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Pathways, Processes, and Candidate Drugs Associated with a Hoxa Cluster-Dependency Model of Leukemia.

Kettyle LM, Lebert-Ghali CÉ, Grishagin IV, Dickson GJ, O'Reilly PG, Simpson DA, Bijl JJ, Mills KI, Sauvageau G, Thompson A.

Cancers (Basel). 2019 Dec 17;11(12). pii: E2036. doi: 10.3390/cancers11122036.


Genetic determinants of cellular addiction to DNA polymerase theta.

Feng W, Simpson DA, Carvajal-Garcia J, Price BA, Kumar RJ, Mose LE, Wood RD, Rashid N, Purvis JE, Parker JS, Ramsden DA, Gupta GP.

Nat Commun. 2019 Sep 19;10(1):4286. doi: 10.1038/s41467-019-12234-1.


Differential Expression of Urinary Exosomal MicroRNAs miR-21-5p and miR-30b-5p in Individuals with Diabetic Kidney Disease.

Zang J, Maxwell AP, Simpson DA, McKay GJ.

Sci Rep. 2019 Jul 29;9(1):10900. doi: 10.1038/s41598-019-47504-x.


A comparison of RNA extraction and sequencing protocols for detection of small RNAs in plasma.

Wong RKY, MacMahon M, Woodside JV, Simpson DA.

BMC Genomics. 2019 Jun 3;20(1):446. doi: 10.1186/s12864-019-5826-7.


Microscopic Imaging of the Stress Tensor in Diamond Using in Situ Quantum Sensors.

Broadway DA, Johnson BC, Barson MSJ, Lillie SE, Dontschuk N, McCloskey DJ, Tsai A, Teraji T, Simpson DA, Stacey A, McCallum JC, Bradby JE, Doherty MW, Hollenberg LCL, Tetienne JP.

Nano Lett. 2019 Jul 10;19(7):4543-4550. doi: 10.1021/acs.nanolett.9b01402. Epub 2019 Jun 12.


RAG2 localization and dynamics in the pre-B cell nucleus.

Rodgers W, Byrum JN, Simpson DA, Hoolehan W, Rodgers KK.

PLoS One. 2019 May 10;14(5):e0216137. doi: 10.1371/journal.pone.0216137. eCollection 2019.


Quantum Sensing in a Physiological-Like Cell Niche Using Fluorescent Nanodiamonds Embedded in Electrospun Polymer Nanofibers.

Price JC, Levett SJ, Radu V, Simpson DA, Barcons AM, Adams CF, Mather ML.

Small. 2019 May;15(22):e1900455. doi: 10.1002/smll.201900455. Epub 2019 Apr 22.


Rapid, High-Resolution Magnetic Microscopy of Single Magnetic Microbeads.

McCoey JM, de Gille RW, Nasr B, Tetienne JP, Hall LT, Simpson DA, Hollenberg LCL.

Small. 2019 May;15(18):e1805159. doi: 10.1002/smll.201805159. Epub 2019 Mar 26.


Twenty-five-year trends in breastfeeding initiation: The effects of sociodemographic changes in Great Britain, 1985-2010.

Simpson DA, Quigley MA, Kurinczuk JJ, Carson C.

PLoS One. 2019 Jan 17;14(1):e0210838. doi: 10.1371/journal.pone.0210838. eCollection 2019. Erratum in: PLoS One. 2019 Feb 7;14(2):e0212301.


Proximity-Induced Artefacts in Magnetic Imaging with Nitrogen-Vacancy Ensembles in Diamond.

Tetienne JP, Broadway DA, Lillie SE, Dontschuk N, Teraji T, Hall LT, Stacey A, Simpson DA, Hollenberg LCL.

Sensors (Basel). 2018 Apr 23;18(4). pii: E1290. doi: 10.3390/s18041290.


Quantum probe hyperpolarisation of molecular nuclear spins.

