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Development and pilot evaluation of a personalized decision support intervention for low risk prostate cancer patients.

Belkora J, Chan JM, Cooperberg MR, Neuhaus J, Stupar L, Weinberg T, Broering JM, Tenggara I, Cowan JE, Rosenfeld S, Kenfield SA, Van Blarigan EL, Simko JP, Witte J, Carroll PR.

Cancer Med. 2019 Nov 12. doi: 10.1002/cam4.2685. [Epub ahead of print]


The effect of gabapentin and pregabalin on bone turnover and bone strength: A prospective study in Wistar rats.

Simko J, Karesova I, Kremlacek J, Eva Z, Horacek J, Fekete S, Malakova J, Zivna H, Palicka V.

Pharmacol Rep. 2019 Aug 15;71(6):1213-1218. doi: 10.1016/j.pharep.2019.08.004. [Epub ahead of print]


Decipher identifies men with otherwise clinically favorable-intermediate risk disease who may not be good candidates for active surveillance.

Herlemann A, Huang HC, Alam R, Tosoian JJ, Kim HL, Klein EA, Simko JP, Chan JM, Lane BR, Davis JW, Davicioni E, Feng FY, McCue P, Kim H, Den RB, Bismar TA, Carroll PR, Cooperberg MR.

Prostate Cancer Prostatic Dis. 2019 Aug 27. doi: 10.1038/s41391-019-0167-9. [Epub ahead of print]


TP53 structural variants in metastatic prostatic carcinoma.

Sirohi D, Devine P, Grenert JP, van Ziffle J, Simko JP, Stohr BA.

PLoS One. 2019 Jun 19;14(6):e0218618. doi: 10.1371/journal.pone.0218618. eCollection 2019.


Identification and Characterization of Circulating Tumor Cells in Men Who have Undergone Prostatectomy for Clinically Localized, High Risk Prostate Cancer.

Friedlander TW, Welty C, Anantharaman A, Schonhoft JD, Jendrisak A, Lee J, Li P, Hough J, Stromlund A, Edwards M, Sangar S, Kobayashi Y, Simko J, Farrokhian N, Lindquist K, Greene S, Ontiveros P, Graf R, Rodriquez A, Suraneni M, Wang Y, Landers M, Carroll P, Cooperberg MR, Dittamore R, Paris PL.

J Urol. 2019 Oct;202(4):732-741. doi: 10.1097/JU.0000000000000393. Epub 2019 Sep 6.


A 17-Gene Genomic Prostate Score as a Predictor of Adverse Pathology in Men on Active Surveillance.

Kornberg Z, Cooperberg MR, Cowan JE, Chan JM, Shinohara K, Simko JP, Tenggara I, Carroll PR.

J Urol. 2019 Oct;202(4):702-709. doi: 10.1097/JU.0000000000000290. Epub 2019 Sep 6.


Correlation of a Commercial Genomic Risk Classifier with Histological Patterns in Prostate Cancer.

Greenland NY, Zhang L, Cowan JE, Carroll PR, Stohr BA, Simko JP.

J Urol. 2019 Jul;202(1):90-95. doi: 10.1097/JU.0000000000000175. Epub 2019 Jun 7.


Neoadjuvant sipuleucel-T induces both Th1 activation and immune regulation in localized prostate cancer.

Hagihara K, Chan S, Zhang L, Oh DY, Wei XX, Simko J, Fong L.

Oncoimmunology. 2018 Oct 1;8(1):e1486953. doi: 10.1080/2162402X.2018.1486953. eCollection 2019.


Phase I Study of CTT1057, an 18F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrane Antigen in Prostate Cancer.

Behr SC, Aggarwal R, VanBrocklin HF, Flavell RR, Gao K, Small EJ, Blecha J, Jivan S, Hope TA, Simko JP, Kurhanewicz J, Noworolski SM, Korn NJ, De Los Santos R, Cooperberg MR, Carroll PR, Nguyen HG, Greene KL, Langton-Webster B, Berkman CE, Seo Y.

J Nucl Med. 2019 Jul;60(7):910-916. doi: 10.2967/jnumed.118.220715. Epub 2018 Nov 21.


Uncommon malignant renal tumors and atypical presentation of common ones: a guide for radiologists.

Laguna B, Westphalen AC, Guimarães CT, Whang Z, Simko J, Zagoria R.

Abdom Radiol (NY). 2019 Apr;44(4):1430-1452. doi: 10.1007/s00261-018-1789-4. Review.


