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Building more accurate decision trees with the additive tree.

Luna JM, Gennatas ED, Ungar LH, Eaton E, Diffenderfer ES, Jensen ST, Simone CB 2nd, Friedman JH, Solberg TD, Valdes G.

Proc Natl Acad Sci U S A. 2019 Sep 16. pii: 201816748. doi: 10.1073/pnas.1816748116. [Epub ahead of print]


Radiologic Considerations And Standardization Of Malignant Pleural Mesothelioma (MPM) Imaging Within Clinical Trials: Consensus Statement From The NCI Thoracic Malignancy Steering Committee - International Association For The Study Of Lung Cancer - Mesothelioma Applied Research Foundation Clinical Trials Planning Meeting.

Gill RR, Tsao AS, Kindler HL, Richards WG, Armato SG 3rd, Francis RJ, Gomez DR, Dahlberg S, Rimner A, Simone CB 2nd, de Perrot M, Blumenthal G, Adjei AA, Bueno R, Harpole DH Jr, Hesdorffer M, Hirsch FR, Pass HI, Yorke E, Rosenzweig K, Burt B, Fennell DA, Lindwasser W, Malik S, Peikert T, Mansfield AS, Salgia R, Yang H, Rusch VW, Nowak AK.

J Thorac Oncol. 2019 Aug 27. pii: S1556-0864(19)30695-1. doi: 10.1016/j.jtho.2019.08.012. [Epub ahead of print]


Clinical Outcomes of the HIV Protease Inhibitor Nelfinavir With Concurrent Chemoradiotherapy for Unresectable Stage IIIA/IIIB Non-Small Cell Lung Cancer: A Phase 1/2 Trial.

Rengan R, Mick R, Pryma DA, Lin LL, Christodouleas J, Plastaras JP, Simone CB 2nd, Gupta AK, Evans TL, Stevenson JP, Langer CJ, Kucharczuk J, Friedberg J, Lam S, Patsch D, Hahn SM, Maity A.

JAMA Oncol. 2019 Aug 22. doi: 10.1001/jamaoncol.2019.2095. [Epub ahead of print]


Early palliative care and the opioid crisis: ten pragmatic steps towards a more rational use of opioids.

Gaertner J, Boehlke C, Simone CB 2nd, Hui D.

Ann Palliat Med. 2019 Aug 16. pii: apm.2019.08.01. doi: 10.21037/apm.2019.08.01. [Epub ahead of print]


Stereotactic body radiation therapy versus multi-fraction radiation therapy for bone metastases.

Simone CB 2nd.

Ann Palliat Med. 2019 Jul 25. pii: apm.2019.07.06. doi: 10.21037/apm.2019.07.06. [Epub ahead of print] No abstract available.


One & done: treating cord compression with single-fraction radiation therapy.

Yerramilli D, Simone CB 2nd, Dharmarajan KV.

Ann Palliat Med. 2019 Aug 5. pii: apm.2019.07.05. doi: 10.21037/apm.2019.07.05. [Epub ahead of print] No abstract available.


Design of hybrid molecules as antimycobacterial compounds: Synthesis of isoniazid-naphthoquinone derivatives and their activity against susceptible and resistant strains of Mycobacterium tuberculosis.

Reis WJ, Bozzi ÍAO, Ribeiro MF, Halicki PCB, Ferreira LA, Almeida da Silva PE, Ramos DF, de Simone CA, da Silva Júnior EN.

Bioorg Med Chem. 2019 Sep 15;27(18):4143-4150. doi: 10.1016/j.bmc.2019.07.045. Epub 2019 Jul 27.


Annals of Palliative Medicine earns its first official impact factor.

Simone CB 2nd.

Ann Palliat Med. 2019 Jul;8(3):352-354. doi: 10.21037/apm.2019.07.03. No abstract available.


FOXO3 on the Road to Longevity: Lessons From SNPs and Chromatin Hubs.

Sanese P, Forte G, Disciglio V, Grossi V, Simone C.

Comput Struct Biotechnol J. 2019 Jun 13;17:737-745. doi: 10.1016/j.csbj.2019.06.011. eCollection 2019. Review.


