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The impact of acute and chronic exercise on Nrf2 expression in relation to markers of mitochondrial biogenesis in human skeletal muscle.

Islam H, Bonafiglia JT, Turnbull PC, Simpson CA, Perry CGR, Gurd BJ.

Eur J Appl Physiol. 2019 Nov 9. doi: 10.1007/s00421-019-04259-7. [Epub ahead of print]


The filaggrin gene mutation, atopic dermatitis and asthma.

Simpson CR, Sheikh A.

Prim Care Respir J. 2007 Oct;16(5):322-323. doi: 10.3132/pcrj.2007.00065. Epub 2007 Oct 12. No abstract available.


Corrigendum to 'Gender-specific presentations for asthma, allergic rhinitis and eczema in primary care' [Prim Care Resp J 2007;16(1):28-35].

Osman M, Hansell AL, Simpson CR, Hollowell J, Helms PJ.

Prim Care Respir J. 2007 Apr;16(2):126. doi: 10.3132/pcrj.2007.00027. Epub 2007 May 18.


Changing asthma prescribing in primary care 1995-1998.

Simpson CR, Helms PJ, Taylor MW, Adam D G BJ.

Prim Care Respir J. 2001 Jun;10(2):34-36. doi: 10.1038/pcrj.2001.11. Epub 2001 Jun 1.


Seasonal influenza vaccine effectiveness in people with asthma: a national test-negative design case-control study.

Vasileiou E, Sheikh A, Butler CC, Robertson C, Kavanagh K, Englishby T, Lone NI, von Wissmann B, McMenamin J, Ritchie LD, Schwarze J, Gunson R, Simpson CR.

Clin Infect Dis. 2019 Nov 5. pii: ciz1086. doi: 10.1093/cid/ciz1086. [Epub ahead of print]


Performance of Critical Care Outcome Prediction Models in an Intermediate Care Unit.

Brusca RM, Simpson CE, Sahetya SK, Noorain Z, Tanykonda V, Stephens RS, Needham DM, Hager DN.

J Intensive Care Med. 2019 Oct 21:885066619882675. doi: 10.1177/0885066619882675. [Epub ahead of print]


Effect of Direct Oral Anticoagulants, Warfarin, and Antiplatelet Agents on Risk of Device Pocket Hematoma: Combined Analysis of BRUISE CONTROL 1 and 2.

Essebag V, Healey JS, Joza J, Nery PB, Kalfon E, Leiria TLL, Verma A, Ayala-Paredes F, Coutu B, Sumner GL, Becker G, Philippon F, Eikelboom J, Sandhu RK, Sapp J, Leather R, Yung D, Thibault B, Simpson CS, Ahmad K, Toal S, Sturmer M, Kavanagh K, Crystal E, Wells GA, Krahn AD, Birnie DH.

Circ Arrhythm Electrophysiol. 2019 Oct;12(10):e007545. doi: 10.1161/CIRCEP.119.007545. Epub 2019 Oct 15.


Update on long QT syndrome.

Neira V, Enriquez A, Simpson C, Baranchuk A.

J Cardiovasc Electrophysiol. 2019 Oct 9. doi: 10.1111/jce.14227. [Epub ahead of print]


2D Graphene Oxide/Fe-MOF Nanozyme Nest with Superior Peroxidase-Like Activity and Its Application for Detection of Woodsmoke Exposure Biomarker.

Ruan X, Liu D, Niu X, Wang Y, Simpson CD, Cheng N, Du D, Lin Y.

Anal Chem. 2019 Nov 5;91(21):13847-13854. doi: 10.1021/acs.analchem.9b03321. Epub 2019 Oct 17.


Dual-Role Research and Consent by Unique Specialists.

Da Silva M, Zlotnik Shaul R, Simpson C, Boydell K.

Am J Bioeth. 2019 Apr;19(4):46-48. doi: 10.1080/15265161.2019.1572817. No abstract available.


Epilepsy-related and other causes of mortality in people with epilepsy: A systematic review of systematic reviews.

Mbizvo GK, Bennett K, Simpson CR, Duncan SE, Chin RFM.

