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Quantifying the contribution of intracranial pressure and arterial blood pressure to spontaneous tympanic membrane displacement.

El-Bouri WK, Vignali D, Iliadi K, Bulters DO, Marchbanks RJ, Birch AA, Simpson DM.

Physiol Meas. 2018 Jul 12. doi: 10.1088/1361-6579/aad308. [Epub ahead of print]


Stable isotope dynamic labeling of secretomes (SIDLS) identifies authentic secretory proteins released by cancer and stromal cells.

Hammond DE, Kumar JD, Raymond L, Simpson DM, Beynon RJ, Dockray GJ, Varro A.

Mol Cell Proteomics. 2018 Jun 18. pii: mcp.TIR117.000516. doi: 10.1074/mcp.TIR117.000516. [Epub ahead of print]


Evaluation of a novel chemokine receptor 2 (CCR2)-antagonist in painful diabetic polyneuropathy.

Kalliomäki J, Jonzon B, Huizar K, O'Malley M, Andersson A, Simpson DM.

Scand J Pain. 2013 Apr 1;4(2):77-83. doi: 10.1016/j.sjpain.2012.10.003.


Improved Detection of Vowel Envelope Frequency Following Responses Using Hotelling's T2 Analysis.

Vanheusden FJ, Bell SL, Chesnaye MA, Simpson DM.

Ear Hear. 2018 May 11. doi: 10.1097/AUD.0000000000000598. [Epub ahead of print]


Neuromuscular complications of HIV infection.

Kaku M, Simpson DM.

Handb Clin Neurol. 2018;152:201-212. doi: 10.1016/B978-0-444-63849-6.00016-5.


Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.

Apps JR, Carreno G, Gonzalez-Meljem JM, Haston S, Guiho R, Cooper JE, Manshaei S, Jani N, Hölsken A, Pettorini B, Beynon RJ, Simpson DM, Fraser HC, Hong Y, Hallang S, Stone TJ, Virasami A, Donson AM, Jones D, Aquilina K, Spoudeas H, Joshi AR, Grundy R, Storer LCD, Korbonits M, Hilton DA, Tossell K, Thavaraj S, Ungless MA, Gil J, Buslei R, Hankinson T, Hargrave D, Goding C, Andoniadou CL, Brogan P, Jacques TS, Williams HJ, Martinez-Barbera JP.

Acta Neuropathol. 2018 May;135(5):757-777. doi: 10.1007/s00401-018-1830-2. Epub 2018 Mar 14.


Objective measures for detecting the auditory brainstem response: comparisons of specificity, sensitivity and detection time.

Chesnaye MA, Bell SL, Harte JM, Simpson DM.

Int J Audiol. 2018 Jun;57(6):468-478. doi: 10.1080/14992027.2018.1447697. Epub 2018 Mar 14.


A comprehensive person-centered approach to adult spastic paresis: a consensus-based framework.

Turner-Stokes L, Ashford S, Esquenazi A, Wissel J, Ward AB, Francisco G, Lains J, Suputtitada A, Serrano S, Baguley IJ, Barnes M, Simpson DM.

Eur J Phys Rehabil Med. 2018 Aug;54(4):605-617. doi: 10.23736/S1973-9087.17.04808-0. Epub 2017 Dec 21.


NaV channel variants in patients with painful and nonpainful peripheral neuropathy.

Wadhawan S, Pant S, Golhar R, Kirov S, Thompson J, Jacobsen L, Qureshi I, Ajroud-Driss S, Freeman R, Simpson DM, Smith AG, Hoke A, Bristow LJ.

Neurol Genet. 2017 Dec 15;3(6):e207. doi: 10.1212/NXG.0000000000000207. eCollection 2017 Dec.


The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks.

