redox Signal. 2012 Jul 15;17(2):365-74. doi: 10.1089/ars.2011.4370. Epub 2011 Dec 14. Review.

PMID:
22035019
10.

In vivo MR studies of glycine and glutathione metabolism in a rat mammary tumor.

Thelwall PE, Simpson NE, Rabbani ZN, Clark MD, Pourdeyhimi R, Macdonald JM, Blackband SJ, Gamcsik MP.

NMR Biomed. 2012 Feb;25(2):271-8. doi: 10.1002/nbm.1745. Epub 2011 Jul 12.

11.

Non-invasive monitoring of L-2-oxothiazolidine-4-carboxylate metabolism in the rat brain by in vivo 13C magnetic resonance spectroscopy.

Gamcsik MP, Clark MD, Ludeman SM, Springer JB, D'Alessandro MA, Simpson NE, Pourdeyhimi R, Johnson CB, Teeter SD, Blackband SJ, Thelwall PE.

Neurochem Res. 2011 Mar;36(3):443-51. doi: 10.1007/s11064-010-0362-5. Epub 2010 Dec 15.

12.

High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance.

Simpson NE, Lambert WM, Watkins R, Giashuddin S, Huang SJ, Oxelmark E, Arju R, Hochman T, Goldberg JD, Schneider RJ, Reiz LF, Soares FA, Logan SK, Garabedian MJ.

Cancer Res. 2010 Nov 1;70(21):8446-56. doi: 10.1158/0008-5472.CAN-10-1590. Epub 2010 Sep 16.

13.

Limited beneficial effects of perfluorocarbon emulsions on encapsulated cells in culture: experimental and modeling studies.

Goh F, Gross JD, Simpson NE, Sambanis A.

J Biotechnol. 2010 Oct 15;150(2):232-9. doi: 10.1016/j.jbiotec.2010.08.013. Epub 2010 Sep 8.

14.

Development of an inductively coupled MR coil system for imaging and spectroscopic analysis of an implantable bioartificial construct at 11.1 T.

Volland NA, Mareci TH, Constantinidis I, Simpson NE.

Magn Reson Med. 2010 Apr;63(4):998-1006. doi: 10.1002/mrm.22268.

15.

Use of magnetic nanoparticles to monitor alginate-encapsulated betaTC-tet cells.

Constantinidis I, Grant SC, Simpson NE, Oca-Cossio JA, Sweeney CA, Mao H, Blackband SJ, Sambanis A.

Magn Reson Med. 2009 Feb;61(2):282-90. doi: 10.1002/mrm.21833.

16.

Novel synthesis of cerium oxide nanoparticles for free radical scavenging.

Tsai YY, Oca-Cossio J, Agering K, Simpson NE, Atkinson MA, Wasserfall CH, Constantinidis I, Sigmund W.

Nanomedicine (Lond). 2007 Jun;2(3):325-32.

PMID:
17716177
17.

13C NMR isotopomeric analysis and its application in the study of endocrine cell metabolism and function.

Simpson NE, Constantinidis I.

Acta Biomed. 2007;78 Suppl 1:99-112.

PMID:
17465328
18.

Non-invasive evaluation of alginate/poly-l-lysine/alginate microcapsules by magnetic resonance microscopy.

Constantinidis I, Grant SC, Celper S, Gauffin-Holmberg I, Agering K, Oca-Cossio JA, Bui JD, Flint J, Hamaty C, Simpson NE, Blackband SJ.

Biomaterials. 2007 May;28(15):2438-45. Epub 2007 Jan 8.

19.

Non-invasive monitoring of tissue-engineered pancreatic constructs by NMR techniques.

Constantinidis I, Simpson NE, Grant SC, Blackband SJ, Long RC Jr, Sambanis A.

Adv Exp Med Biol. 2006;585:261-76. No abstract available.

PMID:
17120790
20.

Magnetic resonance spectroscopic investigation of mitochondrial fuel metabolism and energetics in cultured human fibroblasts: effects of pyruvate dehydrogenase complex deficiency and dichloroacetate.

Simpson NE, Han Z, Berendzen KM, Sweeney CA, Oca-Cossio JA, Constantinidis I, Stacpoole PW.