Epilepsy Res. 2019 Nov;157:106192. doi: 10.1016/j.eplepsyres.2019.106192. Epub 2019 Aug 27. Review.


Predicting the onset of type 2 diabetes using wide and deep learning with electronic health records.

Nguyen BP, Pham HN, Tran H, Nghiem N, Nguyen QH, Do TTT, Tran CT, Simpson CR.

Comput Methods Programs Biomed. 2019 Aug 27;182:105055. doi: 10.1016/j.cmpb.2019.105055. [Epub ahead of print]


Prevalence of the UGT1A1*28 promoter polymorphism and breast cancer risk among African American women in Memphis, TN.

Smith A, Cropp CD, Vidal G, Pritchard E, Cordero J, Simpson C, Starlard-Davenport A.

Cancer Health Disparities. 2019 Aug 19;3:e1-e12. doi: 10.9777/chd.2019.1015.


Healthcare resource utilization and costs among patients with direct oral anticoagulant or warfarin-related major bleeding.

Xu Y, Schulman S, Dowlatshahi D, Holbrook AM, Simpson CS, Shepherd LE, Wells PS, Giulivi A, Gomes T, Mamdani M, Frymire E, Khan S, Johnson AP; Bleeding Effected by Direct Oral Anticoagulants (BLED-AC) Study Group.

Thromb Res. 2019 Oct;182:12-19. doi: 10.1016/j.thromres.2019.07.026. Epub 2019 Aug 2.


LSD1 Inhibition Promotes Epithelial Differentiation through Derepression of Fate-Determining Transcription Factors.

Egolf S, Aubert Y, Doepner M, Anderson A, Maldonado-Lopez A, Pacella G, Lee J, Ko EK, Zou J, Lan Y, Simpson CL, Ridky T, Capell BC.

Cell Rep. 2019 Aug 20;28(8):1981-1992.e7. doi: 10.1016/j.celrep.2019.07.058.


Type 8 long QT syndrome: pathogenic variants in CACNA1C-encoded Cav1.2 cluster in STAC protein binding site.

Mellor GJ, Panwar P, Lee AK, Steinberg C, Hathaway JA, Bartels K, Christian S, Balaji S, Roberts JD, Simpson CS, Boczek NJ, Tester DJ, Radbill AE, Mok NS, Hamilton RM, Kaufman ES, Eugenio PL, Weiss R, January C, McDaniel GM, Leather RA, Erickson C, Falik S, Behr ER, Wilde AAM, Sanatani S, Ackerman MJ, Van Petegem F, Krahn AD, Laksman Z.

Europace. 2019 Nov 1;21(11):1725-1732. doi: 10.1093/europace/euz215.


Deceptive radiographs.

Simpson CD.

Br Dent J. 2019 Aug;227(3):176. doi: 10.1038/s41415-019-0627-6. No abstract available.


Connecting the legs with a spring improves human running economy.

Simpson CS, Welker CG, Uhlrich SD, Sketch SM, Jackson RW, Delp SL, Collins SH, Selinger JC, Hawkes EW.

J Exp Biol. 2019 Sep 3;222(Pt 17). pii: jeb202895. doi: 10.1242/jeb.202895.


HATRIC: a study of Pelargonium sidoides root extract EPs®7630 (Kaloba®) for the treatment of acute cough due to lower respiratory tract infection in adults-study protocol for a double blind, placebo-controlled randomised feasibility trial.

Whitehead A, Simpson C, Willcox M, Webley F, Hay AD, Butler C, Yao L, Wrixon E, Bell M, Bostock J, Little P, Griffiths G, Moore M.

Pilot Feasibility Stud. 2019 Jul 31;5:98. doi: 10.1186/s40814-019-0478-6. eCollection 2019.


Serum uric acid as a marker of disease risk, severity, and survival in systemic sclerosis-related pulmonary arterial hypertension.

Simpson CE, Damico RL, Hummers L, Khair RM, Kolb TM, Hassoun PM, Mathai SC.

Pulm Circ. 2019 Jul 29;9(3):2045894019859477. doi: 10.1177/2045894019859477. eCollection 2019 Jul-Sep.