Broadway DA, Tetienne JP, Stacey A, Wood JDA, Simpson DA, Hall LT, Hollenberg LCL.

Nat Commun. 2018 Mar 28;9(1):1246. doi: 10.1038/s41467-018-03578-1.


Impact of Surface Functionalization on the Quantum Coherence of Nitrogen-Vacancy Centers in Nanodiamonds.

Ryan RG, Stacey A, O'Donnell KM, Ohshima T, Johnson BC, Hollenberg LCL, Mulvaney P, Simpson DA.

ACS Appl Mater Interfaces. 2018 Apr 18;10(15):13143-13149. doi: 10.1021/acsami.7b19238. Epub 2018 Apr 5.


Magnetically sensitive nanodiamond-doped tellurite glass fibers.

Ruan Y, Simpson DA, Jeske J, Ebendorff-Heidepriem H, Lau DWM, Ji H, Johnson BC, Ohshima T, Afshar V S, Hollenberg L, Greentree AD, Monro TM, Gibson BC.

Sci Rep. 2018 Jan 19;8(1):1268. doi: 10.1038/s41598-018-19400-3.


Non-Neurotoxic Nanodiamond Probes for Intraneuronal Temperature Mapping.

Simpson DA, Morrisroe E, McCoey JM, Lombard AH, Mendis DC, Treussart F, Hall LT, Petrou S, Hollenberg LCL.

ACS Nano. 2017 Dec 26;11(12):12077-12086. doi: 10.1021/acsnano.7b04850. Epub 2017 Nov 13.


Electron paramagnetic resonance microscopy using spins in diamond under ambient conditions.

Simpson DA, Ryan RG, Hall LT, Panchenko E, Drew SC, Petrou S, Donnelly PS, Mulvaney P, Hollenberg LCL.

Nat Commun. 2017 Sep 6;8(1):458. doi: 10.1038/s41467-017-00466-y.


Microwave-free nuclear magnetic resonance at molecular scales.

Wood JDA, Tetienne JP, Broadway DA, Hall LT, Simpson DA, Stacey A, Hollenberg LCL.

Nat Commun. 2017 Jul 3;8:15950. doi: 10.1038/ncomms15950.


Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells.

Bower JJ, Vance LD, Psioda M, Smith-Roe SL, Simpson DA, Ibrahim JG, Hoadley KA, Perou CM, Kaufmann WK.

NPJ Breast Cancer. 2017 Mar 31;3:9. doi: 10.1038/s41523-017-0009-7. eCollection 2017.


MicroRNA-containing extracellular vesicles released from endothelial colony-forming cells modulate angiogenesis during ischaemic retinopathy.

Dellett M, Brown ED, Guduric-Fuchs J, O'Connor A, Stitt AW, Medina RJ, Simpson DA.

J Cell Mol Med. 2017 Dec;21(12):3405-3419. doi: 10.1111/jcmm.13251. Epub 2017 Jun 20.


Quantum imaging of current flow in graphene.

Tetienne JP, Dontschuk N, Broadway DA, Stacey A, Simpson DA, Hollenberg LCL.

Sci Adv. 2017 Apr 26;3(4):e1602429. doi: 10.1126/sciadv.1602429. eCollection 2017 Apr.


Environmentally Mediated Coherent Control of a Spin Qubit in Diamond.

Lillie SE, Broadway DA, Wood JDA, Simpson DA, Stacey A, Tetienne JP, Hollenberg LCL.

Phys Rev Lett. 2017 Apr 21;118(16):167204. doi: 10.1103/PhysRevLett.118.167204. Epub 2017 Apr 19.


RNA-Sequencing data supports the existence of novel VEGFA splicing events but not of VEGFAxxxb isoforms.

Bridgett S, Dellett M, Simpson DA.

Sci Rep. 2017 Mar 3;7(1):58. doi: 10.1038/s41598-017-00100-3.


Nanomechanical Sensing Using Spins in Diamond.

