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Items: 50

1.

Fair selection of participants in clinical trials: The challenge to push the envelope further.

Davies JC, Scott S, Dobra R, Brendell R, Brownlee K, Carr SB, Cosgriff R, Simmonds NJ; London Network of Clinical Trials Accelerator Platform sites, Jahan R, Jones A, Matthews J, Brown S, Galono K, Miles K, Pao C, Shafi N, Watson D, Orchard C, Davies G, Pike K, Shah S, Bossley CJ, Fong T, Macedo P, Ruiz G, Waller M, Baker L.

J Cyst Fibros. 2019 Aug 9. pii: S1569-1993(19)30825-2. doi: 10.1016/j.jcf.2019.07.004. [Epub ahead of print] No abstract available.

PMID:
31405729
2.

Nasal potential difference in suspected cystic fibrosis patients with 5T polymorphism.

Aalbers BL, Yaakov Y, Derichs N, Simmonds NJ, De Wachter E, Melotti P, De Boeck K, Leal T, Tümmler B, Wilschanski M, Bronsveld I.

J Cyst Fibros. 2019 Jul 19. pii: S1569-1993(19)30822-7. doi: 10.1016/j.jcf.2019.07.001. [Epub ahead of print]

PMID:
31331863
3.

Reduced exercise ventilatory efficiency in adults with cystic fibrosis and normal to moderately impaired lung function.

Di Paolo M, Teopompi E, Savi D, Crisafulli E, Longo C, Tzani P, Longo F, Ielpo A, Pisi G, Cimino G, Simmonds NJ, Neder JA, Chetta A, Palange P.

J Appl Physiol (1985). 2019 Aug 1;127(2):501-512. doi: 10.1152/japplphysiol.00030.2019. Epub 2019 Jun 20.

PMID:
31219769
4.

Who and why; sharing our experiences of developing a standard operating procedure (SOP) to allocate screening slots for highly competitive cystic fibrosis trials.

Dobra R, Scott S, Davies JC, Simmonds NJ.

J Cyst Fibros. 2019 May 3. pii: S1569-1993(19)30068-2. doi: 10.1016/j.jcf.2019.04.008. [Epub ahead of print] No abstract available.

PMID:
31060801
5.

Is it cystic fibrosis? The challenges of diagnosing cystic fibrosis.

Simmonds NJ.

Paediatr Respir Rev. 2019 Feb 28. pii: S1526-0542(19)30018-1. doi: 10.1016/j.prrv.2019.02.004. [Epub ahead of print] Review.

PMID:
30967347
6.

The emerging burden of liver disease in cystic fibrosis patients: A UK nationwide study.

Toledano MB, Mukherjee SK, Howell J, Westaby D, Khan SA, Bilton D, Simmonds NJ.

PLoS One. 2019 Apr 4;14(4):e0212779. doi: 10.1371/journal.pone.0212779. eCollection 2019.

7.

Effects of Lumacaftor/Ivacaftor on physical activity and exercise tolerance in three adults with cystic fibrosis.

Savi D, Schiavetto S, Simmonds NJ, Righelli D, Palange P.

J Cyst Fibros. 2019 May;18(3):420-424. doi: 10.1016/j.jcf.2019.03.001. Epub 2019 Mar 14.

PMID:
30879989
8.

Non-invasive ventilation and clinical outcomes in cystic fibrosis: Findings from the UK CF registry.

Archangelidi O, Carr SB, Simmonds NJ, Bilton D, Banya W, Cullinan P; CF-EpiNet.

J Cyst Fibros. 2018 Nov 28. pii: S1569-1993(18)30934-2. doi: 10.1016/j.jcf.2018.11.006. [Epub ahead of print]

PMID:
30503032
9.

Use of a rare disease patient registry in long-term post-authorisation drug studies: a model for collaboration with industry.

Bilton D, Caine N, Cunningham S, Simmonds NJ, Cosgriff R, Carr SB.

Lancet Respir Med. 2018 Jul;6(7):495-496. doi: 10.1016/S2213-2600(18)30192-9. Epub 2018 May 4. Review. No abstract available.

PMID:
29735358
10.

Airway persistence by the emerging multi-azole-resistant Rasamsonia argillacea complex in cystic fibrosis.

Abdolrasouli A, Bercusson AC, Rhodes JL, Hagen F, Buil JB, Tang AYY, de Boer LL, Shah A, Milburn AJ, Elborn JS, Jones AL, Meis JF, Fisher MC, Schelenz S, Simmonds NJ, Armstrong-James D.

Mycoses. 2018 Sep;61(9):665-673. doi: 10.1111/myc.12789. Epub 2018 Jun 20.

11.

Is daily physical activity affected by dynamic hyperinflation in adults with cystic fibrosis?

Savi D, Di Paolo M, Simmonds NJ, Pascucci C, Quattrucci S, Palange P.

