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Antimicrobial use among adult inpatients at hospital sites within the Canadian Nosocomial Infection Surveillance Program: 2009 to 2016.

Rudnick W, Science M, Thirion DJG, Abdesselam K, Choi KB, Pelude L, Amaratunga K, Comeau JL, Dalton B, Delport J, Dhami R, Embree J, Émond Y, Evans G, Frenette C, Fryters S, German G, Grant JM, Happe J, Katz K, Kibsey P, Kosar J, Langley JM, Lee BE, Lefebvre MA, Leis JA, McGeer A, Neville HL, Simor A, Slayter K, Suh KN, Tse-Chang A, Weiss K, Conly J; Canadian Nosocomial Infection Surveillance Program.

Antimicrob Resist Infect Control. 2020 Feb 13;9(1):32. doi: 10.1186/s13756-020-0684-2.


Sources of viral respiratory infections in Canadian acute care hospital healthcare personnel.

Buckrell S, Coleman BL, McNeil SA, Katz K, Muller MP, Simor A, Loeb M, Powis J, Kuster SP, Di Bella JM, Coleman KK, Drews SJ, Kohler P, McGeer A; Canadian Healthcare Worker Study Group.

J Hosp Infect. 2020 Jan 16. pii: S0195-6701(20)30012-8. doi: 10.1016/j.jhin.2020.01.009. [Epub ahead of print]


The impact of repeated vaccination using 10-year vaccination history on protection against influenza in older adults: a test-negative design study across the 2010/11 to 2015/16 influenza seasons in Ontario, Canada.

Kwong JC, Chung H, Jung JK, Buchan SA, Campigotto A, Campitelli MA, Crowcroft NS, Gubbay JB, Karnauchow T, Katz K, McGeer AJ, McNally JD, Richardson DC, Richardson SE, Rosella LC, Schwartz KL, Simor A, Smieja M, Zahariadis G, On Behalf Of The Canadian Immunization Research Network Cirn Investigators.

Euro Surveill. 2020 Jan;25(1). doi: 10.2807/1560-7917.ES.2020.25.1.1900245.


External validation of clinical prediction rules for complications and mortality following Clostridioides difficile infection.

Beauregard-Paultre C, Abou Chakra CN, McGeer A, Labbé AC, Simor AE, Gold W, Muller MP, Powis J, Katz K, Cadarette SM, Pépin J, Valiquette L.

PLoS One. 2019 Dec 17;14(12):e0226672. doi: 10.1371/journal.pone.0226672. eCollection 2019.


Impact of a comprehensive antimicrobial stewardship program on institutional burden of antimicrobial resistance: a 14-year controlled interrupted time series study.

Peragine C, Walker SAN, Simor A, Walker SE, Kiss A, Leis JA.

Clin Infect Dis. 2019 Dec 9. pii: ciz1183. doi: 10.1093/cid/ciz1183. [Epub ahead of print]


Influenza Vaccine Effectiveness in Preventing Hospitalizations in Older Patients With Chronic Obstructive Pulmonary Disease.

Gershon AS, Chung H, Porter J, Campitelli MA, Buchan SA, Schwartz KL, Crowcroft NS, Campigotto A, Gubbay JB, Karnauchow T, Katz K, McGeer AJ, McNally JD, Richardson DC, Richardson SE, Rosella LC, Simor AE, Smieja M, Zahariadis G, Kwong JC.

J Infect Dis. 2020 Jan 1;221(1):42-52. doi: 10.1093/infdis/jiz419.


Trends in health care-associated infections in acute care hospitals in Canada: an analysis of repeated point-prevalence surveys.

Mitchell R, Taylor G, Rudnick W, Alexandre S, Bush K, Forrester L, Frenette C, Granfield B, Gravel-Tropper D, Happe J, John M, Lavallee C, McGeer A, Mertz D, Pelude L, Science M, Simor A, Smith S, Suh KN, Vayalumkal J, Wong A, Amaratunga K; Canadian Nosocomial Infection Surveillance Program.