Clarke K, Ricciardi S, Pearson T, Bharudin I, Davidsen PK, Bonomo M, Brina D, Scagliola A, Simpson DM, Beynon RJ, Khanim F, Ankers J, Sarzynski MA, Ghosh S, Pisconti A, Rozman J, Hrabe de Angelis M, Bunce C, Stewart C, Egginton S, Caddick M, Jackson M, Bouchard C, Biffo S, Falciani F.

Cell Rep. 2017 Nov 7;21(6):1507-1520. doi: 10.1016/j.celrep.2017.10.040.


HIV, antiretrovirals, and peripheral neuropathy: A moving target.

Kaku M, Simpson DM.

Muscle Nerve. 2018 Mar;57(3):347-349. doi: 10.1002/mus.25990. Epub 2017 Dec 22. No abstract available.


Coherent averaging of pseudorandom binary stimuli: is the dynamic cerebral autoregulatory response symmetrical?

Katsogridakis E, Simpson DM, Bush G, Fan L, Birch AA, Allen R, Potter JF, Panerai RB.

Physiol Meas. 2017 Nov 30;38(12):2164-2175. doi: 10.1088/1361-6579/aa9086.


Estimation of confidence limits for descriptive indexes derived from autoregressive analysis of time series: Methods and application to heart rate variability.

Beda A, Simpson DM, Faes L.

PLoS One. 2017 Oct 2;12(10):e0183230. doi: 10.1371/journal.pone.0183230. eCollection 2017.


Glareosin: a novel sexually dimorphic urinary lipocalin in the bank vole, Myodes glareolus.

Loxley GM, Unsworth J, Turton MJ, Jebb A, Lilley KS, Simpson DM, Rigden DJ, Hurst JL, Beynon RJ.

Open Biol. 2017 Sep;7(9). pii: 170135. doi: 10.1098/rsob.170135.


Learning About Love: A Meta-Analytic Study of Individually-Oriented Relationship Education Programs for Adolescents and Emerging Adults.

Simpson DM, Leonhardt ND, Hawkins AJ.

J Youth Adolesc. 2018 Mar;47(3):477-489. doi: 10.1007/s10964-017-0725-1. Epub 2017 Aug 16.


Directional connectivity in the EEG is able to discriminate wakefulness from NREM sleep.

Lioi G, Bell SL, Smith DC, Simpson DM.

Physiol Meas. 2017 Aug 22;38(9):1802-1820. doi: 10.1088/1361-6579/aa81b5.


Increased blood pressure variability upon standing up improves reproducibility of cerebral autoregulation indices.

Mahdi A, Nikolic D, Birch AA, Olufsen MS, Panerai RB, Simpson DM, Payne SJ.

Med Eng Phys. 2017 Sep;47:151-158. doi: 10.1016/j.medengphy.2017.06.006. Epub 2017 Jul 8.


Autologous chondrocyte implantation-derived synovial fluids display distinct responder and non-responder proteomic profiles.

Hulme CH, Wilson EL, Peffers MJ, Roberts S, Simpson DM, Richardson JB, Gallacher P, Wright KT.

Arthritis Res Ther. 2017 Jun 30;19(1):150. doi: 10.1186/s13075-017-1336-7.


Biokinetic Analysis and Metabolic Fate of 2,4-D in 2,4-D-Resistant Soybean (Glycine max).

Skelton JJ, Simpson DM, Peterson MA, Riechers DE.

J Agric Food Chem. 2017 Jul 26;65(29):5847-5859. doi: 10.1021/acs.jafc.7b00796. Epub 2017 Jul 14.


Dose-Dependent Effects of AbobotulinumtoxinA (Dysport) on Spasticity and Active Movements in Adults With Upper Limb Spasticity: Secondary Analysis of a Phase 3 Study.

O'Dell MW, Brashear A, Jech R, Lejeune T, Marque P, Bensmail D, Ayyoub Z, Simpson DM, Volteau M, Vilain C, Picaut P, Gracies JM.

PM R. 2018 Jan;10(1):1-10. doi: 10.1016/j.pmrj.2017.06.008. Epub 2017 Jun 19.


