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Items: 1 to 50 of 104

1.

Impact of Ferumoxytol Magnetic Resonance Imaging on the Rhesus Macaque Maternal-Fetal Interface.

Nguyen SM, Wiepz GJ, Schotzko M, Simmons HA, Mejia A, Ludwig KD, Zhu A, Brunner K, Hernando D, Reeder SB, Wieben O, Johnson K, Shah D, Golos TG.

Biol Reprod. 2019 Sep 12. pii: ioz181. doi: 10.1093/biolre/ioz181. [Epub ahead of print]

PMID:
31511859
2.

Risk of Zika microcephaly correlates with features of maternal antibodies.

Robbiani DF, Olsen PC, Costa F, Wang Q, Oliveira TY, Nery N Jr, Aromolaran A, do Rosário MS, Sacramento GA, Cruz JS, Khouri R, Wunder EA Jr, Mattos A, de Paula Freitas B, Sarno M, Archanjo G, Daltro D, Carvalho GBS, Pimentel K, de Siqueira IC, de Almeida JRM, Henriques DF, Lima JA, Vasconcelos PFC, Schaefer-Babajew D, Azzopardi SA, Bozzacco L, Gazumyan A, Belfort R Jr, Alcântara AP, Carvalho G, Moreira L, Araujo K, Reis MG, Keesler RI, Coffey LL, Tisoncik-Go J, Gale M Jr, Rajagopal L, Adams Waldorf KM, Dudley DM, Simmons HA, Mejia A, O'Connor DH, Steinbach RJ, Haese N, Smith J, Lewis A, Colgin L, Roberts V, Frias A, Kelleher M, Hirsch A, Streblow DN, Rice CM, MacDonald MR, de Almeida ARP, Van Rompay KKA, Ko AI, Nussenzweig MC.

J Exp Med. 2019 Aug 14. pii: jem.20191061. doi: 10.1084/jem.20191061. [Epub ahead of print]

PMID:
31413072
3.

Colonic inflammation affects myenteric alpha-synuclein in nonhuman primates.

Resnikoff H, Metzger JM, Lopez M, Bondarenko V, Mejia A, Simmons HA, Emborg ME.

J Inflamm Res. 2019 May 7;12:113-126. doi: 10.2147/JIR.S196552. eCollection 2019.

4.

Zika viruses of African and Asian lineages cause fetal harm in a mouse model of vertical transmission.

Jaeger AS, Murrieta RA, Goren LR, Crooks CM, Moriarty RV, Weiler AM, Rybarczyk S, Semler MR, Huffman C, Mejia A, Simmons HA, Fritsch M, Osorio JE, Eickhoff JC, O'Connor SL, Ebel GD, Friedrich TC, Aliota MT.

PLoS Negl Trop Dis. 2019 Apr 17;13(4):e0007343. doi: 10.1371/journal.pntd.0007343. eCollection 2019 Apr.

5.

Neutrophil progenitor populations of rhesus macaques.

Weisgrau KL, Vosler LJ, Pomplun NL, Hayes JM, Simmons HA, Friedrichs KR, Rakasz EG.

J Leukoc Biol. 2019 Jan;105(1):113-121. doi: 10.1002/JLB.1TA1117-431RR. Epub 2018 Nov 5.

PMID:
30395351
6.

Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates.

Dudley DM, Van Rompay KK, Coffey LL, Ardeshir A, Keesler RI, Bliss-Moreau E, Grigsby PL, Steinbach RJ, Hirsch AJ, MacAllister RP, Pecoraro HL, Colgin LM, Hodge T, Streblow DN, Tardif S, Patterson JL, Tamhankar M, Seferovic M, Aagaard KM, Martín CS, Chiu CY, Panganiban AT, Veazey RS, Wang X, Maness NJ, Gilbert MH, Bohm RP, Adams Waldorf KM, Gale M Jr, Rajagopal L, Hotchkiss CE, Mohr EL, Capuano SV 3rd, Simmons HA, Mejia A, Friedrich TC, Golos TG, O'Connor DH.