Diagnostic Accuracy of 68Ga-PSMA-11 PET/MRI Compared with Multiparametric MRI in the Detection of Prostate Cancer.

Hicks RM, Simko JP, Westphalen AC, Nguyen HG, Greene KL, Zhang L, Carroll PR, Hope TA.

Radiology. 2018 Dec;289(3):730-737. doi: 10.1148/radiol.2018180788. Epub 2018 Sep 18.


Targeting CD46 for both adenocarcinoma and neuroendocrine prostate cancer.

Su Y, Liu Y, Behrens CR, Bidlingmaier S, Lee NK, Aggarwal R, Sherbenou DW, Burlingame AL, Hann BC, Simko JP, Premasekharan G, Paris PL, Shuman MA, Seo Y, Small EJ, Liu B.

JCI Insight. 2018 Sep 6;3(17). pii: 121497. doi: 10.1172/jci.insight.121497. eCollection 2018 Sep 6.


Comparing Prognostic Utility of a Single-marker Immunohistochemistry Approach with Commercial Gene Expression Profiling Following Radical Prostatectomy.

Leapman MS, Nguyen HG, Cowan JE, Xue L, Stohr B, Simko J, Cooperberg MR, Carroll PR.

Eur Urol. 2018 Nov;74(5):668-675. doi: 10.1016/j.eururo.2018.08.020. Epub 2018 Sep 1.


STAG2 Is a Biomarker for Prediction of Recurrence and Progression in Papillary Non-Muscle-Invasive Bladder Cancer.

Lelo A, Prip F, Harris BT, Solomon D, Berry DL, Chaldekas K, Kumar A, Simko J, Jensen JB, Bhattacharyya P, Mannion C, Kim JS, Philips G, Dyrskjøt L, Waldman T.

Clin Cancer Res. 2018 Sep 1;24(17):4145-4153. doi: 10.1158/1078-0432.CCR-17-3244. Epub 2018 Jun 28.


The Diverse Genomic Landscape of Clinically Low-risk Prostate Cancer.

Cooperberg MR, Erho N, Chan JM, Feng FY, Fishbane N, Zhao SG, Simko JP, Cowan JE, Lehrer J, Alshalalfa M, Kolisnik T, Chelliserry J, Margrave J, Aranes M, Plessis MD, Buerki C, Tenggara I, Davicioni E, Carroll PR.

Eur Urol. 2018 Oct;74(4):444-452. doi: 10.1016/j.eururo.2018.05.014. Epub 2018 May 28.


Polyoma virus-associated carcinomas of the urologic tract: a clinicopathologic and molecular study.

Sirohi D, Vaske C, Sanborn Z, Smith SC, Don MD, Lindsey KG, Federman S, Vankalakunti M, Koo J, Bose S, Peralta-Venturina M, Ziffle JV, Grenert JP, Miller S, Chiu C, Amin MB, Simko JP, Stohr BA, Luthringer DJ.

Mod Pathol. 2018 Sep;31(9):1429-1441. doi: 10.1038/s41379-018-0065-z. Epub 2018 May 15.


Correlation of High-Risk Soft Tissue Sarcoma Biomarker Expression Patterns with Outcome following Neoadjuvant Chemoradiation.

Kane JM 3rd, Magliocco A, Zhang Q, Wang D, Klimowicz A, Harris J, Simko J, DeLaney T, Kraybill W, Kirsch DG.

Sarcoma. 2018 Feb 28;2018:8310950. doi: 10.1155/2018/8310950. eCollection 2018.


Management of Inverted Papilloma During Holmium Laser Enucleation of the Prostate.

Tzou DT, Cadwell C, Simko JP, Chi T, Stoller ML.

Urology. 2018 Jun;116:e5-e6. doi: 10.1016/j.urology.2018.01.009. Epub 2018 Mar 12.


Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer.

Sahoo D, Wei W, Auman H, Hurtado-Coll A, Carroll PR, Fazli L, Gleave ME, Lin DW, Nelson PS, Simko J, Thompson IM, Leach RJ, Troyer DA, True LD, McKenney JK, Feng Z, Brooks JD.

Oncotarget. 2018 Jan 5;9(5):6550-6561. doi: 10.18632/oncotarget.23973. eCollection 2018 Jan 19.


The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism.

Karesova I, Simko J, Fekete S, Zimcikova E, Malakova J, Zivna H, Pavlikova L, Palicka V.

