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Items: 1 to 50 of 86

1.

Vasoactive hormone adrenomedullin and its binding protein: anti-inflammatory effects by up-regulating peroxisome proliferator-activated receptor-gamma.

Miksa M, Wu R, Cui X, Dong W, Das P, Simms HH, Ravikumar TS, Wang P.

J Immunol. 2007 Nov 1;179(9):6263-72.

2.

Ghrelin down-regulates proinflammatory cytokines in sepsis through activation of the vagus nerve.

Wu R, Dong W, Cui X, Zhou M, Simms HH, Ravikumar TS, Wang P.

Ann Surg. 2007 Mar;245(3):480-6.

3.

Adrenomedullin and adrenomedullin-binding protein-1 downregulate inflammatory cytokines and attenuate tissue injury after gut ischemia-reperfusion.

Carrizo GJ, Wu R, Cui X, Dwivedi AJ, Simms HH, Wang P.

Surgery. 2007 Feb;141(2):245-53. Epub 2006 Sep 14.

PMID:
17263982
4.

Adrenomedullin and adrenomedullin binding protein-1 prevent metabolic acidosis after uncontrolled hemorrhage in rats.

Wu R, Dong W, Zhou M, Simms HH, Marini CP, Ravikumar TS, Wang P.

Crit Care Med. 2007 Mar;35(3):912-8.

PMID:
17255858
5.

Suppression of hepatocyte CYP1A2 expression by Kupffer cells via AhR pathway: the central role of proinflammatory cytokines.

Wu R, Cui X, Dong W, Zhou M, Simms HH, Wang P.

Int J Mol Med. 2006 Aug;18(2):339-46.

PMID:
16820944
6.

The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-gamma.

Siddiqui AM, Cui X, Wu R, Dong W, Zhou M, Hu M, Simms HH, Wang P.

Crit Care Med. 2006 Jul;34(7):1874-82.

PMID:
16715036
7.

Proapoptotic effect of curcumin on human neutrophils: activation of the p38 mitogen-activated protein kinase pathway.

Hu M, Du Q, Vancurova I, Lin X, Miller EJ, Simms HH, Wang P.

Crit Care Med. 2005 Nov;33(11):2571-8.

PMID:
16276182
9.

Divergent roles of murine neutrophil chemokines in hemorrhage induced priming for acute lung injury.

Lomas-Neira J, Chung CS, Grutkoski PS, Dunican A, Simms HH, Cioffi WG, Ayala A.

Cytokine. 2005 Aug 7;31(3):169-79.

PMID:
15961314
10.

Gut-derived norepinephrine plays an important role in up-regulating IL-1beta and IL-10.

Zhou M, Das P, Simms HH, Wang P.

Biochim Biophys Acta. 2005 Jun 10;1740(3):446-52. Epub 2004 Nov 19.

11.

Adrenomedullin and its binding protein attenuate the proinflammatory response after hemorrhage.

Cui X, Wu R, Zhou M, Dong W, Ulloa L, Yang H, Wang H, Tracey KJ, Simms HH, Wang P.

Crit Care Med. 2005 Feb;33(2):391-8.

PMID:
15699844
12.
13.

NF-kappaB protects lung epithelium against hyperoxia-induced nonapoptotic cell death-oncosis.

Franek WR, Morrow DM, Zhu H, Vancurova I, Miskolci V, Darley-Usmar K, Simms HH, Mantell LL.

Free Radic Biol Med. 2004 Nov 15;37(10):1670-9.

PMID:
15477018
14.

Regulation of polymorphonuclear leukocyte apoptosis: role of lung endothelium-epithelium bilayer transmigration.

Hu M, Lin X, Du Q, Miller EJ, Wang P, Simms HH.

Am J Physiol Lung Cell Mol Physiol. 2005 Feb;288(2):L266-74. Epub 2004 Oct 8.

15.

Delayed administration of human inter-alpha inhibitor proteins reduces mortality in sepsis.

Wu R, Cui X, Lim YP, Bendelja K, Zhou M, Simms HH, Wang P.