Nat Med. 2018 Aug;24(8):1104-1107. doi: 10.1038/s41591-018-0088-5. Epub 2018 Jul 2.

7.

Molecularly barcoded Zika virus libraries to probe in vivo evolutionary dynamics.

Aliota MT, Dudley DM, Newman CM, Weger-Lucarelli J, Stewart LM, Koenig MR, Breitbach ME, Weiler AM, Semler MR, Barry GL, Zarbock KR, Haj AK, Moriarty RV, Mohns MS, Mohr EL, Venturi V, Schultz-Darken N, Peterson E, Newton W, Schotzko ML, Simmons HA, Mejia A, Hayes JM, Capuano S 3rd, Davenport MP, Friedrich TC, Ebel GD, O'Connor SL, O'Connor DH.

PLoS Pathog. 2018 Mar 28;14(3):e1006964. doi: 10.1371/journal.ppat.1006964. eCollection 2018 Mar.

8.

Model of Traumatic Spinal Cord Injury for Evaluating Pharmacologic Treatments in Cynomolgus Macaques (Macaca fasicularis).

Seth N, Simmons HA, Masood F, Graham WA, Rosene DL, Westmoreland SV, Cummings SM, Gwardjan B, Sejdic E, Hoggatt AF, Schalk DR, Abdullah HA, Sledge JB, Nesathurai S.

Comp Med. 2018 Feb 1;68(1):63-73.

9.

Ocular and uteroplacental pathology in a macaque pregnancy with congenital Zika virus infection.

Mohr EL, Block LN, Newman CM, Stewart LM, Koenig M, Semler M, Breitbach ME, Teixeira LBC, Zeng X, Weiler AM, Barry GL, Thoong TH, Wiepz GJ, Dudley DM, Simmons HA, Mejia A, Morgan TK, Salamat MS, Kohn S, Antony KM, Aliota MT, Mohns MS, Hayes JM, Schultz-Darken N, Schotzko ML, Peterson E, Capuano S 3rd, Osorio JE, O'Connor SL, Friedrich TC, O'Connor DH, Golos TG.

PLoS One. 2018 Jan 30;13(1):e0190617. doi: 10.1371/journal.pone.0190617. eCollection 2018.

10.

Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infection.

Bailey AL, Buechler CR, Matson DR, Peterson EJ, Brunner KG, Mohns MS, Breitbach M, Stewart LM, Ericsen AJ, Newman CM, Koenig MR, Mohr E, Tan J, Capuano S 3rd, Simmons HA, Yang DT, O'Connor DH.

PLoS Pathog. 2017 Oct 26;13(10):e1006692. doi: 10.1371/journal.ppat.1006692. eCollection 2017 Oct.

11.

Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques.

Nguyen SM, Antony KM, Dudley DM, Kohn S, Simmons HA, Wolfe B, Salamat MS, Teixeira LBC, Wiepz GJ, Thoong TH, Aliota MT, Weiler AM, Barry GL, Weisgrau KL, Vosler LJ, Mohns MS, Breitbach ME, Stewart LM, Rasheed MN, Newman CM, Graham ME, Wieben OE, Turski PA, Johnson KM, Post J, Hayes JM, Schultz-Darken N, Schotzko ML, Eudailey JA, Permar SR, Rakasz EG, Mohr EL, Capuano S 3rd, Tarantal AF, Osorio JE, O'Connor SL, Friedrich TC, O'Connor DH, Golos TG.

PLoS Pathog. 2017 May 25;13(5):e1006378. doi: 10.1371/journal.ppat.1006378. eCollection 2017 May.

12.

Acute Fetal Demise with First Trimester Maternal Infection Resulting from Listeria monocytogenes in a Nonhuman Primate Model.

Wolfe B, Wiepz GJ, Schotzko M, Bondarenko GI, Durning M, Simmons HA, Mejia A, Faith NG, Sampene E, Suresh M, Kathariou S, Czuprynski CJ, Golos TG.