Deactivation of Implantable Cardioverter Defibrillator in Patients With Terminal Diagnoses.

Trussler A, Alexander B, Campbell D, Alhammad N, Enriquez A, Chacko S, Garrett T, Simpson C, Redfearn D, Abdollah H, Herx L, Baranchuk A.

Am J Cardiol. 2019 Oct 1;124(7):1064-1068. doi: 10.1016/j.amjcard.2019.07.007. Epub 2019 Jul 15.


Global view of the RAF-MEK-ERK module and its immediate downstream effectors.

Santini CC, Longden J, Schoof EM, Simpson CD, Jeschke GR, Creixell P, Kim J, Wu X, Turk BE, Rosen N, Poulikakos PI, Linding R.

Sci Rep. 2019 Jul 26;9(1):10865. doi: 10.1038/s41598-019-47245-x.


Systematic analysis of the intersection of disease mutations with protein modifications.

Simpson CM, Zhang B, Hornbeck PV, Gnad F.

BMC Med Genomics. 2019 Jul 25;12(Suppl 6):109. doi: 10.1186/s12920-019-0543-2.


Predicting asthma attacks in primary care: protocol for developing a machine learning-based prediction model.

Tibble H, Tsanas A, Horne E, Horne R, Mizani M, Simpson CR, Sheikh A.

BMJ Open. 2019 Jul 9;9(7):e028375. doi: 10.1136/bmjopen-2018-028375.


Corrigendum to: The Use of Metabolomics to Identify Biological Signatures of Manganese Exposure.

Baker MG, Simpson CD, Lin YS, Shireman LM, Seixas N.

Ann Work Expo Health. 2019 Jul 1. pii: wxz034. doi: 10.1093/annweh/wxz034. [Epub ahead of print] No abstract available.


Small posterior fossa in Chiari I malformation affected families is significantly linked to 1q43-44 and 12q23-24.11 using whole exome sequencing.

Musolf AM, Ho WSC, Long KA, Zhuang Z, Argersinger DP, Sun H, Moiz BA, Simpson CL, Mendelevich EG, Bogdanov EI, Bailey-Wilson JE, Heiss JD.

Eur J Hum Genet. 2019 Oct;27(10):1599-1610. doi: 10.1038/s41431-019-0457-7. Epub 2019 Jun 21.


Myocardial Fibrosis as a Potential Maladaptive Feature of Right Ventricle Remodeling in Pulmonary Hypertension.

Simpson CE, Hassoun PM.

Am J Respir Crit Care Med. 2019 Sep 15;200(6):662-663. doi: 10.1164/rccm.201906-1154ED. No abstract available.


Contextual analysis of health care at discharge in leprosy: an integrative review.

Pinheiro MGC, Lins SLDF, Gomes BRDS, Simpson CA, Mendes FRP, Miranda FAN.

Rev Gaucha Enferm. 2019 Jun 6;40:e20180258. doi: 10.1590/1983-1447.2019.20180258. Portuguese, English.


Waterlogging Causes Early Modification in the Physiological Performance, Carotenoids, Chlorophylls, Proline, and Soluble Sugars of Cucumber Plants.

Barickman TC, Simpson CR, Sams CE.

Plants (Basel). 2019 Jun 8;8(6). pii: E160. doi: 10.3390/plants8060160.


Ambulatory ECG predictors of atrial fibrillation are ineffective in severe sleep apnea.

Yeung C, Crinion D, Hammond S, Chacko S, Enriquez A, Redfearn D, Simpson C, Abdollah H, Baranchuk A.

J Electrocardiol. 2019 Jul - Aug;55:120-122. doi: 10.1016/j.jelectrocard.2019.05.002. Epub 2019 May 8.


Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs.

van de Kooij B, Creixell P, van Vlimmeren A, Joughin BA, Miller CJ, Haider N, Simpson CD, Linding R, Stambolic V, Turk BE, Yaffe MB.

Elife. 2019 May 24;8. pii: e44635. doi: 10.7554/eLife.44635.


Glossopharyngeal neuralgia: a case report.

Simpson CD, Rahman N, Lamey PJ.

