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p53 overexpression is a prognosticator of poor outcome in esophageal cancer.

Melling N, Norrenbrock S, Kluth M, Simon R, Hube-Magg C, Steurer S, Hinsch A, Burandt E, Jacobsen F, Wilczak W, Quaas A, Bockhorn M, Grupp K, Tachezy M, Izbicki J, Sauter G, Gebauer F.

Oncol Lett. 2019 Apr;17(4):3826-3834. doi: 10.3892/ol.2019.10020. Epub 2019 Feb 6.


Classification of Sonar Targets in Air: A Neural Network Approach.

Kroh PK, Simon R, Rupitsch SJ.

Sensors (Basel). 2019 Mar 7;19(5). pii: E1176. doi: 10.3390/s19051176.


Evaluation and active treatment versus active surveillance of localized prostate cancer in renal transplant patients in the era of low and very low risk prostate cancer.

Aminsharifi A, Simon R, Polascik TJ, Robertson CN, Sudan DL, Collins BH, Moul JW.

J Urol. 2019 Mar 5:101097JU0000000000000207. doi: 10.1097/JU.0000000000000207. [Epub ahead of print]


Aberrant expression of the microtubule-associated protein tau is an independent prognostic feature in prostate cancer.

Schroeder C, Grell J, Hube-Magg C, Kluth M, Lang D, Simon R, Höflmayer D, Minner S, Burandt E, Clauditz TS, Büscheck F, Jacobsen F, Huland H, Graefen M, Schlomm T, Sauter G, Steurer S.

BMC Cancer. 2019 Mar 1;19(1):193. doi: 10.1186/s12885-019-5390-1.


Impact of branching on the conformational heterogeneity of the lipopolysaccharide from Klebsiella pneumoniae: Implications for vaccine design.

Aytenfisu AH, Simon R, MacKerell AD Jr.

Carbohydr Res. 2019 Feb 18;475:39-47. doi: 10.1016/j.carres.2019.02.003. [Epub ahead of print]


Cofactor Analogues as Active Site Probes in Lysine Acetyltransferases.

Simon RP, Rumpf T, Linkuviene V, Matulis D, Akhtar A, Jung M.

J Med Chem. 2019 Mar 14;62(5):2582-2597. doi: 10.1021/acs.jmedchem.8b01887. Epub 2019 Mar 6.


Patterns of TIGIT Expression in Lymphatic Tissue, Inflammation, and Cancer.

Blessin NC, Simon R, Kluth M, Fischer K, Hube-Magg C, Li W, Makrypidi-Fraune G, Wellge B, Mandelkow T, Debatin NF, Höflmayer D, Lennartz M, Sauter G, Izbicki JR, Minner S, Büscheck F, Uhlig R, Dum D, Krech T, Luebke AM, Wittmer C, Jacobsen F, Burandt EC, Steurer S, Wilczak W, Hinsch A.

Dis Markers. 2019 Jan 10;2019:5160565. doi: 10.1155/2019/5160565. eCollection 2019.


D3Oncoprint: Stand-Alone Software to Visualize and Dynamically Explore Annotated Genomic Mutation Files.

Palmisano A, Zhao Y, Simon RM.

JCO Clin Cancer Inform. 2018 Dec;2:1-9. doi: 10.1200/CCI.17.00050.


5q21 deletion is often heterogeneous in prostate cancer.

Kluth M, Al Kilani Z, Özden C, Hussein K, Frogh S, Möller-Koop C, Burandt E, Steurer S, Büscheck F, Jacobsen F, Luebke AM, Minner S, Tsourlakis MC, Hoeflmayer D, Wittmer C, Schlomm T, Sauter G, Simon R, Wilczak W.

Genes Chromosomes Cancer. 2019 Jan 9. doi: 10.1002/gcc.22730. [Epub ahead of print]


Differences in the upslope of the precordial body surface ECG T wave reflect right to left dispersion of repolarization in the intact human heart.