CMAJ. 2019 Sep 9;191(36):E981-E988. doi: 10.1503/cmaj.190361.


Influenza Vaccine Effectiveness Among Patients With Cancer: A Population-Based Study Using Health Administrative and Laboratory Testing Data From Ontario, Canada.

Blanchette PS, Chung H, Pritchard KI, Earle CC, Campitelli MA, Buchan SA, Schwartz KL, Crowcroft NS, Gubbay JB, Karnauchow T, Katz K, McGeer AJ, McNally JD, Richardson DC, Richardson SE, Rosella LC, Simor A, Smieja M, Zahariadis G, Campigotto A, Kwong JC.

J Clin Oncol. 2019 Oct 20;37(30):2795-2804. doi: 10.1200/JCO.19.00354. Epub 2019 Aug 29.


Can routinely collected laboratory and health administrative data be used to assess influenza vaccine effectiveness? Assessing the validity of the Flu and Other Respiratory Viruses Research (FOREVER) Cohort.

Kwong JC, Buchan SA, Chung H, Campitelli MA, Schwartz KL, Crowcroft NS, Jackson ML, Karnauchow T, Katz K, McGeer AJ, McNally JD, Richardson DC, Richardson SE, Rosella LC, Simor A, Smieja M, Zahariadis G, Campigotto A, Gubbay JB.

Vaccine. 2019 Jul 18;37(31):4392-4400. doi: 10.1016/j.vaccine.2019.06.011. Epub 2019 Jun 17.


Which healthcare workers work with acute respiratory illness? Evidence from Canadian acute-care hospitals during 4 influenza seasons: 2010-2011 to 2013-2014.

Jiang L, McGeer A, McNeil S, Katz K, Loeb M, Muller MP, Simor A, Powis J, Kohler P, Di Bella JM, Coleman BL; Canadian Healthcare Worker Study Group.

Infect Control Hosp Epidemiol. 2019 Aug;40(8):889-896. doi: 10.1017/ice.2019.141. Epub 2019 Jun 18.


Association of Increased Colony-Count Threshold for Urinary Pathogens in Hospitalized Patients With Antimicrobial Treatment.

Smith MA, Puckrin R, Lam PW, Lamb MJ, Simor AE, Leis JA.

JAMA Intern Med. 2019 Jul 1;179(7):990-992. doi: 10.1001/jamainternmed.2019.0188. No abstract available.


Characteristics and Outcomes of Young Children Hospitalized With Laboratory-confirmed Influenza or Respiratory Syncytial Virus in Ontario, Canada, 2009-2014.

Buchan SA, Chung H, Karnauchow T, McNally JD, Campitelli MA, Gubbay JB, Katz K, McGeer AJ, Richardson DC, Richardson SE, Simor A, Smieja M, Zahariadis G, Tran D, Crowcroft NS, Rosella LC, Kwong JC.

Pediatr Infect Dis J. 2019 Apr;38(4):362-369. doi: 10.1097/INF.0000000000002164.


Multilocus Variable-Number Tandem-Repeat Analysis of Clostridioides difficile Clusters in Ribotype 027 Isolates and Lack of Association with Clinical Outcomes.

Garneau JR, Abou Chakra CN, Fortier LC, Labbé AC, Simor AE, Gold W, Muller M, McGeer A, Powis J, Katz K, Pépin J, Valiquette L.

J Clin Microbiol. 2019 Apr 26;57(5). pii: e01724-18. doi: 10.1128/JCM.01724-18. Print 2019 May.


Prevalence of antibiotic-resistant organisms in Canadian Hospitals. Comparison of point-prevalence survey results from 2010, 2012, and 2016.

Martin P, Abou Chakra CN, Williams V, Bush K, Dyck M, Hirji Z, Kiss A, Larios OE, McGeer A, Moore C, Weiss K, Simor AE; Infection Prevention and Control Canada.