BMC Pulm Med. 2018 Apr 19;18(1):60. doi: 10.1186/s12890-018-0623-7.

12.

The Man in the Paper Mask: One (Mask) for All and All for . . . Cystic Fibrosis?

Simmonds NJ, Bush A.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):281-283. doi: 10.1164/rccm.201710-2001ED. No abstract available.

13.

Burkholderia cepacia complex and limited cutaneous vasculitis in patients with cystic fibrosis: a case series.

Kayria M, Chris O, Dhasmana DJ, Nilesh M, Hodson ME, Khin G, Diana B, Simmonds NJ.

JRSM Open. 2017 Apr 3;8(4):2054270417692732. doi: 10.1177/2054270417692732. eCollection 2017 Apr.

14.

A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis.

Alton EWFW, Armstrong DK, Ashby D, Bayfield KJ, Bilton D, Bloomfield EV, Boyd AC, Brand J, Buchan R, Calcedo R, Carvelli P, Chan M, Cheng SH, Collie DS, Cunningham S, Davidson HE, Davies G, Davies JC, Davies LA, Dewar MH, Doherty A, Donovan J, Dwyer NS, Elgmati HI, Featherstone RF, Gavino J, Gea-Sorli S, Geddes DM, Gibson JSR, Gill DR, Greening AP, Griesenbach U, Hansell DM, Harman K, Higgins TE, Hodges SL, Hyde SC, Hyndman L, Innes JA, Jacob J, Jones N, Keogh BF, Limberis MP, Lloyd-Evans P, Maclean AW, Manvell MC, McCormick D, McGovern M, McLachlan G, Meng C, Montero MA, Milligan H, Moyce LJ, Murray GD, Nicholson AG, Osadolor T, Parra-Leiton J, Porteous DJ, Pringle IA, Punch EK, Pytel KM, Quittner AL, Rivellini G, Saunders CJ, Scheule RK, Sheard S, Simmonds NJ, Smith K, Smith SN, Soussi N, Soussi S, Spearing EJ, Stevenson BJ, Sumner-Jones SG, Turkkila M, Ureta RP, Waller MD, Wasowicz MY, Wilson JM, Wolstenholme-Hogg P; on behalf of the UK Cystic Fibrosis Gene Therapy Consortium.

Southampton (UK): NIHR Journals Library; 2016 Jul.

15.

Phenotypic variability of R117H-CFTR expression within monozygotic twins.

Waller MD, Simmonds NJ.

Paediatr Respir Rev. 2016 Aug;20 Suppl:21-3. doi: 10.1016/j.prrv.2016.06.009. Epub 2016 Jun 15. Review.

PMID:
27364092
16.

Aminoglycosides: old friend…new foe?

Simmonds NJ, Thomson AH.

J Cyst Fibros. 2016 Jul;15(4):411-2. doi: 10.1016/j.jcf.2016.05.011. Epub 2016 Jun 2. No abstract available.

17.

Response to Letter to the Editor: HbA1c as a screening tool for cystic fibrosis related diabetes: Response to letters by Widger et al. and Schnyder et al.

Burgess JC, Bridges N, Winston B, Gyi KM, Hodson ME, Bilton D, Simmonds NJ.

J Cyst Fibros. 2016 Mar;15(2):265-6. doi: 10.1016/j.jcf.2015.12.001. Epub 2015 Dec 23. No abstract available.

18.

Cystic Fibrosis Papers of the Year, 2013-2014.

Simmonds NJ.

Paediatr Respir Rev. 2015 Oct;16 Suppl 1:9-11. doi: 10.1016/j.prrv.2015.07.008. Epub 2015 Sep 26. Review.

PMID:
26410284
19.

Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial.

Alton EWFW, Armstrong DK, Ashby D, Bayfield KJ, Bilton D, Bloomfield EV, Boyd AC, Brand J, Buchan R, Calcedo R, Carvelli P, Chan M, Cheng SH, Collie DDS, Cunningham S, Davidson HE, Davies G, Davies JC, Davies LA, Dewar MH, Doherty A, Donovan J, Dwyer NS, Elgmati HI, Featherstone RF, Gavino J, Gea-Sorli S, Geddes DM, Gibson JSR, Gill DR, Greening AP, Griesenbach U, Hansell DM, Harman K, Higgins TE, Hodges SL, Hyde SC, Hyndman L, Innes JA, Jacob J, Jones N, Keogh BF, Limberis MP, Lloyd-Evans P, Maclean AW, Manvell MC, McCormick D, McGovern M, McLachlan G, Meng C, Montero MA, Milligan H, Moyce LJ, Murray GD, Nicholson AG, Osadolor T, Parra-Leiton J, Porteous DJ, Pringle IA, Punch EK, Pytel KM, Quittner AL, Rivellini G, Saunders CJ, Scheule RK, Sheard S, Simmonds NJ, Smith K, Smith SN, Soussi N, Soussi S, Spearing EJ, Stevenson BJ, Sumner-Jones SG, Turkkila M, Ureta RP, Waller MD, Wasowicz MY, Wilson JM, Wolstenholme-Hogg P; UK Cystic Fibrosis Gene Therapy Consortium.