Germline pathogenic variant in PIK3CA leading to symmetrical overgrowth with marked macrocephaly and mild global developmental delay.

Zollino M, Ranieri C, Grossi V, Leoni C, Lattante S, Mazzà D, Simone C, Resta N.

Mol Genet Genomic Med. 2019 Aug;7(8):e845. doi: 10.1002/mgg3.845. Epub 2019 Jul 9.


Surgery after chemoradiotherapy in patients with stage III (N2 or N3, excluding T4) non-small-cell lung cancer: a systematic review.

Swaminath A, Vella ET, Ramchandar K, Robinson A, Simone C, Sun A, Ung YC, Yasufuku K, Ellis PM.

Curr Oncol. 2019 Jun;26(3):e398-e404. doi: 10.3747/co.26.4549. Epub 2019 Jun 1. Review.


Stereotactic body radiation therapy versus surgery for early stage non-small cell lung cancer: clearing a path through an evolving treatment landscape.

Choi JI, Simone CB 2nd.

J Thorac Dis. 2019 May;11(Suppl 9):S1360-S1365. doi: 10.21037/jtd.2019.03.91. No abstract available.


Proton Beam Therapy and Immune Checkpoint Inhibitors in Malignant Pleural Mesothelioma.

McCusker MG, Scilla KA, Simone CB 2nd, Sachdeva A, Miller KD, Burke AP, Rolfo C.

J Thorac Oncol. 2019 Sep;14(9):e185-e187. doi: 10.1016/j.jtho.2019.05.013. Epub 2019 Jun 22. No abstract available.


Management of Clinically Lymph Node-Positive Malignant Pleural Mesothelioma.

Verma V, Wegner RE, Adeberg S, Horne ZD, Grover S, Friedberg JS, Simone CB 2nd.

Semin Thorac Cardiovasc Surg. 2019 Jun 19. pii: S1043-0679(19)30177-7. doi: 10.1053/j.semtcvs.2019.06.004. [Epub ahead of print]


Early Detection of Recurrence in Patients With Locally Advanced Non-Small-Cell Lung Cancer via Circulating Tumor Cell Analysis.

Chinniah C, Aguarin L, Cheng P, Decesaris C, Cutillo A, Berman AT, Frick M, Doucette A, Cengel KA, Levin W, Hahn S, Dorsey JF, Simone CB 2nd, Kao GD.

Clin Lung Cancer. 2019 Sep;20(5):384-390.e2. doi: 10.1016/j.cllc.2019.04.011. Epub 2019 May 4.


A case of guttate psoriasis during treatment with dupilumab.

Gori N, Caldarola G, Pirro F, De Simone C, Peris K.

Dermatol Ther. 2019 Jun 19:e12998. doi: 10.1111/dth.12998. [Epub ahead of print] No abstract available.


Emerging treatment options for the treatment of moderate to severe plaque psoriasis and psoriatic arthritis: evaluating bimekizumab and its therapeutic potential.

Chiricozzi A, De Simone C, Fossati B, Peris K.

Psoriasis (Auckl). 2019 May 24;9:29-35. doi: 10.2147/PTT.S179283. eCollection 2019.


PsA-Disk, a novel visual instrument to evaluate psoriatic arthritis in psoriatic patients: an Italian derma-rheuma multicentre study.

Chimenti MS, Esposito M, Graceffa D, Teoli M, Peluso G, Birra D, Moretta G, Galossi A, Carboni V, Sensi F, Mazzotta A, Caccavale R, Bernardini N, Sessa P, Richetta A, Del Duca E, Urbani S, Persechino S, De Simone C, Bonifati C, Gremese E, Peris K, Perricone R.

Ther Adv Chronic Dis. 2019 May 14;10:2040622319847056. doi: 10.1177/2040622319847056. eCollection 2019.


The Use of Radiation Therapy for the Treatment of Malignant Pleural Mesothelioma: Expert Opinion from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation.

Gomez DR, Rimner A, Simone CB 2nd, Cho BCJ, de Perrot M, Adjei AA, Bueno R, Gill RR, Harpole DH Jr, Hesdorffer M, Hirsch FR, Jackson AA, Pass HI, Rice DC, Rusch VW, Tsao AS, Yorke E, Rosenzweig K.