MBio. 2017 Feb 21;8(1). pii: e01938-16. doi: 10.1128/mBio.01938-16.

13.

Evidence of scrapie transmission to sheep via goat milk.

Konold T, Thorne L, Simmons HA, Hawkins SA, Simmons MM, González L.

BMC Vet Res. 2016 Sep 17;12:208. doi: 10.1186/s12917-016-0807-4.

14.

A rhesus macaque model of Asian-lineage Zika virus infection.

Dudley DM, Aliota MT, Mohr EL, Weiler AM, Lehrer-Brey G, Weisgrau KL, Mohns MS, Breitbach ME, Rasheed MN, Newman CM, Gellerup DD, Moncla LH, Post J, Schultz-Darken N, Schotzko ML, Hayes JM, Eudailey JA, Moody MA, Permar SR, O'Connor SL, Rakasz EG, Simmons HA, Capuano S, Golos TG, Osorio JE, Friedrich TC, O'Connor DH.

Nat Commun. 2016 Jun 28;7:12204. doi: 10.1038/ncomms12204.

15.

Estimation of Shear Wave Speed in the Rhesus Macaques' Uterine Cervix.

Huang B, Drehfal LC, Rosado-Mendez IM, Guerrero QW, Palmeri ML, Simmons HA, Feltovich H, Hall TJ.

IEEE Trans Ultrason Ferroelectr Freq Control. 2016 Sep;63(9):1243-52. doi: 10.1109/TUFFC.2016.2524259. Epub 2016 Feb 8.

16.

Age-Associated Pathology in Rhesus Macaques (Macaca mulatta).

Simmons HA.

Vet Pathol. 2016 Mar;53(2):399-416. doi: 10.1177/0300985815620628. Epub 2016 Feb 10. Review.

17.

Objects in Contact with Classical Scrapie Sheep Act as a Reservoir for Scrapie Transmission.

Konold T, Hawkins SA, Thurston LC, Maddison BC, Gough KC, Duarte A, Simmons HA.

Front Vet Sci. 2015 Sep 14;2:32. doi: 10.3389/fvets.2015.00032. eCollection 2015.

18.

Durable sequence stability and bone marrow tropism in a macaque model of human pegivirus infection.

Bailey AL, Lauck M, Mohns M, Peterson EJ, Beheler K, Brunner KG, Crosno K, Mejia A, Mutschler J, Gehrke M, Greene J, Ericsen AJ, Weiler A, Lehrer-Brey G, Friedrich TC, Sibley SD, Kallas EG, Capuano S 3rd, Rogers J, Goldberg TL, Simmons HA, O'Connor DH.

Sci Transl Med. 2015 Sep 16;7(305):305ra144. doi: 10.1126/scitranslmed.aab3467.

19.

Circulation of prions within dust on a scrapie affected farm.

Gough KC, Baker CA, Simmons HA, Hawkins SA, Maddison BC.

Vet Res. 2015 Apr 16;46:40. doi: 10.1186/s13567-015-0176-1.

20.

Persistence of ovine scrapie infectivity in a farm environment following cleaning and decontamination.

Hawkins SA, Simmons HA, Gough KC, Maddison BC.

Vet Rec. 2015 Jan 24;176(4):99. doi: 10.1136/vr.102743. Epub 2014 Oct 31.

PMID:
25362003
21.

Evidence of effective scrapie transmission via colostrum and milk in sheep.

Konold T, Moore SJ, Bellworthy SJ, Terry LA, Thorne L, Ramsay A, Salguero FJ, Simmons MM, Simmons HA.

BMC Vet Res. 2013 May 7;9:99. doi: 10.1186/1746-6148-9-99.

22.

Transmission of classical scrapie via goat milk.

Konold T, Simmons HA, Webb PR, Bellerby PJ, Hawkins SA, González L.

Vet Rec. 2013 Apr 27;172(17):455. doi: 10.1136/vr.f2613. No abstract available.

