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Items: 1 to 50 of 55

1.

Telomere length and physical performance among older people-The Helsinki Birth Cohort Study.

Åström MJ, von Bonsdorff MB, Perälä MM, Salonen MK, Rantanen T, Kajantie E, Simonen M, Pohjolainen P, Haapanen MJ, Guzzardi MA, Iozzo P, Kautiainen H, Eriksson JG.

Mech Ageing Dev. 2019 Oct;183:111145. doi: 10.1016/j.mad.2019.111145. Epub 2019 Sep 3.

PMID:
31491428
2.

Association between dog ownership and type 2 diabetes in later life: the Helsinki birth cohort study.

Laine MK, Wasenius NS, Lohi H, Simonen M, Tiira K, Eriksson JG, Salonen MK.

Int J Circumpolar Health. 2019 Dec;78(1):1611328. doi: 10.1080/22423982.2019.1611328.

3.

The Healthy Nordic Diet and Mediterranean Diet and Incidence of Disability 10 Years Later in Home-Dwelling Old Adults.

Perälä MM, von Bonsdorff MB, Männistö S, Salonen MK, Simonen M, Pohjolainen P, Kajantie E, Rantanen T, Eriksson JG.

J Am Med Dir Assoc. 2019 May;20(5):511-516.e1. doi: 10.1016/j.jamda.2018.09.001. Epub 2018 Oct 23.

PMID:
30366763
4.

Dog Ownership from a Life Course Perspective and Leisure-time Physical Activity in Late Adulthood: The Helsinki Birth Cohort Study.

Wasenius NS, Laine MK, Savola S, Simonen M, Tiira K, Lohi H, Eriksson JG, Salonen MK.

Am J Health Behav. 2018 Nov 1;42(6):11-18. doi: 10.5993/AJHB.42.6.2.

PMID:
30157997
5.

Early life stress and frailty in old age: the Helsinki birth cohort study.

Haapanen MJ, Perälä MM, Salonen MK, Kajantie E, Simonen M, Pohjolainen P, Pesonen AK, Räikkönen K, Eriksson JG, von Bonsdorff MB.

BMC Geriatr. 2018 Aug 13;18(1):179. doi: 10.1186/s12877-018-0873-5.

6.

Effect of maternal weight during pregnancy on offspring muscle strength response to resistance training in late adulthood.

Wasenius NS, Simonen M, Penttinen L, Salonen MK, Sandboge S, Eriksson JG.

Adv Med Sci. 2018 Sep;63(2):353-358. doi: 10.1016/j.advms.2018.07.001. Epub 2018 Aug 10.

PMID:
30099329
7.

Telomere Length and Frailty: The Helsinki Birth Cohort Study.

Haapanen MJ, Perälä MM, Salonen MK, Guzzardi MA, Iozzo P, Kajantie E, Rantanen T, Simonen M, Pohjolainen P, Eriksson JG, von Bonsdorff MB.

J Am Med Dir Assoc. 2018 Aug;19(8):658-662. doi: 10.1016/j.jamda.2018.05.011. Epub 2018 Jun 28.

8.

Infant and childhood growth and frailty in old age: the Helsinki Birth Cohort Study.

Haapanen MJ, Perälä MM, Osmond C, Salonen MK, Kajantie E, Rantanen T, Simonen M, Pohjolainen P, Eriksson JG, von Bonsdorff MB.

Aging Clin Exp Res. 2019 May;31(5):717-721. doi: 10.1007/s40520-018-1011-0. Epub 2018 Jul 24.

PMID:
30043315
9.

Glucose regulation and physical performance among older people: the Helsinki Birth Cohort Study.

Åström MJ, von Bonsdorff MB, Perälä MM, Salonen MK, Rantanen T, Kajantie E, Simonen M, Pohjolainen P, Osmond C, Eriksson JG.

Acta Diabetol. 2018 Oct;55(10):1051-1058. doi: 10.1007/s00592-018-1192-1. Epub 2018 Jul 21.

10.

Body composition as a predictor of physical performance in older age: A ten-year follow-up of the Helsinki Birth Cohort Study.

Mikkola TM, von Bonsdorff MB, Salonen MK, Simonen M, Pohjolainen P, Osmond C, Perälä MM, Rantanen T, Kajantie E, Eriksson JG.

Arch Gerontol Geriatr. 2018 Jul - Aug;77:163-168. doi: 10.1016/j.archger.2018.05.009. Epub 2018 May 14.

11.