J Thorac Oncol. 2019 Jul;14(7):1172-1183. doi: 10.1016/j.jtho.2019.03.030. Epub 2019 May 22. Review.


Lymphangitic carcinomatosis: A common radiographic manifestation of local failure following extended pleurectomy/decortication in patients with malignant pleural mesothelioma.

Berger I, Cengel KA, Simone CB 2nd, Alley EW, Roshkovan L, Haas AR, Patel AM, Khalid U, Culligan MJ, McNulty S, Singhal S, Friedberg JS, Katz SI.

Lung Cancer. 2019 Jun;132:94-98. doi: 10.1016/j.lungcan.2019.03.026. Epub 2019 Mar 26.


The role of radiation treatment in pleural mesothelioma: Highlights of the 14th International Conference of the International mesothelioma interest group.

MacRae RM, Ashton M, Lauk O, Wilson W, O'Rourke N, Simone CB 2nd, Rimner A.

Lung Cancer. 2019 Jun;132:24-27. doi: 10.1016/j.lungcan.2019.03.023. Epub 2019 Mar 31. Review.


Quantification of global lung inflammation using volumetric 18F-FDG PET/CT parameters in locally advanced non-small-cell lung cancer patients treated with concurrent chemoradiotherapy: a comparison of photon and proton radiation therapy.

Rice SR, Saboury B, Houshmand S, Salavati A, Kalbasi A, Goodman CR, Werner TJ, Vujaskovic Z, Simone CB 2nd, Alavi A.

Nucl Med Commun. 2019 Jun;40(6):618-625. doi: 10.1097/MNM.0000000000000997.


A rare case of bullous Sweet's syndrome in a patient with inactive ulcerative colitis.

Esposito I, Fossati B, Peris K, De Simone C.

J Eur Acad Dermatol Venereol. 2019 May 13. doi: 10.1111/jdv.15674. [Epub ahead of print] No abstract available.


First-ever Abscopal Effect after Palliative Radiotherapy and Immuno-gene Therapy for Malignant Pleural Mesothelioma.

Barsky AR, Cengel KA, Katz SI, Sterman DH, Simone CB 2nd.

Cureus. 2019 Feb 20;11(2):e4102. doi: 10.7759/cureus.4102.


Clinical significance of pretreatment tumor growth rate for locally advanced non-small cell lung cancer.

Osorio B, Yegya-Raman N, Kim S, Simone CB 2nd, Theodorou Ross C, Deek MP, Gaines D, Zou W, Lin L, Malhotra J, Nie K, Aisner J, Jabbour SK.

Ann Transl Med. 2019 Mar;7(5):95. doi: 10.21037/atm.2019.02.14.


Management of Malignant Pleural Mesothelioma in the Elderly Population.

Verma V, Wegner RE, Ludmir EB, Hasan S, Colonias A, Grover S, Friedberg JS, Simone CB 2nd.

Ann Surg Oncol. 2019 Aug;26(8):2357-2366. doi: 10.1245/s10434-019-07351-6. Epub 2019 Apr 22.


A minimum of two years of undertreated primary hypothyroidism, as a result of drug-induced malabsorption of l-thyroxine, may have metabolic and cardiovascular consequences.

Benvenga S, Pantano R, Saraceno G, Lipari L, Alibrando A, Inferrera S, Pantano G, Simone G, Tamà S, Scoglio R, Ursino MG, Simone C, Catalano A, Alecci U.

J Clin Transl Endocrinol. 2019 Apr 10;16:100189. doi: 10.1016/j.jcte.2019.100189. eCollection 2019 Jun.


Moderate-to-severe psoriasis and pregnancy: impact on fertility, pregnancy outcome and treatment perspectives.

De Simone C, Caldarola G, Moretta G, Piscitelli L, Ricceri F, Prignano F.

G Ital Dermatol Venereol. 2019 Jun;154(3):305-314. doi: 10.23736/S0392-0488.18.06255-7.


Skin diseases in pregnancy: a challenge for dermatologists.

Cozzani E, De Simone C.