Eur J Pharmacol. 2018 Apr 5;824:115-119. doi: 10.1016/j.ejphar.2018.02.010. Epub 2018 Feb 8.


Expression of the DNA repair gene MLH1 correlates with survival in patients who have resected pancreatic cancer and have received adjuvant chemoradiation: NRG Oncology RTOG Study 9704.

Lawrence YR, Moughan J, Magliocco AM, Klimowicz AC, Regine WF, Mowat RB, DiPetrillo TA, Small W Jr, Simko JP, Golan T, Winter KA, Guha C, Crane CH, Dicker AP.

Cancer. 2018 Feb 1;124(3):491-498. doi: 10.1002/cncr.31058. Epub 2017 Oct 20.


Characterization and stratification of prostate lesions based on comprehensive multiparametric MRI using detailed whole-mount histopathology as a reference standard.

Starobinets O, Simko JP, Kuchinsky K, Kornak J, Carroll PR, Greene KL, Kurhanewicz J, Noworolski SM.

NMR Biomed. 2017 Dec;30(12). doi: 10.1002/nbm.3796. Epub 2017 Sep 29.


Behavioral effects of antiepileptic drugs in rats: Are the effects on mood and behavior detectable in open-field test?

Zimcikova E, Simko J, Karesova I, Kremlacek J, Malakova J.

Seizure. 2017 Nov;52:35-40. doi: 10.1016/j.seizure.2017.09.015. Epub 2017 Sep 20.


The influence of fundamental frequency on perceived duration in spectrally comparable sounds.

Dawson C, Aalto D, Simko J, Vainio M.

PeerJ. 2017 Sep 1;5:e3734. doi: 10.7717/peerj.3734. eCollection 2017.


Renal NUT carcinoma: a case report.

Sirohi D, Garg K, Simko JP, Grenert JP.

Histopathology. 2018 Feb;72(3):528-530. doi: 10.1111/his.13368. Epub 2017 Nov 7. No abstract available.


Musical Sophistication and the Effect of Complexity on Auditory Discrimination in Finnish Speakers.

Dawson C, Aalto D, Šimko J, Vainio M, Tervaniemi M.

Front Neurosci. 2017 Apr 13;11:213. doi: 10.3389/fnins.2017.00213. eCollection 2017.


Pericytic tumors of the kidney-a clinicopathologic analysis of 17 cases.

Sirohi D, Smith SC, Epstein JI, Balzer BL, Simko JP, Balitzer D, Benhamida J, Kryvenko ON, Gupta NS, Paluru S, da Cunha IW, Leal DN, Williamson SR, de Peralta-Venturina M, Amin MB.

Hum Pathol. 2017 Jun;64:106-117. doi: 10.1016/j.humpath.2017.04.005. Epub 2017 Apr 21.


Novel missense variant of CACNA1A gene: A case report of a family with episodic ataxia type 2.

Sivák Š, Kurča E, Krajčiová A, Hikkelová M, Šimko J, Mišovicová N, Kantorová E, Turčanová-Koprušáková M, Burjanivová T, Čierny D, Nosál' V.

J Neurol Sci. 2017 May 15;376:119-120. doi: 10.1016/j.jns.2017.03.008. Epub 2017 Mar 11. No abstract available.


Connections of Grasping and Horizontal Hand Movements with Articulation in Czech Speakers.

Tiainen M, Lukavský J, Tiippana K, Vainio M, Šimko J, Felisberti F, Vainio L.

Front Psychol. 2017 Apr 5;8:516. doi: 10.3389/fpsyg.2017.00516. eCollection 2017.


Stability and Variability in Slovak Prosodic Boundaries.

Benuš Š, Šimko J.

Phonetica. 2016;73(3-4):163-193. doi: 10.1159/000446350. Epub 2017 Feb 23.


Application of a Prognostic Gleason Grade Grouping System to Assess Distant Prostate Cancer Outcomes.

Leapman MS, Cowan JE, Simko J, Roberge G, Stohr BA, Carroll PR, Cooperberg MR.

Eur Urol. 2017 May;71(5):750-759. doi: 10.1016/j.eururo.2016.11.032. Epub 2016 Dec 9.


Tissue Sources for Accurate Measurement of Germline DNA Genotypes in Prostate Cancer Patients Treated With Radical Prostatectomy.

Emami NC, Leong L, Wan E, Van Blarigan EL, Cooperberg MR, Tenggara I, Carroll PR, Chan JM, Witte JS, Simko JP.