Direct characterization of the native structure and mechanics of cyanobacterial carboxysomes.

Faulkner M, Rodriguez-Ramos J, Dykes GF, Owen SV, Casella S, Simpson DM, Beynon RJ, Liu LN.

Nanoscale. 2017 Aug 3;9(30):10662-10673. doi: 10.1039/c7nr02524f.


Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study.

Jia P, Zhao Z, Hulgan T, Bush WS, Samuels DC, Bloss CS, Heaton RK, Ellis RJ, Schork N, Marra CM, Collier AC, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, McCutchan JA, Barnholtz-Sloan JS, Franklin DR, Rosario D, Letendre SL, Grant I, Kallianpur AR; CHARTER Study Group.

Am J Med Genet B Neuropsychiatr Genet. 2017 Jun;174(4):413-426. doi: 10.1002/ajmg.b.32530. Epub 2017 Apr 26.


Predictive control of intersegmental tarsal movements in an insect.

Costalago-Meruelo A, Simpson DM, Veres SM, Newland PL.

J Comput Neurosci. 2017 Aug;43(1):5-15. doi: 10.1007/s10827-017-0644-x. Epub 2017 Apr 22.


DOSCATs: Double standards for protein quantification.

Bennett RJ, Simpson DM, Holman SW, Ryan S, Brownridge P, Eyers CE, Colyer J, Beynon RJ.

Sci Rep. 2017 Apr 3;7:45570. doi: 10.1038/srep45570.


OnabotulinumtoxinA for Lower Limb Spasticity: Guidance From a Delphi Panel Approach.

Esquenazi A, Alfaro A, Ayyoub Z, Charles D, Dashtipour K, Graham GD, McGuire JR, Odderson IR, Patel AT, Simpson DM.

PM R. 2017 Oct;9(10):960-968. doi: 10.1016/j.pmrj.2017.02.014. Epub 2017 Mar 7. Review.


Safety and efficacy of incobotulinumtoxinA doses up to 800 U in limb spasticity: The TOWER study.

Wissel J, Bensmail D, Ferreira JJ, Molteni F, Satkunam L, Moraleda S, Rekand T, McGuire J, Scheschonka A, Flatau-Baqué B, Simon O, Rochford ET, Dressler D, Simpson DM; TOWER study investigators.

Neurology. 2017 Apr 4;88(14):1321-1328. doi: 10.1212/WNL.0000000000003789. Epub 2017 Mar 10.


Prevalence and Correlates of Persistent HIV-1 RNA in Cerebrospinal Fluid During Antiretroviral Therapy.

Anderson AM, Muñoz-Moreno JA, McClernon DR, Ellis RJ, Cookson D, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Sacktor N, Simpson DM, Franklin DR, Heaton RK, Grant I, Letendre SL; CHARTER Group.

J Infect Dis. 2017 Jan 1;215(1):105-113. doi: 10.1093/infdis/jiw505. Epub 2016 Oct 26.


Capsaicin 8% Patch in Painful Diabetic Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Study.

Simpson DM, Robinson-Papp J, Van J, Stoker M, Jacobs H, Snijder RJ, Schregardus DS, Long SK, Lambourg B, Katz N.

J Pain. 2017 Jan;18(1):42-53. doi: 10.1016/j.jpain.2016.09.008. Epub 2016 Oct 13.


Assessment of autonomic symptoms in a medically complex, urban patient population.

Robinson-Papp J, Sharma SK, George MC, Simpson DM.

Clin Auton Res. 2017 Feb;27(1):25-29. doi: 10.1007/s10286-016-0384-4. Epub 2016 Oct 12.


Poster 371 Escalating Doses of IncobotulinumtoxinA (400-800U) Are Well Tolerated and Lead to Increasing Improvements in Disability Due to Multifocal Upper- and Lower-Limb Spasticity.

Wissel J, Bensmail D, McGuire JR, Rubin BS, Scheschonka A, Simon O, Simpson DM.

