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Clinically Meaningful Responses to Dupilumab in Adolescents with Uncontrolled Moderate-to-Severe Atopic Dermatitis: Post-hoc Analyses from a Randomized Clinical Trial.

Paller AS, Bansal A, Simpson EL, Boguniewicz M, Blauvelt A, Siegfried EC, Guttman-Yassky E, Hultsch T, Chen Z, Mina-Osorio P, Lu Y, Rossi AB, He X, Kamal M, Graham NMH, Pirozzi G, Ruddy M, Eckert L, Gadkari A.

Am J Clin Dermatol. 2019 Dec 10. doi: 10.1007/s40257-019-00478-y. [Epub ahead of print]


Quality of Life and Disease Impact of Atopic Dermatitis and Psoriasis on Children and Their Families.

Na CH, Chung J, Simpson EL.

Children (Basel). 2019 Dec 2;6(12). pii: E133. doi: 10.3390/children6120133. Review.


Health cognitions mediate physical (in)activity and walking in midlife women.

Walsh A, Simpson EEA.

Maturitas. 2020 Jan;131:14-20. doi: 10.1016/j.maturitas.2019.10.005. Epub 2019 Oct 16.


Evaluating patient-perceived control of atopic dermatitis: design, validation, and scoring of the Atopic Dermatitis Control Tool (ADCT).

Pariser DM, Simpson EL, Gadkari A, Bieber T, Margolis DJ, Brown M, Nelson L, Mahajan P, Reaney M, Guillemin I, Mallya UG, Eckert L.

Curr Med Res Opin. 2019 Nov 28:1. doi: 10.1080/03007995.2019.1699516. [Epub ahead of print]


A survey in uncharted territory: A collaborative study to explore the approach to atopic dermatitis patient management in allopathy and naturopathy.

Dhossche J, Corn J, Simpson EL, Funk T.

Pediatr Dermatol. 2019 Nov 19. doi: 10.1111/pde.14036. [Epub ahead of print]


Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis: A Phase 3 Randomized Clinical Trial.

Simpson EL, Paller AS, Siegfried EC, Boguniewicz M, Sher L, Gooderham MJ, Beck LA, Guttman-Yassky E, Pariser D, Blauvelt A, Weisman J, Lockshin B, Hultsch T, Zhang Q, Kamal MA, Davis JD, Akinlade B, Staudinger H, Hamilton JD, Graham NMH, Pirozzi G, Gadkari A, Eckert L, Stahl N, Yancopoulos GD, Ruddy M, Bansal A.

JAMA Dermatol. 2019 Nov 6. doi: 10.1001/jamadermatol.2019.3336. [Epub ahead of print]


Validation of the Atopic Dermatitis Control Tool (ADCT©) using a longitudinal survey of biologic-treated patients with atopic dermatitis.

Simpson E, Eckert L, Gadkari A, Mallya UG, Yang M, Nelson L, Brown M, Reaney M, Mahajan P, Guillemin I, Boguniewicz M, Pariser D.

BMC Dermatol. 2019 Nov 6;19(1):15. doi: 10.1186/s12895-019-0095-3.


Reporting of Patient Global Assessments in Atopic Dermatitis Randomized Controlled Trials.

Grinich EE, Pawlitschek T, Simpson EL.

Dermatitis. 2019 Oct 28. doi: 10.1097/DER.0000000000000534. [Epub ahead of print] No abstract available.


Responder Threshold for Patient-Oriented Eczema Measure (POEM) and Children's Dermatology Life Quality Index (CDLQI) in Adolescents with Atopic Dermatitis.

Simpson EL, de Bruin-Weller M, Eckert L, Whalley D, Guillemin I, Reaney M, Chen Z, Nelson L, Qin S, Bansal A, Gadkari A.

Dermatol Ther (Heidelb). 2019 Dec;9(4):799-805. doi: 10.1007/s13555-019-00333-2. Epub 2019 Oct 22.


Clinical effectiveness of denosumab, raloxifene, romosozumab, and teriparatide for the prevention of osteoporotic fragility fractures: A systematic review and network meta-analysis.

Simpson EL, Martyn-St James M, Hamilton J, Wong R, Gittoes N, Selby P, Davis S.