Br J Oral Maxillofac Surg. 2019 Jun;57(5):486-487. doi: 10.1016/j.bjoms.2019.04.005. Epub 2019 May 7. No abstract available.


Concomitant anti-platelet therapy in warfarin-treated patients undergoing cardiac rhythm device implantation: A secondary analysis of the BRUISE CONTROL trial.

Essebag V, AlTurki A, Proietti R, Healey JS, Wells GA, Verma A, Krahn AD, Simpson CS, Ayala-Paredes F, Coutu B, Leather R, Ahmad K, Toal S, Sapp J, Sturmer M, Kavanagh K, Crystal E, Leiria TLL, Seifer C, Rinne C, Birnie D; BRUISE CONTROL Investigators.

Int J Cardiol. 2019 Aug 1;288:87-93. doi: 10.1016/j.ijcard.2019.04.066. Epub 2019 Apr 26.


The UK's pandemic influenza research portfolio: a model for future research on emerging infections.

Simpson CR, Beever D, Challen K, De Angelis D, Fragaszy E, Goodacre S, Hayward A, Lim WS, Rubin GJ, Semple MG, Knight M; NIHR hibernated influenza studies collaborative group.

Lancet Infect Dis. 2019 Aug;19(8):e295-e300. doi: 10.1016/S1473-3099(18)30786-2. Epub 2019 Apr 18. Review.


Comparison of Ajmaline and Procainamide Provocation Tests in the Diagnosis of Brugada Syndrome.

Cheung CC, Mellor G, Deyell MW, Ensam B, Batchvarov V, Papadakis M, Roberts JD, Leather R, Sanatani S, Healey JS, Chauhan VS, Birnie DH, Champagne J, Angaran P, Klein GJ, Yee R, Simpson CS, Talajic M, Gardner M, Yeung-Lai-Wah JA, Chakrabarti S, Laksman ZW, Sharma S, Behr ER, Krahn AD.

JACC Clin Electrophysiol. 2019 Apr;5(4):504-512. doi: 10.1016/j.jacep.2019.01.026. Epub 2019 Mar 27.


Surgical outcomes for chronic exertional compartment syndrome following improved diagnostic criteria.

Simpson C, Roscoe D, Hughes S, Hulse D, Guthrie H.

J R Army Med Corps. 2019 Apr 16. pii: jramc-2019-001171. doi: 10.1136/jramc-2019-001171. [Epub ahead of print]


Urinary mutagenicity and other biomarkers of occupational smoke exposure of wildland firefighters and oxidative stress.

Adetona AM, Martin WK, Warren SH, Hanley NM, Adetona O, Zhang JJ, Simpson C, Paulsen M, Rathbun S, Wang JS, DeMarini DM, Naeher LP.

Inhal Toxicol. 2019 Feb;31(2):73-87. doi: 10.1080/08958378.2019.1600079. Epub 2019 Apr 15.


Integrating eating disorder and weight gain prevention: a pilot and feasibility trial of INSPIRE.

Simpson CC, Burnette CB, Mazzeo SE.

Eat Weight Disord. 2019 Apr 15. doi: 10.1007/s40519-019-00685-w. [Epub ahead of print]


Return to sport following surgical management of triangular fibrocartilage tears: a systematic review.

Robertson G, Ang KK, Maffulli N, Simpson CK, Rust PA.

Br Med Bull. 2019 Jun 19;130(1):89-103. doi: 10.1093/bmb/ldz013.


Office-Based 532-Nanometer Pulsed Potassium-Titanyl-Phosphate Laser Procedures in Laryngology.

Tibbetts KM, Simpson CB.

Otolaryngol Clin North Am. 2019 Jun;52(3):537-557. doi: 10.1016/j.otc.2019.02.011. Epub 2019 Mar 26. Review.


Challenge and Impact of Quinidine Access in Sudden Death Syndromes: A National Experience.

Malhi N, Cheung CC, Deif B, Roberts JD, Gula LJ, Green MS, Pang B, Sultan O, Konieczny KM, Angaran P, Dorian P, Lashevsky I, Healey JS, Alak A, Tadros R, Andorin A, Steinberg C, Ayala-Paredes F, Simpson CS, Atallah J, Krahn AD.