PMID:
23625249
23.

Meeting report: Spontaneous lesions and diseases in wild, captive-bred, and zoo-housed nonhuman primates and in nonhuman primate species used in drug safety studies.

Sasseville VG, Mansfield KG, Mankowski JL, Tremblay C, Terio KA, Mätz-Rensing K, Gruber-Dujardin E, Delaney MA, Schmidt LD, Liu D, Markovits JE, Owston M, Harbison C, Shanmukhappa S, Miller AD, Kaliyaperumal S, Assaf BT, Kattenhorn L, Macri SC, Simmons HA, Baldessari A, Sharma P, Courtney C, Bradley A, Cline JM, Reindel JF, Hutto DL, Montali RJ, Lowenstine LJ.

Vet Pathol. 2012 Nov;49(6):1057-69. doi: 10.1177/0300985812461655.

24.

A monoclonal antibody-GDNF fusion protein is not neuroprotective and is associated with proliferative pancreatic lesions in parkinsonian monkeys.

Ohshima-Hosoyama S, Simmons HA, Goecks N, Joers V, Swanson CR, Bondarenko V, Velotta R, Brunner K, Wood LD, Hruban RH, Emborg ME.

PLoS One. 2012;7(6):e39036. doi: 10.1371/journal.pone.0039036. Epub 2012 Jun 20.

25.

Vaccination with cancer- and HIV infection-associated endogenous retrotransposable elements is safe and immunogenic.

Sacha JB, Kim IJ, Chen L, Ullah JH, Goodwin DA, Simmons HA, Schenkman DI, von Pelchrzim F, Gifford RJ, Nimityongskul FA, Newman LP, Wildeboer S, Lappin PB, Hammond D, Castrovinci P, Piaskowski SM, Reed JS, Beheler KA, Tharmanathan T, Zhang N, Muscat-King S, Rieger M, Fernandes C, Rumpel K, Gardner JP 2nd, Gebhard DH, Janies J, Shoieb A, Pierce BG, Trajkovic D, Rakasz E, Rong S, McCluskie M, Christy C, Merson JR, Jones RB, Nixon DF, Ostrowski MA, Loudon PT, Pruimboom-Brees IM, Sheppard NC.

J Immunol. 2012 Aug 1;189(3):1467-79. doi: 10.4049/jimmunol.1200079. Epub 2012 Jun 27.

26.

Characterization in vitro and in vivo of pandemic (H1N1) 2009 influenza viruses isolated from patients.

Watanabe T, Imai M, Watanabe S, Shinya K, Hatta M, Li C, Neumann G, Ozawa M, Hanson A, Zhong G, Fukuyama S, Kawakami E, Simmons HA, Schenkman D, Brunner K, Capuano SV 3rd, Weinfurter JT, Kilander A, Dudman SG, Suresh M, Hungnes O, Friedrich TC, Kawaoka Y.

J Virol. 2012 Sep;86(17):9361-8. doi: 10.1128/JVI.01214-12. Epub 2012 Jun 20.

27.

Avian-type receptor-binding ability can increase influenza virus pathogenicity in macaques.

Watanabe T, Shinya K, Watanabe S, Imai M, Hatta M, Li C, Wolter BF, Neumann G, Hanson A, Ozawa M, Yamada S, Imai H, Sakabe S, Takano R, Iwatsuki-Horimoto K, Kiso M, Ito M, Fukuyama S, Kawakami E, Gorai T, Simmons HA, Schenkman D, Brunner K, Capuano SV 3rd, Weinfurter JT, Nishio W, Maniwa Y, Igarashi T, Makino A, Travanty EA, Wang J, Kilander A, Dudman SG, Suresh M, Mason RJ, Hungnes O, Friedrich TC, Kawaoka Y.

J Virol. 2011 Dec;85(24):13195-203. doi: 10.1128/JVI.00859-11. Epub 2011 Sep 21.

28.

The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys.

