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Items: 31

1.

Dosimetric impact of uncorrected systematic yaw rotation in VMAT for peripheral lung SABR.

Barrett S, Thirion P, Harper D, Simpkin AJ, Leech M, Hickey K, Ryan L, Marignol L.

Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):520-527. doi: 10.1016/j.rpor.2019.07.010. Epub 2019 Sep 4.

PMID:
31516398
2.

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns.

Kazmi N, Sharp GC, Reese SE, Vehmeijer FO, Lahti J, Page CM, Zhang W, Rifas-Shiman SL, Rezwan FI, Simpkin AJ, Burrows K, Richardson TG, Santos Ferreira DL, Fraser A, Harmon QE, Zhao S, Jaddoe VWV, Czamara D, Binder EB, Magnus MC, Håberg SE, Nystad W, Nohr EA, Starling AP, Kechris KJ, Yang IV, DeMeo DL, Litonjua AA, Baccarelli A, Oken E, Holloway JW, Karmaus W, Arshad SH, Dabelea D, Sørensen TIA, Laivuori H, Raikkonen K, Felix JF, London SJ, Hivert MF, Gaunt TR, Lawlor DA, Relton CL.

Hypertension. 2019 Aug;74(2):375-383. doi: 10.1161/HYPERTENSIONAHA.119.12634. Epub 2019 Jun 24.

PMID:
31230546
3.

A Cluster Randomized-Controlled Trial of the MindOut Social and Emotional Learning Program for Disadvantaged Post-Primary School Students.

Dowling K, Simpkin AJ, Barry MM.

J Youth Adolesc. 2019 Jul;48(7):1245-1263. doi: 10.1007/s10964-019-00987-3. Epub 2019 Apr 19.

PMID:
31004264
4.

Sensitive Periods for the Effect of Childhood Adversity on DNA Methylation: Results From a Prospective, Longitudinal Study.

Dunn EC, Soare TW, Zhu Y, Simpkin AJ, Suderman MJ, Klengel T, Smith ADAC, Ressler KJ, Relton CL.

Biol Psychiatry. 2019 May 15;85(10):838-849. doi: 10.1016/j.biopsych.2018.12.023. Epub 2019 Jan 21. Erratum in: Biol Psychiatry. 2019 Jul 1;86(1):76.

PMID:
30905381
5.

Data on trajectories of measures of cardiovascular health in the Avon Longitudinal Study of Parents and Children (ALSPAC).

O'Keeffe LM, Simpkin AJ, Tilling K, Anderson EL, Hughes AD, Lawlor DA, Fraser A, Howe LD.

Data Brief. 2019 Jan 19;23:103687. doi: 10.1016/j.dib.2019.01.035. eCollection 2019 Apr.

6.

Sex-specific trajectories of measures of cardiovascular health during childhood and adolescence: A prospective cohort study.

O'Keeffe LM, Simpkin AJ, Tilling K, Anderson EL, Hughes AD, Lawlor DA, Fraser A, Howe LD.

Atherosclerosis. 2018 Nov;278:190-196. doi: 10.1016/j.atherosclerosis.2018.09.030. Epub 2018 Sep 27.

PMID:
30296724
7.

Epigenetic gestational age acceleration: a prospective cohort study investigating associations with familial, sociodemographic and birth characteristics.

Khouja JN, Simpkin AJ, O'Keeffe LM, Wade KH, Houtepen LC, Relton CL, Suderman M, Howe LD.

Clin Epigenetics. 2018 Jun 27;10:86. doi: 10.1186/s13148-018-0520-1. eCollection 2018.

8.

SIMBAD: a sequence-independent molecular-replacement pipeline.

Simpkin AJ, Simkovic F, Thomas JMH, Savko M, Lebedev A, Uski V, Ballard C, Wojdyr M, Wu R, Sanishvili R, Xu Y, Lisa MN, Buschiazzo A, Shepard W, Rigden DJ, Keegan RM.

Acta Crystallogr D Struct Biol. 2018 Jul 1;74(Pt 7):595-605. doi: 10.1107/S2059798318005752. Epub 2018 Jun 8.

9.

Low energy availability surrogates correlate with health and performance consequences of Relative Energy Deficiency in Sport.

Ackerman KE, Holtzman B, Cooper KM, Flynn EF, Bruinvels G, Tenforde AS, Popp KL, Simpkin AJ, Parziale AL.

Br J Sports Med. 2019 May;53(10):628-633. doi: 10.1136/bjsports-2017-098958. Epub 2018 Jun 2.

PMID:
29860237
10.

Derivative estimation for longitudinal data analysis: Examining features of blood pressure measured repeatedly during pregnancy.

Simpkin AJ, Durban M, Lawlor DA, MacDonald-Wallis C, May MT, Metcalfe C, Tilling K.

