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Modification of the Mammalian Endomembrane System in Healthy and Diseased Cells.

Simpson JC.

Int J Mol Sci. 2020 Mar 20;21(6). pii: E2133. doi: 10.3390/ijms21062133.


Histological characterization of interneurons in Alzheimer's disease reveals a loss of somatostatin interneurons in the temporal cortex.

Waller R, Mandeya M, Viney E, Simpson JE, Wharton SB.

Neuropathology. 2020 Mar 30. doi: 10.1111/neup.12649. [Epub ahead of print]


Video-interpreting for cognitive assessments: An intervention study and micro-costing analysis.

Hwang K, De Silva A, Simpson JA, LoGiudice D, Engel L, Gilbert AS, Croy S, Haralambous B.

J Telemed Telecare. 2020 Mar 30:1357633X20914445. doi: 10.1177/1357633X20914445. [Epub ahead of print] No abstract available.


A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor.

Maher TM, Simpson JK, Porter JC, Wilson FJ, Chan R, Eames R, Cui Y, Siederer S, Parry S, Kenny J, Slack RJ, Sahota J, Paul L, Saunders P, Molyneaux PL, Lukey PT, Rizzo G, Searle GE, Marshall RP, Saleem A, Kang'ombe AR, Fairman D, Fahy WA, Vahdati-Bolouri M.

Respir Res. 2020 Mar 26;21(1):75. doi: 10.1186/s12931-020-01339-7.


Hemodynamic assessment of diastolic function for experimental models.

Ogilvie LM, Edgett BA, Huber JS, Platt MJ, Eberl HJ, Lutchmedial S, Brunt KR, Simpson JA.

Am J Physiol Heart Circ Physiol. 2020 Mar 27. doi: 10.1152/ajpheart.00705.2019. [Epub ahead of print]


Procedural, pregnancy, and short-term outcomes after fetal aortic valvuloplasty.

Patel ND, Nageotte S, Ing FF, Armstrong AK, Chmait R, Detterich JA, Galindo A, Gardiner H, Grinenco S, Herberg U, Jaeggi E, Morris SA, Oepkes D, Simpson JM, Moon-Grady A, Pruetz JD.

Catheter Cardiovasc Interv. 2020 Mar 26. doi: 10.1002/ccd.28846. [Epub ahead of print]


Improving pelvic floor health: advice for nurses and their patients.

Simpson J.

Br J Nurs. 2020 Mar 26;29(6):346-348. doi: 10.12968/bjon.2020.29.6.346.


Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes.

Morris S, Geoghegan ND, Sadler JBA, Koester AM, Black HL, Laub M, Miller L, Heffernan L, Simpson JC, Mastick CC, Cooper J, Gadegaard N, Bryant NJ, Gould GW.

PeerJ. 2020 Mar 5;8:e8751. doi: 10.7717/peerj.8751. eCollection 2020.


Explaining the link between adiposity and colorectal cancer risk in men and postmenopausal women in the UK Biobank: a sequential causal mediation analysis.

Dashti SG, Viallon V, Simpson JA, Karahalios A, Moreno-Betancur M, English DR, Gunter MJ, Murphy N.

Int J Cancer. 2020 Mar 17. doi: 10.1002/ijc.32980. [Epub ahead of print]


Dilatation of the Aorta in Bicuspid Aortic Valve Disease.

Simpson JM, Pushparajah K.

Circ Cardiovasc Imaging. 2020 Mar;13(3):e010448. doi: 10.1161/CIRCIMAGING.120.010448. Epub 2020 Mar 17. No abstract available.


Implications of Analysis Unit on Epidemiology of Multimodal Imaging-Defined Reticular Pseudodrusen: When 2 Eyes Are Better Than 1.

McGuinness MB, Guymer RH, Simpson JA.

JAMA Ophthalmol. 2020 Mar 12. doi: 10.1001/jamaophthalmol.2020.0262. [Epub ahead of print] No abstract available.


Spatial Comparisons of Mechanosensory Information Govern the Grooming Sequence in Drosophila.

Zhang N, Guo L, Simpson JH.