Barson MS, Peddibhotla P, Ovartchaiyapong P, Ganesan K, Taylor RL, Gebert M, Mielens Z, Koslowski B, Simpson DA, McGuinness LP, McCallum J, Prawer S, Onoda S, Ohshima T, Bleszynski Jayich AC, Jelezko F, Manson NB, Doherty MW.

Nano Lett. 2017 Mar 8;17(3):1496-1503. doi: 10.1021/acs.nanolett.6b04544. Epub 2017 Feb 13.


TRPV2 Channels Contribute to Stretch-Activated Cation Currents and Myogenic Constriction in Retinal Arterioles.

McGahon MK, Fernández JA, Dash DP, McKee J, Simpson DA, Zholos AV, McGeown JG, Curtis TM.

Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5637-5647. doi: 10.1167/iovs.16-20279.


Magneto-optical imaging of thin magnetic films using spins in diamond.

Simpson DA, Tetienne JP, McCoey JM, Ganesan K, Hall LT, Petrou S, Scholten RE, Hollenberg LC.

Sci Rep. 2016 Mar 14;6:22797. doi: 10.1038/srep22797.


Considerations for optimization of microRNA PCR assays for molecular diagnosis.

Dellett M, Simpson DA.

Expert Rev Mol Diagn. 2016;16(4):407-14. doi: 10.1586/14737159.2016.1152184. Epub 2016 Feb 29. Review.


Intrinsic fluorescence of selenium nanoparticles for cellular imaging applications.

Khalid A, Tran PA, Norello R, Simpson DA, O'Connor AJ, Tomljenovic-Hanic S.

Nanoscale. 2016 Feb 14;8(6):3376-85. doi: 10.1039/c5nr08771f.


Detection of nanoscale electron spin resonance spectra demonstrated using nitrogen-vacancy centre probes in diamond.

Hall LT, Kehayias P, Simpson DA, Jarmola A, Stacey A, Budker D, Hollenberg LC.

Nat Commun. 2016 Jan 5;7:10211. doi: 10.1038/ncomms10211.


Scanning Nanospin Ensemble Microscope for Nanoscale Magnetic and Thermal Imaging.

Tetienne JP, Lombard A, Simpson DA, Ritchie C, Lu J, Mulvaney P, Hollenberg LC.

Nano Lett. 2016 Jan 13;16(1):326-33. doi: 10.1021/acs.nanolett.5b03877. Epub 2016 Jan 4.


Effective intra-S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines.

Cordeiro-Stone M, McNulty JJ, Sproul CD, Chastain PD, Gibbs-Flournoy E, Zhou Y, Carson C, Rao S, Mitchell DL, Simpson DA, Thomas NE, Ibrahim JG, Kaufmann WK.

Pigment Cell Melanoma Res. 2016 Jan;29(1):68-80. doi: 10.1111/pcmr.12426. Epub 2015 Nov 3.


Guidelines for ethical behavior relating to clinical practice issues in neuromuscular and electrodiagnostic medicine.

Abel NA, De Sousa EA, Govindarajan R, Mayer MP, Simpson DA.

Muscle Nerve. 2015 Dec;52(6):1122-9. doi: 10.1002/mus.24910. Epub 2015 Oct 10.


Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity.

Simpson DA, Lemonie N, Morgan DS, Gaddameedhi S, Kaufmann WK.

Cancers (Basel). 2015 Jun 17;7(2):1072-90. doi: 10.3390/cancers7020825.


SWI/SNF complexes are required for full activation of the DNA-damage response.

Smith-Roe SL, Nakamura J, Holley D, Chastain PD 2nd, Rosson GB, Simpson DA, Ridpath JR, Kaufman DG, Kaufmann WK, Bultman SJ.

Oncotarget. 2015 Jan 20;6(2):732-45.


Small RNAs from plants, bacteria and fungi within the order Hypocreales are ubiquitous in human plasma.