Infect Control Hosp Epidemiol. 2019 Jan;40(1):53-59. doi: 10.1017/ice.2018.279. Epub 2018 Nov 5.


Results from the Canadian Nosocomial Infection Surveillance Program for detection of carbapenemase-producing Acinetobacter spp. in Canadian hospitals, 2010-16.

Boyd DA, Mataseje LF, Pelude L, Mitchell R, Bryce E, Roscoe D, Embree J, Katz K, Kibsey P, Lavallee C, Simor AE, Taylor G, Turgeon N, Langley JM, Amaratunga K, Mulvey MR; Canadian Nosocomial Infection Surveillance Program.

J Antimicrob Chemother. 2019 Feb 1;74(2):315-320. doi: 10.1093/jac/dky416.


Rapid Identification of Candida Species from Positive Blood Cultures by Use of the FilmArray Blood Culture Identification Panel.

Simor AE, Porter V, Mubareka S, Chouinard M, Katz K, Vermeiren C, Fattouh R, Matukas LM, Tadros M, Mazzulli T, Poutanen S.

J Clin Microbiol. 2018 Nov 27;56(12). pii: e01387-18. doi: 10.1128/JCM.01387-18. Print 2018 Dec. No abstract available.


Comparison of qPCR versus culture for the detection and quantification of Clostridium difficile environmental contamination.

MacDougall LK, Broukhanski G, Simor A, Johnstone J, Mubareka S, McGeer A, Daneman N, Garber G, Brown KA.

PLoS One. 2018 Aug 30;13(8):e0201569. doi: 10.1371/journal.pone.0201569. eCollection 2018.


Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia.

Than NG, Romero R, Tarca AL, Kekesi KA, Xu Y, Xu Z, Juhasz K, Bhatti G, Leavitt RJ, Gelencser Z, Palhalmi J, Chung TH, Gyorffy BA, Orosz L, Demeter A, Szecsi A, Hunyadi-Gulyas E, Darula Z, Simor A, Eder K, Szabo S, Topping V, El-Azzamy H, LaJeunesse C, Balogh A, Szalai G, Land S, Torok O, Dong Z, Kovalszky I, Falus A, Meiri H, Draghici S, Hassan SS, Chaiworapongsa T, Krispin M, Knöfler M, Erez O, Burton GJ, Kim CJ, Juhasz G, Papp Z.

Front Immunol. 2018 Aug 8;9:1661. doi: 10.3389/fimmu.2018.01661. eCollection 2018.


Emergence of Carbapenemase-Producing Enterobacteriaceae, South-Central Ontario, Canada1.

Kohler PP, Melano RG, Patel SN, Shafinaz S, Faheem A, Coleman BL, Green K, Armstrong I, Almohri H, Borgia S, Borgundvaag E, Johnstone J, Katz K, Lam F, Muller MP, Powis J, Poutanen SM, Richardson D, Rebbapragada A, Sarabia A, Simor A, McGeer A; Toronto Invasive Bacterial Diseases Network (TIBDN).

Emerg Infect Dis. 2018 Sep;24(9):1674-1682. doi: 10.3201/eid2409.180164.


Nosocomial outbreak of vanD-carrying vancomycin-resistant Enterococcus faecium.

Lam PW, Kozak RA, Eshaghi A, Avaness M, Salt N, Patel SN, Simor AE, Leis JA.

Infect Control Hosp Epidemiol. 2018 Oct;39(10):1266-1268. doi: 10.1017/ice.2018.174. Epub 2018 Aug 16. No abstract available.


Increased environmental sample area and recovery of Clostridium difficile spores from hospital surfaces by quantitative PCR and enrichment culture.

Brown KA, MacDougall LK, Valenta K, Simor A, Johnstone J, Mubareka S, Broukhanski G, Garber G, McGeer A, Daneman N.

Infect Control Hosp Epidemiol. 2018 Aug;39(8):917-923. doi: 10.1017/ice.2018.103.


The evolving epidemiology of Clostridium difficile infection in Canadian hospitals during a postepidemic period (2009-2015).