Curr Biol. 2020 Mar 23;30(6):988-1001.e4. doi: 10.1016/j.cub.2020.01.045. Epub 2020 Mar 5.


SCLpred-EMS: subcellular localization prediction of endomembrane system and secretory pathway proteins by Deep N-to-1 Convolutional Neural Networks.

Kaleel M, Zheng Y, Chen J, Feng X, Simpson JC, Pollastri G, Mooney C.

Bioinformatics. 2020 Mar 6. pii: btaa156. doi: 10.1093/bioinformatics/btaa156. [Epub ahead of print]


What does the increasing prevalence of obesity mean for the management of asthma and airways disease?

Simpson JL, Scott HA.

J Bras Pneumol. 2020 Mar 2;46(1):e20200048. doi: 10.1590/1806-3713/e20200048. English, Portuguese. No abstract available.


Life stress and cortisol reactivity: An exploratory analysis of the effects of stress exposure across life on HPA-axis functioning.

Young ES, Doom JR, Farrell AK, Carlson EA, Englund MM, Miller GE, Gunnar MR, Roisman GI, Simpson JA.

Dev Psychopathol. 2020 Mar 3:1-12. doi: 10.1017/S0954579419001779. [Epub ahead of print]


A potpourri of biostatistical research: Special Issue for ISCB ASC 2018.

Carlin J, Kasza J, Moreno-Betancur M, Simpson J, Bartlett J, Metcalfe C, Lee K.

Biom J. 2020 Mar;62(2):267-269. doi: 10.1002/bimj.202000030. No abstract available.


Isospin Properties of Nuclear Pair Correlations from the Level Structure of the Self-Conjugate Nucleus ^{88}Ru.

Cederwall B, Liu X, Aktas Ö, Ertoprak A, Zhang W, Qi C, Clément E, de France G, Ralet D, Gadea A, Goasduff A, Jaworski G, Kuti I, Nyakó BM, Nyberg J, Palacz M, Wadsworth R, Valiente-Dobón JJ, Al-Azri H, Ataç Nyberg A, Bäck T, de Angelis G, Doncel M, Dudouet J, Gottardo A, Jurado M, Ljungvall J, Mengoni D, Napoli DR, Petrache CM, Sohler D, Timár J, Barrientos D, Bednarczyk P, Benzoni G, Birkenbach B, Boston AJ, Boston HC, Burrows I, Charles L, Ciemala M, Crespi FCL, Cullen DM, Désesquelles P, Domingo-Pardo C, Eberth J, Erduran N, Ertürk S, González V, Goupil J, Hess H, Huyuk T, Jungclaus A, Korten W, Lemasson A, Leoni S, Maj A, Menegazzo R, Million B, Perez-Vidal RM, Podolyak Z, Pullia A, Recchia F, Reiter P, Saillant F, Salsac MD, Sanchis E, Simpson J, Stezowski O, Theisen C, Zielińska M.

Phys Rev Lett. 2020 Feb 14;124(6):062501. doi: 10.1103/PhysRevLett.124.062501.


RSV Infection Promotes Necroptosis and HMGB1 Release by Airway Epithelial Cells.

Simpson J, Loh Z, Ullah MA, Lynch JP, Werder RB, Collinson N, Zhang V, Dondelinger Y, Bertrand MJM, Everard ML, Blyth CC, Hartel G, Van Oosterhout AJ, Gough PJ, Bertin J, Upham JW, Spann KM, Phipps S.

Am J Respir Crit Care Med. 2020 Feb 27. doi: 10.1164/rccm.201906-1149OC. [Epub ahead of print]


Correction to: A comparison of methods to estimate the survivor average causal effect in the presence of missing data: a simulation study.

McGuinness MB, Kasza J, Karahalios A, Guymer RH, Finger RP, Simpson JA.

BMC Med Res Methodol. 2020 Feb 27;20(1):40. doi: 10.1186/s12874-020-00935-x.


Relationship between early follow-up and readmission within 30 and 90 days after ischemic stroke.

Leppert MH, Sillau S, Lindrooth RC, Poisson SN, Campbell JD, Simpson JR.