Early life determinants of frailty in old age: the Helsinki Birth Cohort Study.

Haapanen MJ, Perälä MM, Salonen MK, Kajantie E, Simonen M, Pohjolainen P, Eriksson JG, von Bonsdorff MB.

Age Ageing. 2018 Jul 1;47(4):569-575. doi: 10.1093/ageing/afy052.

PMID:
29659671
12.

Relationship between physical activity and physical performance in later life in different birth weight groups.

Jantunen H, Wasenius NS, Salonen MK, Perälä MM, Kautiainen H, Simonen M, Pohjolainen P, Kajantie E, von Bonsdorff MB, Eriksson JG.

J Dev Orig Health Dis. 2018 Feb;9(1):95-101. doi: 10.1017/S2040174417000575. Epub 2017 Aug 7.

PMID:
28780911
13.

The healthy Nordic diet predicts muscle strength 10 years later in old women, but not old men.

Perälä MM, von Bonsdorff MB, Männistö S, Salonen MK, Simonen M, Kanerva N, Rantanen T, Pohjolainen P, Eriksson JG.

Age Ageing. 2017 Jul 1;46(4):588-594. doi: 10.1093/ageing/afx034.

PMID:
28338859
14.

Objectively measured physical activity and physical performance in old age.

Jantunen H, Wasenius N, Salonen MK, Perälä MM, Osmond C, Kautiainen H, Simonen M, Pohjolainen P, Kajantie E, Rantanen T, von Bonsdorff MB, Eriksson JG.

Age Ageing. 2017 Mar 1;46(2):232-237. doi: 10.1093/ageing/afw194.

15.

A healthy Nordic diet and physical performance in old age: findings from the longitudinal Helsinki Birth Cohort Study.

Perälä MM, von Bonsdorff M, Männistö S, Salonen MK, Simonen M, Kanerva N, Pohjolainen P, Kajantie E, Rantanen T, Eriksson JG.

Br J Nutr. 2016 Mar 14;115(5):878-86. doi: 10.1017/S0007114515005309. Epub 2016 Jan 20.

PMID:
26785760
16.

Prenatal and childhood growth and physical performance in old age--findings from the Helsinki Birth Cohort Study 1934-1944.

Eriksson JG, Osmond C, Perälä MM, Salonen MK, Simonen M, Pohjolainen P, Kajantie E, Rantanen T, von Bonsdorff MB.

Age (Dordr). 2015 Dec;37(6):108. doi: 10.1007/s11357-015-9846-1. Epub 2015 Oct 24.

17.

Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans.

Männistö VT, Simonen M, Hyysalo J, Soininen P, Kangas AJ, Kaminska D, Matte AK, Venesmaa S, Käkelä P, Kärjä V, Arola J, Gylling H, Cederberg H, Kuusisto J, Laakso M, Yki-Järvinen H, Ala-Korpela M, Pihlajamäki J.

Liver Int. 2015 Jul;35(7):1853-61. doi: 10.1111/liv.12769. Epub 2015 Jan 20.

PMID:
25533197
18.

Lipoprotein subclass metabolism in nonalcoholic steatohepatitis.

Männistö VT, Simonen M, Soininen P, Tiainen M, Kangas AJ, Kaminska D, Venesmaa S, Käkelä P, Kärjä V, Gylling H, Ala-Korpela M, Pihlajamäki J.

J Lipid Res. 2014 Dec;55(12):2676-84. doi: 10.1194/jlr.P054387. Epub 2014 Oct 24. Erratum in: J Lipid Res. 2016 Apr;57(4):743.

19.

A population-based study on the prevalence of NASH using scores validated against liver histology.

Hyysalo J, Männistö VT, Zhou Y, Arola J, Kärjä V, Leivonen M, Juuti A, Jaser N, Lallukka S, Käkelä P, Venesmaa S, Simonen M, Saltevo J, Moilanen L, Korpi-Hyövalti E, Keinänen-Kiukaanniemi S, Oksa H, Orho-Melander M, Valenti L, Fargion S, Pihlajamäki J, Peltonen M, Yki-Järvinen H.

J Hepatol. 2014 Apr;60(4):839-46. doi: 10.1016/j.jhep.2013.12.009. Epub 2013 Dec 12.

PMID:
24333862
20.

Desmosterol in human nonalcoholic steatohepatitis.

Simonen M, Männistö V, Leppänen J, Kaminska D, Kärjä V, Venesmaa S, Käkelä P, Kuusisto J, Gylling H, Laakso M, Pihlajamäki J.