Srinivasan NT, Orini M, Providencia R, Simon R, Lowe M, Segal OR, Chow AW, Schilling RJ, Hunter RJ, Taggart P, Lambiase PD.

Heart Rhythm. 2018 Dec 12. pii: S1547-5271(18)31261-X. doi: 10.1016/j.hrthm.2018.12.006. [Epub ahead of print]


High expression of class III β-tubulin in upper gastrointestinal cancer types.

Höflmayer D, Öztürk E, Schroeder C, Hube-Magg C, Blessin NC, Simon R, Lang DS, Neubauer E, Göbel C, Heinrich MC, Fraune C, Möller K, Armbrust M, Freytag M, Hinsch A, Lühr C, Noack M, Reiswich V, Weidemann S, Bockhorn M, Perez D, Izbicki JR, Sauter G, Jacobsen F.

Oncol Lett. 2018 Dec;16(6):7139-7145. doi: 10.3892/ol.2018.9502. Epub 2018 Sep 25.


Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.

Gerhauser C, Favero F, Risch T, Simon R, Feuerbach L, Assenov Y, Heckmann D, Sidiropoulos N, Waszak SM, Hübschmann D, Urbanucci A, Girma EG, Kuryshev V, Klimczak LJ, Saini N, Stütz AM, Weichenhan D, Böttcher LM, Toth R, Hendriksen JD, Koop C, Lutsik P, Matzk S, Warnatz HJ, Amstislavskiy V, Feuerstein C, Raeder B, Bogatyrova O, Schmitz EM, Hube-Magg C, Kluth M, Huland H, Graefen M, Lawerenz C, Henry GH, Yamaguchi TN, Malewska A, Meiners J, Schilling D, Reisinger E, Eils R, Schlesner M, Strand DW, Bristow RG, Boutros PC, von Kalle C, Gordenin D, Sültmann H, Brors B, Sauter G, Plass C, Yaspo ML, Korbel JO, Schlomm T, Weischenfeldt J.

Cancer Cell. 2018 Dec 10;34(6):996-1011.e8. doi: 10.1016/j.ccell.2018.10.016.


Enhancing Base Excision Repair of Mitochondrial DNA to Reduce Ischemic Injury Following Reperfusion.

Simon R, Meller R, Yang T, Pearson A, Wilson G.

Transl Stroke Res. 2018 Dec 8. doi: 10.1007/s12975-018-0680-5. [Epub ahead of print]


Upregulation of centromere protein F is linked to aggressive prostate cancers.

Göbel C, Özden C, Schroeder C, Hube-Magg C, Kluth M, Möller-Koop C, Neubauer E, Hinsch A, Jacobsen F, Simon R, Sauter G, Michl U, Pehrke D, Huland H, Graefen M, Schlomm T, Luebke AM.

Cancer Manag Res. 2018 Nov 9;10:5491-5504. doi: 10.2147/CMAR.S165630. eCollection 2018.


Expression of the immune checkpoint receptor TIGIT in Hodgkin's lymphoma.

Li W, Blessin NC, Simon R, Kluth M, Fischer K, Hube-Magg C, Makrypidi-Fraune G, Wellge B, Mandelkow T, Debatin NF, Pott L, Höflmayer D, Lennartz M, Sauter G, Izbicki JR, Minner S, Büscheck F, Uhlig R, Dum D, Krech T, Luebke AM, Wittmer C, Jacobsen F, Burandt E, Steurer S, Wilczak W, Hinsch A.

BMC Cancer. 2018 Dec 4;18(1):1209. doi: 10.1186/s12885-018-5111-1.


Deletion of 3p13 is a late event linked to progression of TMPRSS2:ERG fusion prostate cancer.

Kluth M, Volta H, Hussein M, Taskin B, Frogh S, Möller-Koop C, Büscheck F, Jacobsen F, Tsourlakis MC, Lübke AM, Hinsch A, Clauditz T, Graefen M, Heinzer H, Huland H, Minner S, Sauter G, Wilczak W, Schlomm T, Simon R.