Neurology. 2020 Mar 24;94(12):e1249-e1258. doi: 10.1212/WNL.0000000000009135. Epub 2020 Feb 20.


The risk of morbidity and mortality following recurrent malaria in Papua, Indonesia: a retrospective cohort study.

Dini S, Douglas NM, Poespoprodjo JR, Kenangalem E, Sugiarto P, Plumb ID, Price RN, Simpson JA.

BMC Med. 2020 Feb 20;18(1):28. doi: 10.1186/s12916-020-1497-0.


Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells.

De Santi C, Fernández Fernández E, Gaul R, Vencken S, Glasgow A, Oglesby IK, Hurley K, Hawkins F, Mitash N, Mu F, Raoof R, Henshall DC, Cutrona MB, Simpson JC, Harvey BJ, Linnane B, McNally P, Cryan SA, MacLoughlin R, Swiatecka-Urban A, Greene CM.

Mol Ther. 2020 Feb 6. pii: S1525-0016(20)30087-3. doi: 10.1016/j.ymthe.2020.02.001. [Epub ahead of print]


The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy.

Owasil R, O'Neill R, Keable A, Nimmo J, MacGregor Sharp M, Kelly L, Saito S, Simpson JE, Weller RO, Smith C, Attems J, Wharton SB, Yuen HM, Carare RO.

Int J Mol Sci. 2020 Feb 12;21(4). pii: E1225. doi: 10.3390/ijms21041225.


Virtual linear measurement system for accurate quantification of medical images.

Wheeler G, Deng S, Pushparajah K, Schnabel JA, Simpson JM, Gomez A.

Healthc Technol Lett. 2019 Dec 2;6(6):220-225. doi: 10.1049/htl.2019.0074. eCollection 2019 Dec.


Early Postnatal Echocardiography in Neonates with a Prenatal Suspicion of Coarctation of the Aorta.

Vigneswaran TV, Bellsham-Revell HR, Chubb H, Simpson JM.

Pediatr Cardiol. 2020 Feb 7. doi: 10.1007/s00246-020-02310-5. [Epub ahead of print]


3D/4D spatiotemporal image correlation (STIC) fetal echocardiography provides incremental benefit in predicting the postnatal surgical approach in double outlet right ventricle.

Karmegaraj B, Kumar S, Srimurugan B, Sudhakar A, Simpson JM, Vaidyanathan B.

Ultrasound Obstet Gynecol. 2020 Feb 5. doi: 10.1002/uog.21988. [Epub ahead of print]


Metformin use in obese mothers is associated with improved cardiovascular profile in the offspring.

Panagiotopoulou O, Syngelaki A, Georgiopoulos G, Simpson J, Akolekar R, Shehata H, Nicolaides K, Charakida M.

Am J Obstet Gynecol. 2020 Feb 1. pii: S0002-9378(20)30109-5. doi: 10.1016/j.ajog.2020.01.054. [Epub ahead of print]


Self-disgust mediates the relationship between childhood adversities and psychosis.

Simpson J, Helliwell B, Varese F, Powell P.

Br J Clin Psychol. 2020 Feb 3. doi: 10.1111/bjc.12245. [Epub ahead of print]


Three-dimensional water mapping of succulent Agave victoriae-reginae leaves by terahertz imaging.

Singh AK, Pérez-López AV, Simpson J, Castro-Camus E.

Sci Rep. 2020 Jan 29;10(1):1404. doi: 10.1038/s41598-020-58277-z.


Prognostic Models Derived in PARADIGM-HF and Validated in ATMOSPHERE and the Swedish Heart Failure Registry to Predict Mortality and Morbidity in Chronic Heart Failure.

Simpson J, Jhund PS, Lund LH, Padmanabhan S, Claggett BL, Shen L, Petrie MC, Abraham WT, Desai AS, Dickstein K, Køber L, Packer M, Rouleau JL, Mueller-Velten G, Solomon SD, Swedberg K, Zile MR, McMurray JJV.

JAMA Cardiol. 2020 Jan 29. doi: 10.1001/jamacardio.2019.5850. [Epub ahead of print] Erratum in: JAMA Cardiol. 2020 Mar 11;:.


