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Items: 19

1.

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.

Calabrese DR, Chen X, Leon EC, Gaikwad SM, Phyo Z, Hewitt WM, Alden S, Hilimire TA, He F, Michalowski AM, Simmons JK, Saunders LB, Zhang S, Connors D, Walters KJ, Mock BA, Schneekloth JS Jr.

Nat Commun. 2018 Oct 12;9(1):4229. doi: 10.1038/s41467-018-06315-w.

2.

Targeted delivery of cytotoxic NAMPT inhibitors using antibody-drug conjugates.

Neumann CS, Olivas KC, Anderson ME, Cochran JH, Jin S, Li F, Loftus LV, Meyer DW, Neale J, Nix JC, Pittman PG, Simmons JK, Ulrich ML, Waight AB, Wong A, Zaval MC, Zeng W, Lyon RP, Senter PD.

Mol Cancer Ther. 2018 Sep 21. pii: molcanther.0643.2018. doi: 10.1158/1535-7163.MCT-18-0643. [Epub ahead of print]

PMID:
30242091
3.

Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation.

Simmons JK, Michalowski AM, Gamache BJ, DuBois W, Patel J, Zhang K, Gary J, Zhang S, Gaikwad S, Connors D, Watson N, Leon E, Chen JQ, Kuehl WM, Lee MP, Zingone A, Landgren O, Ordentlich P, Huang J, Mock BA.

Mol Cancer Ther. 2017 Sep;16(9):2008-2021. doi: 10.1158/1535-7163.MCT-17-0171. Epub 2017 May 18.

4.

Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody-Drug Conjugates.

Burke PJ, Hamilton JZ, Jeffrey SC, Hunter JH, Doronina SO, Okeley NM, Miyamoto JB, Anderson ME, Stone IJ, Ulrich ML, Simmons JK, McKinney EE, Senter PD, Lyon RP.

Mol Cancer Ther. 2017 Jan;16(1):116-123. doi: 10.1158/1535-7163.MCT-16-0343. Epub 2016 Nov 9.

5.

Feline Mammary Cancer.

Hassan BB, Elshafae SM, Supsavhad W, Simmons JK, Dirksen WP, Sokkar SM, Rosol TJ.

Vet Pathol. 2017 Jan;54(1):32-43. doi: 10.1177/0300985816650243. Epub 2016 Jul 11.

PMID:
27281014
6.

Molecular Pathways: Increased Susceptibility to Infection Is a Complication of mTOR Inhibitor Use in Cancer Therapy.

Eiden AM, Zhang S, Gary JM, Simmons JK, Mock BA.

Clin Cancer Res. 2016 Jan 15;22(2):277-83. doi: 10.1158/1078-0432.CCR-14-3239. Epub 2015 Nov 25. Review.

7.

Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression.

Felsenstein KM, Saunders LB, Simmons JK, Leon E, Calabrese DR, Zhang S, Michalowski A, Gareiss P, Mock BA, Schneekloth JS Jr.

ACS Chem Biol. 2016 Jan 15;11(1):139-48. doi: 10.1021/acschembio.5b00577. Epub 2015 Nov 6.

8.

Animal Models of Bone Metastasis.

Simmons JK, Hildreth BE 3rd, Supsavhad W, Elshafae SM, Hassan BB, Dirksen WP, Toribio RE, Rosol TJ.

Vet Pathol. 2015 Sep;52(5):827-41. doi: 10.1177/0300985815586223. Epub 2015 May 28. Review.

9.

Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity.

Ou O, Huppi K, Chakka S, Gehlhaus K, Dubois W, Patel J, Chen J, Mackiewicz M, Jones TL, Pitt JJ, Martin SE, Goldsmith P, Simmons JK, Mock BA, Caplen NJ.

Cancer Lett. 2014 Nov 28;354(2):336-47. doi: 10.1016/j.canlet.2014.08.043. Epub 2014 Sep 1.

10.

Canine prostate cancer cell line (Probasco) produces osteoblastic metastases in vivo.

Simmons JK, Dirksen WP, Hildreth BE 3rd, Dorr C, Williams C, Thomas R, Breen M, Toribio RE, Rosol TJ.