Prostate. 2017 Mar;77(4):425-434. doi: 10.1002/pros.23283. Epub 2016 Nov 30.


MUC1 Expression by Immunohistochemistry Is Associated with Adverse Pathologic Features in Prostate Cancer: A Multi-Institutional Study.

Eminaga O, Wei W, Hawley SJ, Auman H, Newcomb LF, Simko J, Hurtado-Coll A, Troyer DA, Carroll PR, Gleave ME, Lin DW, Nelson PS, Thompson IM, True LD, McKenney JK, Feng Z, Fazli L, Brooks JD.

PLoS One. 2016 Nov 15;11(11):e0165236. doi: 10.1371/journal.pone.0165236. eCollection 2016.


The effect of lamotrigine and phenytoin on bone turnover and bone strength: A prospective study in Wistar rats.

Simko J, Karesova I, Kremlacek J, Fekete S, Zimcikova E, Malakova J, Zivna H, Valis M, Palicka V.

Epilepsy Res. 2016 Dec;128:113-118. doi: 10.1016/j.eplepsyres.2016.10.005. Epub 2016 Oct 24.


Systemic GM-CSF Recruits Effector T Cells into the Tumor Microenvironment in Localized Prostate Cancer.

Wei XX, Chan S, Kwek S, Lewis J, Dao V, Zhang L, Cooperberg MR, Ryan CJ, Lin AM, Friedlander TW, Rini B, Kane C, Simko JP, Carroll PR, Small EJ, Fong L.

Cancer Immunol Res. 2016 Nov;4(11):948-958. Epub 2016 Sep 29.


Histologic Grading of Prostatic Adenocarcinoma Can Be Further Optimized: Analysis of the Relative Prognostic Strength of Individual Architectural Patterns in 1275 Patients From the Canary Retrospective Cohort.

McKenney JK, Wei W, Hawley S, Auman H, Newcomb LF, Boyer HD, Fazli L, Simko J, Hurtado-Coll A, Troyer DA, Tretiakova MS, Vakar-Lopez F, Carroll PR, Cooperberg MR, Gleave ME, Lance RS, Lin DW, Nelson PS, Thompson IM, True LD, Feng Z, Brooks JD.

Am J Surg Pathol. 2016 Nov;40(11):1439-1456.


PTEN Loss as Determined by Clinical-grade Immunohistochemistry Assay Is Associated with Worse Recurrence-free Survival in Prostate Cancer.

Lotan TL, Wei W, Morais CL, Hawley ST, Fazli L, Hurtado-Coll A, Troyer D, McKenney JK, Simko J, Carroll PR, Gleave M, Lance R, Lin DW, Nelson PS, Thompson IM, True LD, Feng Z, Brooks JD.

Eur Urol Focus. 2016 Jun;2(2):180-188.


18F Fluorocholine Dynamic Time-of-Flight PET/MR Imaging in Patients with Newly Diagnosed Intermediate- to High-Risk Prostate Cancer: Initial Clinical-Pathologic Comparisons.

Choi JY, Yang J, Noworolski SM, Behr S, Chang AJ, Simko JP, Nguyen HG, Carroll PR, Kurhanewicz J, Seo Y.

Radiology. 2017 Feb;282(2):429-436. doi: 10.1148/radiol.2016160220. Epub 2016 Aug 11.


Loss of Expression of AZGP1 Is Associated With Worse Clinical Outcomes in a Multi-Institutional Radical Prostatectomy Cohort.

Brooks JD, Wei W, Pollack JR, West RB, Shin JH, Sunwoo JB, Hawley SJ, Auman H, Newcomb LF, Simko J, Hurtado-Coll A, Troyer DA, Carroll PR, Gleave ME, Lin DW, Nelson PS, Thompson IM, True LD, McKenney JK, Feng Z, Fazli L.

Prostate. 2016 Nov;76(15):1409-19. doi: 10.1002/pros.23225. Epub 2016 Jun 21.


Beyond Prostate Adenocarcinoma: Expanding the Differential Diagnosis in Prostate Pathologic Conditions.

Li Y, Mongan J, Behr SC, Sud S, Coakley FV, Simko J, Westphalen AC.

Radiographics. 2016 Jul-Aug;36(4):1055-75. doi: 10.1148/rg.2016150226. Epub 2016 Jun 17. Review.


Quantity language speakers show enhanced subcortical processing.

Dawson C, Aalto D, Šimko J, Putkinen V, Tervaniemi M, Vainio M.