Stat Med. 2018 May 20. doi: 10.1002/sim.7694. [Epub ahead of print]

11.

Recent developments in MrBUMP: better search-model preparation, graphical interaction with search models, and solution improvement and assessment.

Keegan RM, McNicholas SJ, Thomas JMH, Simpkin AJ, Simkovic F, Uski V, Ballard CC, Winn MD, Wilson KS, Rigden DJ.

Acta Crystallogr D Struct Biol. 2018 Mar 1;74(Pt 3):167-182. doi: 10.1107/S2059798318003455. Epub 2018 Mar 6.

12.

Longitudinal analysis strategies for modelling epigenetic trajectories.

Staley JR, Suderman M, Simpkin AJ, Gaunt TR, Heron J, Relton CL, Tilling K.

Int J Epidemiol. 2018 Apr 1;47(2):516-525. doi: 10.1093/ije/dyy012.

13.

Psychosocial adversity and socioeconomic position during childhood and epigenetic age: analysis of two prospective cohort studies.

Lawn RB, Anderson EL, Suderman M, Simpkin AJ, Gaunt TR, Teschendorff AE, Widschwendter M, Hardy R, Kuh D, Relton CL, Howe LD.

Hum Mol Genet. 2018 Apr 1;27(7):1301-1308. doi: 10.1093/hmg/ddy036.

14.

Modelling height in adolescence: a comparison of methods for estimating the age at peak height velocity.

Simpkin AJ, Sayers A, Gilthorpe MS, Heron J, Tilling K.

Ann Hum Biol. 2017 Dec;44(8):715-722. doi: 10.1080/03014460.2017.1391877. Epub 2017 Nov 7.

15.

Are objective measures of physical capability related to accelerated epigenetic age? Findings from a British birth cohort.

Simpkin AJ, Cooper R, Howe LD, Relton CL, Davey Smith G, Teschendorff A, Widschwendter M, Wong A, Kuh D, Hardy R.

BMJ Open. 2017 Nov 1;7(10):e016708. doi: 10.1136/bmjopen-2017-016708.

16.

An epigenome-wide association study meta-analysis of educational attainment.

Karlsson Linnér R, Marioni RE, Rietveld CA, Simpkin AJ, Davies NM, Watanabe K, Armstrong NJ, Auro K, Baumbach C, Bonder MJ, Buchwald J, Fiorito G, Ismail K, Iurato S, Joensuu A, Karell P, Kasela S, Lahti J, McRae AF, Mandaviya PR, Seppälä I, Wang Y, Baglietto L, Binder EB, Harris SE, Hodge AM, Horvath S, Hurme M, Johannesson M, Latvala A, Mather KA, Medland SE, Metspalu A, Milani L, Milne RL, Pattie A, Pedersen NL, Peters A, Polidoro S, Räikkönen K, Severi G, Starr JM, Stolk L, Waldenberger M, Eriksson JG, Esko T, Franke L, Gieger C, Giles GG, Hägg S, Jousilahti P, Kaprio J, Kähönen M, Lehtimäki T, Martin NG, van Meurs JBC, Ollikainen M, Perola M, Posthuma D, Raitakari OT, Sachdev PS, Taskesen E, Uitterlinden AG, Vineis P, Wijmenga C, Wright MJ, Relton C, Davey Smith G, Deary IJ, Koellinger PD, Benjamin DJ.

Mol Psychiatry. 2017 Dec;22(12):1680-1690. doi: 10.1038/mp.2017.210. Epub 2017 Oct 31.

17.

Epigenetic clocks for gestational age: statistical and study design considerations.

Simpkin AJ, Suderman M, Howe LD.

Clin Epigenetics. 2017 Sep 15;9:100. doi: 10.1186/s13148-017-0402-y. eCollection 2017.

18.

Associations of anthropometry since birth with sagittal posture at age 7 in a prospective birth cohort: the Generation XXI Study.

Araújo FA, Lucas R, Simpkin AJ, Heron J, Alegrete N, Tilling K, Howe LD, Barros H.

BMJ Open. 2017 Jul 26;7(7):e013412. doi: 10.1136/bmjopen-2016-013412.

19.

Post-diagnosis serum insulin-like growth factors in relation to dietary and lifestyle changes in the Prostate testing for cancer and Treatment (ProtecT) trial.

Er V, Biernacka K, Simpkin AJ, Martin RM, Jeffreys M, Emmett P, Gilbert R, Avery KNL, Walsh E, Davis M, Donovan JL, Neal DE, Hamdy FC, Holly JMP, Lane JA.

Cancer Causes Control. 2017 Aug;28(8):877-888. doi: 10.1007/s10552-017-0910-2. Epub 2017 Jun 23.

20.

The epigenetic clock and physical development during childhood and adolescence: longitudinal analysis from a UK birth cohort.