Hepatology. 2013 Sep;58(3):976-82. doi: 10.1002/hep.26342. Epub 2013 Jul 29.

PMID:
23447451
21.

Conjugated bile acids associate with altered rates of glucose and lipid oxidation after Roux-en-Y gastric bypass.

Simonen M, Dali-Youcef N, Kaminska D, Venesmaa S, Käkelä P, Pääkkönen M, Hallikainen M, Kolehmainen M, Uusitupa M, Moilanen L, Laakso M, Gylling H, Patti ME, Auwerx J, Pihlajamäki J.

Obes Surg. 2012 Sep;22(9):1473-80. doi: 10.1007/s11695-012-0673-5.

22.

Formulation in clinical interviews.

Simonen M.

Commun Med. 2012;9(2):133-43.

PMID:
24498698
23.

Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans.

Pihlajamäki J, Kuulasmaa T, Kaminska D, Simonen M, Kärjä V, Grönlund S, Käkelä P, Pääkkönen M, Kainulainen S, Punnonen K, Kuusisto J, Gylling H, Laakso M.

J Hepatol. 2012 Mar;56(3):663-70. doi: 10.1016/j.jhep.2011.10.005. Epub 2011 Oct 23.

PMID:
22027586
24.

A large Finnish echovirus 30 outbreak was preceded by silent circulation of the same genotype.

Savolainen-Kopra C, Paananen A, Blomqvist S, Klemola P, Simonen ML, Lappalainen M, Vuorinen T, Kuusi M, Lemey P, Roivainen M.

Virus Genes. 2011 Feb;42(1):28-36. doi: 10.1007/s11262-010-0536-x. Epub 2010 Oct 20.

PMID:
20960045
25.

Research utilisation among nursing teachers in Finland: a national survey.

Koivula M, Tarkka MT, Simonen M, Katajisto J, Salminen L.

Nurse Educ Today. 2011 Jan;31(1):24-30. doi: 10.1016/j.nedt.2010.03.008. Epub 2010 Jun 1.

PMID:
20605663
26.

Co-circulation of coxsackieviruses A6 and A10 in hand, foot and mouth disease outbreak in Finland.

Blomqvist S, Klemola P, Kaijalainen S, Paananen A, Simonen ML, Vuorinen T, Roivainen M.

J Clin Virol. 2010 May;48(1):49-54. doi: 10.1016/j.jcv.2010.02.002. Epub 2010 Feb 26.

PMID:
20189452
27.

Cholesterol absorption decreases after Roux-en-Y gastric bypass but not after gastric banding.

Pihlajamäki J, Grönlund S, Simonen M, Käkelä P, Moilanen L, Pääkkönen M, Pirinen E, Kolehmainen M, Kärjä V, Kainulainen S, Uusitupa M, Alhava E, Miettinen TA, Gylling H.

Metabolism. 2010 Jun;59(6):866-72. doi: 10.1016/j.metabol.2009.10.004. Epub 2009 Dec 16.

PMID:
20015521
28.

Outbreak of poliomyelitis in Finland in 1984-85 - Re-analysis of viral sequences using the current standard approach.

Simonen ML, Roivainen M, Iber J, Burns C, Hovi T.

Virus Res. 2010 Jan;147(1):91-7. doi: 10.1016/j.virusres.2009.10.012. Epub 2009 Oct 31.

PMID:
19883702
29.

Comparison of variability and sensitivity between nuclear translocation and luciferase reporter gene assays.

Unterreiner V, Ibig-Rehm Y, Simonen M, Gubler H, Gabriel D.

J Biomol Screen. 2009 Jan;14(1):59-65. doi: 10.1177/1087057108328016.

PMID:
19171921
30.

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity.

Maira SM, Stauffer F, Brueggen J, Furet P, Schnell C, Fritsch C, Brachmann S, Chène P, De Pover A, Schoemaker K, Fabbro D, Gabriel D, Simonen M, Murphy L, Finan P, Sellers W, García-Echeverría C.

Mol Cancer Ther. 2008 Jul;7(7):1851-63. doi: 10.1158/1535-7163.MCT-08-0017. Epub 2008 Jul 7.

31.

High-content assay to study protein prenylation.

Simonen M, Ibig-Rehm Y, Hofmann G, Zimmermann J, Albrecht G, Magnier M, Heidinger V, Gabriel D.

J Biomol Screen. 2008 Jul;13(6):456-67. doi: 10.1177/1087057108318757. Epub 2008 May 28.

