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Items: 16


Safety and tolerability of nintedanib for the treatment of idiopathic pulmonary fibrosis in routine UK clinical practice.

Fletcher SV, Jones MG, Renzoni EA, Parfrey H, Hoyles RK, Spinks K, Kokosi M, Kwok A, Warburton C, Titmuss V, Thillai M, Simler N, Maher TM, Brereton CJ, Chua F, Wells AU, Richeldi L, Spencer LG.

ERJ Open Res. 2018 Oct 19;4(4). pii: 00049-2018. doi: 10.1183/23120541.00049-2018. eCollection 2018 Oct.


Severe Colitis Associated with Pirfenidone Use in Idiopathic Pulmonary Fibrosis.

Fiddler CA, Simler N, Parfrey H, Miremadi A, Chilvers ER.

Ann Am Thorac Soc. 2016 Aug;13(8):1430-2. doi: 10.1513/AnnalsATS.201602-118LE. No abstract available.


A rare case of acute epiglottitis due to Staphylococcus aureus in an adult.

Harris C, Sharkey L, Koshy G, Simler N, Karas JA.

Infect Dis Rep. 2012 Jan 2;4(1):e3. doi: 10.4081/idr.2012.e3. eCollection 2012 Jan 2.


Hypoxia transiently affects skeletal muscle hypertrophy in a functional overload model.

Chaillou T, Koulmann N, Simler N, Meunier A, Serrurier B, Chapot R, Peinnequin A, Beaudry M, Bigard X.

Am J Physiol Regul Integr Comp Physiol. 2012 Mar 1;302(5):R643-54. doi: 10.1152/ajpregu.00262.2011. Epub 2011 Dec 21.


Control of gluconeogenic genes during intense/prolonged exercise: hormone-independent effect of muscle-derived IL-6 on hepatic tissue and PEPCK mRNA.

Banzet S, Koulmann N, Simler N, Sanchez H, Chapot R, Serrurier B, Peinnequin A, Bigard X.

J Appl Physiol (1985). 2009 Dec;107(6):1830-9. doi: 10.1152/japplphysiol.00739.2009. Epub 2009 Oct 22.


Management of accelerated pulmonary nodulosis following etanercept therapy in a patient with rheumatoid arthritis.

Watson P, Simler N, Screaton N, Lillicrap M.

Rheumatology (Oxford). 2008 Jun;47(6):928-9. doi: 10.1093/rheumatology/ken102. Epub 2008 Apr 2. No abstract available.


Hypoxic stimulus alters hypothalamic AMP-activated protein kinase phosphorylation concomitant to hypophagia.

Simler N, Malgoyre A, Koulmann N, Alonso A, Peinnequin A, Bigard AX.

J Appl Physiol (1985). 2007 Jun;102(6):2135-41. Epub 2007 Mar 1.


Cyclosporin A inhibits hypoxia-induced pulmonary hypertension and right ventricle hypertrophy.

Koulmann N, Novel-Chaté V, Peinnequin A, Chapot R, Serrurier B, Simler N, Richard H, Ventura-Clapier R, Bigard X.

Am J Respir Crit Care Med. 2006 Sep 15;174(6):699-705. Epub 2006 Jun 23.


Leptin receptor-deficient obese Zucker rats reduce their food intake in response to hypobaric hypoxia.

Simler N, Grosfeld A, Peinnequin A, Guerre-Millo M, Bigard AX.

Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E591-7. Epub 2005 Oct 18.


Fibre-type specificity of interleukin-6 gene transcription during muscle contraction in rat: association with calcineurin activity.

Banzet S, Koulmann N, Simler N, Birot O, Sanchez H, Chapot R, Peinnequin A, Bigard X.

J Physiol. 2005 Aug 1;566(Pt 3):839-47. Epub 2005 May 19.


Angiogenic cytokines in patients with idiopathic interstitial pneumonia.

Simler NR, Brenchley PE, Horrocks AW, Greaves SM, Hasleton PS, Egan JJ.

Thorax. 2004 Jul;59(7):581-5.


Vascular endothelial growth factor expression in heart of rats exposed to hypobaric hypoxia: differential response between mRNA and protein.

Birot OJ, Peinnequin A, Simler N, van Cuyck-Gandré H, Hamel R, Bigard XA.

J Cell Physiol. 2004 Jul;200(1):107-15.


The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats.

Simler NR, Howell DC, Marshall RP, Goldsack NR, Hasleton PS, Laurent GJ, Chambers RC, Egan JJ.

Eur Respir J. 2002 Jun;19(6):1124-7.


MK801 impairs thermoregulation in the heat.

Canini F, Simler N, Bourdon L.

Can J Physiol Pharmacol. 2002 Mar;80(3):226-32.


The 3' untranslated region of tumor necrosis factor-alpha is highly conserved in idiopathic pulmonary fibrosis (IPF).

Freeburn RW, Kendall H, Dobson L, Egan J, Simler NJ, Millar AB.

Eur Cytokine Netw. 2001 Mar;12(1):33-8.


Apoptosis signals in atopy and asthma measured with cDNA arrays.

Brutsche MH, Brutsche IC, Wood P, Brass A, Morrison N, Rattay M, Mogulkoc N, Simler N, Craven M, Custovic A, Egan JJ, Woodcock A.

Clin Exp Immunol. 2001 Feb;123(2):181-7.

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