Prostate. 2014 Sep;74(13):1251-65. doi: 10.1002/pros.22838. Epub 2014 Jul 7.

11.

Biochemical characterization of prostate-specific membrane antigen from canine prostate carcinoma cells.

Wu LY, Johnson JM, Simmons JK, Mendes DE, Geruntho JJ, Liu T, Dirksen WP, Rosol TJ, Davis WC, Berkman CE.

Prostate. 2014 May;74(5):451-7. doi: 10.1002/pros.22727. Epub 2014 Jan 21.

12.

TORC1 and class I HDAC inhibitors synergize to suppress mature B cell neoplasms.

Simmons JK, Patel J, Michalowski A, Zhang S, Wei BR, Sullivan P, Gamache B, Felsenstein K, Kuehl WM, Simpson RM, Zingone A, Landgren O, Mock BA.

Mol Oncol. 2014 Mar;8(2):261-72. doi: 10.1016/j.molonc.2013.11.007. Epub 2013 Dec 3.

13.

Combined zoledronic acid and meloxicam reduced bone loss and tumour growth in an orthotopic mouse model of bone-invasive oral squamous cell carcinoma.

Martin CK, Dirksen WP, Carlton MM, Lanigan LG, Pillai SP, Werbeck JL, Simmons JK, Hildreth BE 3rd, London CA, Toribio RE, Rosol TJ.

Vet Comp Oncol. 2015 Sep;13(3):203-17. doi: 10.1111/vco.12037. Epub 2013 May 8.

14.

Mouse genetics 2011: meeting report.

Simmons JK, Amlin-Van Schaick JC, Geiger TR, Reilly K, Hunter K, Mock BA.

Mamm Genome. 2012 Apr;23(3-4):225-31. doi: 10.1007/s00335-012-9390-6. Epub 2012 Feb 23. No abstract available.

PMID:
22358507
15.

A novel spongiform leukoencephalomyelopathy in Border Terrier puppies.

Martin-Vaquero P, da Costa RC, Simmons JK, Beamer GL, J├Ąderlund KH, Oglesbee MJ.

J Vet Intern Med. 2012 Mar-Apr;26(2):402-6. doi: 10.1111/j.1939-1676.2011.00873.x. Epub 2012 Jan 23. No abstract available.

16.

Development of a brain metastatic canine prostate cancer cell line.

Thudi NK, Shu ST, Martin CK, Lanigan LG, Nadella MV, Van Bokhoven A, Werbeck JL, Simmons JK, Murahari S, Kisseberth WC, Breen M, Williams C, Chen CS, McCauley LK, Keller ET, Rosol TJ.

Prostate. 2011 Sep;71(12):1251-63. doi: 10.1002/pros.21341. Epub 2011 Feb 14.

17.

Loss of tumor progression locus 2 (tpl2) enhances tumorigenesis and inflammation in two-stage skin carcinogenesis.

Decicco-Skinner KL, Trovato EL, Simmons JK, Lepage PK, Wiest JS.

Oncogene. 2011 Jan 27;30(4):389-97. doi: 10.1038/onc.2010.447. Epub 2010 Oct 11.

18.

Pathology in practice. Necrotizing pyogranulomatous meningoencephalitis with intralesional fungal hyphae, consistent with Cladophialophora bantiana.

Simmons JK, McManamon R, Rech RR, Phillips AE, Howerth EW.

J Am Vet Med Assoc. 2010 Feb 1;236(3):295-7. doi: 10.2460/javma.236.3.295. No abstract available.

PMID:
20113240
19.

Differences between proton- and pi --induced production of the charmonium chi states.

Bauer DA, Graff TL, Lukens PT, Wilson JR, Alverson GO, Ascoli G, Barnes VE, Bellinger JN, Cihangir S, Cooper JW, Davis C, Garfinkel AF, Holloway LE, Karliner I I, Kirk TB, Koester LJ, Laasanen AT, Li W, Oliver WP, Pordes SH, Sard RD, Simmons JK, Thornton RK, Wehmann AA.

Phys Rev Lett. 1985 Feb 25;54(8):753-756. No abstract available.

PMID:
10031607

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