Cancer Manag Res. 2018 Nov 19;10:5909-5917. doi: 10.2147/CMAR.S172637. eCollection 2018.


Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer.

Lange T, Oh-Hohenhorst SJ, Joosse SA, Pantel K, Hahn O, Gosau T, Dyshlovoy SA, Wellbrock J, Feldhaus S, Maar H, Gehrcke R, Kluth M, Simon R, Schlomm T, Huland H, Schumacher U.

Sci Rep. 2018 Dec 3;8(1):17535. doi: 10.1038/s41598-018-35695-8.


Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells.

Hadi T, Boytard L, Silvestro M, Alebrahim D, Jacob S, Feinstein J, Barone K, Spiro W, Hutchison S, Simon R, Rateri D, Pinet F, Fenyo D, Adelman M, Moore KJ, Eltzschig HK, Daugherty A, Ramkhelawon B.

Nat Commun. 2018 Nov 27;9(1):5022. doi: 10.1038/s41467-018-07495-1.


Bromocriptine Use in Peripartum Cardiomyopathy: Review of Cases.

Simon R, Yang S, Hameed AB.

AJP Rep. 2018 Oct;8(4):e335-e342. doi: 10.1055/s-0038-1675832. Epub 2018 Nov 21.


J-Pouch Prolapse as a Late Complication of Restorative Proctocolectomy.

Simon R, Hollister K, Stanley JD, Lorenzo-Rivero S.

Am Surg. 2018 Sep 1;84(9):e383-e384. No abstract available.


Loss of CCAAT-enhancer-binding protein alpha (CEBPA) is linked to poor prognosis in PTEN deleted and TMPRSS2:ERG fusion type prostate cancers.

Minner S, Lutz J, Hube-Magg C, Kluth M, Simon R, Höflmayer D, Burandt E, Tsourlakis MC, Sauter G, Büscheck F, Wilczak W, Steurer S, Schlomm T, Huland H, Graefen M, Haese A, Heinzer H, Jacobsen F, Hinsch A, Poos A, Oswald M, Rippe K, König R, Schroeder C.

Prostate. 2019 Feb;79(3):302-311. doi: 10.1002/pros.23736. Epub 2018 Nov 14.


Neuraminidase 1-mediated desialylation of the mucin 1 ectodomain releases a decoy receptor that protects against Pseudomonas aeruginosa lung infection.

Lillehoj EP, Guang W, Hyun SW, Liu A, Hegerle N, Simon R, Cross AS, Ishida H, Luzina IG, Atamas SP, Goldblum SE.

J Biol Chem. 2019 Jan 11;294(2):662-678. doi: 10.1074/jbc.RA118.006022. Epub 2018 Nov 14.


Reduced RBM3 expression is associated with aggressive tumor features in esophageal cancer but not significantly linked to patient outcome.

Grupp K, Hofmann B, Kutup A, Bachmann K, Bogoevski D, Melling N, Uzunoglu FG, El Gammal AT, Koop C, Simon R, Steurer S, Krech T, Burdak-Rothkamm S, Jacobsen F, Sauter G, Izbicki J, Wilczak W.

BMC Cancer. 2018 Nov 12;18(1):1106. doi: 10.1186/s12885-018-5032-z.


Clopidogrel Desensitization: Background and Recommendations for Use of a Rapid (4 Hour) Protocol.

Bulva J, Simon RA.

Curr Vasc Pharmacol. 2019;17(2):113-118. doi: 10.2174/1570161116666181031101930.


The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel.

Monks A, Zhao Y, Hose C, Hamed H, Krushkal J, Fang J, Sonkin D, Palmisano A, Polley EC, Fogli LK, Konaté MM, Miller SB, Simpson MA, Voth AR, Li MC, Harris E, Wu X, Connelly JW, Rapisarda A, Teicher BA, Simon R, Doroshow JH.

Cancer Res. 2018 Dec 15;78(24):6807-6817. doi: 10.1158/0008-5472.CAN-18-0989. Epub 2018 Oct 24.


