Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 90

1.

Assessing anxiety symptoms in children: Agreement between parents and children.

Zikopoulou O, Kakaniari K, Simos G.

Psychiatriki. 2019 Jan-Mar;30(1):39-48. doi: 10.22365/jpsych.2019.301.39.

2.

ERK1/2 phosphorylates HIF-2α and regulates its activity by controlling its CRM1-dependent nuclear shuttling.

Gkotinakou IM, Befani C, Simos G, Liakos P.

J Cell Sci. 2019 Apr 8;132(7). pii: jcs225698. doi: 10.1242/jcs.225698.

3.

Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation Under Low Oxygen.

Chachami G, Stankovic-Valentin N, Karagiota A, Basagianni A, Plessmann U, Urlaub H, Melchior F, Simos G.

Mol Cell Proteomics. 2019 Jun;18(6):1197-1209. doi: 10.1074/mcp.RA119.001401. Epub 2019 Mar 29.

PMID:
30926672
4.

Hypoxia-Inducible Factors and the Regulation of Lipid Metabolism.

Mylonis I, Simos G, Paraskeva E.

Cells. 2019 Mar 3;8(3). pii: E214. doi: 10.3390/cells8030214. Review.

5.

Protein phosphatase PPP3CA (calcineurin A) down-regulates hypoxia-inducible factor transcriptional activity.

Karagiota A, Mylonis I, Simos G, Chachami G.

Arch Biochem Biophys. 2019 Mar 30;664:174-182. doi: 10.1016/j.abb.2019.02.007. Epub 2019 Feb 15.

PMID:
30776328
6.

HIF-1α-derived cell-penetrating peptides inhibit ERK-dependent activation of HIF-1 and trigger apoptosis of cancer cells under hypoxia.

Karagiota A, Kourti M, Simos G, Mylonis I.

Cell Mol Life Sci. 2019 Feb;76(4):809-825. doi: 10.1007/s00018-018-2985-7. Epub 2018 Dec 10.

PMID:
30535970
7.

Gagging prevalence and its association with dental fear in 4-12-year-old children in a dental setting.

Katsouda M, Tollili C, Coolidge T, Simos G, Kotsanos N, Arapostathis KN.

Int J Paediatr Dent. 2018 Nov 7. doi: 10.1111/ipd.12445. [Epub ahead of print]

PMID:
30403312
8.

Expression of AGPAT2, an enzyme involved in the glycerophospholipid/triacylglycerol biosynthesis pathway, is directly regulated by HIF-1 and promotes survival and etoposide resistance of cancer cells under hypoxia.

Triantafyllou EA, Georgatsou E, Mylonis I, Simos G, Paraskeva E.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Sep;1863(9):1142-1152. doi: 10.1016/j.bbalip.2018.06.015. Epub 2018 Jun 15.

PMID:
29908837
9.

Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells.

Krishnamoorthy J, Tenkerian C, Gupta J, Ghaddar N, Wang S, Darini C, Staschke KA, Ghosh A, Gandin V, Topisirovic I, Kristof AS, Hatzoglou M, Simos G, Koromilas AE.

Cell Death Dis. 2018 Feb 15;9(3):254. doi: 10.1038/s41419-018-0326-2.

10.

Epidemiology and comorbidity of obsessive-compulsive disorder in late adolescence: a cross-sectional study in senior high schools in Greece.

Politis S, Magklara K, Petrikis P, Michalis G, Simos G, Skapinakis P.

Int J Psychiatry Clin Pract. 2017 Sep;21(3):188-194. doi: 10.1080/13651501.2017.1324038. Epub 2017 May 15.

PMID:
28504027
11.

Mortalin-mediated and ERK-controlled targeting of HIF-1α to mitochondria confers resistance to apoptosis under hypoxia.

Mylonis I, Kourti M, Samiotaki M, Panayotou G, Simos G.

J Cell Sci. 2017 Jan 15;130(2):466-479. doi: 10.1242/jcs.195339. Epub 2016 Dec 1.

12.

HIF-2α phosphorylation by CK1δ promotes erythropoietin secretion in liver cancer cells under hypoxia.

Pangou E, Befani C, Mylonis I, Samiotaki M, Panayotou G, Simos G, Liakos P.

J Cell Sci. 2016 Nov 15;129(22):4213-4226. Epub 2016 Sep 29.

13.

Low Serum Hepcidin in Patients with Autoimmune Liver Diseases.

Lyberopoulou A, Chachami G, Gatselis NK, Kyratzopoulou E, Saitis A, Gabeta S, Eliades P, Paraskeva E, Zachou K, Koukoulis GK, Mamalaki A, Dalekos GN, Simos G.