JACC Clin Electrophysiol. 2019 Mar;5(3):376-382. doi: 10.1016/j.jacep.2018.10.007. Epub 2018 Nov 28.


Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output.

Miller CJ, Lou HJ, Simpson C, van de Kooij B, Ha BH, Fisher OS, Pirman NL, Boggon TJ, Rinehart J, Yaffe MB, Linding R, Turk BE.

PLoS Biol. 2019 Mar 21;17(3):e2006540. doi: 10.1371/journal.pbio.2006540. eCollection 2019 Mar.


The Effectiveness of Multitask Learning for Phenotyping with Electronic Health Records Data.

Ding DY, Simpson C, Pfohl S, Kale DC, Jung K, Shah NH.

Pac Symp Biocomput. 2019;24:18-29.


Genome-wide scans of myopia in Pennsylvania Amish families reveal significant linkage to 12q15, 8q21.3 and 5p15.33.

Musolf AM, Simpson CL, Alexander TA, Portas L, Murgia F, Ciner EB, Stambolian D, Bailey-Wilson JE.

Hum Genet. 2019 Apr;138(4):339-354. doi: 10.1007/s00439-019-01991-0. Epub 2019 Mar 2.


Expression of genes controlling steroid metabolism and action in granulosa-lutein cells of women with polycystic ovaries.

Lerner A, Owens LA, Coates M, Simpson C, Poole G, Velupillai J, Liyanage M, Christopoulos G, Lavery S, Hardy K, Franks S.

Mol Cell Endocrinol. 2019 Apr 15;486:47-54. doi: 10.1016/j.mce.2019.02.015. Epub 2019 Feb 22.


Regioselective Hydrogenation of a 60-Carbon Nanographene Molecule toward a Circumbiphenyl Core.

Yao X, Wang XY, Simpson C, Paternò GM, Guizzardi M, Wagner M, Cerullo G, Scotognella F, Watson MD, Narita A, Müllen K.

J Am Chem Soc. 2019 Mar 13;141(10):4230-4234. doi: 10.1021/jacs.9b00384. Epub 2019 Feb 26.


Ventricular mass as a prognostic imaging biomarker in incident pulmonary arterial hypertension.

Simpson CE, Damico RL, Kolb TM, Mathai SC, Khair RM, Sato T, Bourji K, Tedford RJ, Zimmerman SL, Hassoun PM.

Eur Respir J. 2019 Apr 4;53(4). pii: 1802067. doi: 10.1183/13993003.02067-2018. Print 2019 Apr. No abstract available.


Exome genotyping and linkage analysis identifies two novel linked regions and replicates two others for myopia in Ashkenazi Jewish families.

Simpson CL, Musolf AM, Li Q, Portas L, Murgia F, Cordero RY, Cordero JB, Moiz BA, Holzinger ER, Middlebrooks CD, Lewis DD, Bailey-Wilson JE, Stambolian D.

BMC Med Genet. 2019 Jan 31;20(1):27. doi: 10.1186/s12881-019-0752-8.


The Hepatitis C Awareness Through to Treatment (HepCATT) study: improving the cascade of care for hepatitis C virus-infected people who inject drugs in England.

Harrison GI, Murray K, Gore R, Lee P, Sreedharan A, Richardson P, Hughes AJ, Wiselka M, Gelson W, Unitt E, Ratcliff K, Orton A, Trinder K, Simpson C, Ryder SD, Oelbaum S, Foster GR, Christian A, Smith S, Thomson BJ, Reynolds R, Harris M, Hickman M, Irving WL.

Addiction. 2019 Jun;114(6):1113-1122. doi: 10.1111/add.14569. Epub 2019 Mar 12.


Probiotics for preterm infants: A National Retrospective Cohort Study.

Singh B, Shah PS, Afifi J, Simpson CD, Mitra S, Dow K, El-Naggar W; Canadian Neonatal Network Investigators.

J Perinatol. 2019 Apr;39(4):533-539. doi: 10.1038/s41372-019-0315-z. Epub 2019 Jan 28.


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