An objective methodology capturing online commodity marketing and other harms.

Vaipuna T, Allison L, Bhasin A, Choi K, Chu A, Grice K, Hay A, Huang S, Jarvis EM, Laing B, Lewis A, Moriarty RH, Obafemi T, Rajendra P, Simpson J, Tay A, Yang A, Smith M, Gage R, Chambers T, Lyons A, Ormandy J, Signal L.

Health Promot Int. 2020 Jan 27. pii: daz131. doi: 10.1093/heapro/daz131. [Epub ahead of print]


The invisible burden of malaria-attributable stillbirths.

Fowkes FJI, Davidson E, Moore KA, McGready R, Simpson JA.

Lancet. 2020 Jan 25;395(10220):268. doi: 10.1016/S0140-6736(19)33011-9. No abstract available.


Early Age at Natural Menopause Is Related to Lower Post-Bronchodilator Lung Function. A Longitudinal Population-based Study.

Campbell B, Bui DS, Simpson JA, Lodge CJ, Lowe AJ, Bowatte G, Leynaert B, Real FG, Thomas PS, Giles GG, Johns DP, Garcia-Aymerich J, Hopper JL, Jarvis D, Abramson MJ, Walters EH, Perret JL, Dharmage SC.

Ann Am Thorac Soc. 2020 Apr;17(4):429-437. doi: 10.1513/AnnalsATS.201902-180OC.


Integrating intrapersonal and interpersonal processes: a key step in advancing the science of behavior change.

Rothman AJ, Simpson JA, Huelsnitz CO, Jones RE, Scholz U.

Health Psychol Rev. 2020 Mar;14(1):182-187. doi: 10.1080/17437199.2020.1719183. No abstract available.


Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks.

Zhu H, Uusküla-Reimand L, Isaev K, Wadi L, Alizada A, Shuai S, Huang V, Aduluso-Nwaobasi D, Paczkowska M, Abd-Rabbo D, Ocsenas O, Liang M, Thompson JD, Li Y, Ruan L, Krassowski M, Dzneladze I, Simpson JT, Lupien M, Stein LD, Boutros PC, Wilson MD, Reimand J.

Mol Cell. 2020 Mar 19;77(6):1307-1321.e10. doi: 10.1016/j.molcel.2019.12.027. Epub 2020 Jan 17.


Effect of probiotics on multi-resistant organism colonisation in persons with spinal cord injury: secondary outcome of ProSCIUTTU, a randomised placebo-controlled trial.

Toh SL, Lee BB, Simpson JM, Rice SA, Kotsiou G, Marial O, Ryan S.

Spinal Cord. 2020 Jan 17. doi: 10.1038/s41393-020-0420-z. [Epub ahead of print]


NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain.

Fadul MM, Garwood CJ, Waller R, Garrett N, Heath PR, Matthews FE, Brayne C, Wharton SB, Simpson JE.

Int J Mol Sci. 2020 Jan 4;21(1). pii: E340. doi: 10.3390/ijms21010340.


Pregnancy-specific malarial immunity and risk of malaria in pregnancy and adverse birth outcomes: a systematic review.

Cutts JC, Agius PA, Zaw Lin, Powell R, Moore K, Draper B, Simpson JA, Fowkes FJI.

BMC Med. 2020 Jan 16;18(1):14. doi: 10.1186/s12916-019-1467-6.


Multiple imputation methods for handling incomplete longitudinal and clustered data where the target analysis is a linear mixed effects model.

Huque MH, Moreno-Betancur M, Quartagno M, Simpson JA, Carlin JB, Lee KJ.

Biom J. 2020 Mar;62(2):444-466. doi: 10.1002/bimj.201900051. Epub 2020 Jan 9.


A community effort to create standards for evaluating tumor subclonal reconstruction.

Salcedo A, Tarabichi M, Espiritu SMG, Deshwar AG, David M, Wilson NM, Dentro S, Wintersinger JA, Liu LY, Ko M, Sivanandan S, Zhang H, Zhu K, Ou Yang TH, Chilton JM, Buchanan A, Lalansingh CM, P'ng C, Anghel CV, Umar I, Lo B, Zou W; DREAM SMC-Het Participants, Simpson JT, Stuart JM, Anastassiou D, Guan Y, Ewing AD, Ellrott K, Wedge DC, Morris Q, Van Loo P, Boutros PC.