G Ital Dermatol Venereol. 2019 Jun;154(3):254-255. doi: 10.23736/S0392-0488.19.06315-6. No abstract available.


Chemotherapy Versus Supportive Care for Unresected Malignant Pleural Mesothelioma.

Verma V, Wegner RE, Brooks ED, Miccio JA, Kann BH, Finley GG, Raj MS, Grover S, Mohindra P, Simone CB 2nd.

Clin Lung Cancer. 2019 Jul;20(4):263-269. doi: 10.1016/j.cllc.2019.03.003. Epub 2019 Mar 26.


Ibrutinib-associated palmo-plantar fissures in a patient with Chronic Lymphocytic Leukaemia: a novel cutaneous adverse event.

Sollena P, Mannino M, Laurenti L, De Simone C, Peris K.

J Eur Acad Dermatol Venereol. 2019 Sep;33(9):e342-e344. doi: 10.1111/jdv.15632. Epub 2019 Apr 25. No abstract available.


Annular elastolytic giant cell granuloma following herpes zoster infection.

Gori N, Caldarola G, De Simone C, Moretta G, Peris K.

J Eur Acad Dermatol Venereol. 2019 Sep;33(9):e334-e335. doi: 10.1111/jdv.15627. Epub 2019 Apr 29. No abstract available.


Prevalence of cutaneous comorbidities in psoriatic patients and their impact on quality of life.

Caldarola G, De Simone C, Talamonti M, Moretta G, Fossati B, Bianchi L, Fargnoli MC, Peris K.

Eur J Dermatol. 2019 Apr 1;29(2):192-196. doi: 10.1684/ejd.2019.3529.


Paradoxical Skin Reactions to Biologics in Patients With Rheumatologic Disorders.

Garcovich S, De Simone C, Genovese G, Berti E, Cugno M, Marzano AV.

Front Pharmacol. 2019 Mar 26;10:282. doi: 10.3389/fphar.2019.00282. eCollection 2019.


Predicting radiation pneumonitis in locally advanced stage II-III non-small cell lung cancer using machine learning.

Luna JM, Chao HH, Diffenderfer ES, Valdes G, Chinniah C, Ma G, Cengel KA, Solberg TD, Berman AT, Simone CB 2nd.

Radiother Oncol. 2019 Apr;133:106-112. doi: 10.1016/j.radonc.2019.01.003. Epub 2019 Jan 23.


Lenvatinib plus pembrolizumab in patients with advanced endometrial cancer: an interim analysis of a multicentre, open-label, single-arm, phase 2 trial.

Makker V, Rasco D, Vogelzang NJ, Brose MS, Cohn AL, Mier J, Di Simone C, Hyman DM, Stepan DE, Dutcus CE, Schmidt EV, Guo M, Sachdev P, Shumaker R, Aghajanian C, Taylor M.

Lancet Oncol. 2019 May;20(5):711-718. doi: 10.1016/S1470-2045(19)30020-8. Epub 2019 Mar 25.


Patterns of Care and Survival in Stage III NSCLC Among Black and Latino Patients Compared With White Patients.

Vyfhuis MAL, Bentzen SM, Molitoris JK, Diwanji T, Badiyan S, Grover S, Adebamowo CA, Simone CB 2nd, Mohindra P.

Clin Lung Cancer. 2019 Jul;20(4):248-257.e4. doi: 10.1016/j.cllc.2019.02.015. Epub 2019 Feb 28.


Chasing the FOXO3: Insights into Its New Mitochondrial Lair in Colorectal Cancer Landscape.

Grossi V, Fasano C, Celestini V, Lepore Signorile M, Sanese P, Simone C.

Cancers (Basel). 2019 Mar 23;11(3). pii: E414. doi: 10.3390/cancers11030414. Review.


Downstream Effect of a Proton Treatment Center on an Academic Medical Center.

Remick JS, Bentzen SM, Simone CB 2nd, Nichols E, Suntharalingam M, Regine WF.

Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):756-764. doi: 10.1016/j.ijrobp.2019.03.016. Epub 2019 Mar 15.