Bone. 2020 Jan;130:115081. doi: 10.1016/j.bone.2019.115081. Epub 2019 Oct 15.


Selection design phase II trial of high dosages of tamoxifen and creatine in amyotrophic lateral sclerosis.

Babu S, Macklin EA, Jackson KE, Simpson E, Mahoney K, Yu H, Walker J, Simmons Z, David WS, Barkhaus PE, Simionescu L, Dimachkie MM, Pestronk A, Salameh JS, Weiss MD, Brooks BR, Schoenfeld D, Shefner J, Aggarwal S, Cudkowicz ME, Atassi N.

Amyotroph Lateral Scler Frontotemporal Degener. 2019 Oct 14:1-9. doi: 10.1080/21678421.2019.1672750. [Epub ahead of print]


The Patient-reported Disease Burden in Adults with Atopic Dermatitis: A Cross-sectional Study in Europe and Canada.

de Bruin-Weller M, Gadkari A, Auziere S, Simpson EL, Puig L, Barbarot S, Girolomoni G, Papp K, Pink AE, Saba G, Werfel T, Eckert L.

J Eur Acad Dermatol Venereol. 2019 Oct 6. doi: 10.1111/jdv.16003. [Epub ahead of print]


Implementation of the Neonatal Sepsis Calculator in Early-Onset Sepsis and Maternal Chorioamnionitis.

Akangire G, Simpson E, Weiner J, Noel-MacDonnell J, Petrikin J, Sheehan M.

Adv Neonatal Care. 2019 Sep 27. doi: 10.1097/ANC.0000000000000668. [Epub ahead of print]


The impact of reduced red and processed meat consumption on cardiovascular risk factors; an intervention trial in healthy volunteers.

Simpson EJ, Clark M, Razak AA, Salter A.

Food Funct. 2019 Oct 16;10(10):6690-6698. doi: 10.1039/c9fo00758j.


Comprehensive Cis-Regulation Analysis of Genetic Variants in Human Lymphoblastoid Cell Lines.

Wang Y, He B, Zhao Y, Reiter JL, Chen SX, Simpson E, Feng W, Liu Y.

Front Genet. 2019 Sep 10;10:806. doi: 10.3389/fgene.2019.00806. eCollection 2019.


Social touch alters newborn monkey behavior.

Simpson EA, Maylott SE, Lazo RJ, Leonard KA, Kaburu SSK, Suomi SJ, Paukner A, Ferrari PF.

Infant Behav Dev. 2019 Nov;57:101368. doi: 10.1016/j.infbeh.2019.101368. Epub 2019 Sep 12.


Exploring the Needs of Adolescents With Sickle Cell Disease to Inform a Digital Self-Management and Transitional Care Program: Qualitative Study.

Kulandaivelu Y, Lalloo C, Ward R, Zempsky WT, Kirby-Allen M, Breakey VR, Odame I, Campbell F, Amaria K, Simpson EA, Nguyen C, George T, Stinson JN.

JMIR Pediatr Parent. 2018 Sep 25;1(2):e11058. doi: 10.2196/11058.


Face detection in 2- to 6-month-old infants is influenced by gaze direction and species.

Simpson EA, Maylott SE, Mitsven SG, Zeng G, Jakobsen KV.

Dev Sci. 2019 Sep 10:e12902. doi: 10.1111/desc.12902. [Epub ahead of print]


Validity and reliability of an online self-report 24-h dietary recall method (Intake24): a doubly labelled water study and repeated-measures analysis.

Foster E, Lee C, Imamura F, Hollidge SE, Westgate KL, Venables MC, Poliakov I, Rowland MK, Osadchiy T, Bradley JC, Simpson EL, Adamson AJ, Olivier P, Wareham N, Forouhi NG, Brage S.

J Nutr Sci. 2019 Aug 30;8:e29. doi: 10.1017/jns.2019.20. eCollection 2019.


A risk-based approach to cognitive bias in forensic science.

Camilleri A, Abarno D, Bird C, Coxon A, Mitchell N, Redman K, Sly N, Wills S, Silenieks E, Simpson E, Lindsay H.

Sci Justice. 2019 Sep;59(5):533-543. doi: 10.1016/j.scijus.2019.04.003. Epub 2019 Apr 30.


Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes.