Swanson CR, Joers V, Bondarenko V, Brunner K, Simmons HA, Ziegler TE, Kemnitz JW, Johnson JA, Emborg ME.

J Neuroinflammation. 2011 Aug 5;8:91. doi: 10.1186/1742-2094-8-91.

29.

The incidence of spontaneous neoplasia in two populations of captive rhesus macaques (Macaca mulatta).

Simmons HA, Mattison JA.

Antioxid Redox Signal. 2011 Jan 15;14(2):221-7. doi: 10.1089/ars.2010.3311. Epub 2010 Oct 28.

30.

'High-risk' pregnancy after perinatal loss: understanding the label.

Simmons HA, Goldberg LS.

Midwifery. 2011 Aug;27(4):452-7. doi: 10.1016/j.midw.2010.02.013. Epub 2010 Apr 22.

PMID:
20416998
31.

The evaluation of exposure risks for natural transmission of scrapie within an infected flock.

Dexter G, Tongue SC, Heasman L, Bellworthy SJ, Davis A, Moore SJ, Simmons MM, Sayers AR, Simmons HA, Matthews D.

BMC Vet Res. 2009 Oct 9;5:38. doi: 10.1186/1746-6148-5-38.

32.

Caloric restriction delays disease onset and mortality in rhesus monkeys.

Colman RJ, Anderson RM, Johnson SC, Kastman EK, Kosmatka KJ, Beasley TM, Allison DB, Cruzen C, Simmons HA, Kemnitz JW, Weindruch R.

Science. 2009 Jul 10;325(5937):201-4. doi: 10.1126/science.1173635.

33.

The discovery of novel calcium sensing receptor negative allosteric modulators.

Balan G, Bauman J, Bhattacharya S, Castrodad M, Healy DR, Herr M, Humphries P, Jennings S, Kalgutkar AS, Kapinos B, Khot V, Lazarra K, Li M, Li Y, Neagu C, Oliver R, Piotrowski DW, Price D, Qi H, Simmons HA, Southers J, Wei L, Zhang Y, Paralkar VM.

Bioorg Med Chem Lett. 2009 Jun 15;19(12):3328-32. doi: 10.1016/j.bmcl.2009.04.044. Epub 2009 Apr 18.

PMID:
19442519
34.

Atypical scrapie in sheep from a UK research flock which is free from classical scrapie.

Simmons HA, Simmons MM, Spencer YI, Chaplin MJ, Povey G, Davis A, Ortiz-Pelaez A, Hunter N, Matthews D, Wrathall AE.

BMC Vet Res. 2009 Feb 10;5:8. doi: 10.1186/1746-6148-5-8.

35.

Risks of transmitting ruminant spongiform encephalopathies (prion diseases) by semen and embryo transfer techniques.

Wrathall AE, Holyoak GR, Parsonson IM, Simmons HA.

Theriogenology. 2008 Sep 15;70(5):725-45. doi: 10.1016/j.theriogenology.2008.05.049. Epub 2008 Jun 30. Review.

PMID:
18586320
36.

Evidence of scrapie transmission via milk.

Konold T, Moore SJ, Bellworthy SJ, Simmons HA.

BMC Vet Res. 2008 Apr 8;4:14. doi: 10.1186/1746-6148-4-14.

37.

Experimental transmission of atypical scrapie to sheep.

Simmons MM, Konold T, Simmons HA, Spencer YI, Lockey R, Spiropoulos J, Everitt S, Clifford D.

BMC Vet Res. 2007 Aug 28;3:20.

38.

Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis.

Buckbinder L, Crawford DT, Qi H, Ke HZ, Olson LM, Long KR, Bonnette PC, Baumann AP, Hambor JE, Grasser WA 3rd, Pan LC, Owen TA, Luzzio MJ, Hulford CA, Gebhard DF, Paralkar VM, Simmons HA, Kath JC, Roberts WG, Smock SL, Guzman-Perez A, Brown TA, Li M.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10619-24. Epub 2007 May 30.

39.