Beatty M, Guduric-Fuchs J, Brown E, Bridgett S, Chakravarthy U, Hogg RE, Simpson DA.

BMC Genomics. 2014 Oct 25;15:933. doi: 10.1186/1471-2164-15-933.


Mutational Analysis of the Rhodopsin Gene in Sector Retinitis Pigmentosa.

Napier ML, Durga D, Wolsley CJ, Chamney S, Alexander S, Brennan R, Simpson DA, Silvestri G, Willoughby CE.

Ophthalmic Genet. 2015;36(3):239-43. doi: 10.3109/13816810.2014.958862.


Whole-mitochondrial genome sequencing in primary open-angle glaucoma using massively parallel sequencing identifies novel and known pathogenic variants.

Sundaresan P, Simpson DA, Sambare C, Duffy S, Lechner J, Dastane A, Dervan EW, Vallabh N, Chelerkar V, Deshpande M, O'Brien C, McKnight AJ, Willoughby CE.

Genet Med. 2015 Apr;17(4):279-84. doi: 10.1038/gim.2014.121. Epub 2014 Sep 18.


A global database of C4 photosynthesis in grasses.

Osborne CP, Salomaa A, Kluyver TA, Visser V, Kellogg EA, Morrone O, Vorontsova MS, Clayton WD, Simpson DA.

New Phytol. 2014 Nov;204(3):441-6. doi: 10.1111/nph.12942. Epub 2014 Jul 21. No abstract available.


Enrichment of pathogenic alleles in the brittle cornea gene, ZNF469, in keratoconus.

Lechner J, Porter LF, Rice A, Vitart V, Armstrong DJ, Schorderet DF, Munier FL, Wright AF, Inglehearn CF, Black GC, Simpson DA, Manson F, Willoughby CE.

Hum Mol Genet. 2014 Oct 15;23(20):5527-35. doi: 10.1093/hmg/ddu253. Epub 2014 Jun 3.


In vivo imaging and tracking of individual nanodiamonds in drosophila melanogaster embryos.

Simpson DA, Thompson AJ, Kowarsky M, Zeeshan NF, Barson MS, Hall LT, Yan Y, Kaufmann S, Johnson BC, Ohshima T, Caruso F, Scholten RE, Saint RB, Murray MJ, Hollenberg LC.

Biomed Opt Express. 2014 Mar 20;5(4):1250-61. doi: 10.1364/BOE.5.001250. eCollection 2014 Apr 1.


Mechanisms of chromosomal instability in melanoma.

Kaufmann WK, Carson CC, Omolo B, Filgo AJ, Sambade MJ, Simpson DA, Shields JM, Ibrahim JG, Thomas NE.

Environ Mol Mutagen. 2014 Jul;55(6):457-71. doi: 10.1002/em.21859. Epub 2014 Feb 24.


Electronic properties and metrology applications of the diamond NV- center under pressure.

Doherty MW, Struzhkin VV, Simpson DA, McGuinness LP, Meng Y, Stacey A, Karle TJ, Hemley RJ, Manson NB, Hollenberg LC, Prawer S.

Phys Rev Lett. 2014 Jan 31;112(4):047601. Epub 2014 Jan 31.


Rapid quantification of microRNAs in plasma using a fast real-time PCR system.

Andrews WJ, Brown ED, Dellett M, Hogg RE, Simpson DA.

Biotechniques. 2015 May 1;58(5):244-52. doi: 10.2144/000114287. eCollection 2015 May.


Extremely complex populations of small RNAs in the mouse retina and RPE/choroid.

Soundara Pandi SP, Chen M, Guduric-Fuchs J, Xu H, Simpson DA.

Invest Ophthalmol Vis Sci. 2013 Dec 17;54(13):8140-51. doi: 10.1167/iovs.13-12631.


Next generation sequencing-based molecular diagnosis of retinitis pigmentosa: identification of a novel genotype-phenotype correlation and clinical refinements.