Biol Psychol. 2016 Jul;118:169-175. doi: 10.1016/j.biopsycho.2016.06.003. Epub 2016 Jun 11.


Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH.

Lotan TL, Wei W, Ludkovski O, Morais CL, Guedes LB, Jamaspishvili T, Lopez K, Hawley ST, Feng Z, Fazli L, Hurtado-Coll A, McKenney JK, Simko J, Carroll PR, Gleave M, Lin DW, Nelson PS, Thompson IM, True LD, Brooks JD, Lance R, Troyer D, Squire JA.

Mod Pathol. 2016 Aug;29(8):904-14. doi: 10.1038/modpathol.2016.88. Epub 2016 May 13.


Prognostic value of Ki67 in localized prostate carcinoma: a multi-institutional study of >1000 prostatectomies.

Tretiakova MS, Wei W, Boyer HD, Newcomb LF, Hawley S, Auman H, Vakar-Lopez F, McKenney JK, Fazli L, Simko J, Troyer DA, Hurtado-Coll A, Thompson IM Jr, Carroll PR, Ellis WJ, Gleave ME, Nelson PS, Lin DW, True LD, Feng Z, Brooks JD.

Prostate Cancer Prostatic Dis. 2016 Sep;19(3):264-70. doi: 10.1038/pcan.2016.12. Epub 2016 May 3.


Prostate cancer with a pseudocapsule at MR imaging: a marker of high grade and stage disease?

Bonde AA, Korngold EK, Foster BR, Westphalen AC, Pettersson DR, Troxell ML, Simko JP, Coakley FV.

Clin Imaging. 2016 May-Jun;40(3):365-9. doi: 10.1016/j.clinimag.2015.12.015. Epub 2016 Jan 21.


Application of a Clinical Whole-Transcriptome Assay for Staging and Prognosis of Prostate Cancer Diagnosed in Needle Core Biopsy Specimens.

Knudsen BS, Kim HL, Erho N, Shin H, Alshalalfa M, Lam LLC, Tenggara I, Chadwich K, Van Der Kwast T, Fleshner N, Davicioni E, Carroll PR, Cooperberg MR, Chan JM, Simko JP.

J Mol Diagn. 2016 May;18(3):395-406. doi: 10.1016/j.jmoldx.2015.12.006. Epub 2016 Mar 3.


Mutational Landscape of Aggressive Prostate Tumors in African American Men.

Lindquist KJ, Paris PL, Hoffmann TJ, Cardin NJ, Kazma R, Mefford JA, Simko JP, Ngo V, Chen Y, Levin AM, Chitale D, Helfand BT, Catalona WJ, Rybicki BA, Witte JS.

Cancer Res. 2016 Apr 1;76(7):1860-8. doi: 10.1158/0008-5472.CAN-15-1787. Epub 2016 Feb 26.


A Molecular Model for Predicting Overall Survival in Patients with Metastatic Clear Cell Renal Carcinoma: Results from CALGB 90206 (Alliance).

Kim HL, Halabi S, Li P, Mayhew G, Simko J, Nixon AB, Small EJ, Rini B, Morris MJ, Taplin ME, George D; Alliance for Clinical Trials in Oncology.

EBioMedicine. 2015 Sep 8;2(11):1814-20. doi: 10.1016/j.ebiom.2015.09.012. eCollection 2015 Nov.


Hyperarticulation in Lombard speech: Global coordination of the jaw, lips and the tongue.

Šimko J, Beňuš Š, Vainio M.

J Acoust Soc Am. 2016 Jan;139(1):151-62. doi: 10.1121/1.4939495.


Patient-specific Meta-analysis of 2 Clinical Validation Studies to Predict Pathologic Outcomes in Prostate Cancer Using the 17-Gene Genomic Prostate Score.

Brand TC, Zhang N, Crager MR, Maddala T, Dee A, Sesterhenn IA, Simko JP, Cooperberg MR, Srivastava S, Rosner IL, Chan JM, Febbo PG, Carroll PR, Cullen J, Lawrence HJ.

Urology. 2016 Mar;89:69-75. doi: 10.1016/j.urology.2015.12.008. Epub 2015 Dec 23.


Associations between circulating carotenoids, genomic instability and the risk of high-grade prostate cancer.

Nordström T, Van Blarigan EL, Ngo V, Roy R, Weinberg V, Song X, Simko J, Carroll PR, Chan JM, Paris PL.

Prostate. 2016 Mar;76(4):339-48. doi: 10.1002/pros.23125. Epub 2015 Nov 20.

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