Crit Care Med. 2004 Aug;32(8):1747-52.

PMID:
15286553
16.
17.

Differential expression of cytochrome P450 isoforms in the lungs of septic animals.

Cui X, Wu R, Zhou M, Simms HH, Wang P.

Crit Care Med. 2004 May;32(5):1186-91.

PMID:
15190971
18.

Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis.

Wu R, Zhou M, Cui X, Simms HH, Wang P.

Am J Physiol Heart Circ Physiol. 2004 Sep;287(3):H1296-302. Epub 2004 May 20.

19.

Down-regulation of hepatic CYP1A2 plays an important role in inflammatory responses in sepsis.

Crawford JH, Yang S, Zhou M, Simms HH, Wang P.

Crit Care Med. 2004 Feb;32(2):502-8.

PMID:
14758170
20.

Standardizing vascular surgery residency: merger of two programs to create one model.

Friedman SG, Greben C, Scher LA, Safa T, Faust G, Halpern V, Simms HH.

Vasc Endovascular Surg. 2004 Jan-Feb;38(1):63-7.

PMID:
14760479
21.

Transmigration across a lung epithelial monolayer delays apoptosis of polymorphonuclear leukocytes.

Hu M, Miller EJ, Lin X, Simms HH.

Surgery. 2004 Jan;135(1):87-98.

PMID:
14694305
22.

Ghrelin clearance is reduced at the late stage of polymicrobial sepsis.

Wu R, Zhou M, Cui X, Simms HH, Wang P.

Int J Mol Med. 2003 Nov;12(5):777-81.

PMID:
14533009
23.

Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity.

Chung CS, Song GY, Lomas J, Simms HH, Chaudry IH, Ayala A.

J Leukoc Biol. 2003 Sep;74(3):344-51.

PMID:
12949237
24.

Alpha-defensin 1 (human neutrophil protein 1) as an antichemotactic agent for human polymorphonuclear leukocytes.

Grutkoski PS, Graeber CT, Lim YP, Ayala A, Simms HH.

Antimicrob Agents Chemother. 2003 Aug;47(8):2666-8.

25.

Abdominal compartment syndrome: clinical manifestations and predictive factors.

McNelis J, Marini CP, Simms HH.

Curr Opin Crit Care. 2003 Apr;9(2):133-6. Review.

PMID:
12657976
26.

Adrenomedullin and adrenomedullin binding protein-1: their role in the septic response.

Fowler DE, Yang S, Zhou M, Chaudry IH, Simms HH, Wang P.

J Surg Res. 2003 Feb;109(2):175-81. Review.

PMID:
12643861
27.

Abdominal compartment syndrome in the surgical intensive care unit.

Mcnelis J, Soffer S, Marini CP, Jurkiewicz A, Ritter G, Simms HH, Nathan I.

Am Surg. 2002 Jan;68(1):18-23.

PMID:
12467311
28.

Shock-induced neutrophil mediated priming for acute lung injury in mice: divergent effects of TLR-4 and TLR-4/FasL deficiency.

Ayala A, Chung CS, Lomas JL, Song GY, Doughty LA, Gregory SH, Cioffi WG, LeBlanc BW, Reichner J, Simms HH, Grutkoski PS.

Am J Pathol. 2002 Dec;161(6):2283-94.

30.

Role of primary breast cancer characteristics in predicting positive sentinel lymph node biopsy results: a multivariate analysis.

Chen M, Palleschi S, Khoynezhad A, Gecelter G, Marini CP, Simms HH.

Arch Surg. 2002 May;137(5):606-9; discussion 609-10.

PMID:
11982477
31.

Predictive factors associated with the development of abdominal compartment syndrome in the surgical intensive care unit.

McNelis J, Marini CP, Jurkiewicz A, Fields S, Caplin D, Stein D, Ritter G, Nathan I, Simms HH.

Arch Surg. 2002 Feb;137(2):133-6.

PMID:
11822945
32.
33.