Wang F, Wang H, Tuan HF, Nguyen DH, Sun V, Keser V, Bowne SJ, Sullivan LS, Luo H, Zhao L, Wang X, Zaneveld JE, Salvo JS, Siddiqui S, Mao L, Wheaton DK, Birch DG, Branham KE, Heckenlively JR, Wen C, Flagg K, Ferreyra H, Pei J, Khan A, Ren H, Wang K, Lopez I, Qamar R, Zenteno JC, Ayala-Ramirez R, Buentello-Volante B, Fu Q, Simpson DA, Li Y, Sui R, Silvestri G, Daiger SP, Koenekoop RK, Zhang K, Chen R.

Hum Genet. 2014 Mar;133(3):331-45. doi: 10.1007/s00439-013-1381-5. Epub 2013 Oct 24.


Gene expression signatures but not cell cycle checkpoint functions distinguish AT carriers from normal individuals.

Zhang L, Simpson DA, Innes CL, Chou J, Bushel PR, Paules RS, Kaufmann WK, Zhou T.

Physiol Genomics. 2013 Oct 1;45(19):907-16. doi: 10.1152/physiolgenomics.00064.2013. Epub 2013 Aug 13.


Mutational analysis of MIR184 in sporadic keratoconus and myopia.

Lechner J, Bae HA, Guduric-Fuchs J, Rice A, Govindarajan G, Siddiqui S, Abi Farraj L, Yip SP, Yap M, Das M, Souzeau E, Coster D, Mills RA, Lindsay R, Phillips T, Mitchell P, Ali M, Inglehearn CF, Sundaresan P, Craig JE, Simpson DA, Burdon KP, Willoughby CE.

Invest Ophthalmol Vis Sci. 2013 Aug 5;54(8):5266-72. doi: 10.1167/iovs.13-12035.


Distinctive profile of IsomiR expression and novel microRNAs in rat heart left ventricle.

McGahon MK, Yarham JM, Daly A, Guduric-Fuchs J, Ferguson LJ, Simpson DA, Collins A.

PLoS One. 2013 Jun 14;8(6):e65809. doi: 10.1371/journal.pone.0065809. Print 2013.


Detection of atomic spin labels in a lipid bilayer using a single-spin nanodiamond probe.

Kaufmann S, Simpson DA, Hall LT, Perunicic V, Senn P, Steinert S, McGuinness LP, Johnson BC, Ohshima T, Caruso F, Wrachtrup J, Scholten RE, Mulvaney P, Hollenberg L.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):10894-8. doi: 10.1073/pnas.1300640110. Epub 2013 Jun 17.


Ex vivo expansion of human outgrowth endothelial cells leads to IL-8-mediated replicative senescence and impaired vasoreparative function.

Medina RJ, O'Neill CL, O'Doherty TM, Chambers SE, Guduric-Fuchs J, Neisen J, Waugh DJ, Simpson DA, Stitt AW.

Stem Cells. 2013 Aug;31(8):1657-68. doi: 10.1002/stem.1414.


Mutational spectrum of the ZEB1 gene in corneal dystrophies supports a genotype-phenotype correlation.

Lechner J, Dash DP, Muszynska D, Hosseini M, Segev F, George S, Frazer DG, Moore JE, Kaye SB, Young T, Simpson DA, Churchill AJ, Héon E, Willoughby CE.

Invest Ophthalmol Vis Sci. 2013 May 3;54(5):3215-23. doi: 10.1167/iovs.13-11781.


A prognostic signature of G(2) checkpoint function in melanoma cell lines.

Omolo B, Carson C, Chu H, Zhou Y, Simpson DA, Hesse JE, Paules RS, Nyhan KC, Ibrahim JG, Kaufmann WK.

Cell Cycle. 2013 Apr 1;12(7):1071-82. doi: 10.4161/cc.24067. Epub 2013 Mar 1.

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