Pharmacological Modulation of Right Ventricular Endocardial-Epicardial Gradients in Brugada Syndrome.

Bhar-Amato J, Finlay M, Santos D, Orini M, Chaubey S, Vyas V, Taggart P, Grace AA, Huang CL, Ben Simon R, Tinker A, Lambiase PD.

Circ Arrhythm Electrophysiol. 2018 Sep;11(9):e006330. doi: 10.1161/CIRCEP.118.006330.


[Change in paradigm in the treatment of pediatric acquired bone marrow failure syndromes in Hungary].

Kállay K, Csomor J, Ádám E, Bödör C, Kassa C, Simon R, Kovács G, Péter G, Ottóffy G, Bartyik K, Kiss C, Masát P, Réti M, Tóth B, Kriván G.

Orv Hetil. 2018 Oct;159(42):1710-1719. doi: 10.1556/650.2018.31171. Hungarian.


High concordance of TMPRSS-ERG fusion between primary prostate cancer and its lymph node metastases.

Brandi F, Grupp K, Hube-Magg C, Kluth M, Lang D, Minner S, Möller-Koop C, Graefen M, Heinzer H, Tsourlakis MC, Wittmer C, Jacobsen F, Huland H, Steurer S, Lebok P, Hinsch A, Wilczak W, Schlomm T, Simon R.

Oncol Lett. 2018 Nov;16(5):6238-6244. doi: 10.3892/ol.2018.9417. Epub 2018 Sep 7.


Aberrant expression of membranous carbonic anhydrase IX (CAIX) is associated with unfavorable disease course in papillary and clear cell renal cell carcinoma.

Büscheck F, Fraune C, Simon R, Kluth M, Hube-Magg C, Möller-Koop C, Shadanpour N, Bannenberg C, Eichelberg C, Höflmayer D, Clauditz T, Wittmer C, Wilczak W, Sauter G, Fisch M, Rink M, Eichenauer T.

Urol Oncol. 2018 Dec;36(12):531.e19-531.e25. doi: 10.1016/j.urolonc.2018.08.015. Epub 2018 Oct 12.


Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness.

Kari V, Mansour WY, Raul SK, Baumgart SJ, Mund A, Grade M, Sirma H, Simon R, Will H, Dobbelstein M, Dikomey E, Johnsen SA.

EMBO Rep. 2018 Oct;19(10). pii: e46783. doi: 10.15252/embr.201846783. No abstract available.


Physical Therapists' Use and Alteration of Standardized Assessments of Motor Function in Children.

Fay D, Brock E, Peneton S, Simon R, Splan M, Sullivan L, Weiler A.

Pediatr Phys Ther. 2018 Oct;30(4):318-325. doi: 10.1097/PEP.0000000000000532.


The 2-Level Experience of Interlaminar Stabilization: 5-Year Follow-Up of a Prospective, Randomized Clinical Experience Compared to Fusion for the Sustainable Management of Spinal Stenosis.

Simon RB, Dowe C, Grinberg S, Cammisa FP Jr, Abjornson C.

Int J Spine Surg. 2018 Aug 31;12(4):419-427. doi: 10.14444/5050. eCollection 2018 Aug.


Evaluation of NT-ProBNP as a marker of the volume status of neurosurgical patients developing hyponatremia and natriuresis: A pilot study.

Tobin G, Chacko AG, Simon R.

Neurol India. 2018 Sep-Oct;66(5):1383-1388. doi: 10.4103/0028-3886.241401.


Identification of a High-Level MET Amplification in CTCs and cfTNA of an ALK-Positive NSCLC Patient Developing Evasive Resistance to Crizotinib.

Berger LA, Janning M, Velthaus JL, Ben-Batalla I, Schatz S, Falk M, Iglauer P, Simon R, Cao R, Forcato C, Manaresi N, Bramlett K, Buson G, Hanssen A, Tiemann M, Sauter G, Bokemeyer C, Riethdorf S, Reck M, Pantel K, Wikman H, Loges S.

