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Effect of Intensive and Standard Clinic-Based Hypertension Management on the Concordance Between Clinic and Ambulatory Blood Pressure and Blood Pressure Variability in SPRINT.

Ghazi L, Pajewski NM, Rifkin DE, Bates JT, Chang TI, Cushman WC, Glasser SP, Haley WE, Johnson KC, Kostis WJ, Papademetriou V, Rahman M, Simmons DL, Taylor A, Whelton PK, Wright JT, Bhatt UY, Drawz PE.

J Am Heart Assoc. 2019 Jul 16;8(14):e011706. doi: 10.1161/JAHA.118.011706. Epub 2019 Jul 15.


AAIM Guidelines for Interview and Post-Interview Communication for Graduate Medical Education Recruitment.

Alweis RL, Williams CM, Luther VP, Simmons DL, Kopelman R, Angus SV, Liao S, Nagalla S, Muchmore EA.

Am J Med. 2019 Sep;132(9):1106-1111. doi: 10.1016/j.amjmed.2019.05.023. Epub 2019 Jun 6. No abstract available.


Serum Sodium and Pulse Pressure in SPRINT.

Nowak KL, Chonchol M, Jovanovich A, You Z, Bates J, Foy C, Glasser S, Killeen AA, Kostis J, Rodriguez CJ, Segal M, Simmons DL, Taylor A, Lovato LC, Ambrosius WT, Supiano MA; SPRINT Research Group.

Am J Hypertens. 2019 Jun 11;32(7):649-656. doi: 10.1093/ajh/hpz055.


Parental Leave in Graduate Medical Education: Recommendations for Reform.

Vassallo P, Jeremiah J, Forman L, Dubois L, Simmons DL, Chretien K, Amin A, Coleman D, Collichio F.

Am J Med. 2019 Mar;132(3):385-389. doi: 10.1016/j.amjmed.2018.11.006. Epub 2018 Nov 30. No abstract available.


Antipyretic therapy: clinical pharmacology.

Lee JJ, Simmons DL.

Handb Clin Neurol. 2018;157:869-881. doi: 10.1016/B978-0-444-64074-1.00054-9. Review.


Long-Term Effects of Intensive Glycemic and Blood Pressure Control and Fenofibrate Use on Kidney Outcomes.

Mottl AK, Buse JB, Ismail-Beigi F, Sigal RJ, Pedley CF, Papademetriou V, Simmons DL, Katz L, Mychaleckyj JC, Craven TE.

Clin J Am Soc Nephrol. 2018 Nov 7;13(11):1693-1702. doi: 10.2215/CJN.06200518. Epub 2018 Oct 25.


Correction: High prevalence of elevated blood lead levels in both rural and urban Iowa newborns: Spatial patterns and area-level covariates.

Carrel M, Zahrieh D, Young SG, Oleson J, Ryckman KK, Wels B, Simmons DL, Saftlas A.

PLoS One. 2018 Apr 12;13(4):e0196002. doi: 10.1371/journal.pone.0196002. eCollection 2018.


Toxic metals in ayurvedic preparations from a public health lead poisoning cluster investigation.

Mikulski MA, Wichman MD, Simmons DL, Pham AN, Clottey V, Fuortes LJ.

Int J Occup Environ Health. 2017 Jul;23(3):187-192. doi: 10.1080/10773525.2018.1447880. Epub 2018 Mar 12.


Effect of Intensive Blood-Pressure Treatment on Patient-Reported Outcomes.

Berlowitz DR, Foy CG, Kazis LE, Bolin LP, Conroy MB, Fitzpatrick P, Gure TR, Kimmel PL, Kirchner K, Morisky DE, Newman J, Olney C, Oparil S, Pajewski NM, Powell J, Ramsey T, Simmons DL, Snyder J, Supiano MA, Weiner DE, Whittle J; SPRINT Research Group.

N Engl J Med. 2017 Aug 24;377(8):733-744. doi: 10.1056/NEJMoa1611179.


Metabolic syndrome cluster does not provide incremental prognostic information in patients with stable cardiovascular disease: A post hoc analysis of the AIM-HIGH trial.

Lyubarova R, Robinson JG, Miller M, Simmons DL, Xu P, Abramson BL, Elam MB, Brown TM, McBride R, Fleg JL, Desvigne-Nickens P, Ayenew W, Boden WE; Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides and Impact on Global Health Outcomes (AIM-HIGH) Investigators.