Ozog S, Timberlake ND, Hermann K, Garijo O, Haworth KG, Shi G, Glinkerman CM, Schefter LE, D'Souza S, Simpson E, Sghia-Hughes G, Carillo RR, Boger DL, Kiem HP, Slukvin I, Ryu BY, Sorrentino BP, Adair JE, Snyder SA, Compton AA, Torbett BE.

Blood. 2019 Oct 17;134(16):1298-1311. doi: 10.1182/blood.2019000040.


Laboratory safety of dupilumab in moderate-to-severe atopic dermatitis: results from three phase III trials (LIBERTY AD SOLO 1, LIBERTY AD SOLO 2, LIBERTY AD CHRONOS).

Wollenberg A, Beck LA, Blauvelt A, Simpson EL, Chen Z, Chen Q, Shumel B, Khokhar FA, Hultsch T, Rizova E, Rossi AB, Graham NMH, Pirozzi G, Lu Y, Ardeleanu M.

Br J Dermatol. 2019 Aug 13. doi: 10.1111/bjd.18434. [Epub ahead of print]


Arid Climate Adipocere-The Importance of Microenvironment.

Byard RW, Simpson E, Forbes SL.

J Forensic Sci. 2019 Aug 9. doi: 10.1111/1556-4029.14152. [Epub ahead of print]


Alopecia areata in 2 patients treated with dupilumab: New onset and worsening.

Chung J, Slaught CL, Simpson EL.

JAAD Case Rep. 2019 Jul 30;5(8):643-645. doi: 10.1016/j.jdcr.2019.03.019. eCollection 2019 Aug. No abstract available.


Ferroportin-mediated iron export from vascular endothelial cells in retina and brain.

Baumann BH, Shu W, Song Y, Simpson EM, Lakhal-Littleton S, Dunaief JL.

Exp Eye Res. 2019 Oct;187:107728. doi: 10.1016/j.exer.2019.107728. Epub 2019 Jul 16.


Mechanisms Suppressing Superheavy Element Yields in Cold Fusion Reactions.

Banerjee K, Hinde DJ, Dasgupta M, Simpson EC, Jeung DY, Simenel C, Swinton-Bland BMA, Williams E, Carter IP, Cook KJ, David HM, Düllmann CE, Khuyagbaatar J, Kindler B, Lommel B, Prasad E, Sengupta C, Smith JF, Vo-Phuoc K, Walshe J, Yakushev A.

Phys Rev Lett. 2019 Jun 14;122(23):232503. doi: 10.1103/PhysRevLett.122.232503.


A randomized controlled trial of an emollient with ceramide and filaggrin-associated amino acids for the primary prevention of atopic dermatitis in high-risk infants.

McClanahan D, Wong A, Kezic S, Samrao A, Hajar T, Hill E, Simpson EL.

J Eur Acad Dermatol Venereol. 2019 Nov;33(11):2087-2094. doi: 10.1111/jdv.15786. Epub 2019 Jul 30.


Conceptual Model to Illustrate the Symptom Experience and Humanistic Burden Associated With Atopic Dermatitis in Adults and Adolescents.

Grant L, Seiding Larsen L, Trennery C, Silverberg JI, Abramovits W, Simpson EL, Stalder JF, Paty J, Hahn-Pedersen J, Kragh N, Bang B, Arbuckle R.

Dermatitis. 2019 Jul/Aug;30(4):247-254. doi: 10.1097/DER.0000000000000486.


Bone Marrow Transplantation 1957-2019.

Simpson E, Dazzi F.

Front Immunol. 2019 Jun 5;10:1246. doi: 10.3389/fimmu.2019.01246. eCollection 2019. Review.


Pain Is a Common and Burdensome Symptom of Atopic Dermatitis in United States Adults.

Silverberg JI, Gelfand JM, Margolis DJ, Boguniewicz M, Fonacier L, Grayson MH, Chiesa Fuxench ZC, Simpson EL, Ong PY.

J Allergy Clin Immunol Pract. 2019 Nov - Dec;7(8):2699-2706.e7. doi: 10.1016/j.jaip.2019.05.055. Epub 2019 Jun 20.


Immune-Mediated Neuropathies.

Fadia M, Shroff S, Simpson E.