PLoS One. 2015 Aug 13;10(8):e0135486. doi: 10.1371/journal.pone.0135486. eCollection 2015.

14.

HIF-1α in colorectal carcinoma: review of the literature.

Ioannou M, Paraskeva E, Baxevanidou K, Simos G, Papamichali R, Papacharalambous C, Samara M, Koukoulis G.

J BUON. 2015 May-Jun;20(3):680-9. Review.

15.

CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT complex formation.

Kourti M, Ikonomou G, Giakoumakis NN, Rapsomaniki MA, Landegren U, Siniossoglou S, Lygerou Z, Simos G, Mylonis I.

Cell Signal. 2015 Jun;27(6):1129-40. doi: 10.1016/j.cellsig.2015.02.017. Epub 2015 Mar 3.

16.

A complex signaling network involving protein kinase CK2 is required for hepatitis C virus core protein-mediated modulation of the iron-regulatory hepcidin gene expression.

Foka P, Dimitriadis A, Kyratzopoulou E, Giannimaras DA, Sarno S, Simos G, Georgopoulou U, Mamalaki A.

Cell Mol Life Sci. 2014 Nov;71(21):4243-58. doi: 10.1007/s00018-014-1621-4. Epub 2014 Apr 10.

PMID:
24718935
17.

An association study between hypoxia inducible factor-1alpha (HIF-1α) polymorphisms and osteonecrosis.

Chachami G, Kalousi A, Papatheodorou L, Lyberopoulou A, Nasikas V, Tanimoto K, Simos G, Malizos KN, Georgatsou E.

PLoS One. 2013 Nov 18;8(11):e79647. doi: 10.1371/journal.pone.0079647. eCollection 2013.

18.

Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells.

Befani C, Mylonis I, Gkotinakou IM, Georgoulias P, Hu CJ, Simos G, Liakos P.

Int J Biochem Cell Biol. 2013 Nov;45(11):2359-68. doi: 10.1016/j.biocel.2013.07.025. Epub 2013 Aug 16.

19.

Oxygen-dependent secretion of a bioactive hepcidin-GFP chimera.

Chachami G, Lyberopoulou A, Kalousi A, Paraskeva E, Pantopoulos K, Simos G.

Biochem Biophys Res Commun. 2013 Jun 14;435(4):540-5. doi: 10.1016/j.bbrc.2013.04.085. Epub 2013 May 8.

PMID:
23665013
20.

High serum levels of HIF-1α in psoriatic patients correlate with an over-expression of IL-6.

Vasilopoulos Y, Sourli F, Zafiriou E, Klimi E, Ioannou M, Mamuris Z, Simos G, Koukoulis G, Roussaki-Schulze A.

Cytokine. 2013 Apr;62(1):38-9. doi: 10.1016/j.cyto.2013.02.029. Epub 2013 Mar 19.

PMID:
23517877
21.

MgcRacGAP, a cytoskeleton regulator, inhibits HIF-1 transcriptional activity by blocking its dimerization.

Lyberopoulou A, Mylonis I, Papachristos G, Sagris D, Kalousi A, Befani C, Liakos P, Simos G, Georgatsou E.

Biochim Biophys Acta. 2013 Jun;1833(6):1378-87. doi: 10.1016/j.bbamcr.2013.02.025. Epub 2013 Feb 28.

22.

TNFα induces expression of HIF-1α mRNA and protein but inhibits hypoxic stimulation of HIF-1 transcriptional activity in airway smooth muscle cells.

Tsapournioti S, Mylonis I, Hatziefthimiou A, Ioannou MG, Stamatiou R, Koukoulis GK, Simos G, Molyvdas PA, Paraskeva E.

J Cell Physiol. 2013 Aug;228(8):1745-53. doi: 10.1002/jcp.24331.

PMID:
23359428
23.

Low oxygen tension enhances hepatitis C virus replication.

Vassilaki N, Kalliampakou KI, Kotta-Loizou I, Befani C, Liakos P, Simos G, Mentis AF, Kalliaropoulos A, Doumba PP, Smirlis D, Foka P, Bauhofer O, Poenisch M, Windisch MP, Lee ME, Koskinas J, Bartenschlager R, Mavromara P.

J Virol. 2013 Mar;87(5):2935-48. doi: 10.1128/JVI.02534-12. Epub 2012 Dec 26.

24.

Upregulation of VEGF expression is associated with accumulation of HIF-1α in the skin of naïve scleroderma patients.

Ioannou M, Pyrpasopoulou A, Simos G, Paraskeva E, Nikolaidou C, Venizelos I, Koukoulis G, Aslanidis S, Douma S.

Mod Rheumatol. 2013 Nov;23(6):1245-8. doi: 10.1007/s10165-012-0787-6. Epub 2012 Oct 25.