Mol Genet Metab. 2006 Sep-Oct;89(1-2):97-105. Epub 2006 Jun 12.

PMID:
16765624
21.

Insights into the role of anaplerosis in insulin secretion: A 13C NMR study.

Simpson NE, Khokhlova N, Oca-Cossio JA, Constantinidis I.

Diabetologia. 2006 Jun;49(6):1338-48. Epub 2006 Mar 31.

PMID:
16575559
22.

Serum IGF-1 in treated acromegaly - how normal is "normal"?

Lansang C, Chitaia N, Simpson NE, Kennedy L.

Pituitary. 2005;8(2):135-8.

PMID:
16379035
23.

Biochemical consequences of alginate encapsulation: a NMR study of insulin-secreting cells.

Simpson NE, Grant SC, Gustavsson L, Peltonen VM, Blackband SJ, Constantinidis I.

Biomaterials. 2006 Apr;27(12):2577-86. Epub 2005 Dec 20.

PMID:
16364429
24.

Noninvasive in vivo detection of glutathione metabolism in tumors.

Thelwall PE, Yemin AY, Gillian TL, Simpson NE, Kasibhatla MS, Rabbani ZN, Macdonald JM, Blackband SJ, Gamcsik MP.

Cancer Res. 2005 Nov 15;65(22):10149-53.

25.

Effects of alginate encapsulation on mitochondrial activity.

Oca-Cossio J, Simpson NE, Han Z, Stacpoole PW, Constantinidis I.

J Mater Sci Mater Med. 2005 Jun;16(6):521-4.

PMID:
15928867
26.

Alginate assessment by NMR microscopy.

Grant SC, Celper S, Gauffin-Holmberg I, Simpson NE, Blackband SJ, Constantinidis I.

J Mater Sci Mater Med. 2005 Jun;16(6):511-4.

PMID:
15928865
27.

Effects of growth regulation on conditionally-transformed alginate-entrapped insulin secreting cell lines in vitro.

Simpson NE, Khokhlova N, Oca-Cossio JA, McFarlane SS, Simpson CP, Constantinidis I.

Biomaterials. 2005 Aug;26(22):4633-41. Epub 2005 Jan 13.

PMID:
15722133
28.

Magnetically labeled insulin-secreting cells.

Oca-Cossio J, Mao H, Khokhlova N, Kennedy CM, Kennedy JW, Stabler CL, Hao E, Sambanis A, Simpson NE, Constantinidis I.

Biochem Biophys Res Commun. 2004 Jun 25;319(2):569-75.

PMID:
15178444
29.

The role of the CaCl2-guluronic acid interaction on alginate encapsulated betaTC3 cells.

Simpson NE, Stabler CL, Simpson CP, Sambanis A, Constantinidis I.

Biomaterials. 2004 Jun;25(13):2603-10.

PMID:
14751746
30.

NMR properties of alginate microbeads.

Simpson NE, Grant SC, Blackband SJ, Constantinidis I.

Biomaterials. 2003 Dec;24(27):4941-8.

PMID:
14559007
31.

Synthesis and evaluation of 2-amino-4-[(18)F]fluoro-2-methylbutanoic acid (FAMB): relationship of amino acid transport to tumor imaging properties of branched fluorinated amino acids.

McConathy J, Martarello L, Malveaux EJ, Camp VM, Simpson NE, Simpson CP, Bowers GD, Zhang Z, Olson JJ, Goodman MM.

Nucl Med Biol. 2003 Jul;30(5):477-90.

PMID:
12831985
32.

Synthesis of syn- and anti-1-amino-3-[18F]fluoromethyl-cyclobutane-1-carboxylic acid (FMACBC), potential PET ligands for tumor detection.

Martarello L, McConathy J, Camp VM, Malveaux EJ, Simpson NE, Simpson CP, Olson JJ, Bowers GD, Goodman MM.

J Med Chem. 2002 May 23;45(11):2250-9.

PMID:
12014963
33.

Radiolabeled amino acids for tumor imaging with PET: radiosynthesis and biological evaluation of 2-amino-3-[18F]fluoro-2-methylpropanoic acid and 3-[18F]fluoro-2-methyl-2-(methylamino)propanoic acid.