J Thorac Oncol. 2018 Dec;13(12):e243-e246. doi: 10.1016/j.jtho.2018.08.2025. Epub 2018 Sep 8. No abstract available.


Development of a broad spectrum glycoconjugate vaccine to prevent wound and disseminated infections with Klebsiella pneumoniae and Pseudomonas aeruginosa.

Hegerle N, Choi M, Sinclair J, Amin MN, Ollivault-Shiflett M, Curtis B, Laufer RS, Shridhar S, Brammer J, Toapanta FR, Holder IA, Pasetti MF, Lees A, Tennant SM, Cross AS, Simon R.

PLoS One. 2018 Sep 6;13(9):e0203143. doi: 10.1371/journal.pone.0203143. eCollection 2018.


Calculated Decisions: Wound Closure Classification

Kim J, Simon R.

Pediatr Emerg Med Pract. 2018 Sep 1;14(Suppl 10):1-3.


Enhancing and Extending Biological Performance and Resilience.

Leak RK, Calabrese EJ, Kozumbo WJ, Gidday JM, Johnson TE, Mitchell JR, Ozaki CK, Wetzker R, Bast A, Belz RG, Bøtker HE, Koch S, Mattson MP, Simon RP, Jirtle RL, Andersen ME.

Dose Response. 2018 Aug 15;16(3):1559325818784501. doi: 10.1177/1559325818784501. eCollection 2018 Jul-Sep. Review.


Author Correction: Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer.

Heumann A, Kaya Ö, Burdelski C, Hube-Magg C, Kluth M, Lang DS, Simon R, Beyer B, Thederan I, Sauter G, Izbicki JR, Luebke AM, Hinsch A, Jacobsen F, Wittmer C, Büscheck F, Höflmayer D, Minner S, Tsourlakis MC, Schlomm T, Wilczak W.

Sci Rep. 2018 Aug 21;8(1):12821. doi: 10.1038/s41598-018-30975-9.


Adherence to guidelines in requesting Oncotype DX in a publicly funded health care system.

Martel S, Lambertini M, Simon R, Matte C, Prady C.

Curr Oncol. 2018 Aug;25(4):e311-e318. doi: 10.3747/co.25.3965. Epub 2018 Aug 14.


Immunogenicity and Induction of Functional Antibodies in Rabbits Immunized with a Trivalent Typhoid-Invasive Nontyphoidal Salmonella Glycoconjugate Formulation.

Baliban SM, Allen JC, Curtis B, Amin MN, Lees A, Rao RN, Naidu G, Venkatesan R, Rao DY, Mohan VK, Ella KM, Levine MM, Simon R.

Molecules. 2018 Jul 17;23(7). pii: E1749. doi: 10.3390/molecules23071749.


Teaching installation and use of child passenger safety restraints.

Giannakakos AR, Vladescu JC, Simon R.

J Appl Behav Anal. 2018 Oct;51(4):915-923. doi: 10.1002/jaba.493. Epub 2018 Jul 13.


BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells.

Lessel D, Gehbauer C, Bramswig NC, Schluth-Bolard C, Venkataramanappa S, van Gassen KLI, Hempel M, Haack TB, Baresic A, Genetti CA, Funari MFA, Lessel I, Kuhlmann L, Simon R, Liu P, Denecke J, Kuechler A, de Kruijff I, Shoukier M, Lek M, Mullen T, Lüdecke HJ, Lerario AM, Kobbe R, Krieger T, Demeer B, Lebrun M, Keren B, Nava C, Buratti J, Afenjar A, Shinawi M, Guillen Sacoto MJ, Gauthier J, Hamdan FF, Laberge AM, Campeau PM, Louie RJ, Cathey SS, Prinz I, Jorge AAL, Terhal PA, Lenhard B, Wieczorek D, Strom TM, Agrawal PB, Britsch S, Tolosa E, Kubisch C.

Brain. 2018 Aug 1;141(8):2299-2311. doi: 10.1093/brain/awy173.