J Clin Lipidol. 2017 Sep - Oct;11(5):1201-1211. doi: 10.1016/j.jacl.2017.06.017. Epub 2017 Jul 5.


Effect of Intensive Versus Standard Blood Pressure Treatment According to Baseline Prediabetes Status: A Post Hoc Analysis of a Randomized Trial.

Bress AP, King JB, Kreider KE, Beddhu S, Simmons DL, Cheung AK, Zhang Y, Doumas M, Nord J, Sweeney ME, Taylor AA, Herring C, Kostis WJ, Powell J, Rastogi A, Roumie CL, Wiggers A, Williams JS, Yunis R, Zias A, Evans GW, Greene T, Rocco MV, Cushman WC, Reboussin DM, Feinglos MN, Papademetriou V; SPRINT Research Group.

Diabetes Care. 2017 Aug 9. pii: dc170885. doi: 10.2337/dc17-0885. [Epub ahead of print]


High prevalence of elevated blood lead levels in both rural and urban Iowa newborns: Spatial patterns and area-level covariates.

Carrel M, Zahrieh D, Young SG, Oleson J, Ryckman KK, Wels B, Simmons DL, Saftlas A.

PLoS One. 2017 May 16;12(5):e0177930. doi: 10.1371/journal.pone.0177930. eCollection 2017. Erratum in: PLoS One. 2018 Apr 12;13(4):e0196002.


A Randomized Controlled Trial of the Effects of Febuxostat Therapy on Adipokines and Markers of Kidney Fibrosis in Asymptomatic Hyperuricemic Patients With Diabetic Nephropathy.

Beddhu S, Filipowicz R, Wang B, Wei G, Chen X, Roy AC, DuVall SL, Farrukh H, Habib AN, Bjordahl T, Simmons DL, Munger M, Stoddard G, Kohan DE, Greene T, Huang Y.

Can J Kidney Health Dis. 2016 Dec 5;3:2054358116675343. doi: 10.1177/2054358116675343. eCollection 2016.


Sellar Wegener Granulomatosis Masquerading as Cabergoline-Resistant Prolactinoma.

Eli IM, Raheja A, Corn HJ, Simmons DL, Palmer CA, Couldwell WT.

World Neurosurg. 2016 Nov;95:622.e1-622.e5. doi: 10.1016/j.wneu.2016.07.108. Epub 2016 Aug 10.


Primary pituitary diffuse large B-cell lymphoma with somatotroph hyperplasia and acromegaly: case report.

Ravindra VM, Raheja A, Corn H, Driscoll M, Welt C, Simmons DL, Couldwell WT.

J Neurosurg. 2017 May;126(5):1725-1730. doi: 10.3171/2016.5.JNS16828. Epub 2016 Aug 12.


Resetting the bar: Establishing baselines for persistent contaminants after Hurricane Sandy in the coastal environments of New Jersey and New York, USA.

Reilly TJ, Focazio MJ, Simmons DL.

Mar Pollut Bull. 2016 Jun 30;107(2):414-21. doi: 10.1016/j.marpolbul.2016.05.045. Epub 2016 Jun 6. No abstract available.


Haptoglobin Genotype as a Determinant of Benefit or Harm From Niacin for Participants With Diabetes.

Asleh R, Levy NS, Doros G, Costacou T, Robinson JG, Blum S, Goldenstein H, Boden WE, Simmons DL, Lacy MA, Grunberger G, Anderson TJ, Levy AP.

J Am Coll Cardiol. 2016 May 31;67(21):2553-4. doi: 10.1016/j.jacc.2016.03.533. No abstract available.


Effects of Extended-Release Niacin Added to Simvastatin/Ezetimibe on Glucose and Insulin Values in AIM-HIGH.

Goldberg RB, Bittner VA, Dunbar RL, Fleg JL, Grunberger G, Guyton JR, Leiter LA, McBride R, Robinson JG, Simmons DL, Wysham C, Xu P, Boden WE.

Am J Med. 2016 Jul;129(7):753.e13-22. doi: 10.1016/j.amjmed.2016.02.039. Epub 2016 Mar 29.


Assessment of the Mitigative Capacity of Dietary Zinc on PCB126 Hepatotoxicity and the Contribution of Zinc to Toxicity.

Klaren WD, Gibson-Corley KN, Wels B, Simmons DL, McCormick ML, Spitz DR, Robertson LW.