PM R. 2016 Sep;8(9S):S282. doi: 10.1016/j.pmrj.2016.07.298. Epub 2016 Sep 24. No abstract available.


Poster 354 OnabotulinumtoxinA to Treat Common Postures in Post-Stroke Lower Limb Spasticity: Identification of a Treatment Paradigm.

Esquenazi A, Dashtipour K, Alfaro A, Ayyoub Z, Charles D, Graham GD, McGuire JR, Odderson IR, Patel AT, Simpson DM.

PM R. 2016 Sep;8(9S):S276. doi: 10.1016/j.pmrj.2016.07.523. Epub 2016 Sep 24. No abstract available.


Poster 308 Improvement of Spasticity, Active Movements and Active Function after Repeated Injections of AbobotulinumtoxinA (Dysport) in Adults with Spastic Paresis in the Upper Limb: Results of a Phase III Open-Label Extension Study.

Marciniak C, Gul F, Ayyoub Z, Simpson DM, Walker HW, Wimmer M, Vilain C, Graciès JM.

PM R. 2016 Sep;8(9S):S260. doi: 10.1016/j.pmrj.2016.07.479. Epub 2016 Sep 24. No abstract available.


Protein turnover measurement using selected reaction monitoring-mass spectrometry (SRM-MS).

Holman SW, Hammond DE, Simpson DM, Waters J, Hurst JL, Beynon RJ.

Philos Trans A Math Phys Eng Sci. 2016 Oct 28;374(2079). pii: 20150362. doi: 10.1098/rsta.2015.0362.


OnabotulinumtoxinA Injection for Poststroke Upper-Limb Spasticity: Guidance for Early Injectors From a Delphi Panel Process.

Simpson DM, Patel AT, Alfaro A, Ayyoub Z, Charles D, Dashtipour K, Esquenazi A, Graham GD, McGuire JR, Odderson I.

PM R. 2017 Feb;9(2):136-148. doi: 10.1016/j.pmrj.2016.06.016. Epub 2016 Jun 23.


Revisiting the frequency domain: the multiple and partial coherence of cerebral blood flow velocity in the assessment of dynamic cerebral autoregulation.

Katsogridakis E, Simpson DM, Bush G, Fan L, Birch AA, Allen R, Potter JF, Panerai RB.

Physiol Meas. 2016 Jul;37(7):1056-73. doi: 10.1088/0967-3334/37/7/1056. Epub 2016 May 31.


Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation.

Arecco N, Clarke CJ, Jones FK, Simpson DM, Mason D, Beynon RJ, Pisconti A.

Sci Rep. 2016 May 31;6:24708. doi: 10.1038/srep24708.


Practice guideline update summary: Botulinum neurotoxin for the treatment of blepharospasm, cervical dystonia, adult spasticity, and headache: Report of the Guideline Development Subcommittee of the American Academy of Neurology.

Simpson DM, Hallett M, Ashman EJ, Comella CL, Green MW, Gronseth GS, Armstrong MJ, Gloss D, Potrebic S, Jankovic J, Karp BP, Naumann M, So YT, Yablon SA.

Neurology. 2016 May 10;86(19):1818-26. doi: 10.1212/WNL.0000000000002560. Epub 2016 Apr 18.


Patient reported outcome measures of pain intensity: Do they tell us what we need to know?

Dorfman D, George MC, Robinson-Papp J, Rahman T, Tamler R, Simpson DM.

Scand J Pain. 2016 Apr;11:73-76. doi: 10.1016/j.sjpain.2015.12.004. Epub 2016 Jan 9.


Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity.

Kaku M, Simpson DM.

Drug Des Devel Ther. 2016 Mar 8;10:1085-99. doi: 10.2147/DDDT.S80804. eCollection 2016. Review.


Apolipoprotein E ε4 genotype status is not associated with neuroimaging outcomes in a large cohort of HIV+ individuals.