Katz KC, Golding GR, Choi KB, Pelude L, Amaratunga KR, Taljaard M, Alexandre S, Collet JC, Davis I, Du T, Evans GA, Frenette C, Gravel D, Hota S, Kibsey P, Langley JM, Lee BE, Lemieux C, Longtin Y, Mertz D, Mieusement LMD, Minion J, Moore DL, Mulvey MR, Richardson S, Science M, Simor AE, Stagg P, Suh KN, Taylor G, Wong A, Thampi N; Canadian Nosocomial Infection Surveillance Program.

CMAJ. 2018 Jun 25;190(25):E758-E765. doi: 10.1503/cmaj.180013.


Nasal colonization with Streptococcus pneumoniae and Staphylococcus aureus among hospitalized patients with laboratory-confirmed influenza.

Campigotto A, Simor AE, McGeer A, Kiss A, Mubareka S.

Diagn Microbiol Infect Dis. 2018 Oct;92(2):133-135. doi: 10.1016/j.diagmicrobio.2018.05.007. Epub 2018 Jun 5.


Immunogenicity and reactogenicity of high- vs. standard-dose trivalent inactivated influenza vaccine in healthcare workers: a pilot randomized controlled trial.

Volling C, Coleman BL, Katz K, Simor AE, Muller M, Powis J, McElhaney J, McGeer A.

Clin Microbiol Infect. 2019 Feb;25(2):217-224. doi: 10.1016/j.cmi.2018.05.002. Epub 2018 May 18.


Automatic notification and infectious diseases consultation for patients with Staphylococcus aureus bacteremia.

Djelic L, Andany N, Craig J, Daneman N, Simor A, Leis JA.

Diagn Microbiol Infect Dis. 2018 Jul;91(3):282-283. doi: 10.1016/j.diagmicrobio.2018.03.001. Epub 2018 Mar 3.


Factors associated with influenza vaccination among healthcare workers in acute care hospitals in Canada.

Hussain H, McGeer A, McNeil S, Katz K, Loeb M, Simor A, Powis J, Langley J, Muller M; Canadian Health Care Worker Study Group, Coleman BL.

Influenza Other Respir Viruses. 2018 May;12(3):319-325. doi: 10.1111/irv.12545. Epub 2018 Mar 2.


Clinical Significance of Low Colony-Count Urine Cultures Among Hospitalized Inpatients.

Smith MA, Lamb MJ, Baillie L, Simor A, Leis JA.

Infect Control Hosp Epidemiol. 2018 Apr;39(4):488-489. doi: 10.1017/ice.2017.324. Epub 2018 Feb 12. No abstract available.


Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection.

Kwong JC, Schwartz KL, Campitelli MA, Chung H, Crowcroft NS, Karnauchow T, Katz K, Ko DT, McGeer AJ, McNally D, Richardson DC, Rosella LC, Simor A, Smieja M, Zahariadis G, Gubbay JB.

N Engl J Med. 2018 Jan 25;378(4):345-353. doi: 10.1056/NEJMoa1702090.


Steady-State Pharmacokinetics of Oral Ciprofloxacin in Continuous Cycling Peritoneal Dialysis Patients: Brief Report.

Lee C, Walker SAN, Palmay L, Walker SE, Tobe S, Simor A.

Perit Dial Int. 2018 Jan-Feb;38(1):73-76. doi: 10.3747/pdi.2017.00052.


Vaccine effectiveness against laboratory-confirmed influenza hospitalizations among young children during the 2010-11 to 2013-14 influenza seasons in Ontario, Canada.

Buchan SA, Chung H, Campitelli MA, Crowcroft NS, Gubbay JB, Karnauchow T, Katz K, McGeer AJ, McNally JD, Richardson D, Richardson SE, Rosella LC, Simor A, Smieja M, Tran D, Zahariadis G, Kwong JC.

PLoS One. 2017 Nov 17;12(11):e0187834. doi: 10.1371/journal.pone.0187834. eCollection 2017.