AAR-RT - A system for auto-contouring organs at risk on CT images for radiation therapy planning: Principles, design, and large-scale evaluation on head-and-neck and thoracic cancer cases.

Wu X, Udupa JK, Tong Y, Odhner D, Pednekar GV, Simone CB 2nd, McLaughlin D, Apinorasethkul C, Apinorasethkul O, Lukens J, Mihailidis D, Shammo G, James P, Tiwari A, Wojtowicz L, Camaratta J, Torigian DA.

Med Image Anal. 2019 May;54:45-62. doi: 10.1016/ Epub 2019 Jan 29.


A nomogram for the prediction of cerebrovascular disease among patients with brain necrosis after radiotherapy for nasopharyngeal carcinoma.

Cai J, Cheng J, Li H, Lin WJ, Li Y, Zhuo X, Huang X, Simone CB 2nd, Aronow WS, Chow ELW, Tang Y.

Radiother Oncol. 2019 Mar;132:34-41. doi: 10.1016/j.radonc.2018.11.008. Epub 2018 Dec 21.


Society for Palliative Radiation Oncology: report from the Fifth Annual Meeting (2018).

Johnstone C, Martin E, Mitin T, Tseng Y, Simone CB 2nd.

Ann Palliat Med. 2019 Feb;8(Suppl 1):S61-S63. doi: 10.21037/apm.2019.02.01. No abstract available.


The importance of nurses in the care of and research advancements for patients with advanced diseases.

Simone CB 2nd.

Ann Palliat Med. 2019 Feb;8(Suppl 1):S1-S2. doi: 10.21037/apm.2019.01.04. No abstract available.


Cancer cachexia: definitions, outcomes, and treatments.

Simone CB 2nd.

Ann Palliat Med. 2019 Jan;8(1):E1-E3. doi: 10.21037/apm.2019.02.03. No abstract available.


Clinical Outcomes of Patients With Recurrent Lung Cancer Reirradiated With Proton Therapy on the Proton Collaborative Group and University of Florida Proton Therapy Institute Prospective Registry Studies.

Badiyan SN, Rutenberg MS, Hoppe BS, Mohindra P, Larson G, Hartsell WF, Tsai H, Zeng J, Rengan R, Glass E, Katz S, Vargas C, Feigenberg SJ, Simone CB 2nd.

Pract Radiat Oncol. 2019 Jul - Aug;9(4):280-288. doi: 10.1016/j.prro.2019.02.008. Epub 2019 Feb 23.


Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies.

Kaiser A, Eley JG, Onyeuku NE, Rice SR, Wright CC, McGovern NE, Sank M, Zhu M, Vujaskovic Z, Simone CB 2nd, Hussain A.

J Vis Exp. 2019 Feb 6;(144). doi: 10.3791/58372.


Approaches to stereotactic body radiation therapy for large (≥5 centimeter) non-small cell lung cancer.

Verma V, Simone CB 2nd.

Transl Lung Cancer Res. 2019 Feb;8(1):70-77. doi: 10.21037/tlcr.2018.06.10. Review.


Optimizing immobilization, margins, and imaging for lung stereotactic body radiation therapy.

Molitoris JK, Diwanji T, Snider JW 3rd, Mossahebi S, Samanta S, Onyeuku N, Mohindra P, Choi JI, Simone CB 2nd.

Transl Lung Cancer Res. 2019 Feb;8(1):24-31. doi: 10.21037/tlcr.2018.09.25. Review.


Empiric Radiotherapy for Lung Cancer Collaborative Group multi-institutional evidence-based guidelines for the use of empiric stereotactic body radiation therapy for non-small cell lung cancer without pathologic confirmation.

Berman AT, Jabbour SK, Vachani A, Robinson C, Choi JI, Mohindra P, Rengan R, Bradley J, Simone CB 2nd.

Transl Lung Cancer Res. 2019 Feb;8(1):5-14. doi: 10.21037/tlcr.2018.12.12. Review.


The current and future faces of stereotactic body radiation therapy for thoracic malignancies.

Choi JI, Simone CB 2nd.

Transl Lung Cancer Res. 2019 Feb;8(1):1-4. doi: 10.21037/tlcr.2018.12.10. No abstract available.

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