Nat Biotechnol. 2020 Jan;38(1):97-107. doi: 10.1038/s41587-019-0364-z. Epub 2020 Jan 9.


Infants' attachment insecurity predicts attachment-relevant emotion regulation strategies in adulthood.

Girme YU, Jones RE, Fleck C, Simpson JA, Overall NC.

Emotion. 2020 Jan 9. doi: 10.1037/emo0000721. [Epub ahead of print]


Echocardiographic examination of mitral valve abnormalities in the paediatric population: current practices.

Cantinotti M, Giordano R, Koestenberger M, Voges I, Santoro G, Franchi E, Assanta N, Valverde I, Simpson J, Kutty S.

Cardiol Young. 2020 Jan;30(1):1-11. doi: 10.1017/S1047951119003196. Epub 2020 Jan 8.


Phase I Study of Yttrium-90 Radiolabeled M5A Anti-Carcinoembryonic Antigen Humanized Antibody in Patients with Advanced Carcinoembryonic Antigen Producing Malignancies.

Akhavan D, Yazaki P, Yamauchi D, Simpson J, Frankel PH, Bading J, Colcher D, Poku K, Chen YJ, Lim D, Cristea M, Wu A, Shively J, Wong JYC.

Cancer Biother Radiopharm. 2020 Feb;35(1):10-15. doi: 10.1089/cbr.2019.2992. Epub 2020 Jan 7.


Intraoperative End-Tidal CO₂ as a Predictor of Mortality in Trauma Patients Receiving Massive Transfusion Protocol.

Demaree C, Simpson JT, Smith A, Guidry C, McGrew P, Schroll R, McGinness C, Tatum D, Duchesne J.

Am Surg. 2019 Dec 1;85(12):e617-e619. No abstract available.


Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma.

Sánchez-Ovando S, Baines KJ, Barker D, Wark PA, Simpson JL.

Immun Inflamm Dis. 2020 Mar;8(1):40-49. doi: 10.1002/iid3.282. Epub 2020 Jan 5.


Coparenting and Relationship Satisfaction in Mothers: The Moderating Role of Sociosexuality.

Lamela D, Figueiredo B, Jongenelen I, Morais A, Simpson JA.

Arch Sex Behav. 2020 Apr;49(3):861-870. doi: 10.1007/s10508-019-01548-2. Epub 2020 Jan 2.


Lower Limb Joint Kinetics During a Side-Cutting Task in Participants With or Without Chronic Ankle Instability.

Simpson JD, Stewart EM, Turner AJ, Macias DM, Chander H, Knight AC.

J Athl Train. 2020 Feb;55(2):169-175. doi: 10.4085/1062-6050-334-18. Epub 2020 Jan 2.


Efficacy of azithromycin in severe asthma from the AMAZES randomised trial.

Gibson PG, Yang IA, Upham JW, Reynolds PN, Hodge S, James AL, Jenkins C, Peters MJ, Marks GB, Baraket M, Powell H, Simpson JL.

ERJ Open Res. 2019 Dec 23;5(4). pii: 00056-2019. doi: 10.1183/23120541.00056-2019. eCollection 2019 Oct.


Sustained adherence to a Mediterranean diet and physical activity on all-cause mortality in the Melbourne Collaborative Cohort Study: application of the g-formula.

Williamson EJ, Polak J, Simpson JA, Giles GG, English DR, Hodge A, Gurrin L, Forbes AB.

BMC Public Health. 2019 Dec 26;19(1):1733. doi: 10.1186/s12889-019-7919-2.


Early clinical outcomes of a rapid colorectal cancer diagnosis pathway using faecal immunochemical testing in Nottingham.

Chapman C, Thomas C, Morling J, Tangri A, Oliver S, Simpson JA, Humes DJ, Banerjea A.

Colorectal Dis. 2019 Dec 26. doi: 10.1111/codi.14944. [Epub ahead of print]


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