Simpkin AJ, Howe LD, Tilling K, Gaunt TR, Lyttleton O, McArdle WL, Ring SM, Horvath S, Smith GD, Relton CL.

Int J Epidemiol. 2017 Apr 1;46(2):549-558. doi: 10.1093/ije/dyw307.

21.

Exploration of a Polygenic Risk Score for Alcohol Consumption: A Longitudinal Analysis from the ALSPAC Cohort.

Taylor M, Simpkin AJ, Haycock PC, Dudbridge F, Zuccolo L.

PLoS One. 2016 Nov 30;11(11):e0167360. doi: 10.1371/journal.pone.0167360. eCollection 2016.

22.

GP0.4 from bacteriophage T7: in silico characterisation of its structure and interaction with E. coli FtsZ.

Simpkin AJ, Rigden DJ.

BMC Res Notes. 2016 Jul 13;9:343. doi: 10.1186/s13104-016-2149-5.

23.

Prostate-specific antigen patterns in US and European populations: comparison of six diverse cohorts.

Simpkin AJ, Donovan JL, Tilling K, Athene Lane J, Martin RM, Albertsen PC, Bill-Axelson A, Ballentine Carter H, Bosch JL, Ferrucci L, Hamdy FC, Holmberg L, Jeffrey Metter E, Neal DE, Parker CC, Metcalfe C.

BJU Int. 2016 Dec;118(6):911-918. doi: 10.1111/bju.13422. Epub 2016 Feb 29.

24.

Assessment of Offspring DNA Methylation across the Lifecourse Associated with Prenatal Maternal Smoking Using Bayesian Mixture Modelling.

de Vocht F, Simpkin AJ, Richmond RC, Relton C, Tilling K.

Int J Environ Res Public Health. 2015 Nov 13;12(11):14461-76. doi: 10.3390/ijerph121114461.

25.

Prenatal and early life influences on epigenetic age in children: a study of mother-offspring pairs from two cohort studies.

Simpkin AJ, Hemani G, Suderman M, Gaunt TR, Lyttleton O, Mcardle WL, Ring SM, Sharp GC, Tilling K, Horvath S, Kunze S, Peters A, Waldenberger M, Ward-Caviness C, Nohr EA, Sørensen TI, Relton CL, Smith GD.

Hum Mol Genet. 2016 Jan 1;25(1):191-201. doi: 10.1093/hmg/ddv456. Epub 2015 Nov 5.

26.

Serine-arginine protein kinase 1 (SRPK1), a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion.

Bullock N, Potts J, Simpkin AJ, Koupparis A, Harper SJ, Oxley J, Oltean S.

J Clin Pathol. 2016 Feb;69(2):171-5. doi: 10.1136/jclinpath-2015-203125. Epub 2015 Oct 23.

27.

Development, validation and evaluation of an instrument for active monitoring of men with clinically localised prostate cancer: systematic review, cohort studies and qualitative study.

Simpkin AJ, Rooshenas L, Wade J, Donovan JL, Lane JA, Martin RM, Metcalfe C, Albertsen PC, Hamdy FC, Holmberg L, Neal DE, Tilling K.

Southampton (UK): NIHR Journals Library; 2015 Jul.

28.

Longitudinal analysis of DNA methylation associated with birth weight and gestational age.

Simpkin AJ, Suderman M, Gaunt TR, Lyttleton O, McArdle WL, Ring SM, Tilling K, Davey Smith G, Relton CL.

Hum Mol Genet. 2015 Jul 1;24(13):3752-63. doi: 10.1093/hmg/ddv119. Epub 2015 Apr 13.

29.

Systematic Review and Meta-analysis of Factors Determining Change to Radical Treatment in Active Surveillance for Localized Prostate Cancer.

Simpkin AJ, Tilling K, Martin RM, Lane JA, Hamdy FC, Holmberg L, Neal DE, Metcalfe C, Donovan JL.

Eur Urol. 2015 Jun;67(6):993-1005. doi: 10.1016/j.eururo.2015.01.004. Epub 2015 Jan 21. Review.

PMID:
25616709
30.

Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC).

Richmond RC, Simpkin AJ, Woodward G, Gaunt TR, Lyttleton O, McArdle WL, Ring SM, Smith AD, Timpson NJ, Tilling K, Davey Smith G, Relton CL.

Hum Mol Genet. 2015 Apr 15;24(8):2201-17. doi: 10.1093/hmg/ddu739. Epub 2014 Dec 30.

31.

Longitudinal prostate-specific antigen reference ranges: Choosing the underlying model of age-related changes.

Simpkin AJ, Metcalfe C, Martin RM, Lane JA, Donovan JL, Hamdy FC, Neal DE, Tilling K.

Stat Methods Med Res. 2016 Oct;25(5):1875-1891. Epub 2013 Oct 9.

PMID:
24108270

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