McConathy J, Martarello L, Malveaux EJ, Camp VM, Simpson NE, Simpson CP, Bowers GD, Olson JJ, Goodman MM.

J Med Chem. 2002 May 23;45(11):2240-9.

PMID:
12014962
34.

Effects of pH on murine insulinoma betaTC3 cells.

Simpson NE, Bennett LK, Papas KK, Sambanis A, Constantinidis I.

Biochem Biophys Res Commun. 2000 Jul 14;273(3):937-41.

PMID:
10891351
35.
36.
37.

Identification and characterization of a gene at D10S94 in the MEN2A region.

McDonald H, Smailus D, Jenkins H, Adams K, Simpson NE, Goodfellow PJ.

Genomics. 1992 Jun;13(2):344-8.

PMID:
1351868
38.

Measurement of relative regional tumor blood flow in mice by deuterium NMR imaging.

Evelhoch JL, McDouall JB, Mattiello J, Simpson NE.

Magn Reson Med. 1992 Mar;24(1):42-52.

PMID:
1532621
39.

A preliminary analysis of consortium data for markers tightly linked to multiple endocrine neoplasia type 2A.

Lichter JB, Hackleman SM, Ponder BA, Easton D, Narod SA, Lenoir GM, Gagel RF, Simpson NE, Gardner E, Goodfellow PJ, et al.

Henry Ford Hosp Med J. 1992;40(3-4):205-9.

PMID:
1362406
40.

A physical map of human chromosome 10 and a comparison with an existing genetic map.

Carson NL, Simpson NE.

Genomics. 1991 Oct;11(2):379-88.

PMID:
1769653
41.

Linkage exclusion between the autosomal dominant polycystic kidney disease locus and chromosome 16 markers in a new family.

Brissenden JE, Roscoe JM, Simpson NE, Silverman M.

J Am Soc Nephrol. 1991 Oct;2(4):913-9.

42.

Size dependence of regional blood flow in murine tumours using deuterium magnetic resonance imaging.

Larcombe-McDouall JB, Mattiello J, McCoy CL, Simpson NE, Seyedsadr M, Evelhoch JL.

Int J Radiat Biol. 1991 Jul-Aug;60(1-2):109-13. No abstract available.

PMID:
1677956
43.

A PvuII RFLP detected by pOB231 at CDC2 on human chromosome 10.

Carson NL, Myers S, Simpson NE.

Nucleic Acids Res. 1991 Jan 11;19(1):196. No abstract available.

44.

A new DNA marker (D10S94) very tightly linked to the multiple endocrine neoplasia type 2A (MEN2A) locus.

Goodfellow PJ, Myers S, Anderson LL, Brooks-Wilson AR, Simpson NE.

Am J Hum Genet. 1990 Dec;47(6):952-6.

45.
46.

A refined linkage map for DNA markers around the pericentromeric region of chromosome 10.

Wu JS, Myers S, Carson N, Kidd JR, Anderson L, Castiglione CM, Hoyle LS, Lichter JB, Sukhatme VP, Simpson NE, et al.

Genomics. 1990 Nov;8(3):461-8.

PMID:
1981049
47.

Three polymorphisms at the D10S85 locus.

Goodfellow PJ, Brooks-Wilson AR, Smailus D, Myers S, Anderson L, Simpson NE.

Nucleic Acids Res. 1990 Aug 25;18(16):4960. No abstract available.

48.

Two polymorphisms at the D10S94 locus.

Brooks-Wilson AR, Smailus D, Myers S, Anderson L, Simpson NE, Goodfellow PJ.

Nucleic Acids Res. 1990 Aug 25;18(16):4959. No abstract available.

49.

Two HinfI RFLPs detected by p alpha 10RP8 at D10Z1.

Carson NL, Simpson NE.

Nucleic Acids Res. 1990 Apr 11;18(7):1932. No abstract available.

50.

Search for the gene for multiple endocrine neoplasia type 2A.

Kidd KK, Simpson NE.

Recent Prog Horm Res. 1990;46:305-41; discussion 341-3. Review. No abstract available.

PMID:
2281187

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