Curr Treat Options Neurol. 2019 Jun 21;21(6):28. doi: 10.1007/s11940-019-0569-y. Review.


Emerging roles of striatal dopamine D2 receptors in motivated behaviour: Implications for psychiatric disorders.

Olivetti PR, Balsam PD, Simpson EH, Kellendonk C.

Basic Clin Pharmacol Toxicol. 2019 Jun 12. doi: 10.1111/bcpt.13271. [Epub ahead of print] Review.


Face detection in infants and adults: Effects of orientation and color.

Simpson EA, Maylott SE, Leonard K, Lazo RJ, Jakobsen KV.

J Exp Child Psychol. 2019 Oct;186:17-32. doi: 10.1016/j.jecp.2019.05.001. Epub 2019 Jun 8.


Dupilumab improves patient-reported symptoms of atopic dermatitis, symptoms of anxiety and depression, and health-related quality of life in moderate-to-severe atopic dermatitis: analysis of pooled data from the randomized trials SOLO 1 and SOLO 2.

Cork MJ, Eckert L, Simpson EL, Armstrong A, Barbarot S, Puig L, Girolomoni G, de Bruin-Weller M, Wollenberg A, Kataoka Y, Remitz A, Beissert S, Mastey V, Ardeleanu M, Chen Z, Gadkari A, Chao J.

J Dermatolog Treat. 2019 Jun 9:1-9. doi: 10.1080/09546634.2019.1612836. [Epub ahead of print]


Patient-reported outcomes of adalimumab, phototherapy, and placebo in the Vascular Inflammation in Psoriasis Trial: A randomized controlled study.

Noe MH, Wan MT, Shin DB, Armstrong AW, Duffin KC, Chiesa Fuxench ZC, Kalb RE, Menter A, Simpson EL, Takeshita J, Tyring SK, Van Voorhees AS, Mehta NN, Gelfand JM.

J Am Acad Dermatol. 2019 Oct;81(4):923-930. doi: 10.1016/j.jaad.2019.05.080. Epub 2019 Jun 1.


Kotatsu-induced erythema ab igne.

Baltazar D, Brockman R, Simpson E.

An Bras Dermatol. 2019 Mar-Apr;94(2):253-254. doi: 10.1590/abd1806-4841.20198792. Epub 2019 May 9. No abstract available.


Peer-led walking programme to increase physical activity in inactive 60- to 70-year-olds: Walk with Me pilot RCT.

Tully MA, Cunningham C, Wright A, McMullan I, Doherty J, Collins D, Tudor-Locke C, Morgan J, Phair G, Laventure B, Simpson EEA, McDonough SM, Gardner E, Kee F, Murphy MH, Agus A, Hunter RF, Hardeman W, Cupples ME.

Southampton (UK): NIHR Journals Library; 2019 May.


Infections in Dupilumab Clinical Trials in Atopic Dermatitis: A Comprehensive Pooled Analysis.

Eichenfield LF, Bieber T, Beck LA, Simpson EL, Thaçi D, de Bruin-Weller M, Deleuran M, Silverberg JI, Ferrandiz C, Fölster-Holst R, Chen Z, Graham NMH, Pirozzi G, Akinlade B, Yancopoulos GD, Ardeleanu M.

Am J Clin Dermatol. 2019 Jun;20(3):443-456. doi: 10.1007/s40257-019-00445-7.


Validation and Interpretation of Short Form 12 and Comparison with Dermatology Life Quality Index in Atopic Dermatitis in Adults.

Silverberg JI, Gelfand JM, Margolis DJ, Boguniewicz M, Fonacier L, Grayson MH, Ong PY, Chiesa Fuxench ZC, Simpson EL.

J Invest Dermatol. 2019 Oct;139(10):2090-2097.e3. doi: 10.1016/j.jid.2019.03.1152. Epub 2019 Apr 19.


Validation of five patient-reported outcomes for atopic dermatitis severity in adults.

Silverberg JI, Margolis DJ, Boguniewicz M, Fonacier L, Grayson MH, Ong PY, Fuxench ZC, Simpson EL.

Br J Dermatol. 2019 Apr 10. doi: 10.1111/bjd.18002. [Epub ahead of print]


Validation of a novel smartphone application-enabled, patient-operated skin barrier device.