PMID:
18509097
32.

Nogo-A-deficient mice reveal strain-dependent differences in axonal regeneration.

Dimou L, Schnell L, Montani L, Duncan C, Simonen M, Schneider R, Liebscher T, Gullo M, Schwab ME.

J Neurosci. 2006 May 24;26(21):5591-603.

33.

Hematopoietic transcription factor GATA-2 promotes upregulation of alpha globin and cell death in FL5.12 cells.

Brecht K, Simonen M, Kamke M, Heim J.

Apoptosis. 2005 Oct;10(5):1063-78.

PMID:
16151640
34.

Upregulation of alpha globin promotes apoptotic cell death in the hematopoietic cell line FL5.12.

Brecht K, Simonen M, Heim J.

Apoptosis. 2005 Oct;10(5):1043-62.

PMID:
16151639
35.

Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions.

Oertle T, van der Haar ME, Bandtlow CE, Robeva A, Burfeind P, Buss A, Huber AB, Simonen M, Schnell L, Brösamle C, Kaupmann K, Vallon R, Schwab ME.

J Neurosci. 2003 Jul 2;23(13):5393-406.

36.

Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury.

Simonen M, Pedersen V, Weinmann O, Schnell L, Buss A, Ledermann B, Christ F, Sansig G, van der Putten H, Schwab ME.

Neuron. 2003 Apr 24;38(2):201-11.

37.

A microarray-based, integrated approach to identify novel regulators of cancer drug response and apoptosis.

Brachat A, Pierrat B, Xynos A, Brecht K, Simonen M, Brüngger A, Heim J.

Oncogene. 2002 Nov 28;21(54):8361-71.

38.

Nogo-A expressed in Schwann cells impairs axonal regeneration after peripheral nerve injury.

Pot C, Simonen M, Weinmann O, Schnell L, Christ F, Stoeckle S, Berger P, Rülicke T, Suter U, Schwab ME.

J Cell Biol. 2002 Oct 14;159(1):29-35. Epub 2002 Oct 14.

39.

SH3GLB, a new endophilin-related protein family featuring an SH3 domain.

Pierrat B, Simonen M, Cueto M, Mestan J, Ferrigno P, Heim J.

Genomics. 2001 Jan 15;71(2):222-34.

PMID:
11161816
40.

Structural basis of BFL-1 for its interaction with BAX and its anti-apoptotic action in mammalian and yeast cells.

Zhang H, Cowan-Jacob SW, Simonen M, Greenhalf W, Heim J, Meyhack B.

J Biol Chem. 2000 Apr 14;275(15):11092-9.

41.

Uncoupling proteins 2 and 3 interact with members of the 14.3.3 family.

Pierrat B, Ito M, Hinz W, Simonen M, Erdmann D, Chiesi M, Heim J.

Eur J Biochem. 2000 May;267(9):2680-7.

43.

Glycosylation of rat NGF receptor ectodomain in the yeast Saccharomyces cerevisiae.

Holkeri H, Simonen M, Pummi T, Vihinen H, Makarow M.

FEBS Lett. 1996 Apr 1;383(3):255-8.

44.

The hsp150 delta-carrier confers secretion competence to the rat nerve growth factor receptor ectodomain in Saccharomyces cerevisiae.

Simonen M, Vihinen H, Jämsä E, Arumäe U, Kalkkinen N, Makarow M.

Yeast. 1996 Apr;12(5):457-66.

45.

[Biotechnology in the development of medications and vaccines].

Makarow M, Simonen M, Ulmanen I.

Duodecim. 1996;112(4):325-35. Review. Finnish. No abstract available.

PMID:
10590649
46.

Structural features of a polypeptide carrier promoting secretion of a beta-lactamase fusion protein in yeast.

Jämsä E, Holkeri H, Vihinen H, Wikström M, Simonen M, Walse B, Kalkkinen N, Paakkola J, Makarow M.

Yeast. 1995 Nov;11(14):1381-91.

PMID:
8585321
48.
49.

Dual regulation by heat and nutrient stress of the yeast HSP150 gene encoding a secretory glycoprotein.

Russo P, Simonen M, Uimari A, Teesalu T, Makarow M.

Mol Gen Genet. 1993 May;239(1-2):273-80.

PMID:
8510655
50.

Protein secretion in Bacillus species.

Simonen M, Palva I.

Microbiol Rev. 1993 Mar;57(1):109-37. Review.

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