Chem Res Toxicol. 2016 May 16;29(5):851-9. doi: 10.1021/acs.chemrestox.6b00022. Epub 2016 Mar 23.


Dietary Manganese Modulates PCB126 Toxicity, Metal Status, and MnSOD in the Rat.

Wang B, Klaren WD, Wels BR, Simmons DL, Olivier AK, Wang K, Robertson LW, Ludewig G.

Toxicol Sci. 2016 Mar;150(1):15-26. doi: 10.1093/toxsci/kfv312. Epub 2015 Dec 10.


Progression of micronutrient alteration and hepatotoxicity following acute PCB126 exposure.

Klaren WD, Gadupudi GS, Wels B, Simmons DL, Olivier AK, Robertson LW.

Toxicology. 2015 Dec 2;338:1-7. doi: 10.1016/j.tox.2015.09.004. Epub 2015 Sep 26.


Effects of TZD Use and Discontinuation on Fracture Rates in ACCORD Bone Study.

Schwartz AV, Chen H, Ambrosius WT, Sood A, Josse RG, Bonds DE, Schnall AM, Vittinghoff E, Bauer DC, Banerji MA, Cohen RM, Hamilton BP, Isakova T, Sellmeyer DE, Simmons DL, Shibli-Rahhal A, Williamson JD, Margolis KL.

J Clin Endocrinol Metab. 2015 Nov;100(11):4059-66. doi: 10.1210/jc.2015-1215. Epub 2015 Aug 25.


Uncontrolled combustion of shredded tires in a landfill - Part 1: Characterization of gaseous and particulate emissions.

Downard J, Singh A, Bullard R, Jayarathne T, Rathnayake C, Simmons DL, Wels BR, Spak SN, Peters T, Beardsley D, Stanier C, Stone EA.

Atmos Environ (1994). 2015 Mar 1;104:195-204.


Intensive blood pressure control, falls, and fractures in patients with type 2 diabetes: the ACCORD trial.

Margolis KL, Palermo L, Vittinghoff E, Evans GW, Atkinson HH, Hamilton BP, Josse RG, O'Connor PJ, Simmons DL, Tiktin M, Schwartz AV.

J Gen Intern Med. 2014 Dec;29(12):1599-606. doi: 10.1007/s11606-014-2961-3. Epub 2014 Aug 16.


Durable change in glycaemic control following intensive management of type 2 diabetes in the ACCORD clinical trial.

Punthakee Z, Miller ME, Simmons DL, Riddle MC, Ismail-Beigi F, Brillon DJ, Bergenstal RM, Savage PJ, Hramiak I, Largay JF, Sood A, Gerstein HC; ACCORD Group of Investigators.

Diabetologia. 2014 Oct;57(10):2030-7. doi: 10.1007/s00125-014-3318-5. Epub 2014 Jul 2.


Paradoxical reduction in HDL-C with fenofibrate and thiazolidinedione therapy in type 2 diabetes: the ACCORD Lipid Trial.

Linz PE, Lovato LC, Byington RP, O'Connor PJ, Leiter LA, Weiss D, Force RW, Crouse JR, Ismail-Beigi F, Simmons DL, Papademetriou V, Ginsberg HN, Elam MB.

Diabetes Care. 2014;37(3):686-93. doi: 10.2337/dc13-0790. Epub 2013 Dec 2.


Low- and high-cocaine locomotor responding rats differ in reinstatement of cocaine seeking and striatal mGluR5 protein expression.

Simmons DL, Mandt BH, Ng CM, Richards TL, Yamamoto DJ, Zahniser NR, Allen RM.

Neuropharmacology. 2013 Dec;75:347-55. doi: 10.1016/j.neuropharm.2013.08.001. Epub 2013 Aug 22.


Does dietary copper supplementation enhance or diminish PCB126 toxicity in the rodent liver?

Lai IK, Klaren WD, Li M, Wels B, Simmons DL, Olivier AK, Haschek WM, Wang K, Ludewig G, Robertson LW.

Chem Res Toxicol. 2013 May 20;26(5):634-44. doi: 10.1021/tx400049s. Epub 2013 Apr 15.


Targeting kinases: a new approach to treating inflammatory rheumatic diseases.

Simmons DL.

Curr Opin Pharmacol. 2013 Jun;13(3):426-34. doi: 10.1016/j.coph.2013.02.008. Epub 2013 Mar 19. Review.