Grinich EE, Shah AV, Simpson EL.

Skin Res Technol. 2019 Sep;25(5):612-617. doi: 10.1111/srt.12692. Epub 2019 Apr 3.


Origins of Incomplete Fusion Products and the Suppression of Complete Fusion in Reactions of ^{7}Li.

Cook KJ, Simpson EC, Bezzina LT, Dasgupta M, Hinde DJ, Banerjee K, Berriman AC, Sengupta C.

Phys Rev Lett. 2019 Mar 15;122(10):102501. doi: 10.1103/PhysRevLett.122.102501.


Rapid Integration of Zika Virus Prevention Within Sexual and Reproductive Health Services and Beyond: Programmatic Lessons From Latin America and the Caribbean.

Beare S, Simpson E, Gray K, Andjelic D.

Glob Health Sci Pract. 2019 Mar 29;7(1):116-127. doi: 10.9745/GHSP-D-18-00356. Print 2019 Mar 22.


Direct and Indirect Effects of Crisaborole Ointment on Quality of Life in Patients with Atopic Dermatitis: A Mediation Analysis.

Simpson EL, Yosipovitch G, Bushmakin AG, Cappelleri JC, Luger T, Ständer S, Tom WL, Ports WC, Zielinski MA, Tallman AM, Tan H, Gerber RA.

Acta Derm Venereol. 2019 Jul 1;99(9):756-761. doi: 10.2340/00015555-3181.


The effect of a randomized 12-week soy drink intervention on everyday mood in postmenopausal women.

Simpson EEA, Furlong ON, Parr HJ, Hodge SJ, Slevin MM, McSorley EM, McCormack JM, McConville C, Magee PJ.

Menopause. 2019 Aug;26(8):867-873. doi: 10.1097/GME.0000000000001322.


Distribution of atopic dermatitis lesions in United States adults.

Silverberg JI, Margolis DJ, Boguniewicz M, Fonacier L, Grayson MH, Ong PY, Chiesa Fuxench ZC, Simpson EL, Gelfand JM.

J Eur Acad Dermatol Venereol. 2019 Jul;33(7):1341-1348. doi: 10.1111/jdv.15574. Epub 2019 Apr 15.


Navigating the landscape of core outcome set development in dermatology.

Prinsen CAC, Spuls PI, Kottner J, Thomas KS, Apfelbacher C, Chalmers JR, Deckert S, Furue M, Gerbens L, Kirkham J, Simpson EL, Alam M, Balzer K, Beeckman D, Eleftheriadou V, Ezzedine K, Horbach SER, Ingram JR, Layton AM, Weller K, Wild T, Wolkerstorfer A, Williams HC, Schmitt J.

J Am Acad Dermatol. 2019 Jul;81(1):297-305. doi: 10.1016/j.jaad.2019.03.009. Epub 2019 Mar 13. Review.


Impact of Estrogens on the Regulation of White, Beige, and Brown Adipose Tissue Depots.

Bernasochi GB, Bell JR, Simpson ER, Delbridge LMD, Boon WC.

Compr Physiol. 2019 Mar 14;9(2):457-475. doi: 10.1002/cphy.c180009.


Consumption of a soy drink has no effect on cognitive function but may alleviate vasomotor symptoms in post-menopausal women; a randomised trial.

Furlong ON, Parr HJ, Hodge SJ, Slevin MM, Simpson EE, McSorley EM, McCormack JM, Magee PJ.

Eur J Nutr. 2019 Mar 12. doi: 10.1007/s00394-019-01942-5. [Epub ahead of print]


Conjunctivitis in dupilumab clinical trials.

Akinlade B, Guttman-Yassky E, de Bruin-Weller M, Simpson EL, Blauvelt A, Cork MJ, Prens E, Asbell P, Akpek E, Corren J, Bachert C, Hirano I, Weyne J, Korotzer A, Chen Z, Hultsch T, Zhu X, Davis JD, Mannent L, Hamilton JD, Teper A, Staudinger H, Rizova E, Pirozzi G, Graham NMH, Shumel B, Ardeleanu M, Wollenberg A.

Br J Dermatol. 2019 Sep;181(3):459-473. doi: 10.1111/bjd.17869. Epub 2019 May 7.

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