Cooley SA, Paul RH, Fennema-Notestine C, Morgan EE, Vaida F, Deng Q, Chen JA, Letendre S, Ellis R, Clifford DB, Marra CM, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Simpson DM, Morgello S, Grant I, Ances BM; CNS HIV Anti-Retroviral Therapy Effects Research (CHARTER) Group.

J Neurovirol. 2016 Oct;22(5):607-614. Epub 2016 Mar 28.


Proteome Dynamics: Tissue Variation in the Kinetics of Proteostasis in Intact Animals.

Hammond DE, Claydon AJ, Simpson DM, Edward D, Stockley P, Hurst JL, Beynon RJ.

Mol Cell Proteomics. 2016 Apr;15(4):1204-19. doi: 10.1074/mcp.M115.053488. Epub 2016 Feb 1.


Transfer function analysis of dynamic cerebral autoregulation: A white paper from the International Cerebral Autoregulation Research Network.

Claassen JA, Meel-van den Abeelen AS, Simpson DM, Panerai RB; international Cerebral Autoregulation Research Network (CARNet).

J Cereb Blood Flow Metab. 2016 Apr;36(4):665-80. doi: 10.1177/0271678X15626425. Epub 2016 Jan 18. Review.


Assessing cerebral blood flow control from variability in blood pressure and arterial CO2 levels.

Nikolić D, Birch AA, Panerai RB, Simpson DM.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:1785-8. doi: 10.1109/EMBC.2015.7318725.


Persistent CSF but not plasma HIV RNA is associated with increased risk of new-onset moderate-to-severe depressive symptoms; a prospective cohort study.

Hammond ER, Crum RM, Treisman GJ, Mehta SH, Clifford DB, Ellis RJ, Gelman BB, Grant I, Letendre SL, Marra CM, Morgello S, Simpson DM, Mcarthur JC; CHARTER Group.

J Neurovirol. 2016 Aug;22(4):479-87. doi: 10.1007/s13365-015-0416-1. Epub 2016 Jan 4.


Improved system identification using artificial neural networks and analysis of individual differences in responses of an identified neuron.

Costalago Meruelo A, Simpson DM, Veres SM, Newland PL.

Neural Netw. 2016 Mar;75:56-65. doi: 10.1016/j.neunet.2015.12.002. Epub 2015 Dec 9.


Anemia and Red Blood Cell Indices Predict HIV-Associated Neurocognitive Impairment in the Highly Active Antiretroviral Therapy Era.

Kallianpur AR, Wang Q, Jia P, Hulgan T, Zhao Z, Letendre SL, Ellis RJ, Heaton RK, Franklin DR, Barnholtz-Sloan J, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Grant I; CHARTER Study Group.

J Infect Dis. 2016 Apr 1;213(7):1065-73. doi: 10.1093/infdis/jiv754. Epub 2015 Dec 21.


Chronic pain disorders in HIV primary care: clinical characteristics and association with healthcare utilization.

Jiao JM, So E, Jebakumar J, George MC, Simpson DM, Robinson-Papp J.

Pain. 2016 Apr;157(4):931-7. doi: 10.1097/j.pain.0000000000000462.


Lower CSF Aβ is Associated with HAND in HIV-Infected Adults with a Family History of Dementia.

Fazeli PL, Moore DJ, Franklin DR, Umlauf A, Heaton RK, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor NC, Morgello S, Simpson DM, McCutchan JA, Grant I, Letendre SL.

Curr HIV Res. 2016;14(4):324-30.


Dalfampridine in chronic sensorimotor deficits after ischemic stroke: A proof of concept study.

Simpson DM, Goldenberg J, Kasner S, Nash M, Reding MJ, Zweifler RM, Suarez G, Zhao P, Henney HR III, Rabinowicz AL, Carrazana E.

J Rehabil Med. 2015 Nov;47(10):924-31. doi: 10.2340/16501977-2033.

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