Evaluation of the β-Lacta Test for Detection of Extended-Spectrum-β-Lactamase (ESBL)-Producing Organisms Directly from Positive Blood Cultures by Use of Smudge Plates.

Hasso M, Porter V, Simor AE.

J Clin Microbiol. 2017 Dec;55(12):3560-3562. doi: 10.1128/JCM.01354-17. Epub 2017 Oct 11. No abstract available.


Susceptibilities of clinical Clostridium difficile isolates to antimicrobials: a systematic review and meta-analysis of studies since 1970.

Khanafer N, Daneman N, Greene T, Simor A, Vanhems P, Samore M, Brown KA.

Clin Microbiol Infect. 2018 Feb;24(2):110-117. doi: 10.1016/j.cmi.2017.07.012. Epub 2017 Jul 24. Review.


A prospective study evaluating tobramycin pharmacokinetics and optimal once daily dosing in burn patients.

Lee C, Walker SAN, Walker SE, Seto W, Simor A, Jeschke M.

Burns. 2017 Dec;43(8):1766-1774. doi: 10.1016/j.burns.2017.05.009. Epub 2017 Jun 21.


Pre-and post-pandemic trends in antiviral use in hospitalized patients with laboratory-confirmed influenza: 2004/05-2013/14, Toronto, Canada.

Coleman BL, Hassan K, Green K, Gubbay JB, Katz K, Mazzulli T, McNeil S, Muller M, Powis J, Richardson D, Simor A; TIBDN, McGeer AJ.

Antiviral Res. 2017 Apr;140:158-163. doi: 10.1016/j.antiviral.2017.01.025. Epub 2017 Feb 6.


The short- and long-term proteomic effects of sleep deprivation on the cortical and thalamic synapses.

Simor A, Györffy BA, Gulyássy P, Völgyi K, Tóth V, Todorov MI, Kis V, Borhegyi Z, Szabó Z, Janáky T, Drahos L, Juhász G, Kékesi KA.

Mol Cell Neurosci. 2017 Mar;79:64-80. doi: 10.1016/j.mcn.2017.01.002. Epub 2017 Jan 10.


A 14-Year Audit and Analysis of Human Skin Allograft Discards.

Spradbrow J, Etchells M, Cartotto R, Halliday A, Lin Y, Simor A, Visvalingam R, Callum J.

J Burn Care Res. 2017 Sep/Oct;38(5):e786-e795. doi: 10.1097/BCR.0000000000000485.


Elimination of Screening Urine Cultures Prior to Elective Joint Arthroplasty.

Lamb MJ, Baillie L, Pajak D, Flynn J, Bansal V, Simor A, Vearncombe M, Walker SA, Clark S, Gollish J, Leis JA.

Clin Infect Dis. 2017 Mar 15;64(6):806-809. doi: 10.1093/cid/ciw848.


Community- and Healthcare-Associated Methicillin-Resistant Staphylococcus aureus Strains: An Investigation Into Household Transmission, Risk Factors, and Environmental Contamination.

Ng W, Faheem A, McGeer A, Simor AE, Gelosia A, Willey BM, Watt C, Richardson DC, Wong H, Ostrowska K, Vernich L, Muller MP, Gnanasuntharam P, Porter V, Katz K.

Infect Control Hosp Epidemiol. 2017 Jan;38(1):61-67. doi: 10.1017/ice.2016.245. Epub 2016 Nov 8.


Acquisition of methicillin-resistant Staphylococcus aureus (MRSA) in contacts of patients newly identified as colonized or infected with MRSA in the immediate postexposure and postdischarge periods.

Williams VR, Callery S, Vearncombe M, Simor AE.

Am J Infect Control. 2017 Mar 1;45(3):295-297. doi: 10.1016/j.ajic.2016.09.009. Epub 2016 Oct 17.


Results from the Canadian Nosocomial Infection Surveillance Program on Carbapenemase-Producing Enterobacteriaceae, 2010 to 2014.