PMID:
23096096
25.

[A study of the effectiveness of a group-based cognitive-behavioral parent training program].

Konstadinidis L, Goga P, Simos G, Mavreas V.

Psychiatriki. 2012 Jul-Sep;23(3):221-30. Greek, Modern.

PMID:
23073545
26.

Epstein-Barr virus immortalization of human B-cells leads to stabilization of hypoxia-induced factor 1 alpha, congruent with the Warburg effect.

Darekar S, Georgiou K, Yurchenko M, Yenamandra SP, Chachami G, Simos G, Klein G, Kashuba E.

PLoS One. 2012;7(7):e42072. doi: 10.1371/journal.pone.0042072. Epub 2012 Jul 27.

27.

Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression.

Mylonis I, Sembongi H, Befani C, Liakos P, Siniossoglou S, Simos G.

J Cell Sci. 2012 Jul 15;125(Pt 14):3485-93. doi: 10.1242/jcs.106682. Epub 2012 Mar 30.

28.

Collaboration in psychopharmacotherapy.

Simos G.

J Clin Psychol. 2012 Feb;68(2):198-208. doi: 10.1002/jclp.21836.

PMID:
23616300
29.

Bortezomib represses HIF-1α protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells.

Befani CD, Vlachostergios PJ, Hatzidaki E, Patrikidou A, Bonanou S, Simos G, Papandreou CN, Liakos P.

J Mol Med (Berl). 2012 Jan;90(1):45-54. doi: 10.1007/s00109-011-0805-8. Epub 2011 Sep 10. Erratum in: J Mol Med (Berl). 2013 Jun;91(6):771-3.

PMID:
21909688
30.

eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}.

Papadakis AI, Paraskeva E, Peidis P, Muaddi H, Li S, Raptis L, Pantopoulos K, Simos G, Koromilas AE.

Cancer Res. 2010 Oct 15;70(20):7820-9. doi: 10.1158/0008-5472.CAN-10-0215. Epub 2010 Oct 5.

31.

Building arks for tRNA: structure and function of the Arc1p family of non-catalytic tRNA-binding proteins.

Karanasios E, Simos G.

FEBS Lett. 2010 Sep 24;584(18):3842-9. doi: 10.1016/j.febslet.2010.08.023. Epub 2010 Aug 20. Review.

32.

Casein kinase 1 regulates human hypoxia-inducible factor HIF-1.

Kalousi A, Mylonis I, Politou AS, Chachami G, Paraskeva E, Simos G.

J Cell Sci. 2010 Sep 1;123(Pt 17):2976-86. doi: 10.1242/jcs.068122. Epub 2010 Aug 10.

33.

The dietary flavonoid kaempferol effectively inhibits HIF-1 activity and hepatoma cancer cell viability under hypoxic conditions.

Mylonis I, Lakka A, Tsakalof A, Simos G.

Biochem Biophys Res Commun. 2010 Jul 16;398(1):74-8. doi: 10.1016/j.bbrc.2010.06.038. Epub 2010 Jun 15.

PMID:
20558139
34.

Validated analysis of HIF-1alpha expression in cancer cells using a controlled and comparative immunoassay.

Ioannou M, Mylonis I, Kouvaras E, Papamichali R, Daponte A, Paraskeva E, Simos G, Koukoulis GK.

Oncol Rep. 2010 Jul;24(1):161-9.

PMID:
20514457
35.

Isolation of hypoxia-inducible factor 1 (HIF-1) inhibitors from frankincense using a molecularly imprinted polymer.

Lakka A, Mylonis I, Bonanou S, Simos G, Tsakalof A.

Invest New Drugs. 2011 Oct;29(5):1081-9. doi: 10.1007/s10637-010-9440-4. Epub 2010 May 1.

PMID:
20437079
36.

Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7.

Chachami G, Paraskeva E, Mingot JM, Braliou GG, Görlich D, Simos G.

Biochem Biophys Res Commun. 2009 Dec 11;390(2):235-40. doi: 10.1016/j.bbrc.2009.09.093. Epub 2009 Sep 27.

PMID:
19788888
37.

Hypoxia inducible factor-1 alpha and vascular endothelial growth factor in biopsies of small cell lung carcinoma.

Ioannou M, Papamichali R, Kouvaras E, Mylonis I, Vageli D, Kerenidou T, Barbanis S, Daponte A, Simos G, Gourgoulianis K, Koukoulis GK.

Lung. 2009 Sep-Oct;187(5):321-9. doi: 10.1007/s00408-009-9169-z. Epub 2009 Aug 26.

PMID:
19707816
38.

Increased HIF-1 alpha immunostaining in psoriasis compared to psoriasiform dermatitides.