Cardiovascular risk assessment: addition of CKD and race to the Framingham equation.

Drawz PE, Baraniuk S, Davis BR, Brown CD, Colon PJ Sr, Cujyet AB, Dart RA, Graumlich JF, Henriquez MA, Moloo J, Sakalayen MG, Simmons DL, Stanford C, Sweeney ME, Wong ND, Rahman M.

Am Heart J. 2012 Dec;164(6):925-31.e2. doi: 10.1016/j.ahj.2012.09.003. Epub 2012 Oct 29.


Intensive glycemic control is not associated with fractures or falls in the ACCORD randomized trial.

Schwartz AV, Margolis KL, Sellmeyer DE, Vittinghoff E, Ambrosius WT, Bonds DE, Josse RG, Schnall AM, Simmons DL, Hue TF, Palermo L, Hamilton BP, Green JB, Atkinson HH, O'Connor PJ, Force RW, Bauer DC.

Diabetes Care. 2012 Jul;35(7):1525-31. doi: 10.2337/dc11-2184.


Postsurgical treatment of early-stage breast cancer with electronic brachytherapy: outcomes and health-related quality of life at 1 year.

Patel RR, Beitsch PD, Nichols TD, Lorenzetti JD, Wurzer JC, Tucker JC, Nunn GW, Laduzinsky SJ, Kugler MA, Simmons DL, Gilligan MS, Roy T, Foley JK, Thropay JP, Odou MW, Bornstein BA, Tito EP, Chadha M, Boolbol SK, Lane SC, White JG.

Am J Clin Oncol. 2013 Oct;36(5):430-5. doi: 10.1097/COC.0b013e31825493bb.


Severe hypoglycemia symptoms, antecedent behaviors, immediate consequences and association with glycemia medication usage: Secondary analysis of the ACCORD clinical trial data.

Bonds DE, Miller ME, Dudl J, Feinglos M, Ismail-Beigi F, Malozowski S, Seaquist E, Simmons DL, Sood A.

BMC Endocr Disord. 2012 May 30;12:5. doi: 10.1186/1472-6823-12-5.


Depression predicts all-cause mortality: epidemiological evaluation from the ACCORD HRQL substudy.

Sullivan MD, O'Connor P, Feeney P, Hire D, Simmons DL, Raisch DW, Fine LJ, Narayan KM, Ali MK, Katon WJ.

Diabetes Care. 2012 Aug;35(8):1708-15. doi: 10.2337/dc11-1791. Epub 2012 May 22.


Effect of intensive versus standard blood pressure control on depression and health-related quality of life in type 2 diabetes: the ACCORD trial.

O'Connor PJ, Narayan KM, Anderson R, Feeney P, Fine L, Ali MK, Simmons DL, Hire DG, Sperl-Hillen JM, Katz LA, Margolis KL, Sullivan MD.

Diabetes Care. 2012 Jul;35(7):1479-81. doi: 10.2337/dc11-1868. Epub 2012 May 14.


Long-term effects of incident diabetes mellitus on cardiovascular outcomes in people treated for hypertension: the ALLHAT Diabetes Extension Study.

Barzilay JI, Davis BR, Pressel SL, Cutler JA, Einhorn PT, Black HR, Cushman WC, Ford CE, Margolis KL, Moloo J, Oparil S, Piller LB, Simmons DL, Sweeney ME, Whelton PK, Wong ND, Wright JT Jr; ALLHAT Collaborative Research Group.

Circ Cardiovasc Qual Outcomes. 2012 Mar 1;5(2):153-62. doi: 10.1161/CIRCOUTCOMES.111.962522. Epub 2012 Mar 6.


Glycaemia and correlates of patient-reported outcomes in ACCORD trial participants.

Ali MK, Feeney P, Hire D, Simmons DL, O'Connor PJ, Ganz-Lord F, Goff D Jr, Zhang P, Anderson RT, Narayan KM, Sullivan MD.

Diabet Med. 2012 Jul;29(7):e67-74. doi: 10.1111/j.1464-5491.2011.03532.x.


Effect of intensive glycemic lowering on health-related quality of life in type 2 diabetes: ACCORD trial.