Lancet Respir Med. 2015 Sep;3(9):684-691. doi: 10.1016/S2213-2600(15)00245-3. Epub 2015 Jul 3. Erratum in: Lancet Respir Med. 2015 Sep;3(9):e33.

20.

HbA1c as a screening tool for cystic fibrosis related diabetes.

Burgess JC, Bridges N, Banya W, Gyi KM, Hodson ME, Bilton D, Simmonds NJ.

J Cyst Fibros. 2016 Mar;15(2):251-7. doi: 10.1016/j.jcf.2015.03.013. Epub 2015 Apr 11.

21.

Eradication of respiratory tract MRSA at a large adult cystic fibrosis centre.

Hall H, Gadhok R, Alshafi K, Bilton D, Simmonds NJ.

Respir Med. 2015 Mar;109(3):357-63. doi: 10.1016/j.rmed.2015.01.013. Epub 2015 Feb 3.

22.

Aspergillus and cystic fibrosis: old disease - new classifications.

Felton IC, Simmonds NJ.

Curr Opin Pulm Med. 2014 Nov;20(6):632-8. doi: 10.1097/MCP.0000000000000106. Review.

PMID:
25229669
23.

Effects of ivacaftor in patients with cystic fibrosis who carry the G551D mutation and have severe lung disease.

Barry PJ, Plant BJ, Nair A, Bicknell S, Simmonds NJ, Bell NJ, Shafi NT, Daniels T, Shelmerdine S, Felton I, Gunaratnam C, Jones AM, Horsley AR.

Chest. 2014 Jul;146(1):152-158. doi: 10.1378/chest.13-2397.

PMID:
24522694
24.

A molecular comparison of microbial communities in bronchiectasis and cystic fibrosis.

Duff RM, Simmonds NJ, Davies JC, Wilson R, Alton EW, Pantelidis P, Cox MJ, Cookson WO, Bilton D, Moffatt MF.

Eur Respir J. 2013 Apr;41(4):991-3. doi: 10.1183/09031936.00052712. No abstract available.

25.

The destructive combination of Scediosporium apiosperum lung disease and exuberant inflammation in cystic fibrosis.

Russell GK, Gadhok R, Simmonds NJ.

Paediatr Respir Rev. 2013 May;14 Suppl 1:22-5. doi: 10.1016/j.prrv.2013.02.004. Epub 2013 Mar 18.

PMID:
23518310
26.

Ageing in cystic fibrosis and long-term survival.

Simmonds NJ.

Paediatr Respir Rev. 2013 May;14 Suppl 1:6-9. doi: 10.1016/j.prrv.2013.01.007. Epub 2013 Feb 24. Review.

PMID:
23497942
27.

Cystic fibrosis: management of haemoptysis.

Hurt K, Simmonds NJ.

Paediatr Respir Rev. 2012 Dec;13(4):200-5. doi: 10.1016/j.prrv.2012.01.003. Epub 2012 Feb 28. Review.

PMID:
23069116
28.

Diagnosing cystic fibrosis: what are we sweating about?

Simmonds NJ, Bush A.

Thorax. 2012 Jul;67(7):571-3. doi: 10.1136/thoraxjnl-2012-201758. Epub 2012 Apr 17. No abstract available.

PMID:
22511297
29.

Hot off the breath: 'I've a cost for'--the 64 million dollar question.

Bush A, Simmonds NJ.

Thorax. 2012 May;67(5):382-4. doi: 10.1136/thoraxjnl-2012-201798. Epub 2012 Mar 10. No abstract available.

PMID:
22407889
30.

The prevalence of "risky behaviour" in adults with cystic fibrosis.

Mc Ewan FA, Hodson ME, Simmonds NJ.

J Cyst Fibros. 2012 Jan;11(1):56-8. doi: 10.1016/j.jcf.2011.09.002. Epub 2011 Oct 2.

31.

Improved survival at low lung function in cystic fibrosis: cohort study from 1990 to 2007.

George PM, Banya W, Pareek N, Bilton D, Cullinan P, Hodson ME, Simmonds NJ.

BMJ. 2011 Feb 28;342:d1008. doi: 10.1136/bmj.d1008.

32.

Cystic fibrosis and survival to 40 years: a study of cystic fibrosis transmembrane conductance regulator function.

Simmonds NJ, D'Souza L, Roughton M, Alton EW, Davies JC, Hodson ME.

Eur Respir J. 2011 May;37(5):1076-82. doi: 10.1183/09031936.00079010. Epub 2010 Sep 16.