Mataseje LF, Abdesselam K, Vachon J, Mitchel R, Bryce E, Roscoe D, Boyd DA, Embree J, Katz K, Kibsey P, Simor AE, Taylor G, Turgeon N, Langley J, Gravel D, Amaratunga K, Mulvey MR.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6787-6794. doi: 10.1128/AAC.01359-16. Print 2016 Nov.


Patient Characteristics and Outcomes of Outpatient Parenteral Antimicrobial Therapy: A Retrospective Study.

Yan M, Elligsen M, Simor AE, Daneman N.

Can J Infect Dis Med Microbiol. 2016;2016:8435257. doi: 10.1155/2016/8435257. Epub 2016 Feb 22.


Incidence and Risk Factors for Infection Following Transcatheter Aortic Valve Implantation.

Shi Y, Wijeysundera HC, Fremes SE, Simor AE.

Infect Control Hosp Epidemiol. 2016 Sep;37(9):1094-7. doi: 10.1017/ice.2016.128. Epub 2016 Jun 20.


Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation.

Völgyi K, Háden K, Kis V, Gulyássy P, Badics K, Györffy BA, Simor A, Szabó Z, Janáky T, Drahos L, Dobolyi Á, Penke B, Juhász G, Kékesi KA.

Mol Neurobiol. 2017 Apr;54(3):2060-2078. doi: 10.1007/s12035-015-9682-4. Epub 2016 Feb 24.


Determinants of Outcome in Hospitalized Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infection: Results From National Surveillance in Canada, 2008-2012.

Simor AE, Pelude L, Golding G, Fernandes R, Bryce E, Frenette C, Gravel D, Katz K, McGeer A, Mulvey MR, Smith S, Weiss K; Canadian Nosocomial Infection Surveillance Program.

Infect Control Hosp Epidemiol. 2016 Apr;37(4):390-7. doi: 10.1017/ice.2015.323. Epub 2016 Jan 19.


Antibiotic Use and Need for Antimicrobial Stewardship in Long-Term Care.

Wu LD, Walker SA, Elligsen M, Palmay L, Simor A, Daneman N.

Can J Hosp Pharm. 2015 Nov-Dec;68(6):445-9. Erratum in: Can J Hosp Pharm. 2017 May-Jun;70(3):224.


Impact of infection with extended-spectrum β-lactamase-producing Escherichia coli or Klebsiella species on outcome and hospitalization costs.

Maslikowska JA, Walker SA, Elligsen M, Mittmann N, Palmay L, Daneman N, Simor A.

J Hosp Infect. 2016 Jan;92(1):33-41. doi: 10.1016/j.jhin.2015.10.001. Epub 2015 Oct 22.


Impact of hospital length of stay on the distribution of Gram negative bacteria and likelihood of isolating a resistant organism in a Canadian burn center.

Wanis M, Walker SAN, Daneman N, Elligsen M, Palmay L, Simor A, Cartotto R.

Burns. 2016 Feb;42(1):104-111. doi: 10.1016/j.burns.2015.07.010. Epub 2015 Nov 5.


Bacteremia caused by a mecA-positive oxacillin-susceptible Staphylococcus aureus strain with inducible resistance.

Kong LY, Jean A, Wong H, Semret M, Frenette C, Simor AE, Fenn S, Loo VG.

Diagn Microbiol Infect Dis. 2015 Dec;83(4):377-8. doi: 10.1016/j.diagmicrobio.2015.09.001. Epub 2015 Sep 4. No abstract available.


Factors Associated With Complications of Clostridium difficile Infection in a Multicenter Prospective Cohort.

Abou Chakra CN, McGeer A, Labbé AC, Simor AE, Gold WL, Muller MP, Powis J, Katz K, Garneau JR, Fortier LC, Pépin J, Cadarette SM, Valiquette L.

Clin Infect Dis. 2015 Dec 15;61(12):1781-8. doi: 10.1093/cid/civ749. Epub 2015 Sep 3.

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