Anderson RT, Narayan KM, Feeney P, Goff D Jr, Ali MK, Simmons DL, Sperl-Hillen JA, Bigger T, Cuddihy R, O'Conner PJ, Sood A, Zhang P, Sullivan MD; Action to Control Cardiovascular Risk in Diabetes (ACCORD) Investigators.

Diabetes Care. 2011 Apr;34(4):807-12. doi: 10.2337/dc10-1926. Epub 2011 Feb 23.


Expression of cyclooxygenase isoforms in the baculovirus expression system.

Hunter JC, Myres NM, Simmons DL.

Methods Mol Biol. 2010;644:45-54. doi: 10.1007/978-1-59745-364-6_5.


Striatal regulation of ΔFosB, FosB, and cFos during cocaine self-administration and withdrawal.

Larson EB, Akkentli F, Edwards S, Graham DL, Simmons DL, Alibhai IN, Nestler EJ, Self DW.

J Neurochem. 2010 Oct;115(1):112-22. doi: 10.1111/j.1471-4159.2010.06907.x. Epub 2010 Aug 3.


The N-terminus of COX-1 and its effect on cyclooxygenase-1 catalytic activity.

Xu Y, Phipps S, Turner MJ, Simmons DL.

J Genet Genomics. 2010 Feb;37(2):117-23. doi: 10.1016/S1673-8527(09)60030-8.


The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study.

Bonds DE, Miller ME, Bergenstal RM, Buse JB, Byington RP, Cutler JA, Dudl RJ, Ismail-Beigi F, Kimel AR, Hoogwerf B, Horowitz KR, Savage PJ, Seaquist ER, Simmons DL, Sivitz WI, Speril-Hillen JM, Sweeney ME.

BMJ. 2010 Jan 8;340:b4909. doi: 10.1136/bmj.b4909.


Answering the burning question of how transient receptor potential vanilloid-1 channel antagonists cause unwanted hyperthermia.

Ayoub SS, Hunter JC, Simmons DL.

Pharmacol Rev. 2009 Sep;61(3):225-7. doi: 10.1124/pr.109.001875.


Cyclooxygenase-1 or -2--which one mediates lipopolysaccharide-induced hypothermia?

Steiner AA, Hunter JC, Phipps SM, Nucci TB, Oliveira DL, Roberts JL, Scheck AC, Simmons DL, Romanovsky AA.

Am J Physiol Regul Integr Comp Physiol. 2009 Aug;297(2):R485-94. doi: 10.1152/ajpregu.91026.2008. Epub 2009 Jun 10.


Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways.

Filer A, Bik M, Parsonage GN, Fitton J, Trebilcock E, Howlett K, Cook M, Raza K, Simmons DL, Thomas AM, Salmon M, Scheel-Toellner D, Lord JM, Rabinovich GA, Buckley CD.

Arthritis Rheum. 2009 Jun;60(6):1604-14. doi: 10.1002/art.24574.


Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior.

Bachtell RK, Choi KH, Simmons DL, Falcon E, Monteggia LM, Neve RL, Self DW.

Eur J Neurosci. 2008 May;27(9):2229-40. doi: 10.1111/j.1460-9568.2008.06199.x. Epub 2008 Apr 22.


Clinical outcomes by race in hypertensive patients with and without the metabolic syndrome: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Wright JT Jr, Harris-Haywood S, Pressel S, Barzilay J, Baimbridge C, Bareis CJ, Basile JN, Black HR, Dart R, Gupta AK, Hamilton BP, Einhorn PT, Haywood LJ, Jafri SZ, Louis GT, Whelton PK, Scott CL, Simmons DL, Stanford C, Davis BR.

Arch Intern Med. 2008 Jan 28;168(2):207-17. doi: 10.1001/archinternmed.2007.66.


Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes.

Govindarajan R, Ratnasinghe L, Simmons DL, Siegel ER, Midathada MV, Kim L, Kim PJ, Owens RJ, Lang NP.

J Clin Oncol. 2007 Apr 20;25(12):1476-81.


Charcot arthropathy. An often overlooked complication of diabetes mellitus.

Choksi P, Thomas R, Simmons DL.

J Ark Med Soc. 2007 Mar;103(9):229-31.


Trifunctional inhibition of COX-2 by extracts of Lonicera japonica: direct inhibition, transcriptional and post-transcriptional down regulation.

Xu Y, Oliverson BG, Simmons DL.

J Ethnopharmacol. 2007 May 22;111(3):667-70. Epub 2007 Jan 19.


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