Corrigendum: Incorrect Spelling of Author's Name: US Preventive Services Task Force prostate-specific antigen screening guidelines result in higher Gleason score diagnoses.

Gejerman G, Ciccone P, Goldstein M, Lanteri V, Schlecker B, Sanzone J, Esposito M, Rome S, Ciccone M, Margolis E, Simon R, Guo Y, Pentakota SR, Sadeghi-Nejad H.

Investig Clin Urol. 2018 Jul;59(4):283. doi: 10.4111/icu.2018.59.4.283. Epub 2018 Jun 29.


"Enhanced Recovery" Protocol Compliance Influences Length of Stay: Resolving Barriers to Implementation.

Zoog E, Simon R, Stanley JD, Moore R, Lorenzo-Rivero S, Shepherd B, Gao C, Nelson E.

Am Surg. 2018 Jun 1;84(6):801-807.


Myocarditis in Giant Cell Arteritis Diagnosed With Fluorine 18-Labeled Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography: Case Report and Review of the Literature.

Simon R, Perel-Winkler A, Bokhari S, Fazlollahi L, Nickerson K.

J Clin Rheumatol. 2018 Jun 21. doi: 10.1097/RHU.0000000000000796. [Epub ahead of print] No abstract available.


Deletions in guaBA and htrA but not clpX or rfaL constitute a live-attenuated vaccine strain of Salmonella Newport to protect against serogroup C2-C3 Salmonella in mice.

Fuche FJ, Jones JA, Ramachandran G, Higginson EE, Simon R, Tennant SM.

Hum Vaccin Immunother. 2018 Jun 21:1-9. doi: 10.1080/21645515.2018.1491499. [Epub ahead of print]


13q deletion is linked to an adverse phenotype and poor prognosis in prostate cancer.

Kluth M, Scherzai S, Büschek F, Fraune C, Möller K, Höflmayer D, Minner S, Göbel C, Möller-Koop C, Hinsch A, Neubauer E, Tsourlakis MC, Sauter G, Heinzer H, Graefen M, Wilczak W, Luebke AM, Burandt E, Steurer S, Schlomm T, Simon R.

Genes Chromosomes Cancer. 2018 Oct;57(10):504-512. doi: 10.1002/gcc.22645. Epub 2018 Aug 20.


Systematic review and meta-analysis of controlled intervention studies on the effectiveness of long-chain omega-3 fatty acids in patients with nonalcoholic fatty liver disease.

Musa-Veloso K, Venditti C, Lee HY, Darch M, Floyd S, West S, Simon R.

Nutr Rev. 2018 Aug 1;76(8):581-602. doi: 10.1093/nutrit/nuy022.


Marked Prognostic Impact of Minimal Lymphatic Tumor Spread in Prostate Cancer.

Wilczak W, Wittmer C, Clauditz T, Minner S, Steurer S, Büscheck F, Krech T, Lennartz M, Harms L, Leleu D, Ahrens M, Ingwerth S, Günther CT, Koop C, Simon R, Jacobsen F, Tsourlakis MC, Chirico V, Höflmayer D, Vettorazzi E, Haese A, Steuber T, Salomon G, Michl U, Budäus L, Tilki D, Thederan I, Fraune C, Göbel C, Henrich MC, Juhnke M, Möller K, Bawahab AA, Uhlig R, Adam M, Weidemann S, Beyer B, Huland H, Graefen M, Sauter G, Schlomm T.

Eur Urol. 2018 Sep;74(3):376-386. doi: 10.1016/j.eururo.2018.05.034. Epub 2018 Jun 13.


Elemental changes of hippocampal formation occurring during postnatal brain development.

Chwiej J, Palczynska M, Skoczen A, Janeczko K, Cieslak J, Simon R, Setkowicz Z.

J Trace Elem Med Biol. 2018 Sep;49:1-7. doi: 10.1016/j.jtemb.2018.04.030. Epub 2018 Apr 25.


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