Visceral and presumptive neural baylisascariasis in an orangutan (Pongo pygmaeus).

Hanley CS, Simmons HA, Wallace RS, Clyde VL.

J Zoo Wildl Med. 2006 Dec;37(4):553-7.

PMID:
17315445
40.

Erythema multiforme in a spotted hyena (Crocuta crocuta).

Hanley CS, Simmons HA, Wallace RS, Clyde VL.

J Zoo Wildl Med. 2005 Sep;36(3):515-9.

PMID:
17312775
41.

Multicentric t-cell lymphoma in a dromedary camel (Camelus dromedarius).

Simmons HA, Fitzgerald SD, Kiupel M, Rost DR, Emery RW.

J Zoo Wildl Med. 2005 Dec;36(4):727-9.

PMID:
17312737
42.

Lasofoxifene enhances vaginal mucus formation without causing hypertrophy and increases estrogen receptor beta and androgen receptor in rats.

Wang XN, Simmons HA, Salatto CT, Cosgrove PG, Thompson DD.

Menopause. 2006 Jul-Aug;13(4):609-20.

PMID:
16837883
43.

Surface-specific effects of a PPARgamma agonist, darglitazone, on bone in mice.

Li M, Pan LC, Simmons HA, Li Y, Healy DR, Robinson BS, Ke HZ, Brown TA.

Bone. 2006 Oct;39(4):796-806. Epub 2006 Jun 8.

PMID:
16759917
44.

A nonprostanoid EP4 receptor selective prostaglandin E2 agonist restores bone mass and strength in aged, ovariectomized rats.

Ke HZ, Crawford DT, Qi H, Simmons HA, Owen TA, Paralkar VM, Li M, Lu B, Grasser WA, Cameron KO, Lefker BA, DaSilva-Jardine P, Scott DO, Zhang Q, Tian XY, Jee WS, Brown TA, Thompson DD.

J Bone Miner Res. 2006 Apr;21(4):565-75. Epub 2006 Apr 5.

45.

A new vitamin D analog, 2MD, restores trabecular and cortical bone mass and strength in ovariectomized rats with established osteopenia.

Ke HZ, Qi H, Crawford DT, Simmons HA, Xu G, Li M, Plum L, Clagett-Dame M, DeLuca HF, Thompson DD, Brown TA.

J Bone Miner Res. 2005 Oct;20(10):1742-55. Epub 2005 Jun 13.

46.

Evaluation of risks of viral transmission to recipients of bovine embryos arising from fertilisation with virus-infected semen.

Wrathall AE, Simmons HA, Van Soom A.

Theriogenology. 2006 Jan 20;65(2):247-74. Epub 2005 Jul 7. Review.

PMID:
16005506
47.

Osteopenia and impaired fracture healing in aged EP4 receptor knockout mice.

Li M, Healy DR, Li Y, Simmons HA, Crawford DT, Ke HZ, Pan LC, Brown TA, Thompson DD.

Bone. 2005 Jul;37(1):46-54.

PMID:
15869929
48.

Long-term effects of aging and orchidectomy on bone and body composition in rapidly growing male rats.

Ke HZ, Crawford DT, Qi H, Chidsey-Frink KL, Simmons HA, Li M, Jee WS, Thompson DD.

J Musculoskelet Neuronal Interact. 2001 Mar;1(3):215-24.

49.

A comparison of the anabolic effects of rat and bovine parathyroid hormone (1-34) in ovariectomized rats.

Li M, Healy DR, Li Y, Simmons HA, Gao F, Ke HZ, Lu B, Owen TA, Thompson DD.

J Musculoskelet Neuronal Interact. 2001 Sep;2(1):77-83.

50.

The role of estrogen receptor-beta, in the early age-related bone gain and later age-related bone loss in female mice.

Ke HZ, Brown TA, Qi H, Crawford DT, Simmons HA, Petersen DN, Allen MR, McNeish JD, Thompson DD.

J Musculoskelet Neuronal Interact. 2002 Sep;2(5):479-88.

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