33.

Cystic fibrosis and survival to 40 years: a case-control study.

Simmonds NJ, Macneill SJ, Cullinan P, Hodson ME.

Eur Respir J. 2010 Dec;36(6):1277-83. doi: 10.1183/09031936.00001710. Epub 2010 Apr 8.

34.

Ethical issues in nutrition support: a view from the coalface.

Simmonds NJ.

Frontline Gastroenterol. 2010 Apr;1(1):7-12. doi: 10.1136/fg.2009.000240. Epub 2010 Apr 1. Review.

35.

A woman with cystic fibrosis, severe hypoxaemia, an atrial thrombus and a patent foramen ovale: a case report.

Simmonds NJ, Wyatt H, Patel R, Hodson ME, Gyi KM.

J Med Case Rep. 2009 Jul 20;3:8582. doi: 10.4076/1752-1947-3-8582.

36.

Trends in pathogens colonising the respiratory tract of adult patients with cystic fibrosis, 1985-2005.

Millar FA, Simmonds NJ, Hodson ME.

J Cyst Fibros. 2009 Dec;8(6):386-91. doi: 10.1016/j.jcf.2009.08.003. Epub 2009 Sep 8.

37.

Growing old with cystic fibrosis - the characteristics of long-term survivors of cystic fibrosis.

Simmonds NJ, Cullinan P, Hodson ME.

Respir Med. 2009 Apr;103(4):629-35. doi: 10.1016/j.rmed.2008.10.011. Epub 2008 Nov 20.

38.

Cystic fibrosis, a Burkholderia cenocepacia chest wall abscess and rapid clinical deterioration.

Simmonds NJ, Gyi KM.

J R Soc Med. 2008 Jul;101 Suppl 1:S46-50. doi: 10.1258/jrsm.2008.s18011. No abstract available.

39.

An international/multicentre report on patients with cystic fibrosis (CF) over the age of 40 years.

Hodson ME, Simmonds NJ, Warwick WJ, Tullis E, Castellani C, Assael B, Dodge JA, Corey M; International Study Of Aging In Cystic Fibrosis.

J Cyst Fibros. 2008 Nov;7(6):537-42. doi: 10.1016/j.jcf.2008.06.003. Epub 2008 Aug 19.

40.

Radiotherapy: a novel treatment for pneumothorax.

Ong YE, Sheth A, Simmonds NJ, Heenan S, Allan R, Glees JP, Madden BP.

Eur Respir J. 2006 Feb;27(2):427-9.

41.
42.

Helicobacter pylori stimulates antral mucosal reactive oxygen metabolite production in vivo.

Davies GR, Simmonds NJ, Stevens TR, Sheaff MT, Banatvala N, Laurenson IF, Blake DR, Rampton DS.

Gut. 1994 Feb;35(2):179-85.

43.

Inflammatory bowel disease--a radical view.

Simmonds NJ, Rampton DS.

Gut. 1993 Jul;34(7):865-8. No abstract available.

44.

Comparison of nisoldipine and nifedipine as additional treatment in hypertension inadequately controlled by atenolol.

Hoffbrand BI, Earle KA, Nievel JG, Restrick LJ, Simmonds NJ.

Postgrad Med J. 1993 Feb;69(808):117-20.

45.

Mucosal reactive oxygen metabolite production in duodenal ulcer disease.

Davies GR, Simmonds NJ, Stevens TR, Grandison A, Blake DR, Rampton DS.

Gut. 1992 Nov;33(11):1467-72.

46.

Chemiluminescence assay of mucosal reactive oxygen metabolites in inflammatory bowel disease.

Simmonds NJ, Allen RE, Stevens TR, Van Someren RN, Blake DR, Rampton DS.

Gastroenterology. 1992 Jul;103(1):186-96.

PMID:
1319369
47.

Controlled trial of endoscopic injection treatment for bleeding from peptic ulcers with visible vessels.

Oxner RB, Simmonds NJ, Gertner DJ, Nightingale JM, Burnham WR.

Lancet. 1992 Apr 18;339(8799):966-8.

PMID:
1348805
48.

Circulating von Willebrand factor in inflammatory bowel disease.

Stevens TR, James JP, Simmonds NJ, McCarthy DA, Laurenson IF, Maddison PJ, Rampton DS.

Gut. 1992 Apr;33(4):502-6.

49.

'Lupus lymphadenitis' simulating a strangulated femoral hernia in a patient with mixed connective tissue disease.

Simmonds NJ, Hoffbrand BI.

Ann Rheum Dis. 1991 May;50(5):337. No abstract available.

50.

Contracturing granulomatous myositis: a separate entity.

Simmonds NJ, Hoffbrand BI.

J Neurol Neurosurg Psychiatry. 1990 Nov;53(11):998-1000.

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