Ioannou M, Sourli F, Mylonis I, Barbanis S, Papamichali R, Kouvaras E, Zafiriou E, Siomou P, Klimi E, Simos G, Roussaki-Schulze AV, Koukoulis G.

J Cutan Pathol. 2009 Dec;36(12):1255-61. doi: 10.1111/j.1600-0560.2009.01264.x. Epub 2009 Jun 26.

PMID:
19563493
39.

Prognostic significance of Hypoxia-Inducible Factor 1 alpha(HIF-1 alpha) expression in serous ovarian cancer: an immunohistochemical study.

Daponte A, Ioannou M, Mylonis I, Simos G, Minas M, Messinis IE, Koukoulis G.

BMC Cancer. 2008 Nov 16;8:335. doi: 10.1186/1471-2407-8-335.

40.

Atypical CRM1-dependent nuclear export signal mediates regulation of hypoxia-inducible factor-1alpha by MAPK.

Mylonis I, Chachami G, Paraskeva E, Simos G.

J Biol Chem. 2008 Oct 10;283(41):27620-7. doi: 10.1074/jbc.M803081200. Epub 2008 Aug 7.

41.

Incorporation of the Arc1p tRNA-binding domain to the catalytic core of MetRS can functionally replace the yeast Arc1p-MetRS complex.

Karanasios E, Boleti H, Simos G.

J Mol Biol. 2008 Sep 5;381(3):763-71. doi: 10.1016/j.jmb.2008.06.044. Epub 2008 Jun 21.

PMID:
18598703
42.

2-Oxoglutarate-dependent oxygenases control hepcidin gene expression.

Braliou GG, Verga Falzacappa MV, Chachami G, Casanovas G, Muckenthaler MU, Simos G.

J Hepatol. 2008 May;48(5):801-10. doi: 10.1016/j.jhep.2007.12.021. Epub 2008 Feb 13.

PMID:
18313788
43.

Flavonoids induce HIF-1alpha but impair its nuclear accumulation and activity.

Triantafyllou A, Mylonis I, Simos G, Bonanou S, Tsakalof A.

Free Radic Biol Med. 2008 Feb 15;44(4):657-70. Epub 2007 Nov 7.

PMID:
18061585
44.

MgcRacGAP interacts with HIF-1alpha and regulates its transcriptional activity.

Lyberopoulou A, Venieris E, Mylonis I, Chachami G, Pappas I, Simos G, Bonanou S, Georgatsou E.

Cell Physiol Biochem. 2007;20(6):995-1006.

45.

Molecular determinants of the yeast Arc1p-aminoacyl-tRNA synthetase complex assembly.

Karanasios E, Simader H, Panayotou G, Suck D, Simos G.

J Mol Biol. 2007 Dec 7;374(4):1077-90. Epub 2007 Oct 11.

PMID:
17976650
46.

Exposure of differentiated airway smooth muscle cells to serum stimulates both induction of hypoxia-inducible factor-1{alpha} and airway responsiveness to ACh.

Chachami G, Hatziefthimiou A, Liakos P, Ioannou MG, Koukoulis GK, Bonanou S, Molyvdas PA, Simos G, Paraskeva E.

Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L913-22. Epub 2007 Jul 27.

47.

The flavonoid quercetin induces hypoxia-inducible factor-1alpha (HIF-1alpha) and inhibits cell proliferation by depleting intracellular iron.

Triantafyllou A, Liakos P, Tsakalof A, Chachami G, Paraskeva E, Molyvdas PA, Georgatsou E, Simos G, Bonanou S.

Free Radic Res. 2007 Mar;41(3):342-56.

PMID:
17364964
48.

Cobalt induces hypoxia-inducible factor-1alpha (HIF-1alpha) in HeLa cells by an iron-independent, but ROS-, PI-3K- and MAPK-dependent mechanism.

Triantafyllou A, Liakos P, Tsakalof A, Georgatsou E, Simos G, Bonanou S.

Free Radic Res. 2006 Aug;40(8):847-56.

PMID:
17015263
49.

Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha.

Mylonis I, Chachami G, Samiotaki M, Panayotou G, Paraskeva E, Kalousi A, Georgatsou E, Bonanou S, Simos G.

J Biol Chem. 2006 Nov 3;281(44):33095-106. Epub 2006 Sep 5.

50.

Structural basis of yeast aminoacyl-tRNA synthetase complex formation revealed by crystal structures of two binary sub-complexes.

Simader H, Hothorn M, Köhler C, Basquin J, Simos G, Suck D.

Nucleic Acids Res. 2006;34(14):3968-79. Epub 2006 Aug 12.

Supplemental Content

Support Center