Diagnosis of acute cholecystitis: sensitivity of sonography, cholescintigraphy, and combined sonography-cholescintigraphy.

Kalimi R, Gecelter GR, Caplin D, Brickman M, Tronco GT, Love C, Yao J, Simms HH, Marini CP.

J Am Coll Surg. 2001 Dec;193(6):609-13.

PMID:
11768676
34.

Prolonged lactate clearance is associated with increased mortality in the surgical intensive care unit.

McNelis J, Marini CP, Jurkiewicz A, Szomstein S, Simms HH, Ritter G, Nathan IM.

Am J Surg. 2001 Nov;182(5):481-5.

PMID:
11754855
35.

Inhibition of Fas signaling prevents hepatic injury and improves organ blood flow during sepsis.

Chung CS, Yang S, Song GY, Lomas J, Wang P, Simms HH, Chaudry IH, Ayala A.

Surgery. 2001 Aug;130(2):339-45.

PMID:
11490369
36.

A 9-year, single-institution, retrospective review of death rate and prognostic factors in adult respiratory distress syndrome.

Rocco TR Jr, Reinert SE, Cioffi W, Harrington D, Buczko G, Simms HH.

Ann Surg. 2001 Mar;233(3):414-22.

37.

TNFalpha-induced suppression of PMN apoptosis is mediated through interleukin-8 production.

Dunican AL, Leuenroth SJ, Grutkoski P, Ayala A, Simms HH.

Shock. 2000 Sep;14(3):284-8; discussion 288-9.

PMID:
11028544
38.

Inadequate proof of adverse outcome due to the use of fluconazole in critically ill patients

Rocco TR, Simms HH.

Arch Surg. 2000 Sep;135(9):1114. No abstract available.

PMID:
10982522
39.

Suppression of PMN apoptosis by hypoxia is dependent on Mcl-1 and MAPK activity.

Leuenroth SJ, Grutkoski PS, Ayala A, Simms HH.

Surgery. 2000 Aug;128(2):171-7.

PMID:
10922988
40.

The loss of Mcl-1 expression in human polymorphonuclear leukocytes promotes apoptosis.

Leuenroth SJ, Grutkoski PS, Ayala A, Simms HH.

J Leukoc Biol. 2000 Jul;68(1):158-66.

PMID:
10914504
41.

Neutrophils regulate their own apoptosis via preservation of CXC receptors.

Dunican A, Grutkoski P, Leuenroth S, Ayala A, Simms HH.

J Surg Res. 2000 May 1;90(1):32-8.

PMID:
10781372
42.
43.
44.

IL-1beta stimulation induces paracrine regulation of PMN function and apoptosis.

Grutkoski PS, D'Amico R, Ayala A, Simms HH.

Shock. 1999 Nov;12(5):373-81.

PMID:
10565612
45.

Role of granulocyte-macrophage colony-stimulating factor and its receptor in the genesis of acute respiratory distress syndrome through an effect on neutrophil apoptosis.

Goodman ER, Stricker P, Velavicius M, Fonseca R, Kleinstein E, Lavery R, Deitch EA, Hauser CJ, Simms HH.

Arch Surg. 1999 Oct;134(10):1049-54.

PMID:
10522844
46.
47.

Regulation of IL-8RA (CXCR1) expression in polymorphonuclear leukocytes by hypoxia/reoxygenation.

Grutkoski PS, Graeber CT, D'Amico R, Keeping H, Simms HH.

J Leukoc Biol. 1999 Feb;65(2):171-8.

PMID:
10088599
48.

Analysis of the effect of conversion from open to closed surgical intensive care unit.

Ghorra S, Reinert SE, Cioffi W, Buczko G, Simms HH.

Ann Surg. 1999 Feb;229(2):163-71.

49.
50.

The role of neutrophil-derived oxidants as second messengers in interleukin 1beta-stimulated cells.

Derevianko A, Graeber T, D'Amico R, Simms HH.

Shock. 1998 Jul;10(1):54-61.

PMID:
9688092

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